Volume 3, Issue 2

Subramani Parasuraman, Ramasamy Raveendran

pp. 87–93 · DOI: 10.4103/0976-500X.95521 · 2010

Blood pressure (BP) is one of the vital parameters used to assess the cardiovascular functions of a mammal. BP is commonly recorded using invasive, noninvasive, and radio telemetry methods, but invasive blood pressure (I…

Anant Bhan

pp. 95–97 · DOI: 10.4103/0976-500X.95501 · 2012

The recent reporting of controversial drug trials being conducted by doctors of the government medical college and private practitioners on ‘mentally challenged’ patients in Indore has caused uproar.[5] It was alleged th…

Naveen Chhabra, M. L. Aseri, Ramakant Dixit, S. Gaur

pp. 98–104 · DOI: 10.4103/0976-500X.95502 · 2012

The current global concern in the treatment of tuberculosis (TB) is the emergence of resistance to the two most potent drugs namely, isoniazid and rifampicin. Emergence of multidrug resistance tuberculosis (MDR- TB) is n…

Sumit Kar, Ajay Krishnan, Preetha K., Atul Mohankar

pp. 105–108 · DOI: 10.4103/0976-500X.95503 · 2012

Antihistamines are one of the most common drugs that are used extensively in various dermatological and nondermatological conditions. The use of H-1-antihistamines during pregnancy has been very controversial due to poss…

Shilpa P. Jadav, Dinesh M. Parmar

pp. 109–111 · DOI: 10.4103/0976-500X.95504 · 2012

Unwanted pregnancy is a global reproductive health problem. Emergency contraception is defined as the use of drug or device after unprotected or underprotected intercourse to prevent an unwanted pregnancy. 1.5 mg of levo…

Ashish P. Anovadiya, Jayesh J. Sanmukhani, C. B. Tripathi

pp. 112–117 · DOI: 10.4103/0976-500X.95505 · 2012

Despite of established and effective therapy for epilepsy, 20–25% patients develop therapeutic failure; this encourages finding newer drugs. Novel approaches target receptors which remain unaffected by conventional thera…

Rathish Nair, Arun Maseeh

pp. 118–126 · DOI: 10.4103/0976-500X.95506 · 2012

Vitamin D insufficiency affects almost 50% of the population worldwide. An estimated 1 billion people worldwide, across all ethnicities and age groups, have a vitamin D deficiency (VDD). This pandemic of hypovitaminosis …

Dilip Gude

pp. 127–131 · DOI: 10.4103/0976-500X.95507 · 2012

The rapidly increasing prevalence of diabetes on a global scale beseeches an urgent need for newer and better treatment options. Our better understanding of the pathophysiology of diabetes has enabled a continual churn o…

Amany Mohamed Shalaby, Sahar Mohamed Kamal

pp. 132–137 · DOI: 10.4103/0976-500X.95509 · 2012

Objectives: To investigate the alterations in GABA levels by rolipram in the model of depression. Materials and Methods: The alteration of GABA content by rolipram as a phosphodiesterase enzyme type-4 inhibitor in the fr…

Kakjing D. Falang, P. Akubaka, N. S. Jimam

pp. 138–142 · DOI: 10.4103/0976-500X.95511 · 2012

Objective: To study the adherence levels and explore factors impacting them in out-patients on antiretroviral therapy (ART) at the AIDS Prevention Initiative in Nigeria antiretroviral clinic of the Jos University Teachin…

José Sereno, Ana M. Romão, Belmiro Parada, Patrícia Lopes, Eugénia Carvalho, Frederico Teixeira, Flávio Reis

pp. 143–148 · DOI: 10.4103/0976-500X.95513 · 2012

Objective: To compare the cardiorenal effects of early versus late cyclosporine (CsA) to sirolimus (SRL) conversion, using a novel animal model that mimics these protocols used in the clinical practice, and focusing on b…

Kunal B. Kapadia, Parloop A. Bhatt, Jigna S. Shah

pp. 156–160 · DOI: 10.4103/0976-500X.95517 · 2012

Objective: To determine the association between altered thyroid hormones and insulin resistance (IR). Materials and Methods: Eight euthyroid (EU), eight hypothyroid (HO), and eight hyperthyroid (HR) patients with no past…

Mrinmoy Chakrabarty, Priyanka Bhat, Sweta Kumari, Avin D’Souza, K. L. Bairy, Abhishek Chaturvedi, Archana Natarajan, Mohandas Rao K. G., Shobha Kamath

pp. 161–171 · DOI: 10.4103/0976-500X.95520 · 2012

Objective: To investigate the effects of Celastrus paniculatus seed oil in preventing the onset of chronic aluminum induced cortico-hippocampal neurodegeneration and oxidative stress. Materials and Methods: An animal mod…

C. Girish, S. C. Pradhan

pp. 149–150 · DOI: 10.4103/0976-500X.95515 · 2012

Introduction:To evaluate the hepatoprotective activity of active phytochemicals, picroliv, curcumin, and ellagic acid in comparison to silymarin in the mice model of carbon tetrachloride (CCl4) induced liver toxicity. In…

Pitchai Balakumar, Gowraganahalli Jagadeesh

pp. 178–179 · DOI: 10.4103/0976-500X.95522 · 2012

The 63rd Annual Conference of the Indian Pharmaceutical Congress (IPC) was held in Bengaluru, India, from 16 to 18 December 2011. It was hosted by the Karnataka state branch of the ‘Indian Pharmaceutical Association’. Th…

Arti Gupta, N. R. Sheth, Sonia Pandey, Jitendra S. Yadav, D. R. Shah, B. Vyas, S. Joshi

pp. 183–184 · DOI: 10.4103/0976-500X.95523 · 2012

The liver is the second largest organ in the body, and is often seen as the most important one. Toxins, infectious agents, medications, and serum inflammatory mediators may result in a diverse range of disease processes,…

Isabella Topno, B. Chennama, B. Yugandhar, S. Balakrishnan

pp. 190–191 · DOI: 10.4103/0976-500X.95526 · 2012

Drug utilization research is defined by World Health Organization (WHO) as the marketing, distribution, prescription and use of drugs in a society, with special emphasis on the resulting medical, social and economic cons…

Yasir Hasan Siddique, Mohammad Afzal

pp. · DOI: 10.4103/0976-500X.95525 · 2012

A transgenic Drosophila melanogaster line expressing bacterial b-galactosidase as a response to stress was used in this study.[6] The flies and larvae were cultured on standard Drosophila food containing agar, cornmeal, …

Isabella Topno, B. Chennama, B. Yugandhar

pp. · DOI: 10.4103/0976-500X.95527 · 2012

S. tetragonum root was collected from Tirunelveli district of Tamilnadu and identified by taxonomists of Tropical Botanic Garden and Research Institute (TBGRI) and a voucher specimen (TBGRI 8282) has been deposited. The …

Biswajit Dubashi, Ankit Jain

pp. 194–195 · DOI: 10.4103/0976-500X.95531 · 2012

l-Asparginase is used for remission induction in acute lymphoblastic leukemia. We describe a case of 16-year-old boy who developed cortical venous thrombosis following the administration of l-Asparginase.