Volume 58, Issue 3S

Pooja Mallya, Shaila A Lewis

pp. s683–s692 · DOI: 10.5530/ijper.58.3s.72 · 2024

In recent years, dyslipidemia, a major risk factor for cardiovascular diseases is on the rise globally due to sedentary lifestyles and unhealthy diets. Though abundant data pertaining to the factors influencing dyslipide…

Pattilthodika Suhail, Velappan Venkatachalam Venkatachalam, Thirumalaisamy Balasubramanian, Parayil Varghese Christapher

pp. s693–s703 · DOI: 10.5530/ijper.58.3s.73 · 2024

Annona muricata Linn. (A. muricata) is a tropical evergreen fruit tree belonging to Annonaceae family, also referred as graviola, soursop or corossol. The chemical compounds isolated from this plant have linked to the et…

Ravi Kant Nishad, Kunwar Abhishek Singh, Md Azizur Rahman

pp. s704–s719 · DOI: 10.5530/ijper.58.3s.74 · 2024

The Research and Development in benzothiazole-based medicinal ingredients have turn into a hastily on the rise and gradually more lively topic. Broad number of compounds having Benzothiazole (BTZ) moiety are involved in …

Ouederni Ahmed Ridha El, Rania Omrani, Nour El Ouederni, Yasmine El Ouederni, Aida Katar, Noureddine Amdouni, Abderrazak Hedhili

pp. s720–s731 · DOI: 10.5530/ijper.58.3s.75 · 2024

In the present work, a bibliographical survey of the toxicity of some plants of the southern Tunisia’s flora was conducted on several methanoic extracts from miscellaneous toxic plants of the southern Tunisian flora and …

Saba Beigh

pp. s732–s756 · DOI: 10.5530/ijper.58.3s.76 · 2024

Introduction Dioxins represent a category of enduring environmental contaminants that possess the capability to elicit endocrine disruptions and a spectrum of ailments, most notably encompassing malignancies, immunologic…

Varsha Sahu, Sunit Kumar Sahoo, Amaresh Chandra Sahoo

pp. s757–s767 · DOI: 10.5530/ijper.58.3s.77 · 2024

In the pharmaceutical field, various diagnostic tools and delivery systems are available which used for the identification of diseases and treatment. Aquasome is a new type of vesicular drug delivery system. It is a self…

Amaresh Prusty, Susanta Kumar Panda

pp. s757–s767 · DOI: 10.5530/ijper.58.3s.78 · 2024

The traditional drug discovery process is expensive, time-consuming, and often leads to a high failure rate. The development of numerous new medications in the pharmaceutical sciences is only one example of how the advan…

Shuvranshu Praharaj, Vandurayanpet Kaliyamoorthy Kalaichelvan, Vedigounder Murugan, Velappan Venkatachalam, Ishtiyaque Ahmad

pp. s777–s786 · DOI: 10.5530/ijper.58.3s.79 · 2024

Background Depression is a common mental illness, with an estimated 3.8% of global population affected. In the pathophysiology of depression, ketamine acts quickly in patients. Treatment with low-dose ketamine upon admin…

Vanita Dnyandev Jadhav, Lalit Vasantrao Patil

pp. s787–s795 · DOI: 10.5530/ijper.58.3s.80 · 2024

Aim/Background In this work, a novel method for improving the quality of healthcare in the diagnosis of Interstitial Lung Disease (ILD) using High-Resolution Computed Tomography (HRCT) images is proposed. Materials and M…

Arwa Alshargabi, Wafa Mohammed Al-Madhagi, Abdulkarim Kassem Alzomor

pp. s796–s804 · DOI: 10.5530/ijper.58.3s.81 · 2024

Background and Objectives Hemorrhoids are defined as swollen veins in the anus and lower rectum. Hemorrhoids are a common medical problem and have a negative impact on people’s lives. The drugs that are available on the …

Mahesh Attimarad, Bandar Aldhubiab, Sreeharsha Nagaraja, Shinu Pottathil

pp. s796–s804 · DOI: 10.5530/ijper.58.3s.82 · 2024

Background The combination of two drugs celecoxib + tramadol and diclofenac sodium + tramadol with different mechanisms of action is better for achieving effective pain control. Materials and Methods The simple reproduci…

Naif Al Qurashi

pp. s815–s827 · DOI: 10.5530/ijper.58.3s.83 · 2024

Background Bovine Albumin Nanoparticles (BAN) have a high magnetic susceptibility and great potential for biomedical applications. Aim Evaluate the in vitro effects of magnetic BAN on mouse renal and submandibular cells.…

Pamujula Naga Haritha, Kunchithapatham Janakiraman, Katla Venu Madhav, Padavala Sunil Kumar Chaitanya

pp. s815–s827 · DOI: 10.5530/ijper.58.3s.84 · 2024

Background The therapeutic efficacy of an active Pharmaceutical ingredient depends on its solubility in body fluids. The low bioavailability of nearly 90% of new active Pharmaceutical ingredients and 40% of the existing …

Baburao Nanasaheb Chandakavathe, Ravindra Kulkarni, Akash Dadanna Rajmane, Snehal Limbraj Mane, Nishigandha Jayant Waykule

pp. s837–s847 · DOI: 10.5530/ijper.58.3s.85 · 2024

Background Even though the natural polymers are biodegradable, non-toxic and cost effective, but these suffer with some of drawbacks like uncontrolled drug release, enzymatic degradation, reduction in viscosity on long t…

Soji Soman, Aysha Padinhar Basheer, Geethu Mol, Luthfa Ahamed Muneer, Mariyammath Rafeeqa Khazi Abdul Rahiman, Gasper Fernandes, Srinivas Mutalik

pp. s848–s860 · DOI: 10.5530/ijper.58.3s.86 · 2024

Aim Using atenolol as a model active pharmaceutical and galactomannan from the seeds of Trigonella foenumgraecum as a mucoadhesive polymer, an effort was made to develop a gastroretentive bioadhesive floating delivery sy…

Poonam Sharma, Chitra Kaundal, Shweta Agarwal

pp. s861–s871 · DOI: 10.5530/ijper.58.3s.87 · 2024

Objectives Rebamipide, a gastroprotective drug, is used for preventing and treating ulcers but it has low aqueous solubility leading to poor bioavailability (10%). It acts both locally and systemically to provide gastrop…

Mansi Butola, Ashutosh Badola, Nidhi Nainwal, Shilpa Rana, Vikash Jakhmola, Yogita Ale, Arif N. M. Ansori

pp. s872–s879 · DOI: 10.5530/ijper.58.3s.88 · 2024

Background Tolperisone Hydrochloride (HCl) is a muscle relaxant that relaxes muscles by acting on the Central Nervous System (CNS). It acts at the spinal cord level by blocking calcium and sodium channels. It primarily i…

Bindhu Booraguntae Mohana, Eswar Gupta Maddi, Raman Dang

pp. s880–s889 · DOI: 10.5530/ijper.58.3s.89 · 2024

Background/Aim The aim of the study was to improve the dissolution profiles of Oxcarbazepine (OXC) from its tablets. This study was done to evaluate the effects of different formulation variables, i.e. type of non-volati…

Naif Al Qurashi

pp. s890–s899 · DOI: 10.5530/ijper.58.3s.90 · 2024

Background The biochemistry of secondary metabolites of marine origin has been identified as a promising area for obtaining new and potent pharmaceutical agents. These secondary metabolism molecules may have important fu…

Sumathi Raguraman, Hesham S Almoallim, Tahani Awad Alahmadi, Samer Hasan Hussein-Al-Ali, Muruganantham Bharathi, Arun Kumar Ramu

pp. s900–s909 · DOI: 10.5530/ijper.58.3s.91 · 2024

Introduction A major feature of drug-resistant cancer is the overexpression of transcription factors. During the study, reserpine, an indole alkaloid, was examined for its anticancer effects on cancer with drug resistanc…