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International Journal of Pharmaceutical InvestigationNOW IN
Article

Standardization of Kirāmpu kutinīr Decoction and Extract Granules using Pharmacognostic, Physicochemical and HPTLC Studies

Brindha Sundaramoorthy1, Achintya Kumar Mandal2, Vinayak Soman3, Shree Devi Munusamy Sampangiramulu3★, Sunil Kumar Koppala Narayana1, Shakila Ramachandran2, Sathiyarajeswaran Parameswaran4, Kiruthiga Ganesan5★ Corresponding author

  1. 1Department of Pharmacognosy, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.
  2. 2Department of Chemistry, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.
  3. 3Department of Pharmacy, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.
  4. 4Director I/c, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.
  5. 5Central Council for Research in Siddha, Chennai, Tamil Nadu, INDIA.

CORRESPONDENCE

Shree Devi Munusamy Sampangiramulu

Department of Pharmacy, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.

shreemd@gmail.com

Received: 06-09-2021; Revised: 30-09-2021; Accepted: 25-10-2021.

Volume 11, Issue 4 · pp. 362–367 · PUBLISHED · DOI: 10.5530/ijpi.2021.4.65

View on IJPI original site ↗

ABSTRACT

Introduction:Siddha being one of the ancient systems of medicine, has been counted on by most of the population during the outbreak of pandemics in recent times. The decoctions like nilavempu kutinir and kapacura kutinir have been authorized for prescription for conditions like dengue, Covid-19 etc. Kirampu kutinir (KK) is one such decoctions which has been found efficacious in Covid patients with respiratory tract infections. The current study is aimed at standardizing KK curnam and two of its dosage forms like Kutinir and extract granule employing pharmacognostic and chemical analyses. Methods: Kirampu kutintr (KK) and Kirampu kutinir extract granules (KEG) were analysed for pharmacopoeial standards following standard procedures. Results: The macroscopy and powder microscopy correlated with standards and matched with their characters. Both HPTLC photo documentation and densitometric scan revealed that the KEG comprises of the said ingredients. It also divulges that KEG and KK are of same bands and same pattern. Conclusion: The reported results will be supportive for standardization and future studies of KK.

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    Sundaramoorthy, B., Mandal, A. K., Soman, V., Sampangiramulu, S. D. M., Narayana, S. K. K., Ramachandran, S., Parameswaran, S., & Ganesan, K. (). Standardization of Kirāmpu kutinīr Decoction and Extract Granules using Pharmacognostic, Physicochemical and HPTLC Studies. International Journal of Pharmaceutical Investigation, 11(4), 362–367. https://doi.org/10.5530/ijpi.2021.4.65