Volume 8, Issue 4

Lercanidipine in the Management of Hypertension: An Update

Guido Grassi, Nicolàs R. Robles, Gino Seravalle, Francesco Fici

pp. 155–65 · DOI: 10.4103/jpp.JPP_34_17 · Published 2017

Calcium channel blockers (CCBs), particularly dihydropyridine-CCBs, (DHP-CCBs), have an established role in antihypertensive therapy, either as monotherapy or in combination with other antihypertensive drugs. Two hundred…

Efficacy and Safety of Oral Diclofenac Sustained release Versus Transdermal Diclofenac Patch in Chronic Musculoskeletal Pain: A Randomized, Open Label Trial

Viraj Ashok Shinde, Mrunalini Kalikar, Satyajeet Jagtap, Ganesh N. Dakhale, Mangesh Bankar, Chaitali S. Bajait, Vijay M. Motghare, Ashlesha A. Pashilkar, Latesh B. Raghute, Ajita D. Khamkar

pp. 166–171 · DOI: 10.4103/jpp.JPP_35_17 · Published 2017

Introduction: To compare the efficacy, safety, and tolerability of transdermal patches of diclofenac sodium with oral diclofenac sustained release (SR) in patients of chronic musculoskeletal MSK pain conditions. Material…

Learning Pharmacology by Metaphors: A Tale of Beta‑blockers

pp. 172–5 · DOI: 10.4103/jpp.JPP_104_17 · Published 2017

The metaphoric language keeps the learner engaged in finding an association between known to unknown and therefore, helps him understand the otherwise difficult areas of a topic. A well‑constructed metaphor or analogy by…

Vitamin B12 Supplementation and Methylcobalamin: Use or Misuse

Khichar Purnaram Shubhakaran

pp. 176–176 · DOI: 10.4103/jpp.JPP_109_17 · Published 2017

Levosulpiride-induced Movement Disorders

Supriyo Choudhury, Koustav Chatterjee, Ravi Singh, Shantanu Shubham, Santosh Trivedi, Suparna Chatterjee, Hrishikesh Kumar

pp. 177–81 · DOI: 10.4103/jpp.JPP_32_17 · Published 2017

We reported a series of patients who presented with LSP-induced movement disorders specifically, dyskinetic movements. We have presented one case of LSP-induced parkinsonism and summarized ten cases of LSP-induced dyskin…

Low-Dose Mirtazapine-Induced Nightmares Necessitating its Discontinuation in a Young Adult Female

Vikas Menon, Pravallika Madhavapuri

pp. 182–4 · DOI: 10.4103/jpp.JPP_116_17 · Published 2017

Mirtazapine is a novel tetracyclic antidepressant which enhances noradrenergic and serotonergic transmission by blocking central α2‑adrenergic auto‑ and hetero‑receptors. Due to favorable safety and adverse effect profil…

Autopsy-proven Mirtazapine Withdrawal-induced Mania/Hypomania Associated with Sudden Death

Rena Pombo, Etta Johnson, Alejandra Gamboa, Bennet Omalu

pp. 185–187 · DOI: 10.4103/jpp.JPP_162_16 · Published 2017

Manic episodes induced by antidepressant withdrawal are rarely reported. Mirtazapine is a tetracyclic, piperazinoazepine compound and is a noradrenergic, adrenergic, serotonergic, histaminergic, and muscarinic-antagonist…