Volume 12, Issue 3

Utkarsh Ghate, Hema Kulkarni, Manasi Deshpande, Mandar Akkalkotkar

pp. 250–254 · DOI: 10.5530/ijpi.2022.3.45 · 2022

Molecular docking studies are used to identify cultivated/ abundant herbs such as Coriander, Burmuda grass or Asparagus as potential replacement for Seeta Ashoka- Saraca asoca (Roxb.) De Wilde, syn. S. indica Linn. a rar…

Raseema Raheema Sharafudeen, Annie Abraham, Reshma Usha Soman

pp. 255–259 · DOI: 10.5530/ijpi.2022.3.46 · 2022

Background: The coconut palm is so much more than just a tree; because all of this is essential with medicinal benefits. Coconut inflorescence sap (CIS) is the sweet, oyster-white colored, non-fermented juice tapped from…

Snigdha Bhardwaj, Pushpraj S Gupta

pp. 260–271 · DOI: 10.5530/ijpi.2022.3.47 · 2022

Background: Pseudomonas aeruginosa (P. aeruginosa) is considered as one of the most opportunistic pathogens that may infect humans and led to increase in bacterial virulence or pathogenicity. P. aeruginosa exhibits varie…

Anoop Kumar, Ashutosh Mishra

pp. 272–279 · DOI: 10.5530/ijpi.2022.3.48 · 2022

Background:The colon targeted drug delivery system is mainly useful for the topical treatment of colon diseases such as ulcerative colitis, Crohn’s disease OR colorectal cancers where we attain high local concentration a…

Rajasekhar Pinnamaneni, Udaya Sri Puttagunta

pp. 280–287 · DOI: 10.5530/ijpi.2022.3.49 · 2022

Background: Herbicides are classified either by toxicity or by mechanism of action, based on the chemical nature of the compound. Herbicides fall into two categories. Contact the herbicide and the transferred herbicide. …

Hina Bagada, Vishva Bhut, Himaxi Parmar

pp. 288–292 · DOI: 10.5530/ijpi.2022.3.50 · 2022

Background:Prochlorperazine maleate is an antipsychotic and antiemetic drug that is available as tablets on the market for oral administration. The main object of this research work is to develop and validate the easiest…

Ravisinh Vikramsinh Solanki, Ravi Bharatkumar Patel, Rajeshkumar Kanubhai Patel, Binal Manojkumar Patel

pp. 293–298 · DOI: 10.5530/ijpi.2022.3.51

Objectives:A selective, precise and accurate RP-HPLC stability indicating assay method has been developed for the simultaneous estimation of Azilsartan medoxomil and Cilnidipine in tablet dosage form. Materials and Metho…

Mandeep Kumar Singh, Umesh Kumar Patil

pp. 299–316 · DOI: 10.5530/ijpi.2022.3.52 · 2022

Objectives: The silymarin phytosome (SPY) was developed to improve the solubility and dissolution. The prepared phytosome was evaluated for hemolytic, membrane stabilization activity, and in vivo acute and subchronic tox…

Ashish Yashwantrao Pawar, Ashvini Dhanraj Tapkir, Jyoti Bramhesh Rao, Rushikesh Pramod Dayama

pp. 317–322 · DOI: 10.5530/ijpi.2022.3.53 · 2022

Background:The pharmaceutical industries are keen in development of new herbal bioactive molecules with an improved effect and less toxicity in order to replace synthetic drugs. Constipation is the most prevalent medical…

Manjunath Pobbathi Nagaraj, Avinash Kumar Seth, Anand Kandkere Ravindra Kumar, Vivekanandan Sundaramurthy

pp. 323–327 · DOI: 10.5530/ijpi.2022.3.54 · 2022

Background: Circadian rhythms is a natural process that regulates the sleep wake cycle which is associated with several physiological, biochemical, endocrine, behavioural processes in humans and entrainment to light-dark…

Anita Ricablanca, Ami Abbott, Fatimata Sonago, Montserrat Garcia, Rachel Primacio, Eric Patten, Mudassar Iqbal Arain, Eduardo Fricovsky

pp. 328–333 · DOI: 10.5530/ijpi.2022.3.55 · 2022

Background:These studies examined mutual protective relationships among rabbit muscle aldolase, enolase, phosphofructokinase-1 (PFK-1) and LDH from inhibitions by ascorbate (AA). It was proposed earlier that specific inh…

Patricia Gaitan-Hahn, Anita Ricablanca, Ami Abbott, Jessica Chadwick, Alicia Thomas, Nathalia Cruz, Alice Deng, Leah Ordinanza, Mudassar Iqbal Arain, Eduardo Fricovsky

pp. 334–339 · DOI: 10.5530/ijpi.2022.3.56 · 2022

Background: Previous studies suggested that glycogen storage was facilitated by ascorbate inhibition of phosphofructokinase-1 (PFK-1) in resting mammalian muscle; these studies showed that purified PFK-1 from fish or chi…

Shamli S Gupte, Arti Rathour, Divya Gupta, Richa Soni, Sadhana Shrivastava, Monika Bhaduria, Satendra Kumar Nirala, Shubham Singh, Anjali Sharma, Deepa Yadav, Samrat Rakshit, Sangeeta Shukla

pp. 340–345 · DOI: 10.5530/ijpi.2022.3.57 · 2022

Background: Tephrosia purpurea (TP), commonly known as wild indigo, is traditionally used in treatment of splenomegaly. It is an important ingredient of various Ayurvedic medicines used in treatment of liver diseases. Ob…

V. V. Rajesham, Ruqaiya Jabeen, Mitta Raghavendra, P. Roshan Ali, T. Rama Rao

pp. 346–350 · DOI: 10.5530/ijpi.2022.3.58 · 2022

Background:Renal disease is a significant issue of global proportions and renal damage is very prevalent as the kidney has the ability to excrete toxic substances to assess the protective impact of the Ethanolic extract …

Ranjana R, Deepak Kumar Singh, Bhaskar Laxman Jadhav

pp. 351–357 · DOI: 10.5530/ijpi.2022.3.59

Background: Diabetes mellitus is a metabolic disorder that causes millions of deaths throughout the world every year, and today also its incidence is on the increase. Many antidiabetic drugs are available in the pharmace…

Udaykumar Girdharlal Vegad, Devang Jagdishbhai Pandya

pp. 358–362 · DOI: 10.5530/ijpi.2022.3.60 · 2022

Background:Gojihva or Gaozaban, an Ayurvedic cum Unani Medicinal plant described with various properties, including diuretic activity. Onosma bracteata Wall. is considered the official species of Gojihva in Ayurveda and …

Arti Akash Bhimanwar, M M Ghaisas, R V Shete

pp. 363–369 · DOI: 10.5530/ijpi.2022.3.61 · 2022

Introduction:Huntington’s disease is considered as the autosomal dominating with progression of neuro-degeneration with decreased cognitive function and behaviour changes. Bioflavonoids promote memory, learning, and cogn…

Vikram Nimbalkar, Niraj Vyawahare

pp. 370–374 · DOI: 10.5530/ijpi.2022.3.62 · 2022

Background:The aim of the present study was to examine the protective potential of L-carnitine against Cisplatin-induced liver fibrosis in experimental models. Materials and Methods:The rats were randomly divided into fi…

Muhammad Irfan Bashir, Nur Hidayah Kaz Abdul Aziz, Dzul Azri Mohamed Noor

pp. 375–379 · 2022

Background: Monoamine oxidase-A (MAO-A) enzyme is responsible for the breakdown of monoamines (serotonin and norepinephrine). MAO-A is also a target to treat the depressive disorders. Kruppel-likefactor11(KLF11) and Sirt…

Sara Shahid, Fahad Ahmed, Amna Bajwa, Muhammad Ans, Anosh Sana, Sameen Abbas, Asma Fareed Khan, Aiman Mahmood, Qandeel Rafi, Shakeel Ahmad, Asifa Anwar, Rabeel Khan, Gul Shahnaz, Asad Majeed Khan

pp. 380–385 · DOI: 10.5530/ijpi.2022.3.64 · 2022

Introduction: Metered-dose inhalers are the most widely prescribed and dispensed inhaler devices worldwide for the management of asthma. The present study aimed to access the impact of educational intervention on the com…