Volume 11, Issue 2

Satish Arunrao Polshettiwar, Chinmay Devidas Deshmukh, Akshay Motilal Baheti, Manish Shivdas Wani, Ekta Bompilwar, Devashree Jambhekar, Shradha Choudhari, Amol Tagalpallewar

pp. 131–136 · DOI: 10.5530/ijpi.2021.2.25 · 2021

A biosensor provides a strategy for the detection of microbiological signals through various chemical, biological and physical technology and is an analytical, high-sensitivity rapid tool in pharmaceutical and health car…

SND Balakrishna Ch, Sai Pavan Dwarapudi, Ravi Kumar Reddy Juturi, Venkateswara Raju K.

pp. 137–142 · DOI: 10.5530/ijpi.2021.2.26 · 2021

Expedited approval processes push new drugs to the market faster than ever. Regulatory Authorities of the United States (US) and European Union (EU) are using different approval pathways to cut down the time it takes to …

B.M. Gupta, S.M. Dhawan, K.K. Mueen Ahmed, Ghouse Modin Mamdapur

pp. 143–153 · DOI: 10.5530/ijpi.2021.2.27 · 2021

The paper describes quantitative and qualitative dimensions of nanomedicine research studies in India. The study is based on research publications data in nanomedicine research (1491 publications) as covered in Scopus da…

Rosaline Mishra, Divya Juyal, Sadish Kumar Shanmugham

pp. 154–157 · DOI: 10.5530/ijpi.2021.2.28 · 2021

Objectives:It is well established fact that the phytochemicals with phenolic and flavonoids origin have antioxidant property. Thus in this study it was aimed to determine the in vitro antioxidant potential of various ext…

Satyanarayana Murthy Malladi, Nagendra Sastry Yarla, Devendra Kumar Pandey

pp. 158–164 · DOI: 10.5530/ijpi.2021.2.29 · 2021

Objectives: The present work was aimed to determine the effect on the Phospholipase A2 (PLA2) enzyme and conduct its antioxidant nature, phytochemical analyses of the Triphala compound’s extract, an Ayurvedic Rasayana ma…

Nidhi Gupta, Rakesh Sagar, Mohan Lal Kori

pp. 165–169 · DOI: 10.5530/ijpi.2021.2.30 · 2021

Background:Chenopodium botrys L. is local to Europe and Asia and established in North America. The plant commonly used for the treatment of disease. The medicinal use of Chenopodium botrys is mainly due to mythology rath…

Abdul Rouf Wani, Kanchan Yadav

pp. 170–175 · DOI: 10.5530/ijpi.2021.2.31 · 2021

Objectives:The main aim of this research was to evaluate phytochemicals, antimicrobial, antiproliferative and antioxidant Activities of the essential Oil of Monarda citriodora growing in Kashmir (India). Materials and Me…

Mallela Vijaya Jyothi, Nayakanti Devanna, Akkiraju Sudheer

pp. 176–183 · DOI: 10.5530/ijpi.2021.2.32 · 2021

Objectives:Atherosclerosis is caused by vascular inflammation and oxidative stress. Pro-atherogenic effect of hypercholesterolemia caused by impairment of nitric oxide generation due to activated arginase. The current st…

Ravindran Sumitha, Narasiman Banu, Swaminathan Vijayalakshmi, Venkatesan Krithika

pp. 184–188 · DOI: 10.5530/ijpi.2021.2.33 · 2021

Background:Ocean acts as a wealthy resource of biological diversity producing prospective novel metabolites from the organisms present in the environment. Novel bioactive compounds from Echinoderms mainly from sea stars …

Bhushan Dnyandeo Varpe, Shailaja Bhanudas Jadhav

pp. 189–194 · DOI: 10.5530/ijpi.2021.2.34 · 2021

Objectives:To synthesize Schiff base conjugate of 5-Fluoroisatin with thiophene-2-ethylamine and its Mannich bases and screen for anti-inflammatory and anti-tubercular activity. Materials and Methods:The compounds were s…

Mateti Ashok, Mohammed Habibuddin, Jukanti Raju

pp. 195–203 · DOI: 10.5530/ijpi.2021.2.35 · 2021

Background:Acyclovir (ACV) a 21-deoxy guanosine analogue effective against Herpes Simplex Virus (both type 1 and 2) and other viral diseases, mainly acts by inhibiting the viral DNA polymerase. The limited oral bioavaila…

Ekramul Haque, Mohd Aamir Bin Riyaz, Sriram Shankar, Saqib Hassan

pp. 204–207 · DOI: 10.5530/ijpi.2021.2.36 · 2021

Objectives:This study aimed to compositionally characterize the biosurfactant and its application in crude oil bioremediation. Methods:Production of biosurfactant was carried out in Bushnell Hass Broth (BHB), supplemente…

Sumanta Mondal, Sabyasachi Biswal, Trayambica Acharya, Prasenjit Mondal, Kausik Bhar

pp. 208–213 · DOI: 10.5530/ijpi.2021.2.37 · 2021

Objectives:The present article involved the development of sensitive and validated Ultraviolet (UV) Spectrophotometric and reverse phase liquid chromatographic and method for the determination of lapatinib in bulk and ph…

Ashish Kandalkar, Nitu Singh

pp. 214–219 · DOI: 10.5530/ijpi.2021.2.38 · 2021

Objectives: The objective of this study is to extract Phytochemical constituent from Cinnamon Bark and to design and develop the transdermal patch of the herbal drug along with modern medicine Glibenclamide using solvent…

Dilip Kumar Patel, Roohi Kesharwani, Vikas Kumar

pp. 220–224 · DOI: 10.5530/ijpi.2021.2.39 · 2021

Objectives:The present work focus on to create Solid lipid nanoparticles (SLN) and nanostructured lipid Carrier (NLC) as transporters for effective delivery of Etodolac (ETD). Methods:Etodolac stacked SLN and NLC were se…

Vishwajeet Swami, Amir A Shaikh, Pooja N Jadhav, Rahul S Buchade

pp. 225–229 · DOI: 10.5530/ijpi.2021.2.40 · 2021

Background:Microsponge is a class of dosage form containing porous nature containing drug that is targeted to achieve sustained action for prolong period. Microsponge based delivery system results in drug localization on…

Sindhoor Shridharan Mulleria, Koland Marina, Sawan Mukund Ghetia

pp. 230–237 · DOI: 10.5530/ijpi.2021.2.41 · 2021

Background:Psoriasis is an autoimmune-mediated disease characterized marked by thickened plaques and erythematous skin, which can be treated by topical delivery of apremilast. The objective of this study was to prepare h…

Sanjay Nipanikar, Narendra Mundhe, Vaishali Deshpande, Nitin Shinde, Mangesh Wakchaoure, Pravin Ghadge

pp. 238–243 · DOI: 10.5530/ijpi.2021.2.42 · 2021

Background:Aphthous stomatitis is a painful and often inflammatory condition. Objective of the study is to evaluate safety and efficacy of Arimu mouth ulcer gel (AHPL/ AYTOP/2014A) in subjects suffering from aphthous ulc…

Ruhul Amin, Biplab Kumar Dey, Suhaj Abdulsalim, Mohan K. Manu

pp. 244–247 · DOI: 10.5530/ijpi.2021.2.43 · 2021

Objectives:Extensive literature survey revealed that chronic obstructive pulmonary disease (COPD) is one of the primary burdens for low-income countries like India. Out of around 30 million COPD patients in India, a cons…