Journal of Young Pharmacists
Volume 16, Issue 4
· pp. 607–864 · 32 articles
- Volume
- 16
- Issue
- 4
- Published
- Pages
- 607–864
- Articles
- 32
- Sections
- 4
- ISSN
- Print - 0975-1483 | Online - 0975-1505
- Journal
- JYP
In this issue
Review Article
- Review
Physical Health in Schizophrenia and Role of Clinical Pharmacist: A Narrative Review
Deepak C G, Juno Jerold Joel, Shrinivasa Undaru Bhat
pp. 607–612 · DOI: 10.5530/jyp.2024.16.78 · Published
Schizophrenia is a complex psychiatric disease with an unknown aetiology affecting the biological functions of the brain. It is a psychiatric condition affecting both genders irrespective of race, social class and reside…
- Review
Osteoporosis: Exploring Causes, Pathophysiology and Advances in Treatment: A Comprehensive Review
Vijayakumar Subash, Parimalakrishnan S, Prem Anand DC, Kaviya E, Vijayakumar AR
pp. 613–619 · DOI: 10.5530/jyp.2024.16.79 · Published
Osteoporosis diagnosis relies primarily on a clinical assessment involving the observation of signs and symptoms. The origins of this disorder may be either causative or risk-related, with some factors being preventable …
- Review
Potential of Medicinal Plants to Inhibit Neurodegenerative Activities in Diabetes: A Systematic Review
Phaik Har Yong, Wong Xue Yi, Meram Azzani, Rhanye Mac Guad, Zhi Xiang Ng
pp. 620–632 · DOI: 10.5530/jyp.2024.16.80 · Published
Several studies have established that diabetes can exacerbate the neurodegeneration process. Some studies have reported the potential use of medicinal plants to inhibit neurodegenerative activities in diabetes. Therefore…
- Review
Potential of Medicinal Plants to Ameliorate Retinopathy Events in Diabetes: A Systematic Review
Phaik Har Yong, Shirley Ling Zin Yii, Meram Azzani, Deepa Anbazhagan, Zhi Xiang Ng
pp. 633–641 · DOI: DOI: 10.5530/jyp.2024.16.81 · Published
Diabetic Retinopathy (DR) is one of the most common diabetic complications which can lead to vision loss if left unattended. Medicinal plants are considered as a treatment option for its lesser side effects. Given the ov…
- Review
Phytochemical Properties and Therapeutic Applications of Annona muricata: A Comprehensive Review
Reshma Kottila, Johnson Vimalin Hena
pp. 642–652 · DOI: 10.5530/jyp.2024.16.82 · Published
This review explores the diverse properties and applications of Annona muricata, referred to as soursop or graviola. The historical significance of medicinal herbs, particularly Annona muricata, was used in ancient medic…
- Review
Ufasomes: The Symphony of Drug Delivery
Singareddy Yasaswini, Chinthaginjala Haranath, Lavani Firdos, Rompicharla Narasimha Sai, Turubilli Satish
pp. 653–659 · DOI: 10.5530/jyp.2024.16.83 · Published
The field of ufasomes has great promise for revolutionizing drug delivery. Ufasomes have the potential to overcome limitations, enhance medicine and therapy and pave the way for future pharmacological formulations that a…
- Review
Advancements in Precision Medicine for Imaging and Pharmacotherapy in Atherosclerosis: Recent Discoveries and Emerging Technologies
Jithin Mathew, Kolathur Ragesh, Divya Gupta Palottil Kunhunni, Sreelekha Sreekumar, Anchu Chandrababu
pp. 660–666 · DOI: 10.5530/jyp.2024.16.84 · Published
Atherosclerosis is a primary factor in many cardiovascular diseases. Current treatments lack effectiveness in reducing the risk and progression of the disease, highlighting the need for better preventive measures. Precis…
- Review
Targeting Diabetic Neuropathic Pain with Flavonoids: Mechanistic Insights and Pharmaceutical Perspectives
Sajidul Hoque Ansari, Saikat Sen
pp. 667–672 · DOI: 10.5530/jyp.2024.16.85 · Published
Diabetic neuropathy is a prevalent and painful condition impacting the nervous system and a common clinical consequence of Diabetes Mellitus (DM). Effective management of various forms of Diabetic Neuropathy (DN), such a…
- Review
Hidden Plague of Thiazide Induced Hyponatremia among Elderly Patients
Akhila Eldo Parambi, Selin Chiriyankandath Joy, Mazhuvancherry Kesavan Unnikrishnan, Prashant Chandra
pp. 673–680 · DOI: 10.5530/jyp.2024.16.86 · Published
Thiazide Induced Hyponatremia (TIH) is one of the main causes of fatal hyponatremia among elderly. The global and Indian prevalence ranges from 4-14% and 30%, respectively. This paper reviewed the clinical implications o…
- Review
Caries Preventive Effect and Retention of Moisture Tolerant Resin Based and Glass Ionomer Cement Sealants: A Systematic Review
Jennifer Buela P, Jayashri Prabakar, Meignana Arumugham Indiran, Ganesh Jeevanandan, Rajesh Kumar Shanmugam
pp. 687–696 · DOI: 10.5530/jyp.2024.16.88 · Published
The traditional preventive method for treating decay often entails resin-based sealants, topical fluoride application and Glass Ionomer based sealants (GIC sealants). At present, topical fluoride application is less effe…
- Review
Targeting Glioblastoma: Advances in Precision Drug Delivery
Arunraj Tharamelveliyil Rajendran, Anoop Narayanan Vadakkepushpakath
pp. 697–705 · DOI: 10.5530/jyp.2024.16.89 · Published
Glioblastoma Multiforme (GBM) is still one of the most aggressive and resistant brain tumours, and current treatment options provide only minimal improvements in survival. Effective drug delivery is severely hampered by …
Original Artcile
- Article
Antidiabetic, Antihyperlipidemic and Protective Effect of Cupressus sempervirens L. Leaves Extract in Streptozotocin Induced Diabetic Rats
Sunayana Vikhe, Apeksha S. Fulsundar, Rahul Vikhe
pp. 706–713 · DOI: 10.5530/jyp.2024.16.90 · Published
Background:In the conventional Indian medical system, Cupressus sempervirensL., a member of the Cupressaceae family, is highly significant. C. sempervirensis a traditional medicinal plant; has been reported in the litera…
- Article
EGFR-mTOR siRNA Loaded Immumonanoparticles for Targeted Chemotherapy of Triple Negative Breast Cancer
Krishnan Shalini, Rajavel Varatharajan, Hamid Shahrul, Palanimuthu Vasanth Raj, Venugopal Vijayan
pp. 714–724 · DOI: 10.5530/jyp.2024.16.91 · Published
Background:Triple-Negative Breast Cancer (TNBC) presents a significant clinical challenge due to its aggressive nature and limited therapeutic options. A promising treatment strategy involves targeting Epidermal Growth F…
- Article
Synthesis, Molecular Docking, in silico Druglikeness: In vitro Cytotoxicity Study on MCF-7 Cell Line of Quinazolin-4-one Scaffold
Kavitha K, Jothikanth V, Kaniga P, Manoj Kumar S, Revathi P, Esakiprasanth R, Mohan S, Gowri Shankar NL, Jubilee R, Srinithi M, Lokesh Kumar H
pp. 725–734 · DOI: 10.5530/jyp.2024.16.92 · Published
Background:Quinazolinone compounds are a preferred class of multi-agent therapeutics in the domains of biology and pharmacology. One of this scaffold's most notable biological functions is its anticancer properties. Nume…
- Article
Innovative Thiophene Schiff Bases: Synthesis and Evaluation as Antitubercular Agents
Ganesh Paleti, Ashutosh Jena, Gokula Krishnu, Bharath Kumar Chagaleti, Dudhe Prashik Bhimarao, Shanthakumar Balakrishnan
pp. 735–744 · DOI: 10.5530/jyp.2024.16.93 · Published
Background:Tuberculosis (TB) is a leading airborne disease, impacting millions annually and ranking among the top ten causes of global mortality. Post-COVID-19, TB incidence has increased due to its pulmonary nature, whi…
- Article
Application of Reversed-Phase HPLC Method for the Simultaneous Determination of Lenacapavir and Bictegravir in Tablets Dosage Form
Arram Madhavi, Medidi Srinivas, Niraj Gupta
pp. 745–752 · DOI: 10.5530/jyp.2024.16.94 · Published
Background:Human Immunodeficiency Virus is a debilitating viral infection that compromises the immune system, rendering individuals vulnerable to opportunistic infections. While antiretroviral therapy can effectively man…
- Article
Dry Powder Inhaler Formulation of Remdesivir Mucoadhesive Nanoparticle for Respiratory Diseases
Venugopal Vijayan, Sengamalam Ravindran, Anbazhagan Sockalingam
pp. 753–761 · DOI: 10.5530/jyp.2024.16.95 · Published
Background:Remdesivir is a antiviral drug, which has approved in COVID-19 pandemic as emergency use. In order to solubilize the remdesivir in injection form, Sulfobutylether-Beta- Cyclodextrin (SBECD) is used as solubili…
- Article
Formulation and Evaluation of Fast Disintegrating Tablets of Antihistamine Drug Using Natural Super Disintegrants
M Mahesh, Harish K H, Fatima Sanjeri Dasankoppa, Kamaladevi Kshatriya, Rohan Latwade, Pranav Patil, Aditya Shivanand Hiremath, Agadi Hiremath Viswanatha Swamy
pp. 762–771 · DOI: 10.5530/jyp.2024.16.96 · Published
Background:Fast Disintegrating Tablets (FDTs) are crucial in pharmaceuticals for rapid drug onset and improved patient compliance, particularly for those who have difficulty swallowing. Chlorpheniramine Maleate (CPM), an…
- Article
Bioavailability Enhancement of Nebivolol Hydrochloride Loaded Transferosomes via Transdermal Route: Pharmacokinetic and Pharmacodynamic Evaluation in Rats
Saritha Dunaka, Krishnaveni Janapareddi
pp. 772–780 · DOI: 10.5530/jyp.2024.16.97 · Published
Background:Nebivolol hydrochloride is a beta blocker used to treat hypertension but has low oral bioavailability (12%) because of first-pass metabolism by CYP3A enzymes. Hence to improve bioavailability, nebivolol hydroc…
Original Article
- Article
Appropriateness Analysis of Proton Pump Inhibitor Use among General Medicine Inpatients of a Secondary Care Hospital: A Hospital Based Cross-Sectional Study
Aswathy Melel Somarajan, Balaiahgari Mani Raja Rao, Donthula Pushpa, Anke Sai Kumar, Goruntla Narayana, Venkata Ramana, Akkiraju Sudheer
pp. 781–786 · DOI: 10.5530/jyp.2024.16.98 · Published 2026
Background: Proton pump inhibitors are used for suppressing gastric acid secretion. They are among the most routinely prescribed drugs globally due to their excellent efficacy and low risk of side effects, yet they are f…
- Article
Prevalence of Sexual Side Effects in Female Psychiatric Patients Taking Psychotropic Medications: A Cross-Sectional Study
Rajesh Hadia, Vishal Singh, Nidhi Solanki, Nisheet Patel, Hemrajsingh Rajput
pp. 787–794 · DOI: 10.5530/jyp.2024.16.99 · Published 2026
Background: Many women experience sexual disorders or side effects due to factors such as age or medication use. The most common issues are lack of desire and inability to become aroused during sex. Women are more likely…
- Article
Factors Associated with Glycemic Control among Type 2 Diabetes Patients on Ayurveda Therapy
Radhika Bindu, Shashwat Nagar, Abhay Dharamsi
pp. 795–798 · DOI: 10.5530/jyp.2024.16.100 · Published 2026
Introduction: Globally, one in 10 adults is living with diabetes and nearly 40% remain undiagnosed making it a silent killer. India's traditional medical system, Ayurveda, has been practiced for thousands of years. As th…
- Article
Analyzing Lessons from Previous COVID-19 Outbreaks for Future Preparedness: A Cross-Sectional Study
Mandati Santhosh Reddy, Akul Madiwalayya Ganachari, Ramesh Bhandari, Bandaru Yeshwanth Raja, Kurubara Amaresh
pp. 799–806 · DOI: 10.5530/jyp.2024.16.101 · Published 2026
Background: The present research examines how prepared healthcare and non-healthcare professionals are to deal with the next wave of the COVID 19 pandemic outbreak and what we can take away from previous outbreaks of the…
- Article
Determining the Predictors of Vaccine Hesitancy: A Nation-Wide Study Using WHO SAGE WG Developed Vaccine Hesitancy Questionnaire
Sheba Baby John, Savitha Rajapur Sanathan, Juny Sebastian, Mandyam Dhati Ravi
pp. 807–811 · DOI: 10.5530/jyp.2024.16.102 · Published 2026
Background: Vaccine hesitancy refers to the reluctance or outright refusal to be immunized despite vaccine availability. It spans from full acceptance to complete rejection of all vaccines, with most hesitancy instances …
- Article
Assessment of Chemotherapy-Induced Peripheral Neuropathy and its Impact on Health-Related Quality of Life among Various Cancer Patients
Seethalakshmi Ravichandran, Pavithra Sasikumar, Santhosh Kumar Ganesan, Vaishnavi Karthikeyan, Jayasutha Jayram, Manickavasagam Meenakshisundaram
pp. 812–817 · DOI: 10.5530/jyp.2024.16.103 · Published 2026
Background: Cancer patients' Health-Related Quality of Life (HRQOL) could be substantially impaired by Chemotherapy-Induced Peripheral Neuropathy (CIPN). Hence, the present study is aimed to assess the prevalence of CIPN…
- Article
Assessment of Pattern of Acute Radiation Dermatitis and its Influencing Factor in Breast Cancer Patients Undergoing Radiation Therapy
Shiny Evangelin Inbaraj, Logapriya Subramanian, Sreedevi Bhaskar, Satish Srinivas Kondaveeti, Jayasutha Jayram, Harini Muralidharan, Shribhavana Jawahar
pp. 818–822 · DOI: 10.5530/jyp.2024.16.104 · Published 2026
Background: Breast cancer remains a significant global health concern and radiation therapy plays a vital role in reducing disease-related mortality and recurrence rates. However, Radiation Dermatitis (RD) is a common ad…
- Article
A Retrospective Cross-Sectional Study of Drug Utilization and Prescription Pattern in Intensive Care Unit at Multispecialty Hospital
Megha Patel, Dharti Patel, Aanal Kachhiya
pp. 823–829 · DOI: 10.5530/jyp.2024.16.105 · Published 2026
Background: Drug usage studies and prescription pattern monitoring in the Intensive Care Unit (ICU) play a pivotal role in optimizing patient care, ensuring safety, managing resources effectively, improving quality, and …
- Article
Exploring the Interplay: COVID-19 Vaccination's Influence on Long-term Symptoms and Quality of Life in Post-COVID Recovery
Yogendra Shrestha, Kantharaja Jain, Prakashkumar Doddasamiah, Stephania Joseph, Rajesh Venkataraman
pp. 830–839 · DOI: 10.5530/jyp.2024.16.106 · Published 2026
Background: More than the newly diagnosed COVID-19, healthcare systems are increasingly dealing with the complex long-term health consequences of individuals who have not entirely recovered from the SARS-CoV-2 infection.…
- Article
A Prospective Interventional Study on the Application of Lean Six Sigma DMAIC Methodology on Assessing and Improving Antimicrobial Stewardship in a Tertiary Trauma Care Hospital, Coimbatore, India
Britto Duraisingh Lourdu, Senthilkumar Palaniappan
pp. 840–851 · DOI: 10.5530/jyp.2024.16.107 · Published 2026
Background: Antimicrobial stewardship is referred as a concerted endeavor to ensure proper usage of antibiotics and deviations in programme leads to inappropriate use of antimicrobials, hence it requires standard tool to…
Case Report
- Article
Transverse Leukonychia (Mees Lines) in Pediatric T-cell Acute Lymphoblastic Leukemia a Rare Manifestation During Combination Chemotherapy’s Maintenance Phase: A Case Report
Manjula Gudhoor, Shreeta Kumaresh, Abhilasha Sampagar, Ashwini Doddannavar, Gangayya Wakkundmath, Pratiksha Kini
pp. 852–855 · DOI: 10.5530/jyp.2024.16.108 · Published 2026
An array of clinical manifestations, majority of which are relevant to dose and fade away after drug discontinuation, may accompany drug-induced nail abnormalities, but rarely do they endure over a long time. However, on…
- Article
Validation of Siddha Medicine in the Treatment of Alopecia areata in Paediatric Patient: A Case Report
Preetheekha Elangovan, Gomathi Ramaswamy, Subathra Thangamani, Mamallan Arumugam, Priyadharshini Ananthathandavan
pp. 856–860 · DOI: 10.5530/jyp.2024.16.109 · Published 2026
Alopecia Areata (AA) is an autoimmune condition characterized by scattered patches of hair loss on the body and scalp. Hair loss can be a cause of psychological stress and sufferers may suffer from social phobia, anxiety…
- Article
Darier Disease: A Case Report with Psychiatric Involvement
Anusha Rao, Shristi Reddy, Prasannakumar C Bullapur, Shamita Shyam Sail, Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy
pp. 861–864 · DOI: 10.5530/jyp.2024.16.110 · Published 2026
This case report outlines the clinical presentation and management of a 35-year-old female diagnosed with Darier disease, a rare autosomal dominant disorder resulting from an ATP2A2 gene mutation. The patient's atypical …