Volume 58, Issue 3

Original Article(continued)

1. Article

   Evaluation of Clinical Diagnosis Effect of Intracranial Aneurysms Combined with Artificial Intelligence Assistant Diagnosis System

   Qiang Li, Chunmiao Wu, Yuhao He, Shengming Liu, Sunfu Zhang

   pp. 954–964 · DOI: 10.5530/ijper.58.3.105 · 2024

   Objectives An intracranial aneurysm, usually referred to as an abnormal bulge in the wall of an intracranial artery, is the number one cause of subarachnoid hemorrhage and ranks third among cerebrovascular accidents afte…

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2. Article

   Evaluation of Pomegranate Seed Extract as a Tyrosinase Inhibitor for Hyperpigmentation Treatment

   Veerabhuvaneshwari Veerichetty, Lawanya Sivaraman, Sabarna Jeyasaravanan, Thenujaa Dharmalingam, Hesham S. Almoallim, Hossam M. Aljawdah

   pp. 965–975 · DOI: 10.5530/ijper.58.3.106 · 2024

   Background Melanin is a natural pigment found in various parts of the human body, which gives our skin, hair and eyes their color and protects the skin from ultraviolet light. Hyperpigmentation refers to a common skin co…

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3. Article

   Synthesis and Antinociceptive Activity of 5-Amino (N-Substitutedcarboxamide)quinoline Derivatives Targeting TRPV1 Receptor

   Megha Pankaj Ambatkar, Rishabh Devendra Agade, Pramod Bhujangrao Khedekar

   pp. 976–983 · DOI: 10.5530/ijper.58.3.107 · 2024

   Background Quinoline is a significant heterocyclic moiety involved in several biological activities including inhibition of transient receptor potential vanilloid 1. Materials and Methods A series of 5-amino( N-substitut…

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4. Article

   Development and Validation of a Sensitive, Fast and Simple LC-MS/MS Method for the Quantitation of Favipiravir Pure and Tablet Dosage Forms

   Naidu Srinivasa Rao, Anil Kumar Adimulapu, M. Roja Kumari, Pallepogu Venkateswara Rao, Abbineni Anusha, Daveedu Thathapudi

   pp. 984–990 · DOI: 10.5530/ijper.58.3.108 · 2024

   Objectives The analytical method development and validation for the determination of Favipiravir (FVPR) in pure and tablet dosage forms by LC/MS-MS Technique. Materials and Methods A simple LC-MS/MS method was developed …

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5. Article

   Application of Mechanistic Pharmacokinetic Model for the Optimization of Metformin Delayed Release Dosage Form for Intestinal Targeting

   Rajkumar Malayandi, Anumol Joseph, Sideequl Akbar, Subramanian Natesan, Ravichandiran Velayutham

   pp. 991–1001 · DOI: 10.5530/ijper.58.3.109 · 2024

   Background Metformin (MET) is a widely prescribed drug for managing Type 2 Diabetes Mellitus (T2DM). Despite the rich clinical experience and advantages, the clinical utility of MET in renal failure patients is limited b…

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6. Article

   The Postgraduate Community Pharmacy Education System: Commentary on the Swiss System

   Noelia Amador-Fernández, Talitha Villien de Gabiole, David Steeb, Jérôme Berger

   pp. 1002–1006 · DOI: 10.5530/ijper.58.3.110 · 2024

   Postgraduate education is recognized to improve communication and clinical skills and to have a positive impact on pharmacists’ professional activities and responsibilities. The purpose of this commentary is to present t…

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1. Article

   Inhibiting Cancer Progression through Targeting HDAC2 with Novel Ligands: A Dynamic Insights through Virtual Screening and Simulation

   Ayyub Ali Patel, Hani Alothaid, Ayaz Khurram Mallick, Adel Ibrahim Alalawy, Rasha Tarek Mirdad, Mahmoud Tarek Mirdad, Mohammed Tarek Mirdad, Marya Ahsan, Mohammed Tarique

   pp. 802–813 · DOI: 10.5530/ijper.58.3.88 · 2024

   Background Cancer is a multifaceted disease characterized by uncontrolled cell growth and represents a significant global health challenge. The intricate origins of cancer involve various factors that may act independent…

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2. Article

   METTL14-Mediate the Biological Effects of EMT in Bladder Cancer Cells by Methylating SOX4 mRNA with m6A

   Mengliang Xie, Huantao Zhang

   pp. 814–821 · DOI: 10.5530/ijper.58.3.89 · 2024

   Objectives Bladder Cancer (BC) is one of the most common malignant tumours of urinary system, with high rates of metastasis and mortality. Methyltransferase-like 14 (METTL14) is an RNA N6-adenosine methyltransferase that…

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3. Article

   Anticancer and Hepatoprotective Role of Selenium Nanoparticles against Liver Carcinogen Acrylamide Induced Toxicity: In vitro and in vivo Studies

   Uzma Faridi, Nahla Zidan, Hebbatallah Atteia, Yahya Al-Awthan, Adel I Alalawy, Md. Qussen Akhtar, Mohamed Sakran, Humaira Parveen

   pp. 830–836 · DOI: 10.5530/ijper.58.3.91 · 2024

   Background and Objectives Selenium is considered one of the essential components of many enzymes, particularly the antioxidant enzymes such as thioredoxin reductase. Vegetables, among other food sources, are common sourc…

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4. Article

   Design and Synthesis of Novel Series of Thiophene-2, 5-dicarbohydrazide Derivatives as Potential Anticancer Agents

   Vaibhav Gawade, Vitthal Chopade

   pp. 837–853 · DOI: 10.5530/ijper.58.3.92 · 2024

   Background The biological activity of thiophene and carbohydrazide derivatives is well known; some of them are included in various anticancer drugs. Objectives The main goal of this work was to develop effective, effecti…

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5. Article

   Lithotriptic Effect of Cinnamomum verum and Nigella sativa on Ureteric Calculi

   Mrinal Sanaye, Nikhat Khan, Dinesh Dhodi, Saleha Parveen

   pp. 854–860 · DOI: 10.5530/ijper.58.3.93 · 2024

   Introduction Urolithiasis is one of the most prevailing diseases in the society. Conventional treatments are symptomatic and are not targeted to direct the dissolution of ureteric calculi. Thus, in this study plants like…

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6. Article

   Headspace SPME-GC-MS Analysis and in silico Molecular Docking Studies of Phytochemical Compounds Present in Houttuynia cordata Thunb

   Thokchom Biona, Nameirakpam Bunindro Singh, Ojit Singh Keithellakpam, Sanjai Srinivasan, Shankarrao Patil, Pulok Kumar Mukherjee, Nanaocha Sharma

   pp. 870–881 · DOI: 10.5530/ijper.58.3.95 · 2024

   Aim The study aimed to identify the phytochemical constituents present in the leaves, stems, and roots of H. cordata and perform in silico molecular docking studies of selected common compounds present in all three parts…

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Editorial

1. Forum Article

   Editorial: Embracing Innovation and Advancement in Pharmaceutical Sciences

   pp. i–ii · DOI: 10.5530/ijper.58.3.i · 2024

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