Volume 11, Issue 2

· pp. 131–247 · 19 articles

Volume: 11
Issue: 2
Published
Pages: 131–247
Articles: 19
Sections: 3
ISSN: Print - 2230-973X, Online -2230-9713
Journal: IJPI

Review Article Meta Analysis Original Article

In this issue

Review Article

Review
Recent Trends on Biosensors in Healthcare and Pharmaceuticals: An Overview
Satish Arunrao Polshettiwar, Chinmay Devidas Deshmukh, Akshay Motilal Baheti, Manish Shivdas Wani, Ekta Bompilwar, Devashree Jambhekar, Shradha Choudhari, Amol Tagalpallewar
pp. 131–136 · DOI: 10.5530/ijpi.2021.2.25 · Published
A biosensor provides a strategy for the detection of microbiological signals through various chemical, biological and physical technology and is an analytical, high-sensitivity rapid tool in pharmaceutical and health car…
Review
Expedited Drug Review Processes for Approval in the United States and European Union with an Illustration
SND Balakrishna Ch, Sai Pavan Dwarapudi, Ravi Kumar Reddy Juturi, Venkateswara Raju K.
pp. 137–142 · DOI: 10.5530/ijpi.2021.2.26 · Published
Expedited approval processes push new drugs to the market faster than ever. Regulatory Authorities of the United States (US) and European Union (EU) are using different approval pathways to cut down the time it takes to …

Meta Analysis

Article
Nanomedicine Research in India: A Bibliometric Assessment of Publications Output during 2002-20
B.M. Gupta, S.M. Dhawan, K.K. Mueen Ahmed, Ghouse Modin Mamdapur
pp. 143–153 · DOI: 10.5530/ijpi.2021.2.27 · Published
The paper describes quantitative and qualitative dimensions of nanomedicine research studies in India. The study is based on research publications data in nanomedicine research (1491 publications) as covered in Scopus da…

Original Article

Article
Assessment of Antioxidant and Pancreatic Lipase Activity of Smilax zeylanica Roots: An in vitro Analysis
Rosaline Mishra, Divya Juyal, Sadish Kumar Shanmugham
pp. 154–157 · DOI: 10.5530/ijpi.2021.2.28 · Published
Objectives:It is well established fact that the phytochemicals with phenolic and flavonoids origin have antioxidant property. Thus in this study it was aimed to determine the in vitro antioxidant potential of various ext…
Article
Enzyme Inhibition Activity Both in vitro and in silico Screening of Triphala Plant Extracts on Phospholipase A2
Satyanarayana Murthy Malladi, Nagendra Sastry Yarla, Devendra Kumar Pandey
pp. 158–164 · DOI: 10.5530/ijpi.2021.2.29 · Published
Objectives: The present work was aimed to determine the effect on the Phospholipase A2 (PLA2) enzyme and conduct its antioxidant nature, phytochemical analyses of the Triphala compound’s extract, an Ayurvedic Rasayana ma…
Article
Hepatoprotective Potential of Methanolic and Aqueous Extract of Chenopodium botrys against Lead-induced Toxicity
Nidhi Gupta, Rakesh Sagar, Mohan Lal Kori
pp. 165–169 · DOI: 10.5530/ijpi.2021.2.30 · Published
Background:Chenopodium botrys L. is local to Europe and Asia and established in North America. The plant commonly used for the treatment of disease. The medicinal use of Chenopodium botrys is mainly due to mythology rath…
Article
Chemical Characterization, Antimicrobial, Antiproliferative and Antioxidant Activities of the Essential Oil of Monarda citriodora Growing in Kashmir
Abdul Rouf Wani, Kanchan Yadav
pp. 170–175 · DOI: 10.5530/ijpi.2021.2.31 · Published
Objectives:The main aim of this research was to evaluate phytochemicals, antimicrobial, antiproliferative and antioxidant Activities of the essential Oil of Monarda citriodora growing in Kashmir (India). Materials and Me…
Article
Arginase Enzyme Inhibition and with Subsequent Atheroprotection of Butanol Fraction of Rivea ornata in Lipid Emulsion Induced Atherosclerosis in Rats
Mallela Vijaya Jyothi, Nayakanti Devanna, Akkiraju Sudheer
pp. 176–183 · DOI: 10.5530/ijpi.2021.2.32 · Published
Objectives:Atherosclerosis is caused by vascular inflammation and oxidative stress. Pro-atherogenic effect of hypercholesterolemia caused by impairment of nitric oxide generation due to activated arginase. The current st…
Article
In vitro Toxicity Evaluation of Sterol Isolate from Echinoderm Stellaster equestris against Human Peripheral Blood
Ravindran Sumitha, Narasiman Banu, Swaminathan Vijayalakshmi, Venkatesan Krithika
pp. 184–188 · DOI: 10.5530/ijpi.2021.2.33 · Published
Background:Ocean acts as a wealthy resource of biological diversity producing prospective novel metabolites from the organisms present in the environment. Novel bioactive compounds from Echinoderms mainly from sea stars …
Article
Schiff Base Conjugate of 5-Fluoroisatin with Thiophene-2-Ethylamine and its Mannich Bases: Synthesis, Molecular Docking, and Evaluation of in vitro Anti-inflammatory and Anti-tubercular Activity
Bhushan Dnyandeo Varpe, Shailaja Bhanudas Jadhav
pp. 189–194 · DOI: 10.5530/ijpi.2021.2.34 · Published
Objectives:To synthesize Schiff base conjugate of 5-Fluoroisatin with thiophene-2-ethylamine and its Mannich bases and screen for anti-inflammatory and anti-tubercular activity. Materials and Methods:The compounds were s…
Article
Provesicular Based Colloidal Carriers for Transdermal Drug Delivery: Formulation Aspects and Bioavailability Enhancement of Acyclovir Proliposomal Gels
Mateti Ashok, Mohammed Habibuddin, Jukanti Raju
pp. 195–203 · DOI: 10.5530/ijpi.2021.2.35 · Published
Background:Acyclovir (ACV) a 21-deoxy guanosine analogue effective against Herpes Simplex Virus (both type 1 and 2) and other viral diseases, mainly acts by inhibiting the viral DNA polymerase. The limited oral bioavaila…
Article
Compositional Characterization of Biosurfactant Produced from Pseudomonas aeruginosa ENO14-MH271625 and its Application in Crude Oil Bioremediation
Ekramul Haque, Mohd Aamir Bin Riyaz, Sriram Shankar, Saqib Hassan
pp. 204–207 · DOI: 10.5530/ijpi.2021.2.36 · Published
Objectives:This study aimed to compositionally characterize the biosurfactant and its application in crude oil bioremediation. Methods:Production of biosurfactant was carried out in Bushnell Hass Broth (BHB), supplemente…
Article
Determination of Lapatinib in Bulk and Tablet Dosage Form using Ultraviolet Spectrophotometric and RP-HPLC Analytical Methods
Sumanta Mondal, Sabyasachi Biswal, Trayambica Acharya, Prasenjit Mondal, Kausik Bhar
pp. 208–213 · DOI: 10.5530/ijpi.2021.2.37 · Published
Objectives:The present article involved the development of sensitive and validated Ultraviolet (UV) Spectrophotometric and reverse phase liquid chromatographic and method for the determination of lapatinib in bulk and ph…
Article
Effect of Permeation Enhancer on Bioavailability of Formulated Patches of Glibenclamide
Ashish Kandalkar, Nitu Singh
pp. 214–219 · DOI: 10.5530/ijpi.2021.2.38 · Published
Objectives: The objective of this study is to extract Phytochemical constituent from Cinnamon Bark and to design and develop the transdermal patch of the herbal drug along with modern medicine Glibenclamide using solvent…
Article
Nanostructured Lipid Carrier (NLC) and Solid Lipid Nanoparticles (SLN) Based Hydrogel for Delivery of Etodolac: A Comparative Investigation on Dermal Pharmacokinetic on Rat Skin
Dilip Kumar Patel, Roohi Kesharwani, Vikas Kumar
pp. 220–224 · DOI: 10.5530/ijpi.2021.2.39 · Published
Objectives:The present work focus on to create Solid lipid nanoparticles (SLN) and nanostructured lipid Carrier (NLC) as transporters for effective delivery of Etodolac (ETD). Methods:Etodolac stacked SLN and NLC were se…
Article
Formulation Development of Celecoxib Loaded Microsponges using Eudragit and Ethyl Cellulose
Vishwajeet Swami, Amir A Shaikh, Pooja N Jadhav, Rahul S Buchade
pp. 225–229 · DOI: 10.5530/ijpi.2021.2.40 · Published
Background:Microsponge is a class of dosage form containing porous nature containing drug that is targeted to achieve sustained action for prolong period. Microsponge based delivery system results in drug localization on…
Article
Formulation, Optimization and in vitro Evaluation of Apremilast Nanoemulgel for Topical Delivery
Sindhoor Shridharan Mulleria, Koland Marina, Sawan Mukund Ghetia
pp. 230–237 · DOI: 10.5530/ijpi.2021.2.41 · Published
Background:Psoriasis is an autoimmune-mediated disease characterized marked by thickened plaques and erythematous skin, which can be treated by topical delivery of apremilast. The objective of this study was to prepare h…
Article
Evaluation of Efficacy and Safety of ‘AHPL/AYTOP/2014A’ in Patients Suffering from Aphthous Ulcers - An Open Label, Randomized, Multi-center, Prospective, Active Controlled, Parallel Group, Clinical Study
Sanjay Nipanikar, Narendra Mundhe, Vaishali Deshpande, Nitin Shinde, Mangesh Wakchaoure, Pravin Ghadge
pp. 238–243 · DOI: 10.5530/ijpi.2021.2.42 · Published
Background:Aphthous stomatitis is a painful and often inflammatory condition. Objective of the study is to evaluate safety and efficacy of Arimu mouth ulcer gel (AHPL/ AYTOP/2014A) in subjects suffering from aphthous ulc…
Article
Preparation and Validation of User-based Patients Information Leaflets (PILs) for COPD Patients in Indian Regional Languages: A Prospective Observational Study
Ruhul Amin, Biplab Kumar Dey, Suhaj Abdulsalim, Mohan K. Manu
pp. 244–247 · DOI: 10.5530/ijpi.2021.2.43 · Published
Objectives:Extensive literature survey revealed that chronic obstructive pulmonary disease (COPD) is one of the primary burdens for low-income countries like India. Out of around 30 million COPD patients in India, a cons…