Ufasomes: The Symphony of Drug Delivery
Singareddy Yasaswini1, Chinthaginjala Haranath1★, Lavani Firdos1, Rompicharla Narasimha Sai1, Turubilli Satish1★ Corresponding author
- 1Department of Pharmaceutics, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, Ananthapuramu, Andhra Pradesh, INDIA.
CORRESPONDENCE
Chinthaginjala Haranath
Department of Pharmaceutics, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, Ananthapuramu, Andhra Pradesh, INDIA.
Received: 21-05-2024; Revised: 09-06-2024; Accepted: 19-07-2024.
Volume 16, Issue 4 · pp. 653–659 · PUBLISHED · DOI: 10.5530/jyp.2024.16.83
ABSTRACT
The field of ufasomes has great promise for revolutionizing drug delivery. Ufasomes have the potential to overcome limitations, enhance medicine and therapy and pave the way for future pharmacological formulations that are more effective and patient-friendly with more research and development. Ufasomes are suspensions of a closed lipid bilayer made up of fatty acids and their ionized species. They are unsaturated fatty acid vesicles with a pH range of 7-9. The primary benefit of ufasomes is that they are mostly composed of fatty acids, which allow them to readily permeate skin and exhibit systemic activity. Ufasomes demonstrate specific medication delivery. There are several kinds of preparation techniques, including vortex mixing, the autopoietic process, the round bottom flask method and thin film layer hydration. Alcohol and cholesterol are added during the preparation of ufasomes. The paper examines ufasome characteristics, pharmacokinetics, uses, advantages, disadvantages and applications. These vesicles have uses in nutrition encapsulation, drug delivery and cosmetic development.
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Yasaswini, S., Haranath, C., Firdos, L., Sai, R. N., & Satish, T. (). Ufasomes: The Symphony of Drug Delivery. Journal of Young Pharmacists, 16(4), 653–659. https://doi.org/10.5530/jyp.2024.16.83