Bio-Conjugated Metallic Complexes in Drug Design

ABSTRACT

Background This comprehensive review highlights the importance of bio-conjugated metallic complexes in drug design, particularly in the field of metallo-pharmaceutical science. The review emphasizes the need for biological relevance and the coordination of biomolecules or modified bio-compounds with metallic systems to maximize drug action and minimize toxicity. Materials and Methods The objective of this review is to discuss various diseases, which exemplify the potential of bio-conjugated metallic complexes as a promising approach for drug design. Results Utilizing physiologically active ligands in metal complexes has demonstrated improved antioxidant, antiviral, antitubercular and antitumor effects. Conclusion Bio conjugated systems have become a viable method for creating molecules with several uses that are good for human health. The development of metal-based imaging agents and drug delivery systems has increased due to the conjugation of metals with biologically active compounds.

KEYWORDS

• Bio-conjugation
• Metallic complexes
• Drug design
• Metallo-pharmaceutical science
• Antioxidants
• Chelate

Showing references and in-text citations exactly as published.

• DOI10.5530/ijper.20255296Copy

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