Volume 56, Issue 4

Yanli Liu, Hanhan Li, Yuyao Pei, Yong Wang, Changqing Yang, Tao Lu

pp. 907–916 · DOI: 10.5530/ijper.56.4.172 · 2022

Background: The Professional Master of Pharmacy (M. Pharm.) education program in China has undergone 10 years of development and has rapidly achieved great progress. The aim of this study was to summarize and introduce t…

Nidhi Gairola, Mahamedha Deorari, Vikash Jakhmola, Reema Sircar, Havagiray R Chitme

pp. 917–923 · DOI: 10.5530/ijper.56.4.173 · 2022

Introduction: In present situation infertility is one of the chief problem for reproductive couples due to multiple factors including lifestyle. Infertility is thought to be caused by both male and female factors in 27 p…

Pottathil Shinu, Anroop B Nair, Beena Kumari, Shery Jacob, Manish Kumar, Abhishek Tiwari, Varsha Tiwari, Katharigatta N Venugopala, Mahesh Attimarad, Sreeharsha Nagaraja

pp. 924–937 · DOI: 10.5530/ijper.56.4.170 · 2022

Both melanoma and non-melanoma are the most common types of skin cancers affecting various populations across the globe. Skin malignancy is more prevalent among Caucasian populations. Non-melanoma types of skin cancers a…

Shaweta Sharma, Akhil Sharma, Aftab Alam, Utsav Gupta

pp. 938–949 · DOI: 10.5530/ijper.56.4.174 · 2022

Aim: The present work aimed at the utilization of alternative animal models in research. Background: Animal models from a long time played an important role in drug and vaccine development. However, due to the limitation…

Pasupuleti Dheeraj Krishna, Deeksha Kethareshwara Sujatha, Balamuralidhara Veeranna

pp. 950–958 · DOI: 10.5530/ijper.56.4.175 · 2022

Background: Intellectual property rights (IPR) are described as concepts, creations, especially artistic endeavors around which the community is ready to confer the position of ownership. There are various sorts of intel…

Bowen Li, Wentao Yu, Jianming Jiang, Yixin Zhang, Jingshan Zhao

pp. 959–967 · DOI: 10.5530/ijper.56.4.176 · 2022

Background: Online teaching based on multiple platforms has become an important and respected teaching method. Aim: We aimed to investigate effect of “Super Star Learning System and QQ Group” online teaching model on lea…

Padma GM Rao, Syed Arman Rabbani

pp. 968–975 · DOI: 10.5530/ijper.56.4.177 · 2022

Introduction: Team-Based Learning (TBL) is an active-learning methodology that has been successfully employed in various health schools’ curricula. This study assessed the perception of pharmacy students studying in a Co…

Li Wang, Feng Pan, Jun Geng

pp. 976–983 · DOI: 10.5530/ijper.56.4.178 · 2022

Background: Bacterial meningitis is a serious medical disorder that should be treated as soon as possible. Aim: The effect of ansamycin as a nanoformulation on Escherichia coliinduced meningitis was investigated. Materia…

Keerthana K, Sandeep DS

pp. 984–993 · DOI: 10.5530/ijper.56.4.179 · 2022

Background: The aim of present study was to carry out the formulation design and evaluation of Solid Lipid Nanoparticles (SLNs) loaded topical gel of Flurbiprofen. Materials and Methods: Flurbiprofen solid lipid nanopart…

Challa Taraka Ramarao, Somireddy Madhuri

pp. 994–1002 · DOI: 10.5530/ijper.56.4.180 · 2022

Background: Levitiracetam is an antiepileptic medication that falls into the BCS Class I drug classification. It is used to treat specific types of seizures in adults and children with epilepsy because of its high solubi…

Sanat Kumar Dash, Chinam Niranjan Patra, Sasmita Kumari Acharjya, Goutam Kumar Jena, Kahnu Charan Panigrahi, Nandika Khirod Kumar, Partha Sarathi Das

pp. 1003–1012 · DOI: 10.5530/ijper.56.4.181 · 2022

Background: Paliperidone is indicated for the treatment of schizophrenia. It has an absolute oral bioavailability of about 28% as it is poorly soluble in water and also undergoes hepatic first-pass metabolism. Objectives…

Sowmya Priyadarsini, Swaroop Rameshwarji Lahoti

pp. 1013–1024 · DOI: 10.5530/ijper.56.4.182 · 2022

Aim: Hormone responsive breast cancer is the most prevalent cancer worldwide. Letrozole is a third-generation aromatase inhibitor widely used for the treatment of advanced breast cancer. The primary objective of the pres…

Sonam Sanjayrao Kunjekar, Dilesh Jagdish Singhavi, Tejaswini Balkrishna Parshuramkar, Shagufta Khan

pp. 1025–1030 · DOI: 10.5530/ijper.56.4.183 · 2022

Aim: Hypertension exhibits a circadian rhythm and drugs need to be released at the time when the blood pressure is elevated most. This elevation is pronounced at 7 pm and at 4 am. Atenolol is an anti-hypertensive drug wi…

Hadel A. Abo El-Enin, Amany Salah Khalifa

pp. 1031–1043 · DOI: 10.5530/ijper.56.4.184 · 2022

Background: Insomnia is usually associated with mental and physical daytime impairment. Zaleplon (Zp) is indicated in insomnia management but its limited aqueous solubility led to its low bioavailability (BAV) ~30%. Self…

Haranath Chinthaginjala, Mousami Bhavasar Telkar, Abdul Ahad Hindustan, Pradeepkumar Bhupalam

pp. 1044–1051 · DOI: 10.5530/ijper.56.4.185 · 2022

Objectives: The intention of present study is to formulate and optimize the famotidine mucoadhesive tablets y using Central Composite Design. Materials and Methods: The concentrations of Cordia dichotoma fruit mucilage p…

Devika Tripathi, Dinesh Kumar Sharma, Jagannath Sahoo, Sunil Kumar Raman

pp. 1052–1062 · DOI: 10.5530/ijper.56.4.186 · 2022

Background: Hydrotropic solid dispersion has been reported as a potential process to improve the poor solubility of drugs using conventional hydrotropes. The presented investigation has described a water-soluble hydrotro…

Priyadarshini Patel, Tejas Patel

pp. 1063–1075 · DOI: 10.5530/ijper.56.4.187 · 2022

Aim: The goal of this study was to develop colon-targeted nanoparticulate systems of the anti-inflammatory agent Quercetin (QU) and evaluate the formulation for various parameters that would allow the active ingredient t…

Mrugendra Bhojraj Potdar, Neetesh Kumar Jain, Kiran Dayaram Patil, Yogeeta Sameer Goyal

pp. 1076–1082 · DOI: 10.5530/ijper.56.4.188 · 2022

Intranasal drug delivery is a promising route for drug delivery directly to the brain for acute or chronic treatments. A direct route to the brain offers a rapid approach to delivering drugs to the central nervous system…

Reem I Alsantali, Hadel A Abo El-Enin

pp. 1083–1090 · DOI: 10.5530/ijper.56.4.189 · 2022

Background: Wearing a facemask is one of the precautionary measures for preventing coronavirus disease spread, which causes many facial skin adverse effects. Vitamin-E (TPGS) and olive oil have an efficient effect on ski…

Rajesh A. Maheshwari, Ashim Kumar Sen, Ramachandran Balaraman, Nirmal V. Shah, Umang H. Shah, Nilay Solanki, Dhanya B. Sen

pp. 1091–1098 · DOI: 10.5530/ijper.56.4.190 · 2022

Objectives: Diabetes is a major disease that causes a tremendous economic burden internationally. To tackle this horrible condition, good therapeutic intervention with nutraceutical is required. These include diabetic ne…