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International Journal of Pharmaceutical InvestigationNOW IN
International Journal of Pharmaceutical Investigation volume 11, issue 1 cover
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Cover: International Journal of Pharmaceutical Investigation

International Journal of Pharmaceutical Investigation

Volume 11, Issue 1

· pp. 1–130 · 24 articles

Volume
11
Issue
1
Published
Pages
1–130
Articles
24
Sections
3
ISSN
Print - 2230-973X, Online -2230-9713
Journal
IJPI
Review ArticleOriginal ArticleShort Communication

In this issue

Review Article

  1. Review

    Phytochemicals Present in Cajanus cajan and its Use in Green Synthesis of Metal and Metal Oxide Nanoparticles

    Shriniwas Pramod Patil, Rajesh Yadav Chaudhari

    pp. 1–4 · DOI: 10.5530/ijpi.2021.1.1 · Published

    Many attempts have been made for green synthesis of metal oxide nanoparticles; revealing the importance of plant extracts in reducing metal/ metal oxide precursor to nanoparticles and their applications in various scient…

  2. Review

    Nanodrug Delivery Systems in Periodontics

    Pradeep Kumar Yadalam, Deepavalli Arumuganainar, Rajapandian Kasipandian, Kalaivani Varatharajan

    pp. 5–9 · DOI: 10.5530/ijpi.2021.1.2 · Published

    Nanotechnology is of intense interest to researchers due to the basic fact that the properties of the material can be effectively manipulated when the size is transformed to nanoscopic. New opportunities arise out of the…

Original Article

  1. Article

    Application of Green Silver Nanoparticles Synthesized using Leaf Extract of Tridax procumbens for Preparation of Clinical Antimicrobial Bandages

    Vitthal Chopade, Diksha Kamble

    pp. 10–13 · DOI: 10.5530/ijpi.2021.1.3 · Published

    Objectives:To green synthesize silver nanoparticles by using weed plant Tridax procumbens also prepare and check antimicrobial activity of silver nanoparticles impregnated bandages against one gram positive bacteria and …

  2. Article

    4-Aminoantipyrine Analogs as Anti-inflammatory and Antioxidant agents: Synthesis, Biological Evaluation and Molecular Docking Studies

    Qazi Yasar, Zahid Zaheer

    pp. 14–22 · DOI: 10.5530/ijpi.2021.1.4 · Published

    Objectives:A novel series of 4-aminoantipyrine derivatives were designed and efficiently synthesized from Gewald, triphosgene and various substituted aromatic/ aliphatic/heterocyclic amines. Methods:The synthesized deriv…

  3. Article

    Effects of Operational Parameters on the Removal of Tetracycline from Aqueous Solutions by Electrocoagulation

    Hossein Moein, Davoud Balarak, Ali Meshkinain, Kethineni Chandrika, Nastaran Yazdani

    pp. 23–26 · DOI: 10.5530/ijpi.2021.1.5 · Published

    Objectives:In this research, the efficiency of the Electrocoagulation (EC) process with aluminum electrodes in the removal of Tetracycline (TC) from synthetic solutions was studied. Methods:This study experimentally was …

  4. Article

    Influence of the Home Cooking Practices on the Bioactive Components of Two Important Edible Herbs- Amaranthus viridis and Amaranthus tricolor

    Debleena Roy, Renia Mullick, Namrata Chakraborty, Jayeesha Ghosh, Debapriya Das, Bidisha Mallick, Dipu Samanta

    pp. 27–31 · DOI: 10.5530/ijpi.2021.1.6 · Published

    Background:Antioxidants are substances that delays or inhibits the oxidation of a substrate by countering highly unstable entities (ROS and free radicals) that can cause cellular damage. Some natural source of antioxidan…

  5. Article

    Important Insight of Hypothetical Proteins from E. faecium Strain 13-022, the Drug Targeted Virulent Big-1 Adhesins: An in-silico Approach

    Brindangnanam Pownraj, Meenatchi Ramu, Ekramul Haque

    pp. 32–40 · DOI: 10.5530/ijpi.2021.1.7 · Published

    Background: Enterococcus faecium is an emerging multidrug resistant opportunistic pathogen responsible for causing most of the nosocomial infections. Adhesins are the cell wall anchoring proteins implicated in the pathog…

  6. Article

    Thermodynamic Study of Amoxicillin and Naphthalene Adsorption on Activated Carbon Derived from Salvadora persica

    Fredos Kord Mostafapour, Shaziya Haseeb, Davoud Balarak, Hossein Moein, Ali Akbar Sajadi, Zeynab Jalalzaei

    pp. 41–45 · DOI: 10.5530/ijpi.2021.1.8 · Published

    Objectives:The pollution of aquatic bodies by Naphthalene and antibiotics effluent from activities of many industry is a significant environmental challenge affecting the ecosystem. Batch process was used to remove Napht…

  7. Article

    From Biowastes to Potent Anticancer Leads Evaluation from Peel of Zingiber officinale Linn.

    Shaileyee Das, Subhash C Mandal

    pp. 46–51 · DOI: 10.5530/ijpi.2021.1.9 · Published

    Objectives:Zingiber officinale Linn. is a rhizome commonly consumed as a culinary purpose, medicine or spice in India. The aim of this study was to evaluate potent anticancer leads from ginger rhizome peel. Methods:Cytot…

  8. Article

    Validated HPTLC Method to Estimate Silymarin in Marketed Herbal Formulation

    Sharada L Deore, Hrutuja P Tidke, Somshekhar S Khadabadi, Bhushan A Baviskar, Anajli A Kide, Bhavna P Shende

    pp. 52–55 · DOI: 10.5530/ijpi.2021.1.10 · Published

    Objectives:The objective of present research work is to develop simple, rapid and accurate high performance thin layer chromatographic method for quantitative estimation of silymarin in marketed hepatoprotective formulat…

  9. Article

    Formulation and Evaluation of Topical Proniosomal Gel of Ciclopirox for Antifungal Therapy

    Suvarnalata Suhas Mahajan, RY Chaudhari, VR Patil

    pp. 56–62 · DOI: 10.5530/ijpi.2021.1.11 · Published

    Objectives:The objective of existent effort was topical proniosomal gel formulation and evaluation from the proniosomes of Ciclopirox to improve poor skin penetration and residence of the topical antifungal drugs. Method…

  10. Article

    Development and Evaluation of Acyclovir Loaded Poly Lactic-Co-Glycolic Acid Nanoparticles for Ocular Drug Delivery

    Harshal Dilip Mahajan, Rajendra Dayaram Wagh, Dheeraj Tukaram Baviskar

    pp. 63–68 · DOI: 10.5530/ijpi.2021.1.12 · Published

    Objectives:The objective of present study aim towards promising potential of acyclovir containing Poly Lactic-Co-Glycolic Acid based nanoparticles for delivering drug to ocular cavity and could be view as alternative to …

  11. Article

    Development and Characterization of Fast Dissolving Buccal Strip of Frovatriptan Succinate Monoydrate for Buccal Delivery

    Pankaj Bhatt, Suruchi Singh, Satish Kumar Sharma, Sani Rabiu

    pp. 69–75 · DOI: 10.5530/ijpi.2021.1.13 · Published

    Objectives:Aim of the present research work is to prepared fast mouth dissolving film of frovatriptan succinate monoydrate. Methods:Fast dissolving buccal film is prepared by Solvent casting method, hydroxypropyl methylc…

  12. Article

    Nanoparticles Containing Gel Formulation for the Treatment of Psoriasis

    Ramila Prajapati, Jayvadan Patel, Anita Patel

    pp. 76–81 · DOI: 10.5530/ijpi.2021.1.14 · Published

    Background:Psoriasis is a widespread chronic disease affecting 1-3% of total population and in most cases, treated by topical application of corticosteroids. Though, the topical route is very demanding because of the phy…

  13. Article

    Advanced Development of Carboxylic Acid Functionalized Multiwall Carbon Nanotubes as Safe Inhalation Drug Carrier

    Krishnat Dhekale, Sharvil Patil, Ravindra Kamble

    pp. 82–87 · DOI: 10.5530/ijpi.2021.1.15 · Published

    Background:Multiwall Carbon Nanotubes (MWCNTs) have innovative characteristic features strongly associated with nanotechnology and drug delivery applications. Objectives: The current work was performed with an objective …

  14. Article

    Cloning and Expression of Vacuolating Cytotoxin A (VacA) Antigenic Protein in Nicotiana benthamiana Leaves a Potential Source of the Vaccine against Helicobacter pylori

    Rambod Barzigar, Nanjundappa Haraprasad, Basaralu Yadurappa Sathish Kumar, Mohammad Javad Mehran

    pp. 88–93 · DOI: 10.5530/ijpi.2021.1.16 · Published

    Background: The applications of transgenic plants in the healthcare system are immense. They offer an alternative strategy for the fabrication of antigenic determinants of medically important pathogens. Objectives:Clonin…

  15. Article

    Role of p38 MAP Kinase Inhibitor (SB239063) and Vitamin B12 against Neuroinflammation

    Ashish Kumar Verma, Mamta Farswan Singh, Akanksha Awasthi

    pp. 94–98 · DOI: 10.5530/ijpi.2021.1.17 · Published

    Background:The objective of this work were to study the effect of p38 MAP Kinase inhibitor (SB239063) and Vitamin (Vit) B12 on activity of p38 MAP kinase implicated in neuroinflammation. “In the central nervous system (C…

  16. Article

    Neuroprotective Effect of p38 MAPKs Inhibitor (SB239063) and Vitamin B12 against Lipopolysaccharide Induced Neuroinflammation

    Ashish Kumar Verma, Mamta Farswan Singh, Akanksha Awasthi

    pp. 99–103 · DOI: 10.5530/ijpi.2021.1.18 · Published

    Objectives:To evaluate the effect of MAP kinase inhibitor (SB239063) on neuroinflammation along with Vitamin B12. Materials and Methods: Male wistar albino rats divided in to eight groups each group having six animals. N…

  17. Article

    Assessment of Acetylcholinesterase Inhibition and Anti-inflammatory Activity of Ethanolic Extract of Evolvulus alsinoides Linn.

    Garima Jain, Umesh Kumar Patil

    pp. 104–107 · DOI: 10.5530/ijpi.2021.1.19 · Published

    Objectives: The objective of present study is to determine the efficacy of ethanolic extract of Evolvulus alsinoides Linn. for therapeutics at various doses. One more purpose is also to determine anti-inflammatory effect…

  18. Article

    Effect of Co-administration Rotenone and Crocin on Biochemical and Histopathological Changes in Rat᾽s Kidney

    Amin Maghamifar, Hossein Najafzadehvarzi, Seyedmohammad Hossaini

    pp. 108–112 · DOI: 10.5530/ijpi.2021.1.20 · Published

    Background: Rotenone is one of the most widely used pesticides in agriculture and may affect public health through the food chain. A possible mechanism of rotenone toxicity is oxidative stress. This study, the supportive…

  19. Article

    Detection of Extended Spectrum Beta Lactamases (ESBLs) Producing Enterobacteriaceae Family from Urinary Tract Infection (UTI) Patients

    Devipalanisamy D, Sivapriya Olaganathan, Moorthy Marimuthu

    pp. 113–117 · DOI: 10.5530/ijpi.2021.1.21 · Published

    Background: Extended spectrum beta lactamase (ESBLs) are betalactamase capable of conferring bacterial resistance to the first, second and third-generation Cephalosporin’s but these are inhibited by lactamase inhibitors …

  20. Article

    Role of Omega-3 Fatty Acid in Childbearing Age Women with Vitamin D Deficiency in Sana’a City

    Doa’a Anwar Ibrahim, Rawya Shehab, Molok Saleh, Shyma’a Ali, Kawther Al-Hamati, Abdulsalam Halboup

    pp. 118–122 · DOI: 10.5530/ijpi.2021.1.22 · Published

    Background:The optimal intake of nutrients is a new approach to deriving nutrient requirements. Omega-3 is one of these nutrients that has a crucial role in body health. It can modulate inflammation, hyperlipidemia, plat…

  21. Article

    Knowledge and Attitude of Pharmacists about Biosimilar Medications in Saudi Arabia

    Abdullah Khaloofah Alahmari, Ziyad Saeed Almalki, Muhammad Shahid Iqbal, Manal Abdullah Alossaimi, Mohammed Zaid Alsaber, Raslan Abdullah Alanazi, Yazeed Mohammed Alruwaili, Saad Nashmi Altheiby, Thekra Omar Bin Salman

    pp. 123–126 · DOI: 10.5530/ijpi.2021.1.23 · Published

    Objectives:This study determined knowledge and attitude of pharmacists about biosimilar mdications in Saudi Arabia. Methods:Pharmacists from different areas and regions were approached to participate in this cross-sectio…

Short Communication

  1. Communication

    In vitro Cytotoxic and Antioxidant Activities of Careya arborea Root Extracts

    Bandenawaz Ramdurga, Rakesh Kumar Jat, Shrishailappa Badami

    pp. 127–130 · DOI: 10.5530/ijpi.2021.1.24 · Published

    Background:Careya arborea stem bark extracts were reported earlier by one of us to possess cytotoxic, antioxidant and anticancer properties. Since, the root of the plant has not been studied biologically so far, the pres…