Volume 13, Issue 1

Nayesha Mahwish, Laxminarayana Kurady Bairy, Sureshkumar Srinivasamurthy

pp. 5–13 · DOI: 10.1177/0976500X221080378 · 2022

Antivitamins are compounds that negate the biological effects of vitamins. They have been successfully exploited for the development of various classes of drugs. In the early 19th century, the antifolate prontosil was de…

Pooja Raina, Somnath Basu, Ramesh K Goyal, Pravat K Sahoo, Rajani Mathur

pp. 14–23 · DOI: 10.1177/0976500X221080225 · 2022

Three monoclonal antibodies—natalizumab (NTZ), ocrelizumab (OCR), and alemtuzumab (ALM)—are the mainstays for the treatment of both relapsing and progressive forms of multiple sclerosis (MS). Here, their safety in patien…

Wisam Al Jumaili, Ashraf Muzwagi

pp. 24–30 · DOI: 10.1177/0976500X221080296 · 2022

Objectives: To shed some light on the understudied complication of chronic prolonged exposure to antipsychotics (AP) in children with consideration to with autism spectrum disorder (ASD). Methods: We electronically searc…

Jiju Narayanan Avanipully, Dithu Thekkekkara, Sahyadri M, Vipan K. Parihar, Santhepete Nanjundaiah Manjula

pp. 31–39 · DOI: 10.1177/0976500X221085802 · 2022

Parkinson’s disease (PD) mainly affects the dopaminergic neuronal networks of the substantia nigra, which leads to both motor and nonmotor symptoms of the disease. Based on the reports from the previous studies, 95% of t…

Sandeep Grover, B.M. Gupta, K.K. Mueen Ahmed

pp. 40–47 · DOI: 10.1177/0976500X221080393 · 2022

Aim: This study aimed to assess the characteristics and trends of research on substance use and COVID-19. Methods: Keywords related to “Covid-19” and “Substance Use” were used in a search query formulated for the Scopus …

Chaman Sab M., Mallikarjun Kappi, K.K. Mueen Ahmed

pp. 48–58 · DOI: 10.1177/0976500X221082839 · 2022

The current research has been conducted to study the ethnopharmacology research output in the past 10 years (2011–2020) after using Web of Science (WoS) database. The present study has used WoS database to collect the et…

Shilpa Sarang Kore, Smita Bhau Ubhe, Fathima Fasil

pp. 59–65 · DOI: 10.1177/0976500X221085803 · 2022

Objective: To compare the effects of dexamethasone and fentanyl when added to a mixture of bupivacaine and lignocaine in supraclavicular blocks in patients undergoing forearm surgeries. Methods: Sixty-six patients aged b…

E. Pasangha, B. George, K. B. Bhuvana, D. Padmini

pp. 66–71 · DOI: 10.1177/0976500X221080291 · 2022

Objective: To assess the patterns and predictors of pharmacotherapy and QOL in DFS patients in an Indian tertiary care hospital. Methods: A cross-sectional study was conducted among inpatients with DFS. Data on sociodemo…

Hari Prabhath Tummala, Rachana Balusu, Sahithi Thotakura, Achyuth Kumar Pasnoor, Arun Prasath Raju, Shivakumar Mahadeva Lal, Leslie Edwards Lewis, Surulivelrajan Mallayasamy

pp. 72–78 · DOI: 10.1177/0976500X221080209 · 2022

Objective: To develop a physiologically based pharmacokinetic (PBPK) model for individualization of the dosing regimen considering the physiological requirements of these preterm neonates. Methods: The study comprised pr…

Kothari Saroj, Bansal Haresh, Paharia Yogendra

pp. 79–84 · DOI: 10.1177/0976500X221080380 · 2022

Objective: To study the safety and efficacy of low-dose etoricoxib and low-dose paracetamol versus ibuprofen and low-dose paracetamol treatments in patients who experienced acute pain after tooth extraction. Methods: A t…

Fathima Fasil, Girish Saundattikar, Reema Hemant Jawale, Naveen Kumar J.

pp. 85–91 · DOI: 10.1177/0976500X221080390 · 2022

Objective: To observe the hemodynamic effects of a single bolus dose of dexmedetomidine in patients undergoing elective laparoscopic surgeries. Methods: A total of 60 adult patients were randomized into two groups of 30 …

Pallavi Jha, Sneha Ambwani, Surjit Singh, Pankaj Bhardwaj, Shobhan Babu Varthya, Jaykaran Charan

pp. 92–94 · DOI: 10.1177/0976500X221080370 · 2022

World Health Organization (WHO) defines essential drugs or medicines as “those drugs that satisfy the healthcare needs of majority of the population; they should therefore be available at all times in adequate amounts an…

Shridhar Dwivedi, Vinod Sharma, C. R. Patil

pp. 95–96 · DOI: 10.1177/0976500X221080202 · 2022

COVID-19 is known to cause several cardiac disorders such as pancarditis, coronary artery disease (CAD), arrhythmias, cardiomyopathy, and stroke during and after the active stage of the COVID-19 infection, even when the …

Hardik Gandhi

pp. 97–98 · DOI: 10.1177/0976500X221080392 · 2022

Olanzapine, a second-generation antipsychotic, is indicated for the treatment of schizophrenia and bipolar disorder.1 Oral formulations of olanzapine include standard oral tablets (SOT) and orally disintegrating tablets …

K. Geetha, Puja Puja

pp. 99–101 · DOI: 10.1177/0976500X221080309 · 2022

Hypoglycemic drugs in the dipeptidyl peptidase-4 (DPP-4) inhibitor class are used as a second-line treatment for type 2 diabetes mellitus. With DPP-4 inhibitors, there have been a few reports of cutaneous side effects su…

Ankit Bhardwaj, Shoma Mukherjee, Vandana Roy

pp. 102–107 · DOI: 10.1177/0976500X221080224 · 2022

Xylometazoline, a sympathomimetic available as over the counter drug, acts as a nasal decongestant and has been reported as an independent risk factor for hemorrhagic and ischemic stroke. The chronic use of xylometazolin…