Volume 16, Issue 4

Neeta Rai, Poonam R Inamdar, Jisha joseph, Omkar Kokate, Ajinkya Mote, Shivanjali Tagade, Narendra Mukesh Vishwakarma, Aryan Mangesh Vishwakarma, Pooja Malviya, Anjita Singh Thakur, Viren Mandlecha, Piyush Jangid

pp. 1202–1209 · DOI: 10.5530/ijpi.20260093 · 2026

Diabetes mellitus is a chronic and multifaceted disorder representing a major global health concern. The two primary forms, Type 1 and Type 2 diabetes, differ in origin and progression yet share serious complications, in…

Mukesh Kumar Malik, Rekha Dhull, Raman Sureshkumar

pp. 1210–1215 · DOI: 10.5530/ijpi.20260134 · 2026

Regulatory agencies around the world now rely heavily on electronic submissions, which improve operational effectiveness and compliance. It is crucial to evaluate how developing economies, especially India, conform to st…

K Pavani Reddy, Katika Nizamuddin, Haranath Chinthaginjala, E Bhargav, Kavadi Kartikeya, Kothakota Kousar, Chennavaram Kurmila, Maddileti Repollu

pp. 1216–1230 · DOI: 10.5530/ijpi.20260148 · 2026

Therapeutic Drug Monitoring (TDM) serves as a crucial component of personalized medicine, allowing healthcare providers to tailor drug dosages according to individual pharmacokinetic and pharmacodynamic profiles, thereby…

Rajashree Shashidhar Masareddy, Archana Sidagouda Patil, Ankita Kashinath Patil, Ravikiran Ramachandra Kanabargi, Pooja Prakash Rayanade

pp. 1231–1243 · DOI: 10.5530/ijpi.20260179 · 2026

The sunscreen industry is a growing industry because of the increasing need for skin protection and increased awareness of the harmful effects of sunlight by the consumer. Day by day more effective sunscreen actives, nov…

Ritu Sapra, Maitry Suthar, Khushboo Arora, Aakansha Meval, Akanksha Patel, Niyati Shah

pp. 1244–1250 · DOI: 10.5530/ijpi.20260188 · 2026

Pharmaceutical microbiology is at a pivotal moment as emerging technologies, global health demands, and evolving regulatory expectations reshape the landscape of drug development and manufacturing. This field, which trad…

Sakshi Wankhede, Anil Pethe

pp. 1251–1261 · DOI: 10.5530/ijpi.20260195 · 2026

Smart implants represent an advanced class of biomedical devices integrating sensing systems, microelectronics and targeted drug release mechanisms. These technologies enable adaptive, real time drug delivery based on ph…

Balijepalli Murali Krishna, Chandra Sekhar Patro, Ch. Taraka Ramarao

pp. 1262–1272 · DOI: 10.5530/ijpi.20260224 · 2026

Gastroretentive Drug Delivery Systems (GRDDS) are designed to remain in the stomach for extended periods, releasing their drug payload in the gastric environment. These platforms are especially beneficial for drugs with …

Mohammed Tarique, Mohiuddin Khan Warsi, Mohd Imtiaz Nawaz, Osama Ali Almuzaini, Mahjabeen Rahmani, Mohammad Azhar Kamal

pp. 1273–1284 · DOI: 10.5530/ijpi.20260227 · 2026

This review examines key dimensions of leishmaniasis, including its epidemiology, transmission dynamics, treatment options, and the major challenges and opportunities for control particularly through integration with oth…

Mayur Rajeshwar Dandekar, Pankaj Mandpe, Swati Satalkar, Deepak Khobragade

pp. 1285–1299 · DOI: 10.5530/ijpi.20260231 · 2026

Risk assessment in pharmaceutical manufacturing has become an essential component of modern pharmaceutical operations due to increasing regulatory requirements, complex supply chains, and growing quality and safety conce…

M Sindhu Kumari, Fatima Sanjeri Dasankoppa, Hasanpasha N Sholapur, M Mahesh Yadav, M.A. Umarfarooq, Arunkumar Gundaiah Ramesh, Pratiksha Akki, Akshay Shamnewadi, Rakshitha N Hemadri, Vijayakumar Murugesan

pp. 1300–1311 · DOI: 10.5530/ijpi.20260018 · 2026

Wound healing is a complex and dynamic biological process that can be significantly impaired by infection, chronic inflammation, and underlying systemic conditions such as diabetes and vascular disorders. Conventional wo…

Lakshmi Prasanthi Nori, Brahmaiah Bonthagarala, Cherukuri Harsha Vardhan, K.Lalitha Sri N V Sai Lakshmi, Sarapenta Sravani, Gumpati Supriya, Venkateswara Raju Kalidindi

pp. 1312–1322 · DOI: 10.5530/ijpi.20260296 · 2026

The healthcare digitization changed the delivery of care to patients but also enhanced the exposure of medical devices to cyberattacks. The recalls of pacemakers and insulin pumps for being vulnerable to flaws underscore…

Sree Janardhanan Vaithiyanathan, Nisha Vijayan Thankam, Mathan Swami, Ganna Anitha

pp. 1323–1337 · DOI: 10.5530/ijpi.20260023 · 2026

Carbazoles and their partially saturated analogues, tetrahydrocarbazoles, have attracted considerable interest in medicinal chemistry owing to their broad spectrum of pharmacological activities and structural versatility…

Sakshi Wankhede, Anil Pethe

pp. 1338–1345 · DOI: 10.5530/ijpi.20260198 · 2026

Chronic pain is a major global health problem that reduces quality of life and strains healthcare systems. Conventional treatments often provide limited relief and cause side effects, highlighting the need for better the…

Lakshmi Prasanthi Nori, Nagineni Sudarshan Rao, Kiran Manda, M.S.Raghu Bapiraju, Yarra Priyanka, Boyina Lakshmi Venkata Maneesh, Addala Bhargavi Satya, Kondabolu Raghuram, K Venkateswara Raju

pp. 1346–1357 · DOI: 10.5530/ijpi.20260244 · 2026

Digital health is a paradigm shift in healthcare, and it makes the industry data-driven, efficient, and patient-centered in terms of care delivery. The Digital Age in the realms of clinical and administrative has opened …

Kaniga Pandi, Binoy Varghese Cheriyan, Nimithasree Keerthivasan, Mridula Dhanapal Saravanan, Dhanavarsha Govindaraj, Jai Anand Jagadeesan, Dinesh Kumar Eshwaravelu, Sam Helinto, Dharshini Jaisankar Hindumathi, Sowmiya Philip, Pradhosh Sakthivel, Rajeshkumar Thirupathi, Revathy Kumar

pp. 1358–1376 · DOI: 10.5530/ijpi.20260187 · 2026

Drug resistance continues to be a major barrier to the successful treatment of Oral Squamous Cell Carcinoma (OSCC). Numerous processes, including the upregulation of efflux transporters, alterations in drug metabolism, a…

Sree Janardhanan Vaithiyanathan, Nandini Goudar

pp. 1377–1383 · DOI: 10.5530/ijpi.20260005 · 2026

Hydrochlorothiazide (HCTZ) is one of the most widely prescribed thiazide diuretics which is frequently formulated in fixed-dose combinations with angiotensin II receptor blockers, Angiotensin Converting Enzyme (ACE) inhi…

Abubakar Mohamedali Omer Idress, Amgad Gamal Abdulrahman Abbas, R. Shirisha, K. Venkata Janardhanreddy, M. Rizwana, Nawaz Mahammed

pp. 1384–1395 · DOI: 10.5530/ijpi.20260162 · 2026

Additive manufacturing (also referred to as 3D printing, 3DP) has become a disruptive technology in the pharmaceutics industry, providing an opportunity to produce individualized and custom dosage forms on demand. In con…

Sagar Mathad, Hasanpasha N Sholapur, Fatima Sanjeri Dasankoppa, Arunkumar Gundaiah Ramesh, Kamaladevi Kshatriya, Shreya Ajay Prabhu, Vijaykumar Meti, ST Bhagawati, Vijayakumar Murugesan

pp. 1396–1409 · DOI: 10.5530/ijpi.20260255 · 2026

Wound healing, particularly in chronic and infected wounds, remains a major clinical challenge due to delayed tissue repair, poor oxygenation and rising antimicrobial resistance. Ozonated oils have emerged as promising t…

Ramasamy Devendran Dhanushya, Ramaiyan Velmurugan, James Jemimah Smileyn, Rangadurai Pavithra, Babu Krishnapriya, Ravichandran Praveen

pp. 1410–1416 · DOI: 10.5530/ijpi.20260043 · 2026

Background Complementary Alternative Medicine (CAMs) was extensively Utilized across countries for managing chronic and acute condition, with practices including Acupuncture, Ayurvedic, meditation, chiropractic, naturopa…

Yukio Kadokawa, Akitoshi Tatsumi, Fukunori Kawahara, Saki Tanaka, Hiroki Osako, Satoshi Hasegawa, Kenji Takeda, Mari Takagi

pp. 1417–1423 · DOI: 10.5530/ijpi.20260121 · 2026

Background Hyperglycemia frequently occurs during clinical administration of Everolimus (EVL). We investigated hyperglycemia occurrence after EVL administration in 52 Japanese patients with breast cancer, the treatment c…