Volume 17, Issue 1

Gogula Priya, Chinthaginjala Haranath, Donnepati Pradeep Sai, Konda Sai Megha, Sugur Samhitha, Vallapureddy Vasanthi, Kopparapu Maddi Venkata Ramu, Talapula Santhosh Kumar, Lingadahalli Bilwa Malini, Kotra Mounika

pp. 1–8 · DOI: 10.5530/ijpi.20270203 · 2026

Cannabis sativa is the primary source of phytocannabinoids, which are meroterpenoids with a resorcinol core that are also present in other plant species such as Helichrysum and Echinacea. There are over more than 100 phy…

Kaniga Pandi, Binoy Varghese Cheriyan, Kumaraguru, Bhavya Ekambaram, Arunpandiyan Jeyakumar, Inigo Pathuvairajan, Jai Anand Jagadeesan, Dinesh Kumar Eshwaravelu, Pradhosh Sakthivel, Rajeshkumar Thirupathi

pp. 9–20 · DOI: 10.5530/ijpi.20270069 · 2026

Rabies remains a fatal zoonotic disease and a significant public health concern, particularly in underdeveloped countries. Although effective vaccines exist, early diagnosis and timely intervention are limited due to the…

Brahmaiah Bonthagarala, Sirisha Arige, Gadamsetti Naga Sai AnupamaSri, Mathi Queeny Hadassa, Chekuri Jahnavi, Choppala Jhaneesha, Kandukuri Sri Venkata Lakshmi, Kasilinka Kavya Sri, Rama Rao Vadapalli

pp. 21–29 · DOI: 10.5530/ijpi.20270233 · 2026

Breast cancer remains a ubiquitous malignancy affecting women across the world, especially in aggressive subtypes like triple-negative breast cancer and HER2-positive tumors. Although conventional modalities like chemoth…

Kaniga Pandi, Binoy Varghese Cheriyan, Sudharshini Srinivasan, Praveen Kumar Ramesh, Bhuvanesh Raj, Preethi Harikrishnan, Sharmila Sakthisivanandhan, Jubilee Ramsamy, Yokesh Shanmugam, Maha Swetha Kannuchamy, Arunpandiyan Jeyakumar, Inigo Pathuvairajan, Mathesvaran Thirunavukarasu

pp. 30–50 · DOI: 10.5530/ijpi.20270285 · 2027

Bone remodeling is a tightly regulated physiological process governed by the coordinated activities of bone-forming osteoblasts and bone-resorbing osteoclasts. Emerging evidence highlights the immune system as a critical…

Madhavi Nimmathota, Billa Sravani, Medapatla Hari Priya, Uma Maheshwara Rao Vattikuti

pp. 51–62 · DOI: 10.5530/ijpi.20270001 · 2026

Non-invasive nasal drug delivery systems have emerged as a promising route for drug administration. It facilitates rapid therapeutic effect, bypass first pass metabolism, increase patient compliance and provides nose-to-…

Chitrali Talele, Dipali Talele, Yogita Shinde, Archana Shaha, Niyati Shah, Chintan Aundhia

pp. 63–76 · DOI: 10.5530/ijpi.20270046 · 2026

Mucosal drug delivery has emerged as a promising strategy for both local and systemic therapeutic administration due to its non-invasive nature and extensive absorptive surface area. However, the protective mucus barrier…

Vandhana Vijayakumar, Thirumalaikumaran Rathinam, Subathra Sundar, Maheswari Murugan, Tarunika Balaji, Aswini Sreenivasan

pp. 77–85 · DOI: 10.5530/ijpi.20270070 · 2026

Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine illnesses affecting women of reproductive age. It is distinguished by hyperandrogenism, ovulatory failure, and polycystic ovarian morphology. The syndr…

Kamalesh Dilip Mali, Sachin Yadav, Arya Nilesh Dubey, Gaurav Bharat Deore

pp. 86–103 · DOI: 10.5530/ijpi.20270097 · 2026

Poor aqueous solubility remains a critical challenge in pharmaceutical development, leading to limited drug absorption, high variability in systemic exposure, and reduced therapeutic efficiency. Conventional approaches s…

Gorinkala Bhargavi Sudeeshna, M Mohan Varma, K.T. Sunil Kumar, Arumalla Sai Joshitha, Sujitha Pithani, Kesanapalli Uma Venkata Subba Prabha, Maitreya Paramkusam, Sudarshan Rao Nagineni

pp. 104–114 · DOI: 10.5530/ijpi.20270098 · 2026

Personalized Medicine (PM) represents a paradigm shift from the traditional “one-size-fits-all” approach to personalized preventive, diagnostic, and treatment regimens tailored to individual genetic, biological, environm…

A Ashvil, Diya Kiran, Lenora Katherine Crasto, C G Deepak, Mariyammathul Afeeza, Bipin Shaji, Shivaprasad Sirimalla, Allen Pinto, Uday Venkat Mateti, Shrinivasa Undaru Bhat, Juno Jerold Joel

pp. 115–120 · DOI: 10.5530/ijpi.20270111 · 2026

Although pharmacotherapy is a cornerstone in effectively managing mood fluctuations in bipolar disorder, adherence to prescribed medications often remains a challenge in the long run, to prevent recurrent episodes and ho…

Amit Anand, Aparna Inamdar, Bannimath Gurupadayya, Kushala Reddy, Mansi Sharma, Mohit Sharma, Arindam Kolay, Dipayan Rath, Romi Kumari Thakur, Himanshu Sharma

pp. 121–137 · DOI: 10.5530/ijpi.20270136 · 2026

Skin cancer remains one of the most prevalent malignancies worldwide, and delayed diagnosis often leads to poor clinical outcomes. Recent advances in Artificial Intelligence (AI), particularly deep learning and computer …

NS Preetham, Sarath Mundra, M Shreeja, R Gagan, Gayathri Karnam, Akhilesh Dubey

pp. 138–149 · DOI: 10.5530/ijpi.20270139 · 2027

Regulatory agencies have developed expedited drug approval pathways to accelerate patient access to therapies addressing unmet medical needs, particularly in oncology and rare diseases. The European Medicines Agency (EMA…

Preet Tyagi, Satyam Rajput, Khushi Shrivastava, Sakshi Chaudhary, Aditya Vikram Jain, Preeti Yadav

pp. 150–154 · DOI: 10.5530/ijpi.20270180 · 2027

Flame photometry is a sensitive technique for estimating alkali metals in pharmaceuticals and herbal extracts. It works on thermal excitation in a flame, causing desolvation, atomization, dissociation, and emission of li…

Mohammed Arfath Mysore Ismail, Lokesh Panjini Gopal Krishna, Muhammed Nufaiz Khalid, Akhilesh Dubey, Manohar Mahadev

pp. 155–167 · DOI: 10.5530/ijpi.20270226 · 2027

Phytosome technology has transformed the delivery of plant-based bioactives by effectively addressing issues such as poor solubility, instability, and limited oral absorption. Unlike traditional lipid carriers, phytosome…

Harini Vinayagam, Ritikasri Venkatraju, Sneha Raja, Jayasutha Jayram, Sujatha Kuppusamy, Divya Varshini Natarajan, Rajeswari Jagadeesan, Janeviennygrace, Roshini Nivetha, Sudharshan Antony Raj, Nandhakumar Kannan, Sruthika Natarajan

pp. 168–176 · DOI: 10.5530/ijpi.20270199 · 2027

Polycystic Ovarian Syndrome (PCOS) is a common endocrine disorder in women of reproductive age, with insulin resistance and hyperinsulinemia playing key roles in its development. Although metformin is widely used to impr…

Yang Yang, Tiefeng Jin, Xiangshan Ren, Junjie Piao, Xianchun Zhou, Aihua Jin, Songnan Zhang, Zhenhua Lin

pp. 177–188 · DOI: 10.5530/ijpi.20270231 · 2027

In the context of rapid transformations in healthcare systems and medical knowledge, contemporary medical education faces increasing demands to cultivate physicians who are not only clinically competent but also innovati…

Yokesh Shanmugam, Sambasivam Gopinath, Bhagyashree Annadurai, Saroj Kumari Sanjay Kumar, Dharshini Jaisankar Hindumathi, Ramya Govindarajulu, Sam Jebaraj, Dravid Raghul, Aswini Sreenivasan, Maha Vidya Gnanamani, R Abdur Rahman, Kaniga Pandi

pp. 189–206 · DOI: 10.5530/ijpi.20270252 · 2027

Proteolysis-Targeting Chimeras (PROTACs) have revolutionized small-molecule pharmacology by harnessing the ubiquitin-proteasome system to achieve catalytic, event-driven degradation of disease-associated proteins rather …

Hamza Kutty Pottengal, Prasanth Viswanadhan Vasantha, Rakeshkumar Jat

pp. 207–214 · DOI: 10.5530/ijpi.20260006 · 2026

Background: The innovative analytical quantification of lupus medication Voclosporin was developed by HPLC, and HPTLC was abetted by the Ultra Violet spectroscopic method using the QbD approach. Materials and Methods: Th…

Mehdi Fathima, Deepak Kumar Jha, Saroj Kumar Sah, Soham Bhattacharjee

pp. 215–223 · DOI: 10.5530/ijpi.20270254 · 2026

Aim and Objectives: Around 20% of diabetic patients are at increased risk of chronic foot ulcers. Current treatments mainly focus on glycemic control and supportive care, with limited effectiveness. Mononuclear Cell (MNC…

Shaik Parveena Ferdhoz, Naga Srinivasa Reddy Durgempudi, Pavan Kumar Yanamadala, Ramya Athina, Hima Varshini Korrapati, Harish Kakani, Jyothika Mandava, Triveni Yeddu, Anjali Chokka, Rama Rao Nadendla, Pallavi Vadlamudi

pp. 224–231 · DOI: 10.5530/ijpi.20270256 · 2026

Background: Non-Communicable Diseases (NCDs) are increasingly driven by lifestyle and occupational factors, particularly in academic environments where staff experience varying workloads, sedentary patterns, and role-spe…