Journls JOURNAL OF PHARMACOLOGY AND PHARMACOTHERAPEUTICS Volume 4 · Issue 3 2013 · pp. 171–224
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Cover: Journal of Pharmacology and Pharmacotherapeutics

Journal of Pharmacology and Pharmacotherapeutics

Volume 4, Issue 3

2013 · pp. 171–224 · 15 articles

Volume
4
Issue
3
Published
2013
Pages
171–224
Articles
15
Sections
11
ISSN
Print - 0976-500X, Online - 0976-5018
Journal
JPP

In this issue

Editorial

  1. Forum Article

    Improving quality of medical education in India: The need to value and recognize academic scholarship

    Thomas V. Chacko

    pp. 171–173 · DOI: 10.4103/0976-500X.114595 · Published 2013

    We are all currently in the midst of a high tide of concern and clamor for taking urgent action to improve the standards of the medical education in the country. In this context, there have been some refreshing initiativ…

Commentary

  1. Article

    The metabolic syndrome and schizophrenia: A comorbidity or an association?

    pp. 174–175 · DOI: · Published 2013

    Individuals with schizophrenia have 2-3 times higher rates of mortality than the general population. Causes of excessive mortality are increased suicide rates and mortality of natural causes such as cardiovascular events…

Review Article

  1. Review

    Metabolic syndrome in schizophrenia: Differences between antipsychotic‑naïve and treated patients

    Rakesh K. Chadda, Prashanth Ramshankar, Koushik S. Deb, Mamta Sood

    pp. 176–176 · DOI: 10.4103/0976-500X.114596 · Published 2013

    Metabolic syndrome (MetS) has been recognized as a risk factor for cardiovascular morbidity and mortality in general population and in patients with severe mental illnesses like schizophrenia. This paper reviews studies …

Mini Review

  1. Article

    N-acetyl cysteine in clomiphene citrate resistant polycystic ovary syndrome: A review of reported outcomes

    Lekha Saha, Sharonjeet Kaur, Pradip Kumar Saha

    pp. 187–188 · DOI: 10.4103/0976-500X.114597 · Published 2013

    Clomiphene citrate (CC) has been the gold‑standard drug for ovulation induction in polycystic ovary syndrome (PCOS), but still CC resistance is seen in approximately 15-40% in women with PCOS. N‑acetyl cysteine (NAC), a …

Research Paper

  1. Article

    Neuroprotective role of naringenin on carbaryl induced neurotoxicity in mouse neuroblastoma cells

    Vijaya Prakash Krishnan Muthaiah, Lavanya Venkitasamy, Felicia Mary Michael, Kirubhanand Kirubhanand

    pp. 192–197 · DOI: 10.4103/0976-500X.114599 · Published 2013

    Objective: Neuroprotective effect of naringenin against carbaryl toxicity was studied in mouse neuroblastoma cell line. Materials and Methods: Mouse neuroblastoma cells (Neuro 2A) obtained from National Center for Cell S…

  2. Article

    Effects of structural analogues of apelin‑12 in acute myocardial infarction in rats

    Oleg I. Pisarenko, Larisa I. Serebryakova, Irina M. Studneva, Yulia A. Pelogeykina, Olga V. Tskitishvili, Zhanna D. Bespalova, Maria V. Sidorova, Andrei A. Az’muko, Denis N. Khatri, Maria E. Pal’keeva

    pp. 198–203 · DOI: 10.4103/0976-500X.114600 · Published 2013

    Objective: To examine cardioprotective effects of С‑terminal fragment of adipokine apelin‑12 (A12), its novel structural analogue [MeArg1, NLe10]‑A12 (I), and [d‑Ala12]‑A12 (II), a putative antagonist of APJ receptor, em…

Research Letter

  1. Article

    Audit of use of antibiotics and zinc supplement in childhood diarrhea

    Kalahasthi Priyadarshini, Vishnu Raj, Sadasivam Balakrishnan

    pp. 204–205 · DOI: 10.4103/0976-500X.114601 · Published 2013

    Diarrhea refers to the passage of loose or watery stools, and occurs at some point in the life of nearly every child. It continues to be a global problem in children, which accounts for 18% of child deaths and 13% of all…

  2. Article

    Modulation of inflammatory pain in response to a CCR2/CCR5 antagonist in rodent model

    Masayuki Okamoto, Takeshi Suzuki, Nobuhide Watanabe

    pp. 208–210 · DOI: 10.4103/0976-500X.114605 · Published 2013

    C‑C chemokine ligand 2 (CCL2), previously referred to as monocyte chemoattractant protein‑1 (MCP‑1), a 78 amino acid secreted protein, belongs to the CC subfamily and controls the recruitment of monocytes, memory T‑cells…

Methods

  1. Article

    An experimental spinal cord injury rat model using customized impact device: A cost-effective approach

    Vijayaprakash K.M, Sridharan N.

    pp. 211–213 · DOI: 10.4103/0976-500X.114607 · Published 2013

    Till date, NYU MASCIS (New York University, Multicenter Animal Spinal Cord Injury Study) impactor and Ohio State University electromagnetic spinal cord injury device impactor were under use for simulating an experimental…

Case Report

  1. Article

    Pseudocyesis: A complication of antipsychotic-induced increased prolactin levels and weight gain

    Sandeep Grover, Akhilesh Sharma, Deepak Ghormode, Nikita Rajpal

    pp. 214–216 · DOI: 10.4103/0976-500X.114610 · Published 2013

    Pseudocyesis or phantom pregnancy is characterized by a false belief in a non-pregnant female that she is pregnant and this belief is usually associated with bodily signs of pregnancy. In some of the patients, this belie…

Correspondence

  1. Article

    Good! Is it the best???

    Sandhiya Selvarajan, Steven Aibor Dkhar, Ajith Ananthakrishna Pillai

    pp. 220–221 · DOI: 10.4103/0976-500X.114611 · Published 2013

    The published article comparing ranolazine 500 mg BD and ivabradine 5 mg BD over 8 weeks has shown a reduction in the number of angina attacks per week from baseline angina frequency of 1.8 ± 0.2/week to complete absence…

Letter to the Editor

  1. Article

    Reply to “Good! is it the best ???

    Aditi Chaturvedi, Yogendra Singh, Harish Chaturvedi, Vijay Thawani, Sakshi, Deepak Parihar

    pp. 221–222 · DOI: 10.4103/0976-500X.114622 · Published 2013

    The questions that were put forth to the patients were similar to those that were followed in the ERICA trial, i.e., patients were evaluated for average frequency of self‑reported anginal episodes during the treatment ph…

News and Views

  1. Article

    Baldness, a new marker for coronary heart disease risk

    Sivagnanam G

    pp. 223–224 · DOI: · Published 2013

    A meta‑analysis of observational studies comprising a total of 36,690 participants showed that vertex baldness is associated with an increased risk of CHD with the relationship depending on the severity of baldness while…

  2. Article

    Majority general practitioners prescribe “Impure Placebo” drugs

    pp. 223–223 · DOI: · Published 2013

    “Pure placebos are interventions like sugar pills, which are available commercially or saline injections without direct pharmacologically active ingredients for the condition being treated.

  3. Article

    A new drug belonging to a novel class of drugs for type 2 diabetes

    Sivagnanam G

    pp. 224–224 · DOI: 10.4103/0976-500X.114621 · Published 2013

    The FDA approval of canagliflozin (Invokana) was based on data involving over 10,285 type 2 diabetes patients, which showed improvement in hemoglobin A1c and fasting plasma glucose levels. Canagliflozin has been tested a…