Journal of Pharmacology and Pharmacotherapeutics
Volume 4, Issue 2
2013 · pp. 83–182 · 22 articles
- Volume
- 4
- Issue
- 2
- Published
- 2013
- Pages
- 83–182
- Articles
- 22
- Sections
- 12
- ISSN
- Print - 0976-500X, Online - 0976-5018
- Journal
- JPP
In this issue
1–20 of 22Editorial
- Forum Article
Mostafa Yakoot
pp. 83–85 · DOI: 10.4103/0976-500X.110868 · 2013
Complementary Alternative Medicine (CAM) was defined as “those treatments and health care practices that are not an integral part of conventional western medicine, not taught in medical schools, and not generally used in…
Review Article
- Review
Lisha J. John
pp. 86–90 · DOI: 10.4103/0976-500X.110870 · 2013
Laboratory based practical classes, have been the corner stone of undergraduate pharmacology learning. Ethical issues with the use of animals and rapid development of information technology has led to newer trends in tea…
Research Paper
- Article
Maulik Patel, Vinay Mishra, Vaibhavi Pawar, Ramchandran Ranvir, Rajesh Sundar, Rajas Dabhi
pp. 87–93 · DOI: 10.4103/0976-500X.110891 · 2010
Objectives: To explore the general physiological and molecular changes occurring as a result of acute hypothyroidism. Materials and Methods: Hypothyroidism was developed by thyroidectomy in wistar rats. After surgery, an…
- Article
Lucas Gasco, Margaret B. Rosbolt, Vikhyat S. Bebarta
pp. 95–102 · DOI: 10.4103/0976-500X.110875 · 2013
Objective: To identify the influence of catchment area, trauma center designation, hospital size, subspecialist employment, funding source, and other hospital characteristics on cyanide antidote stocking choice in US hos…
- Article
Seethalakshmi Sreenivasan, Sathyabaarathi Ravichandran, Umashankar Vetrivel
pp. 103–109 · DOI: 10.4103/0976-500X.110882 · 2013
Objective: To determine the possible interaction of curcumin with P‑glycoprotein (P‑gp) expression and function by in vitro and in silico studies. Materials and Methods: In this study, curcumin was compared for its poten…
- Article
Shailaja B. Khobragade, Pankaj Gupta, Prashant Gurav, Girish Chaudhari, Madhumanjiri M. Gatne
pp. 116–124 · DOI: 10.4103/0976-500X.110892 · 2013
Objectives: To evaluate the prolongation of ventricular repolarization and proarrhythmic activity of antimalarial drug chloroquine in two rabbit proarrhythmia models viz., in vivo α1 adrenoceptor‑stimulated anesthetized …
Mini Review
- Article
Dhriti K. Brahma, Julie B. Wahlang, Maxilline D. Marak, Marlina Ch. Sangma
pp. 91–92 · DOI: 10.4103/0976-500X.110872 · 2013
Medications probably are the single most important health care technology in preventing illness, disability, and death in the geriatric population. Age-related changes in drug disposition and pharmacodynamic responses ha…
Methods
- Article
Alok Saxena, Vijay Thawani, Mrinmoy Chakrabarty, Kunda Gharpure
pp. 125–126 · DOI: 10.4103/0976-500X.110894 · 2013
Worthiness of any scientific journal is measured by the quality of the articles published in it. The Impact factor (IF) is one popular tool which analyses the quality of journal in terms of citations received by its publ…
Research Letter
- Article
S. Kannan, S. P. Deshpande, N. J. Gogtay, U. M. Thatte
pp. 139–140 · DOI: 10.4103/0976-500X.110897 · 2013
Although statistical methods are a vital part of research methodology, the quality of reporting statistics in published medical literature remains low containing a large number of statistical errors and deficiencies.[1‑3…
- Article
Lukshmy M. Hettihewa, Kalana Jayarathna, Sewwandi Subasinghe
pp. 142–143 · DOI: 10.4103/0976-500X.110898 · 2013
Although modern medicine has changed for better dispensing managements, the evidence still continues to mount that adverse drug reactions to medicine related to dispensing practices. The risk associated with dispensing o…
- Article
Nagendra S. Chunduri, Tanveer Kollu, Venkateswarulu R. Goteki, Kiran K. Mallela, Krishnaveni Madasu
pp. 144–145 · DOI: 10.4103/0976-500X.110904 · 2013
This study was conducted among fifty patients, aged from 18‑60 years, who require surgical removal of impacted mandibular third molars. Patients with blood dyscrasias, with peptic ulcer, pregnant women, patients who had …
- Article
Nagendra S. Chunduri, Tanveer Kollu, Venkateswarulu R. Goteki, Kiran K. Mallela, Krishnaveni Madasu
pp. 145–148 · DOI: 10.4103/0976-500X.110910 · 2013
Significantly higher pain and FLACC behavior scale score were observed with fentanyl at 2 hours as compared to adenosine 15‑50 µg/kg/min [Table 1]. Fentanyl and adenosine 15‑50 µg/ kg/min had shown significantly less FLA…
Case Report
- Article
Natasha Kate, Sandeep Grover, Munish Aggarwal, Pankaj Malhotra, Manupdesh S. Sachdeva
pp. 149–151 · DOI: 10.4103/0976-500X.110913 · 2013
Although agranulocytosis as a side effect of clozapine is well known, there is scarcity of data with regard to thrombocytopenia associated with clozapine. In this report we describe a case of clozapine induced thrombocyt…
- Article
Satyendra Kumar Singh, Kajal Manchanda, Aakash Amar Bhayana, Anurag Verma
pp. 152–154 · DOI: 10.4103/0976-500X.110915 · 2013
Granuloma annulare (GA) is a benign, inflammatory dermatosis involving dermis or subcutis with unknown etiology and poorly understood pathology. GA has characteristic histological features of necrobiosis, granuloma forma…
- Article
Pallavi Dhanvijay, Arup K. Misra, Sushil K. Varma
pp. 155–157 · DOI: 10.4103/0976-500X.110916 · 2013
Non‑steroidal anti‑inflammatory drugs (NSAIDs) are one of the most commonly prescribed drugs in post‑operative period worldwide. Their nephrotoxic effects are documented and accounts for around 15.5% of all cases of drug…
- Article
Kolar Vishwanath Vinod, Karyampudi Arun, Tarun Kumar Dutta
pp. 158–160 · DOI: 10.4103/0976-500X.110917 · 2013
Dapsone can cause several adverse effects, the most serious being dapsone hypersensitivity syndrome (DHS), which is potentially fatal. Here we report a case of severe, life threatening dapsone systemic hypersensitivity s…
Correspondence
- Article
Nicholas G. Kounis
pp. 161–162 · DOI: 10.4103/0976-500X.110918 · 2013
In the very interesting report published recently in this Journal[1] a 58‑year‑old female patient, suffering from acute myeloid leukemia, developed bradycardia and hypotension culminating to fatal complete heart block, f…
Commentary
- Article
Anupama Sukhlecha
pp. 164–165 · 2013
Credit points are being distributed like prasad (temple offerings). Just to gain credit hours, doctors are attending different specialty CME meets.[5] Our body cannot be compartmentalized to subjects, so, any doctor can …
News and Views
- Article
Sivagnanam G
pp. 166–7 · DOI: 10.4103/0976-500X.110922 · 2013
Early intestinal colonization with Lactobacilli and Bifidobacteria support the concept of their ability to modify the gut microbiota with beneficial roles like reduction in the risk of cancer due to their capacity to dec…
- Article
pp. 166–166 · 2013
Intestinal flora, called as microbiota, when disturbed has been associated with many GI and non‑GI diseases,[2] such diseases include, Clostridium difficile infection (CDI), inflammatory bowel disease (IBD), irritable bo…

