International Journal of Pharmaceutical Investigation
Volume 5, Issue 3
· pp. 121–178 · 8 articles
- Volume
- 5
- Issue
- 3
- Published
- Pages
- 121–178
- Articles
- 8
- Sections
- 3
- ISSN
- Print - 2230-973X, Online -2230-9713
- Journal
- IJPI
In this issue
Editorial
- Forum Article
Nanomedicines for dental applications-scope and future perspective
Ramandeep Singh Narang, Jasjeet Kaur Narang
pp. 121–123 · DOI: 10.4103/2230-973X.160843 · Published
Nanotechnology is directed at manipulating matter at the nanometer level and the application of the same to medicine is called nanomedicine. Over the past few years researchers have developed various nanomedicines for di…
Review Article
- Review
Mesoporous silica nanoparticles in target drug delivery system: A review
Charu Bharti, Upendra Nagaich, Ashok Kumar Pal, Neha Gulati
pp. 124–133 · DOI: 10.4103/2230-973X.160844 · Published
Due to lack of specifi cation and solubility of drug molecules, patients have to take high doses of the drug to achieve the desired therapeutic effects for the treatment of diseases. To solve these problems, there are va…
Original Research Article
- Article
Synthesis and self-assembly of biodegradable polyethylene glycol-poly (lactic acid) diblock copolymers as polymersomes for preparation of sustained release system of doxorubicin
Mona Alibolandi, Fatemeh Sadeghi, Seyed Hossein Sazmand, Seyed Mohammad Shahrokhi, Mahmoud Seifi, Farzin Hadizadeh
pp. 134–141 · DOI: 10.4103/2230-973X.160846 · Published
Introduction:The copolymer of polyethylene glycol (PEG) and polyesters has many interesting properties, such as amphiphilicity, biocompatibility, biodegradability, and self-assembly in an aqueous environment. Diblock cop…
- Article
Enhancement of ketorolac tromethamine permeability through rat skin using penetration enhancers: An ex-vivo study
Pawan Kumar, Shailendra Kumar Singh, Dina Nath Mishra, Priti Girotra
pp. 142–146 · DOI: 10.4103/2230-973X.160850 · Published
Introduction: Ketorolac tromethamine (KT), a nonsteroidal anti-infl ammatory drug, when given orally causes gastrointestinal disturbances. Its transdermal drug delivery may reduce such side effects associated with them. …
- Article
Fabrication and optimization of camptothecin loaded Eudragit S 100 nanoparticles by Taguchi L4 orthogonal array design
Manikandan Mahalingam, Kannan Krishnamoorthy
pp. 147–154 · DOI: 10.4103/2230-973X.160852 · Published
Introduction:The objective of this investigation was to design and optimize the experimental conditions for the fabrication of camptothecin (CPT) loaded Eudragit S 100. Nanoparticles, and to understand the effect of vari…
- Article
Dual agents loaded polymeric nanoparticle: Effect of process variables
Deepak Sharma, Gilphy Philip, Reema Gabrani, Javed Ali, Shweta Dang
pp. 155–160 · DOI: 10.4103/2230-973X.160853 · Published
Aim and Objectives: In the present investigation dual agents i.e., hesperidin and diazepam loaded polymeric nanoparticles (NPs) were formulated by nanoprecipitation method and optimized using three-level factorial design…
- Article
Microspheres and tablet in capsule system: A novel chronotherapeutic system of ketorolac tromethamine for site and time specifi c delivery
Priya Shahi, Neeraj Kumari, Kamla Pathak
pp. 161–170 · DOI: 10.4103/2230-973X.160854 · Published
The objective of the present work was to develop a novel delivery system of ketorolac tromethamine (KT) for dual pulse release based on microspheres and tablet in capsule system (MATICS) as a treatment modality for rheum…
- Article
Preparation and characterization of cefuroxime axetil solid dispersions using hydrophilic carriers
Adinarayana Gorajana, Adhiyaman Rajendran, Lee Mun Yew, Kamal Dua
pp. 171–178 · DOI: 10.4103/2230-973X.160857 · Published
Aim:The objective of the current study is to increase the dissolution rate of cefuroxime axetil (CA) by formation of binary CA solid dispersion using water soluble carriers such as polyvinylpyrrolidone (PVP K30) and poly…