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International Journal of Pharmaceutical InvestigationNOW IN
Article

Eugenol significantly affects the flow of its nanodroplet gel

Kannissery Pramod1, Salim Shanavas2, Shahid H. Ansari3, Javed Ali1★★ Corresponding author

  1. 1Departments of Pharmaceutics.
  2. 2Starch Characterization Laboratory, Division of Crop Utilization, Central Tuber Crops Research Institute, Sreekariyam, Thiruvananthapuram, Kerala, INDIA.
  3. 3Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard, Hamdard Nagar, New Delhi, INDIA.

CORRESPONDENCE

Javed Ali

Departments of Pharmaceutics .

javedaali@yahoo.com

Volume 5, Issue 4 · pp. 200–204 · PUBLISHED · DOI: 10.4103/2230-973X.167669

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ABSTRACT

Introduction:Development of novel biomaterials for drug delivery which forms a part of the so called novel drug delivery systems has always been exhilarating. Mechanical evaluation of polymer based topical gels, which would be subjected to load or stress during its application, is inevitable. Methods: Rheological characterization was done by studying viscosity and yielding. Rheological modeling was also carried out. Results: The viscosity and yield stress were inversely dependent on the eugenol concentration. The gels followed Herschel–Bulkley and Bingham rheological models. Conclusion: Nanodroplets are colloidal systems and the microstructural changes in the Carbopol based nanodroplet gels were unveiled using rheometry.

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    Pramod, K., Shanavas, S., Ansari, S. H., & Ali, J. (). Eugenol significantly affects the flow of its nanodroplet gel. International Journal of Pharmaceutical Investigation, 5(4), 200–204. https://doi.org/10.4103/2230-973X.167669