Volume 57, Issue 2S

Sonali S Sonawane, Prashant L Pingale, Sunil V Amrutkar

pp. s189–s197 · DOI: 10.5530/ijper.57.2s.23 · 2023

Aim: This article describes how biodegradable polymers and their drug delivery mechanisms can be used to monitor and maintain local or targeted drug distribution. Polylactic-co-glycol acid has been one of the most appeal…

Ayusman Swain

pp. s226–s233 · DOI: 10.5530/ijper.57.2s.26 · 2023

Natural products are reported to have a vital role in the treatment of various diseases and drug design. In recent developments, natural drug molecules of plant origin have been reported exclusively for diabetic manageme…

Aditya Sharma, Navneet Verma

pp. s234–s243 · DOI: 10.5530/ijper.57.2s.27 · 2023

Background: The objective of this current study was to fabricate and characterize the sustained release double layered transdermal patches of Diclofenac Diethylamine using hydrophobic acrylic polymer Eudragit RL 100 and …

Sheeja Koliyote, Jessy Shaji

pp. s198–s212 · DOI: 10.5530/ijper.57.2s.24 · 2023

Despite advances in synthetic medications, medicinal herbs have empowered mankind with a wide range of efficacious medicines to lessen or eliminate illnesses and suffering from diseases. Since the last decade there has b…

Kunal V Bhambar, Rajendra S Bhambar, Pravin P Gadakh

pp. s244–s249 · DOI: 10.5530/ijper.57.2s.28 · 2023

Background: Baclofen is used as skeletal muscle relaxant. Baclofen inhibit Polysynaptic and monosynaptic reflexes a hyperpolarisation. Baclofen drug absorbed rapidly and excreted in feces urine in unchanged form. Objecti…

Harsha Kathpalia, Aditi Venkatesh, Neha Sathe

pp. s250–s261 · DOI: 10.5530/ijper.57.2s.29 · 2023

Introduction: Clotrimazole is a weak base and is practically insoluble in water. To enhance drug loading of hydrophobic Clotrimazole in the formulation and, to circumvent greasiness, poor retention time and easy wipe off…

R Prasanthi, B Haarika, S Selvamuthukumar

pp. s262–s273 · DOI: 10.5530/ijper.57.2s.30 · 2023

Introduction: Rasagiline mesylate is primarily prescribed to treat the symptoms of idiopathic Parkinson's disease works as irreversible inhibitor of mono amino oxidase. The microspheres were designed for extended retenti…

Shreyashi Mazumdar, Bala Prabhakar, Shraddha Ishwar Khairnar, Kavita Singh

pp. s274–s280 · DOI: 10.5530/ijper.57.2s.31 · 2023

Objectives: Mouth ulcer is a rupture or breaks in the oral mucosal membrane and it leads to atrophy and ulcers in the oral cavity. It increases the risk of infections with the Candida species Inherited trauma and aphthou…

Mahendra Gunde, Darshan Telange, Awdhut Pimpale, Anil Pethe

pp. s281–s291 · DOI: 10.5530/ijper.57.2s.32 · 2023

Background: Topical gels are an efficient and targeted therapy for local dermatological problems because they distribute medications effectively and are easy to wipe off the skin. The presented study was aimed to use Qua…

Khushbu R Chaudhari, Jignasa K Savjani, Ketan T Savjani, Sandeep Dahiya, Jitendra O Bhangale

pp. s292–s300 · DOI: 10.5530/ijper.57.2s.33 · 2023

Introduction: Drug-drug cocrystals of Lopinavir and Ritonavir were designed and characterized. In view of literature, Ritonavir increases the oral bioavailability of Lopinavir in low dosage. Aim: The present research aim…

Y Dinesh, Satheesh Kumar Balu, Karthikeyan Ramalingam, Pratibha Ramani

pp. s301–s306 · DOI: 10.5530/ijper.57.2s.34 · 2023

Aim/Background: Hydroxyapatite is a bioactive, biocompatible, and osteoconductive component having similar chemical characteristics to bone and tooth mineral components. Due to its porous structure and resistance to high…

Afzal Haq Asif, Girish Meravanige, Sreeharsha Nagaraja, Arshia Shariff, Juturu Thimmasetty, Kavitha Arenur Narayana

pp. s307–s314 · DOI: 10.5530/ijper.57.2s.35 · 2023

Background: Pulmonary diseases that affect the normal functioning of the lungs show airway symptoms ranging from change in airflow to bronchiectasis. Zileuton is an inhibitor of 5-lipoxygenase enzyme that catalyzes the s…

Zafar Ali Khan, Namdeo Prabhu, Naseer Ahmed, Rakhi Issrani

pp. s315–s320 · DOI: 10.5530/ijper.57.2s.36 · 2023

Background: Alveolar osteitis is a painful condition that occurs after tooth extraction. This condition has been treated with various chemical and herbal formulations that are found to be efficacious with different succe…

Ardana Tri Arianto, Soetrisno, Purwoko, Dono Indarto

pp. s321–s326 · DOI: 10.5530/ijper.57.2s.37 · 2023

Introduction: Traumatic Brain Injury (TBI) conditions require immediate treatment such as the administration of analgesics and sedation, including remifentanil. TBI will affect the levels of several inflammatory and apop…

Gunaswetha Kuraganti, Sujatha Edla, Swetha Viddamuri

pp. s327–s334 · DOI: 10.5530/ijper.57.2s.38 · 2023

Introduction: Over the past 60 years, numerous modern types of antibiotics have been developed. Antibiotic overuse has been largely responsible for spreading resistant strains that endangering the public's health at an a…

Alok Kumar Giri, Bhagyashree Biswal, Biswajit Jena, Laxmikanta Acharya

pp. s335–s344 · DOI: 10.5530/ijper.57.2s.39 · 2023

Background: Averrhoa carambola L. (star fruit) is an underutilized plant in the family Oxalidaceae. The plant has various pharmacological activities and has fleshy juicy fruit with high nutritional value and is rich in v…

Sandhiya Mathiyazhagan, Hrishita Yadav, Ramya Vishwanathan, Amala Reddy

pp. s345–s352 · DOI: 10.5530/ijper.57.2s.40 · 2023

Aim/Background: Plant-based medicines have gained remarkable recognition recently, as consumers have begun to express their preference for herbal remedies. C. bonducella, commonly known as fever nut, is said to have mass…

Ashish, Avijit Mazumder, Sanjita Das

pp. s353–s359 · DOI: 10.5530/ijper.57.2s.41 · 2023

Introduction: Globally, approximately 11% of the population has been affected by the irritable bowel syndrome. Recent advancement in medical area have made it easily possible to find out the proper pathophysiology behind…

G Sivakumar, S Anjala Devi

pp. s360–s369 · DOI: 10.5530/ijper.57.2s.42 · 2023

Aim: To investigate chemo-preventive effect of methanolic fruit extract of Cucumis melo var. agrestis on DEN (diethyl-nitrosamine) induced hepatocellular carcinoma in Sprague Dawley rats. Materials and Methods: Five grou…

Sribatsa Lanchhana Dash, Ranjit Mohapatra, Suman Kumar Mekap, Smruti Ranjan Masanta, Arpit Katiyar, Nitin Sharma, Ritu Karwasra, Sagar Kumar Mishra

pp. s370–s380 · DOI: 10.5530/ijper.57.2s.43 · 2023

Aim: The aim of the current study is to investigate the acute, sub-acute and sub-chronic toxicity study of extracts (n-hexane and chloroform) of L. camara in Wistar rats. Materials and Methods: HPTLC and GC-MS analysis w…