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Indian Journal of Pharmaceutical Education and ResearchNOW IN
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Mesoporous Silica Nanoparticles: A Promising Portal for Diagnosis and Treatment for Chronic Diseases

Saravanakumar Kasimedu1★, UshaPriya Halapaka Selvam1★, Keerthishree Suresh Sharma1★, Navina Sreenivasan Arrivur1★, Niranjan Babu Mudduluru1★★ Corresponding author

  1. 1Department of Pharmaceutics, Seven Hills College of Pharmacy, Venkatramapuram, Tirupati, Andhra Pradesh, INDIA.

CORRESPONDENCE

Saravanakumar Kasimedu

Department of Pharmaceutics, Seven Hills College of Pharmacy, Venkatramapuram, Tirupati, Andhra Pradesh, INDIA.

saravanakumar156@gmail.com

Received: 05-05-2024; Revised: 09-09-2024; Accepted: 22-02-2025.

Volume 59, Issue 3S · pp. s776–s787 · PUBLISHED Jul-Sep 2025 · DOI: 10.5530/ijper.20251674

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ABSTRACT

Nanotechnology is a promising technology in the creation of novel strategies in the field of the healthcare domain. Nano distribution of pharmaceuticals emerging new features for enhanced targeted drug delivery in the diagnosis of chronic disorders like cancer, AIDs and Alzheimer’s disease. Numerous types of nanocarriers were established in the Nanotechnology. Mesoporous Silica Nanoparticles (MSNs) are an inorganic form of nanoparticle having specific characteristics like tunable pore size, particle size, suitable morphology and surface functionalization. These attributes show effective loading of therapeutic agents, including micro molecules, genes, proteins and peptides through chemical bonding. Through improved bioavailability, controlled medication release, focused drug delivery and lesser adverse effects, mesoporous silica nanoparticles have largely advanced in the treatment of chronic illnesses. MSNs have many applications, especially in the medical field like Bioimaging, target specificity, pH stimuli response and Thernostatics, etc., Cancer is the most prevailing disease across the world, in various therapies were established using MSNs to increase the medicine's solubility and better delivery of the medication. By integrating poorly soluble medications into their hollow structure, MSNs increase their bioavailability. It allows for lower dosage forms and reduces adverse side effects.

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    Kasimedu, S., Selvam, U. H., Sharma, K. S., Arrivur, N. S., & Mudduluru, N. B. (2025). Mesoporous Silica Nanoparticles: A Promising Portal for Diagnosis and Treatment for Chronic Diseases. Indian Journal of Pharmaceutical Education and Research, 59(3S), s776–s787. https://doi.org/10.5530/ijper.20251674