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Review

The Phytochemical and Pharmacological Effects of Hibiscus rosa-sinensis: A Review

Ezza Izzati Zulkurnain1, Salfarina Ramli1,2, Aida Azlina Ali1, Richard Johari James1,2, Ihsan Safwan Kamarazaman1,3, Hasseri Halim1,2★★ Corresponding author

  1. 1Faculty of Pharmacy, Universiti Teknologi MARA Selangor, Puncak Alam Campus, 42300, Bandar Puncak Alam, Selangor, MALAYSIA.
  2. 2Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA Selangor, Puncak Alam Campus, 42300, Bandar Puncak Alam, Selangor, MALAYSIA.
  3. 3Natural Products Division, Forest Research Institute Malaysia (FRIM), 52109 Kepong, Selangor, MALAYSIA.

CORRESPONDENCE

Hasseri Halim

Faculty of Pharmacy, Universiti Teknologi MARA Selangor, Puncak Alam Campus, 42300, Bandar Puncak Alam, Selangor, MALAYSIA.

hasseri2945@uitm.edu.my

Received: 28-03-2023; Revised: 16-04-2023; Accepted: 01-05-2023.

Volume 13, Issue 3 · pp. 422–431 · PUBLISHED · DOI: 10.5530/ijpi.13.3.053

View on IJPI original site ↗

ABSTRACT

Medicinal plants play important roles in the treatment of various diseases. The aim of this review is to compile and document the phytochemical properties and the pharmacological effect in different parts of the various extracts of Hibiscus rosa-sinensis. The information was collected from various electronic databases such as Google Scholar, PubMed, Web of Science, Science Direct, Scifinder and articles published in English. Previous studies have revealed that the leaves of the plant contain important constituents such as tannins, saponins, glycosides, f lavonoids, and terpenoids, while the petals contain compounds such as quercetin, kaempferol, and anthocyanins. The chemical composition of the plant may vary depending on the color of the petals, with red petals having more anthocyanins and white petals having slightly higher levels of tannins. The anti-inflammatory, antioxidant, anti-microbial and anti-diabetic activity of Hibiscus rosa-sinensis have been documented. This review will contribute to a more organized f inding on the pharmacological effects of Hibiscus rosa sinensis and invigorate further studies.

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    Zulkurnain, E. I., Ramli, S., Ali, A. A., James, R. J., Kamarazaman, I. S., & Halim, H. (). The Phytochemical and Pharmacological Effects of Hibiscus rosa-sinensis: A Review. International Journal of Pharmaceutical Investigation, 13(3), 422–431. https://doi.org/10.5530/ijpi.13.3.053