International Journal of Pharmaceutical Investigation
Volume 4, Issue 1
· pp. 1–45 · 7 articles
- Volume
- 4
- Issue
- 1
- Published
- Pages
- 1–45
- Articles
- 7
- Sections
- 2
- ISSN
- Print - 2230-973X, Online -2230-9713
- Journal
- IJPI
In this issue
Review Article
- Review
Harnessing the potential of bacterial ghost for the effective delivery of drugs and biotherapeutics
Aditya Ganeshpurkar, Ankit Ganeshpurkar, Vikas Pandey, Abhishek Agnihotri, Divya Bansal, Nazneen Dubey
pp. 1–4 · DOI: 10.4103/2230-973X.127733 · Published
It seems to be a necessary need to develop an effective drug carrier system for targeted delivery of pharmaceuticals. Bacterial ghosts are emerging drug delivery platform that are capable of delivery of proteins, antigen…
Original Research Article
- Article
Thermosensitive periodontal sol of ciprofl oxacin hydrochloride and serratiopeptidase: Pharmaceutical and mechanical analysis
Kushal Pal Singh, Gulshan Chhabra, Vijay Sharma, Kamla Pathak
pp. 5–14 · DOI: 10.4103/2230-973X.127734 · Published
Aim: The aim of the present work was to explore the development of a dual-controlled release periodontal system of a potent broad spectrum fi rst-generation fl uoroquinolone, ciprofl oxacin, and the anti-infl ammatory en…
- Article
Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates
Suneela Pyreddy, Pandurangan Dinesh Kumar, Palanirajan Vijayaraj Kumar
pp. 15–18 · DOI: 10.4103/2230-973X.127735 · Published
Aim:The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported. Method and Materials: About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via …
- Article
Design, development and evaluation of clopidogrel bisulfate fl oating tablets
K Rama Koteswara Rao, K Rajya Lakshmi
pp. 19–26 · DOI: 10.4103/2230-973X.127736 · Published
Objective: The objective of the present work was to formulate and to characterize a fl oating drug delivery system for clopidogrel bisulphate to improve bioavailability and to minimize the side effects of the drug such a…
- Article
Preparation and evaluation of sublingual tablets of zolmitriptan
Shailesh T Prajapati, Manoj V Patel, Chhaganbhai N Patel
pp. 27–31 · DOI: 10.4103/2230-973X.127737 · Published
Aim:Zolmitriptan is a 5-HT receptor agonist (1B/1D). It is used in the acute treatment of migraine having low bioavailability about 40% orally due to hepatic first pass metabolism. The purpose of the present research was…
- Article
Preparation and evaluation of chitosan microspheres containing nicorandil
Keyur S Patel, Mandev B Patel
pp. 32–37 · DOI: 10.4103/2230-973X.127738 · Published
Objectives:The objective of present study was to develop chitosan-based sustained release nicorandil microspheres to reduce the dosing frequency. Materials and Methods:The nicorandil-loaded chitosan microspheres were for…
- Article
Formulation and evaluation of polyelectrolyte complexbased matrix tablet of Isosorbide Mononitrate
Iizhar Ahmed Syed, P Niveditha, Ismail Ahmad
pp. 38–45 · DOI: 10.4103/2230-973X.127739 · Published
Introduction:The polyelectrolyte Complexes (PECs) are based on ionic cross-linking. They have been employed to prepare a sustained release matrix tablets. These systems are based upon the fact that their structure can en…