Article

Challenges and Future Prospects: A Benefaction of Phytoconstituents on Molecular Targets Pertaining to Alzheimer's Disease

Himanshu Sharma1★, Phool Chandra1★ Corresponding author

  1. 1Department of Pharmacology, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, INDIA.

CORRESPONDENCE

Himanshu Sharma

Department of Pharmacology, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, INDIA.

amitsharmaaligarh786@gmail.com

Received: 15-07-2023; Revised: 09-10-2023; Accepted: 25-10-2023.

Volume 14, Issue 1 · pp. 117–126 · PUBLISHED · DOI: 10.5530/ijpi.14.1.15

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ABSTRACT

Background: Many parts of the brain experience excruciating pain as a result of Alzheimer's disease, a form of dementia. Cognitive processes and neuropsychiatric regulation are disrupted by the numerous neuropathologies that exist. The everyday activities, social and professional lives, and overall health of the individual are all substantially impacted by this ongoing deterioration. In this, we comprehend the advantages and practicality of phytoconstituents on the molecular targets of Alzheimer’s disease. Materials and Methods: In order to write this review study, we used internet databases of publications including PubMed, Science Direct, Google Scholar, and Scopus. Results:The use of pharmaceuticals has been a cornerstone in treating AD for a very long time. However, this strategy has numerous disadvantages. You must alter your treatment strategy now more than ever. Due to their advantages, which include decreased risk and negative effects from use, natural treatments made from plants are becoming increasingly widespread. The current situation study focuses on the anti-AD capabilities of phytoconstituents, sheds light on those currently engaged in clinical trials, and gathers data on their precise mechanisms of action in opposition to various neuropathologies associated with AD. Conclusion:The phytoconstituents will undoubtedly contribute to the development of novel, safer AD treatments that are superior to the currently existing pharmaceutical options, whether taken alone or in combination.

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    Sharma, H., & Chandra, P. (). Challenges and Future Prospects: A Benefaction of Phytoconstituents on Molecular Targets Pertaining to Alzheimer's Disease. International Journal of Pharmaceutical Investigation, 14(1), 117–126. https://doi.org/10.5530/ijpi.14.1.15