Volume 58, Issue 3

Rajaram Mohapatra, Pratikeswar Panda, Sudhansu Sekhar Rout

pp. 695–708 · DOI: 10.5530/ijper.58.3.78 · 2024

Breast carcinoma is the world’s most prevalent type of cancer.The building of predictive cytotoxicity breast cancer models assists permanent synthetic activities and give critical information about structure-activity of …

Abdul Baquee Ahmed, Purbajit Chetia, Hemen Kalita

pp. 709–721 · DOI: 10.5530/ijper.58.3.79 · 2024

Background Rheumatoid Arthritis (RA) is a chronic form of inflammatory disorder where the immune system causes the destruction of bones and cartilage in joints and impacts the quality of life. Few studies have explored t…

Chunyan Wei, Ruofei Li, Zhiang Wu, Guirong Xiao, Ming Hu

pp. 722–729 · DOI: 10.5530/ijper.58.3.80 · 2024

Background To evaluate the value of pharmaceutical care, and sort out the existing problems in the current researches. Materials and Methods We established the research strategy and searched seven databases. Two reviewer…

Kang Min Kim, Shugeng Cao, Jae Sung Pyo

pp. 730–735 · DOI: 10.5530/ijper.58.3.81 · 2024

Aim This study aimed to qualitatively identify the ranges of the factors involved in the tablet compression process for ivabradine Sustained Release (SR) tablets. Materials and Methods A full factorial design of experime…

Sai Ramya Srikakulam, Jyothirmayee Devineni, Chandana Mokkapati, Yaswanth Venigalla, Aparna Pothuri, Anuhya Acchi, Sushil Sharma

pp. 736–750 · DOI: 10.5530/ijper.58.3.82 · 2024

Objectives The present study investigated the alternate route of delivery to avoid first pass metabolism and to increase bioavailability by nanosized Liposomes (LP) with Microneedles (MNs) Assistance for the Delivery of …

Gurpreet Kandav, Anjali Kumari Lochab, Tamanna Sharma

pp. 751–759 · DOI: 10.5530/ijper.58.3.83 · 2024

Aim Glaucoma treatment often involves the topical application of Timolol maleate (TM) to the eye. However, achieving the desired bioavailability via the ocular route can be challenging due to poor retention and penetrati…

Maged Mohammed Abdo Mohsen, K. Nagasree, Amit B. Patil

pp. 760–770 · DOI: 10.5530/ijper.58.3.84 · 2024

Introduction Vinorelbine tartrate is used as a first-line treatment in conjunction with conventional treatments, especially advanced disease including cancer patients. Objectives The objective of the study was to develop…

Yanjing Guo, Ningning Li, Xingyu Chen, Tao Wang, Wenping Zhang, Lihua Wu

pp. 771–783 · DOI: 10.5530/ijper.58.3.85 · 2024

Background The primary goal of the current investigation is to fabricate a transdermal NFs patch-based drug delivery system using Poly-N-Vinyl Caprolactam (PNVCL) blended with sodium alginate to prepared transdermal nano…

Sadhana Noothi, Narender Malothu, Vishnu Pulavarthy, BVS Praveen

pp. 784–793 · DOI: 10.5530/ijper.58.3.86 · 2024

Background Rosuvastatin (ROS) is an anti-hyperlipidaemic drug which reduces cholesterol levels, having poor solubility and low bioavailability (<20%). The objective of the present study was to increase ROS bioavailabilit…

Mustafa Ferudun Çelikmen, Sezgin Sarikaya, Doğaç Niyazi Özüçelik, Fadime Canbolat, Engin Sümer, Elif Çiğdem Keleş, Deniz Sema Maktav Çelikmen

pp. 794–801 · DOI: 10.5530/ijper.58.3.87 · 2024

Aim The aim of this study is to investigate the effects of Normal Saline (NS), Activated Charcoal (AC) and Intravenous Lipid Emulsion (ILE) in colchicine poisonings that resulted in death. Study Design The research is an…

Mengmeng Xing, Chuanshun Xiao, Xiangzhong Liu Yongmei Wang

pp. 822–829 · DOI: 10.5530/ijper.58.3.90 · 2024

Objectives Hepatitis B cirrhosis is a serious condition caused by the hepatitis B virus, leading to liver fibrosis and vascular proliferation. Current clinical treatments still have limitations, prompting interest in mic…

Wichuda Phiphitphibunsuk, Benjaporn Buranrat

pp. 861–869 · DOI: 10.5530/ijper.58.3.94 · 2024

Background Plumbago indica L. (PI) is a Thai traditional medicine that has been reported to improve health benefit including anticancer property. Nevertheless, the effects of PI and this mechanism are still less data in …

Yan Chen, Guanglu Zhang, Rijing Liang, Yao Shen, Xia Jiao

pp. 882–889 · DOI: 10.5530/ijper.58.3.96 · 2024

Background Diabetic Nephropathy (DN) is a common problem in diabetes and is characterized by glomerular dysfunction, hyperfiltration, and ultimately kidney failure. Objectives The present study was intended to understand…

Mohammed Albratty, Hafiz A Makeen

pp. 890–898 · DOI: 10.5530/ijper.58.3.97 · 2024

Background A highly malignant tumor, Breast Cancer (BC) has a poor prognosis for patients with the highest mortality rates in women. BC is currently treatable with a limited number of therapeutic strategies. Aim Natural …

Guanglu Zhang, Yan Chen, Huiliu An, Nan Hao, Haitao Shi

pp. 899–907 · DOI: 10.5530/ijper.58.3.98 · 2024

Background One of the most effective anti-cancer medications used to treat various cancers is Cisplatin (CP). Due to its nephrotoxicity, its usage is restricted. The purpose of this investigation is to assess Marrubiin’s…

Sonal Zambrekar, Leena Sawaikar, Swati Keny, Pradnya Pal, Surashree Gaude

pp. 908–917 · DOI: 10.5530/ijper.58.3.99 · 2024

Aim The objective of the current work was to develop and statistically validate a second order derivative method for estimating atenolol in tablet dosage form using UV spectrophotometry. Materials and Methods The method …

Hemlata Nimje, Mayuri Magar, Pranita Kamble, Niharika Rongali

pp. 918–924 · DOI: 10.5530/ijper.58.3.100 · 2024

Objectives The present goal of this analytical study is to develop a simple, reliable, sensitive and robust method that can identify Rivaroxaban (RVB) by using high performance thin liquid chromatography. The current stu…

Palanisamy Amirthalingam, Ahmed Mohsen Hamdan, Shahul Hameed Pakkir Mohamed, Vinoth Prabhu Veeramani, Mathar Mohideen Nagoor Thangam, Majed Falah Alanazi, Muralikrishnan Dhanasekaran, Vasudevan Mani, Saleh Fahad Alqifari, Mostafa Abdelrahman Sayed Ali

pp. 931–939 · DOI: 10.5530/ijper.58.3.102 · 2024

Background Virtual simulation has been widely used in various pharmacy educational institutions worldwide, and it helps students approach the real-world pharmacy practice experience. However, the importance and practice …

Pankaj Sharma, Abhishek Jain, Shiv Kumar Sharma, Satyendra Kumar Sharma, Abhishek Parashar

pp. 940–948 · DOI: 10.5530/ijper.58.3.103 · 2024

Background The process for choosing the right talent to further the institution’s objectives is known as faculty selection. In a pharmacy or engineering college, choosing teaching personnel is quite important. The best-q…

Priti Dhande, Sushila Kawade, Akshay Chaudhari

pp. 949–953 · DOI: 10.5530/ijper.58.3.104 · 2024

Background At the study site, Quality team found many incident reports of bleeding due to increased INR in patients on Warfarin anticoagulation therapy. These patients were unaware about adverse effects of anticoagulatio…