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Indian Journal of Pharmaceutical Education and ResearchNOW IN
Review

Insight into the Synthesis Approaches of Oxadiazole and its Derivatives, Focuses on their Pharmacological Activities

Sadhana Sharma1, Chandana Majee1★, Rupa Mazumder1, Avijit Mazumder1, Pankaj Kumar Taygi2, Sachin Kumar Singh3★★ Corresponding author

  1. 1Department of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), Greater Noida, Uttar Pradesh, INDIA.
  2. 2Department of Biotechnology, Noida Institute of Engineering and Technology, Greater Noida, Uttar Pradesh, INDIA.
  3. 3Department of Biotechnology, Lovely Professional University, Jalandhar-Delhi, Phagwara, Punjab, INDIA.

CORRESPONDENCE

Chandana Majee

Department of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), Knowledge Park 2, Greater Noida, Uttar Pradesh, INDIA.

cmchandana1@gmail.com

Received: 04-07-2024; Revised: 21-07-2024; Accepted: 22-08-2024.

Volume 59, Issue 1S · pp. a25–a45 · PUBLISHED Oct-Dec 2024 · DOI: 10.5530/ijper.20250270

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ABSTRACT

Oxadiazoles and their derivatives represent a significant class of organic compounds, wielding profound implications in both the realms of medicinal science and heterocyclic rings housing oxygen and nitrogen atoms, has garnered attention owing to their multifaceted. Pharmacological potential. The diverse array of biological activities exhibited by oxadiazole derivatives spans antimicrobial, anti-inflammatory, anti-cancer and anti-viral effects. Beyond medicinal applications, these compounds showcase utility in agriculture, with their herbicidal, insecticidal and fungicidal properties enabling their role as effective plant protection agents. Researchers have been focusing on the synthesis and exploration of these compounds for their potential in drug development. This review article is an in-depth exploration of diverse synthetic methodologies for oxadiazole and its derivatives while highlighting their associated pharmacological activities. It offers valuable insights into this class of compounds' versatile chemistry and potential therapeutic applications.

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    Sharma, S., Majee, C., Mazumder, R., Mazumder, A., Taygi, P. K., & Singh, S. K. (2024). Insight into the Synthesis Approaches of Oxadiazole and its Derivatives, Focuses on their Pharmacological Activities. Indian Journal of Pharmaceutical Education and Research, 59(1S), a25–a45. https://doi.org/10.5530/ijper.20250270