International Journal of Pharmaceutical Investigation
Volume 7, Issue 2
· pp. 41–110 · 10 articles
- Volume
- 7
- Issue
- 2
- Published
- Pages
- 41–110
- Articles
- 10
- Sections
- 3
- ISSN
- Print - 2230-973X, Online -2230-9713
- Journal
- IJPI
In this issue
Review Article
- Review
Compensation to clinical trial participants in India: A gap analysis
Mohd Urooj, Gulam Mohammed Husain, Mohammad Ahmed Khan, Munawwar Husain Kazmi
pp. 41–46 · DOI: 10.4103/jphi.JPHI_31_17 · Published
The recent amendments notified by the Government of India, for conducting clinical trial, is greatly appreciable as promoting safety and well‑being of human subjects. These rules clearly state that medical management of …
- Review
Application of three‑dimensional printing for colon targeted drug delivery systems
Nitin B Charbe, Paul A McCarron, Majella E Lane, Murtaza M Tambuwala
pp. 47–59 · DOI: 10.4103/jphi.JPHI_32_17 · Published
Orally administered solid dosage forms currently dominate over all other dosage forms and routes of administrations. However, human gastrointestinal tract (GIT) poses a number of obstacles to delivery of the drugs to the…
Original Research Article
- Article
Determining frequency of genes of CTX‑M and CTX‑M‑15 of producing Enterobacteriaceae of isolated extended‑spectrum beta‑lactamases from clinical samples of patients referred to training hospitals of Medical Sciences University, Khorramabad, Iran
Seyed Mojtaba Mosavian, Azam Rezvani‑Rad
pp. 60–69 · DOI: 10.4103/jphi.JPHI_4_17 · Published
Objective:The purpose of conducting this research was evaluation of the frequency of extended‑spectrum beta‑lactamases (ESBLs) in separated Enterobacteriaceae isolates from clinical samples in Khorramabad city and determ…
- Article
Brand versus generic dispensing trend for ciprofloxacin 500 mg, levofloxacin 500 mg, and moxifloxacin 400 mg (oral dosage forms) among pharmacies of Karachi, Pakistan
Fatima Zehra, Atta Abbas Naqvi, Sumbul Tasneem, Rizwan Ahmad, Niyaz Ahmad, Adnan Zia Shamsi, Naqiya Ali Asghar, Ghufran Ullah Khan
pp. 70–76 · DOI: 10.4103/jphi.JPHI_15_17 · Published
Introduction: Pakistan spends 0.7% of its gross domestic product on health. The public sector health‑care system provides services to 22% of population thus paving the way for a dominant private sector. Patients in Pakis…
- Article
Antifungal effects of Lactobacillus species isolated from local dairy products
Sahar Karami, Mohammad Roayaei, Elnaz Zahedi, Mahmoud Bahmani, Leila Mahmoodnia, Hosna Hamzavi, Mahmoud Rafieian-Kopaei
pp. 77–81 · DOI: 10.4103/jphi.JPHI_9_17 · Published
Objective: The Lactobacillusis a genus of lactic acid bacteria which are regularly rod‑shaped, nonspore, Gram‑positive, heterogeneous, and are found in a wide range of inhabitants such as dairy products, plants, and gast…
- Article
Synergistic effect of Carum copticum and Mentha piperita essential oils with ciprofloxacin, vancomycin, and gentamicin on Gram‑negative and Gram‑positive bacteria
Gholam-Reza Talei, Mohsen Mohammadi, Mahmoud Bahmani, Mahmoud Rafieian Kopaei
pp. 82–87 · DOI: 10.4103/jphi.JPHI_12_17 · Published
Background:Infectious diseases have always been an important health issue in human communities. In the recent years, much research has been conducted on antimicrobial effects of nature‑based compounds because of increase…
- Article
Comparison of effectiveness of Calendula officinalis extract gel with lycopene gel for treatment of tobacco‑induced homogeneous leukoplakia: A randomized clinical trial
Manisha Singh, Anjana Bagewadi
pp. 88–93 · DOI: 10.4103/jphi.JPHI_19_17 · Published
Aim:The aim of the study is to assess the efficacy of Calendula officinalis gel as cost‑effective treatment modality in comparison to lycopene gel in the treatment of leukoplakia. Materials and Methods:The study comprise…
- Article
Simultaneous determination of rutin, isoquercetin, and quercetin flavonoids in Nelumbo nucifera by high‑performance liquid chromatography method
P Naveen, HB Lingaraju, Anitha A, K Shyam Prasad
pp. 94–100 · DOI: 10.4103/jphi.JPHI_33_17 · Published
Objective: The present study was investigated to provide a documentary evidence for the determination of rutin, isoquercetin, and quercetin flavonoids from the flora of Nelumbo nuciferaby reversed‑phase high‑performance …
- Article
Thermoreversible in situ gel for subgingival delivery of simvastatin for treatment of periodontal disease
Swaminathan Rajendran, K. Sathesh Kumar, S Ramesh, Suresh Ranga Rao
pp. 101–106 · DOI: 10.4103/jphi.JPHI_26_17 · Published
Objective: The aim of this in vitro study was to formulate an in situ thermoreversible injectable gel with poloxamer (PM) and methylcellulose (MC) to deliver simvastatin (SMV) in a controlled manner. Subjects and Methods…
Case Report
- Article
Prosthetic rehabilitation of a geriatric patient with squamous cell carcinoma of the buccal mucosa: A report of clinical challenges
Raghavendra Adaki, Sarvesh Raikar, Kamal Shigli, Sivaranjani Gali
pp. 107–110 · DOI: 10.4103/jphi.JPHI_17_17 · Published
Objective: This article aims to highlight the rehabilitation of a geriatric patient with an orofacial cheek defect by an extraoral silicone prosthesis. Methodology:Structured extra‑ and intra‑oral examination of tissues …