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Indian Journal of Pharmaceutical Education and ResearchNOW IN
Review

A Comprehensive Review on Management of Insulin Resistance Disorder by Innovative Technologies and Advancement of Precision Medicinal Therapies

Aman Shrivastava1★, Sumeet Dwivedi2★, Shiv Narayan3★, Abhishek Dwivedi4★, Jailani Shiekmydeen5★, Amit Anand6★, Arvind Kumar Tripathi7★, Kuldeep Singh8★★ Corresponding author

  1. 1Department of Pharmacology, College of Pharmacy, Institute of Professional Studies, Gwalior, Madhya Pradesh, INDIA.
  2. 2Department of Pharmacognosy, Acropolis Institute of Pharmaceutical Education and Research, Indore, Madhya Pradesh, INDIA.
  3. 3Department of Pharmacology, Goel Institute of Pharmacy and Sciences, Lucknow, Uttar Pradesh, INDIA.
  4. 4Department of Pharmacognosy, Dr. Satyendra Kumar Memorial College of Pharmacy, RKDF University Bhopal, Madhya Pradesh, INDIA.
  5. 5Department of Formulation R&D, Alpha Pharma, KAEC, Rabigh, KINGDOM OF SAUDI ARABIA., Rabigh, SAUDI ARABIA.
  6. 6Department of Pharmacognosy JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, Karnataka, INDIA.
  7. 7Department of Biotechnology, A.P.S. University, Rewa, Madhya Pradesh, INDIA.
  8. 8Department of Pharmacology, Institute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, INDIA.

CORRESPONDENCE

Aman Shrivastava

Department of Pharmacology, College of Pharmacy, Institute of Professional Studies, Gwalior-474001, Madhya Pradesh, INDIA.

amanipsgwl@gmail.com

Received: 15-03-2025; Revised: 06-06-2025; Accepted: 04-04-2025.

Volume 59, Issue 3S · pp. s814–s824 · PUBLISHED Oct-Dec 2025 · DOI: 10.5530/ijper.20250849

View on IJPER original site ↗

ABSTRACT

The increasing prevalence of insulin resistance disorders, including type 2 diabetes and metabolic syndrome, underscores the urgent need for advanced diagnostic and therapeutic strategies. This review aims to explore the role of innovative precision medicine in revolutionizing the assessment and management of insulin resistance disorders. By integrating genetic, epigenetic and environmental data, precision medicine provides a more nuanced understanding of disease mechanisms and enables personalized treatment approaches. This review mainly highlights recent advancements in biomarker identification, novel therapeutic targets and individualized treatment regimens driven by precision medicine. We emphasize the importance of emerging technologies like genomics, metabolomics and digital health tools in enhancing diagnostic accuracy and therapeutic efficacy. The integration of these innovations promises to improve patient outcomes and offers a new paradigm in the management of insulin resistance disorders. By addressing the heterogeneous nature of insulin resistance disorders, precision medicine offers a promising avenue for more effective and efficient healthcare solutions. Despite the potential, challenges remain, including ethical considerations, high costs and the need for specialized training. The successful integration of precision medicine into routine clinical practice requires standardized protocols and improved infrastructure. Future research should address these challenges and focus on translating technological and scientific advancements into practical, equitable healthcare solutions. In conclusion, precision medicine offers a transformative approach to managing insulin resistance, with the potential to improve patient outcomes and advance our understanding of metabolic disorders.

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    Shrivastava, A., Dwivedi, S., Narayan, S., Dwivedi, A., Shiekmydeen, J., Anand, A., Tripathi, A. K., & Singh, K. (2025). A Comprehensive Review on Management of Insulin Resistance Disorder by Innovative Technologies and Advancement of Precision Medicinal Therapies. Indian Journal of Pharmaceutical Education and Research, 59(3S), s814–s824. https://doi.org/10.5530/ijper.20250849