jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Journal of Young PharmacistsNOW IN
Article

The Preparation and Characterization of Ethanol Extract Nanoparticle from Rhaphidophora pinnata (L.f.) Schott Leaves by using Arabic Gum and Dextrin

Sumaiyah S1★, Masfria M1, Izmi Yolanda Rusdi1, Aminah Dalimunthe1★ Corresponding author

  1. 1Faculty of Pharmacy, Universitas Sumatera Utara, Medan, INDONESIA.

CORRESPONDENCE

Sumaiyah S

Faculty of Pharmacy, Universitas Sumatera Utara, Medan, INDONESIA.

sumaiyah@usu.ac.id

Received: 12-01-2018; Revised: 28-01-2018; Accepted: 12-03-2018.

Volume 10, Issue 2S · pp. s84–s86 · PUBLISHED · DOI: 10.5530/jyp.2018.2s.16

View on JYP original site ↗

ABSTRACT

Objective: This research was aimed to prepare and characterize the ethanol extract nanoparticles of Rhaphidophora pinnata leaves by using arabic gum and dextrin. Method: The Rhaphidophora pinnata leaves extract was obtained via the percolation method using ethanol 96% and followed by evaporation process to form a thickened extract. The total water content and ash of the ethanol extract fromRhaphidophora pinnata leaves were determined. The ethanol extract of Rhaphidophora pinnata leaves was turned into nanoparticles by mixing the extract with arabic gum and dextrin. Then, it was sieved using a 20 mesh sieve. The resulting granules were dried in the oven at 40-45°C. The dried granules were milled with ball milling equipment to obtain a powder in nanometer scale. The nanoparticle powder was then characterized using a Particle Size Analyzer to investigate its particle size and Scanning Electron Microscopy to determine the morphological conditions of the powder. Result: The nanoparticle powder was brown. The total water content and ash of the extract were 0.087% and 9.672%, respectively. The characterization using PSA showed an average particle size of 306.41 nm. The SEM investigation showed that the particles morphology was uneven in surfaces, possesing irregular shapes, forming aggregates and not consistent in size. Conclusion: The nanoparticles of the ethanol extract from Rhaphidophora pinnata leaves have been prepared by using arabic gum and dextrin.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    S, S., M, M., Rusdi, I. Y., & Dalimunthe, A. (). The Preparation and Characterization of Ethanol Extract Nanoparticle from Rhaphidophora pinnata (L.f.) Schott Leaves by using Arabic Gum and Dextrin. Journal of Young Pharmacists, 10(2S), s84–s86. https://doi.org/10.5530/jyp.2018.2s.16