Volume 57, Issue 2

Original Article(continued)

1. Article

   Caryota urens and Hyophorbe lagenicaulis as Nutraceutical by Managing Commercially Available Drug Induced Nephrotoxicity

   Saumya Das, Richa Shakya, Avijit Mazumder, Anamaika Gautam

   pp. 503–510 · DOI: 10.5530/ijper.57.2.61 · 2023

   Background: Caryota urens flowers and Hyophorbe lagenicaulis leaves have huge beneficial properties, medicinal uses and rich phyto-pharmacological constituents. Nutraceutical potentiality of the selected plants on the ba…

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2. Article

   New Data for Endemic Phlomis cypria Post from North Cyprus: Biological Activities and LC MS/MS Analysis

   İmge Kunter, Mohammed Tamim Tarabishi, Niloufar Zabib, Tuğba Erçetin, Mehmet İlktaç, Fatih Göger, Müberra Koşar

   pp. 511–518 · DOI: 10.5530/ijper.57.2.62 · 2023

   Background: The genus Phlomis includes up to 100 species which are distributed throughout Eurasia. Of these species, Phlomis cypria Post (Lamiaceae) is an endemic plant from North Cyprus. P. cypria is commonly used in No…

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3. Article

   Evaluation of Nootropic Potential of the Fruits of Artocarpus altilis by in vivo and in vitro Studies

   Anil Kumar C, CS Shastry, Sharad Chand, Sawan Mukund Ghetia

   pp. 519–525 · DOI: 10.5530/ijper.57.2.63 · 2023

   Background: Artocarpus altilis is an evergreen plant having a variety of medicinal values due to the presence of compounds like cyclopropane sterols, quercetin, camphorol, artocarpine, and many more. The fruits typically…

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4. Article

   Anti-mitotic Activities of Ethanolic Extract and Glutinol from Uvaria rufa Blume

   Agnes B. Alimboyoguen, Kathlia A. De Castro-Cruz, Chien-Chang Shen, Po-Wei Tsai

   pp. 526–530 · DOI: 10.5530/ijper.57.2.64 · 2023

   Background: This study describes the isolation of major chemical constituent from the bark of Uvaria rufa Blume, commonly known as “allagat or susong kalabaw”, an indigenous Philippine medicinal plant that belongs to the…

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5. Article

   In vitro Antioxidant, Cytotoxicity Study on EAC Cell Line of Quinazolin-4(3H)-one Derivatives: Synthesis, Molecular Docking, in silico Drug Likeness

   Kavitha Kasimayan, Srinivasan Nagarajan, Suresh Ramalingam, Mohan Sellappan

   pp. 531–539 · DOI: 10.5530/ijper.57.2.65 · 2023

   Aim: The quinazolin-4(3)-one exist an important sort of therapeutic drug candidates which attain integer of biological actions. In this research intended on design, synthesis, and Drug likeness, screened their antioxidan…

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6. Article

   A Comparative Evaluation of Various Therapies of Synthetic Drugs with Amla and Honey Combination for the Treatment of Gastroesophageal Reflux Disease

   Avijit Mazumder, Naveen Kumar, Saumya Das

   pp. 540–546 · DOI: 10.5530/ijper.57.2.66 · 2023

   Background: Gastroesophageal Reflux Disease (GERD) is disorder of oesophagus that causes ulcer and erosion. Materials and Methods: A comparison based on the in vivo study was carried out to determine the therapeutic effi…

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7. Article

   Subtle Intricacies Identified during Streptozotocin-Induced Diabetes in Wistar Rats

   Bheemisetty Brahmam, Farmiza Begum, Dani Lakshman Yarlagadda, Rekha Raghuveer Shenoy, Shaila Angela Lewis

   pp. 547–551 · DOI: 10.5530/ijper.57.2.67 · 2023

   Aim: This study aimed to establish the dose of streptozotocin required to induce Type -1 diabetes in Wistar rats. Background: Streptozotocin is currently employed worldwide to induce insulin-dependent diabetes mellitus a…

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8. Article

   Synthesis and Biological Evaluation of the Selected Naphthalene Substituted Azetidinone Derivatives Targeting Parkinson’s Disease

   G Subramanian, J Chand, S Jupudi, P Prudviraj

   pp. 552–558 · DOI: 10.5530/ijper.57.2.68 · 2023

   Aim/Background: Parkinson’s Disease (PD), the loss of dopaminergic neurons in the substantial nigra part of the brain leading to neurodegeneration. Materials and Methods: The objective of this study was to observe the ne…

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9. Article

   New Eco-friendly UV-spectroscopic Methods for Simultaneous Assessment of Dapagliflozin, Saxagliptin and Metformin in Ternary Mixture

   Dhanya B Sen, Sohil Jatu, Rajesh A Maheshwari, Aarti Sachin Zanwar, Ramaswamy Velmurugan, Ashim Kumar Sen

   pp. 559–569 · DOI: 10.5530/ijper.57.2.69 · 2023

   Background and Aim: Qternmet XR® consisting of dapagliflozin (10 mg), saxagliptin (5 mg), and metformin hydrochloride (1000 mg), is a fixed-dose combination (tablets) that improves glycemic control in individuals with di…

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10. Article

    Chemometrics Assisted Spectrophotometric Method Development and Validation for Simultaneous Estimation of Abacavir, Lamivudine and Dolutegravir in Dosage Form

    Sapna Rathod, Paresh Patel, Nisarg Patel

    pp. 570–582 · DOI: 10.5530/ijper.57.2.70 · 2023

    Aim: Multivariate methods, particularly Classical Least Square, Inverse Least Square (ILS), Partial Least Square and Principal Component Regression are invented for the quantitation of the Abacavir sulphate (ABA), Lamivu…

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11. Article

    Discrimination of Different Part of Curcuma longa by HPLC Fingerprints Combined with Multivariate Statistical Analysis

    Jiuhua Song, Dabing Xiang, Ying Cheng, Yuan Fang, Yinghong Wang, Kai Shi

    pp. 583–590 · DOI: 10.5530/ijper.57.2.71 · 2023

    Aim: The purpose of this study is to develop a method to explore the difference between the rhizomes and tuberous roots of Curcuma longa, and screen out the difference markers. Materials and Methods: The quantitative ana…

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12. Article

    The Impact of an Educational Module on Pharmacovigilance towards Improving Knowledge and Attitude of Nursing and Pharmacy Students

    Megaravalli Ramesh Manasa, Sujith John Chandy, Santosh Ramakrishnan Pillai

    pp. 598–602 · DOI: 10.5530/ijper.57.2.73 · 2023

    Background: Pharmacovigilance is an integral part of patient safety and rational use of medicines. It is the professional responsibility of not just physicians but also of other health care professionals who use medicine…

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13. Article

    Enhancing Pharmaceutical Supply Chain Resilience: A Study of Pharmaceutical Companies in Multiple Geographies

    Hima Gupta, Ravindra Asharam Kayande

    pp. 603–611 · DOI: 10.5530/ijper.57.2.74 · 2023

    Background: Pharmaceutical businesses had enormous difficulties in product distribution during COVID-19, and the solution to this perpetual issue is a resilient supply chain. Aim: The study aims to understand the vulnera…

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14. Article

    Clinical Pharmacist Led Approach on Enhancement of Medication Adherence Resolving the Drug Related Problems with Selective Serotonin Reuptake Inhibitors among the Patients with Psychiatric Illness. A Prospective, Pre and Post Non-Randomised Interventional Study

    Pratheeksha T John, Varsha Mariam John, K Gowtham, Ashish Singh Parihar, Ramesh Bhandari, M S Ganachari

    pp. 612–616 · DOI: 10.5530/ijper.57.2.75 · 2023

    Introduction: Non-adherence is one of the most common barriers to the successful completion of treatment and it can be worst in psychiatric patients. Objectives: To assess, compare and resolve drug-related problems and m…

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15. Article

    Impact of Regulatory Policy Changes on Generic Drug Prices in the United States

    Rajender Singh, Swati Singh, Anil Kumar, GT Kulkarni, Arti R Thakkar

    pp. 617–624 · DOI: 10.5530/ijper.57.2.76 · 2023

    Introduction: Generic Drug User Fee Act (GDUFA) was introduced in 2012 to bring more and more generic drugs into the market in a short time through an effective review process. In the present study, the impact of the GDU…

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