Journal of Young Pharmacists
Volume 17, Issue 1
· pp. 1–245 · 33 articles
- Volume
- 17
- Issue
- 1
- Published
- Pages
- 1–245
- Articles
- 33
- Sections
- 4
- ISSN
- Print - 0975-1483 | Online - 0975-1505
- Journal
- JYP
In this issue
Review Article
- Review
Biomarker of Vitiligo: A Review Update
Rohit Agrahari, Gunosindhu Chakraborthy, Rakhi Mishra
pp. 1–6 · DOI: 10.5530/jyp.20251485 · Published
The pathophysiology of vitiligo is very complex. It is an autoimmunity disease that cause white patches on the skin basically when decrease the melanin production in our body then they cause the skin depigmentation. High…
- Review
Navigating Effective Therapeutic Strategies for Dermatophytosis
Mohammed Gulzar Ahmed, Prajitha Biju, Manjunath M Shenoy, Abdul Rehaman Shafeeh, Mohammed Mustafa, Samaru Samaru, Saptami Kanekar, Zakiya Fathima
pp. 7–12 · DOI: 10.5530/jyp.20251259 · Published
Dermatophytosis, a common fungal skin infection, is a pressing global health issue, especially in underdeveloped regions where resistance to all antifungal classes is prevalent. While tinea infections are superficial, th…
- Review
Systematizing PDE4 Inhibition in Psoriasis Treatment: Roflumilast Leads the Way
Remya Ravindran, Palayyan Muralidharan, Arulkumaran Govindarajan
pp. 13–18 · DOI: 10.5530/jyp.20251506 · Published
Psoriasis, a prevalent autoimmune disorder, presents significant challenges due to its chronic inflammatory nature and multifactorial etiology, involving both genetic tendency and environmental factors. Conventional ther…
- Review
Exploring the Use of Herbal Medicines in the Context of Dermatokinetic Research
Sakshi Ingale, Jaishriram Rathored, Sanjana Wankhade, Sakshi Nibude
pp. 19–25 · DOI: 10.5530/jyp.20251326 · Published
Herbal therapy is the application of herbal remedies to prevent and treat illness. It encompasses a variety of practices, from the use of standardized and treated herbal extracts to traditional and popular medicines used…
- Review
The Impact of Novel Purine, Pyrimidine and Folate Analogues on Cancer Treatment: A Review
Jayashree Kallukombari Ramakrishna, Padma Shree Kotebetta Ramakrishne Gowda, Abdul Rahamanulla, Purushotham Karadigere Nagaraju, Bevinahalli Ramesh, Manojmouli Chandramouli
pp. 26–35 · DOI: 10.5530/jyp.20251471 · Published
The primary goal of this review is to highlight the anti-cancer activity of class of Anti-metabolites derivatives particularly emphasizing purine, pyrimidine and pteridine/folate antagonists as chemotherapeutic agents. T…
- Review
Novasomes: A Versatile Drug Delivery System for Enhanced Therapeutic Efficacy
Muhammad Abid Mustafa, Namra Rasheed, Maryam Ayesha, Qurat ul Ain, Maryam Mughal, Muhammad Fahad, Hamda Shakir, Ansa Ijaz, Muhammad Ali Tahir, Meer Muhammad, Moiz Ali, Areej Kainat
pp. 36–45 · DOI: 10.5530/jyp.20251440 · Published
Novasomes, a new drug carrier developed by Novavax, offers enhanced absorption and reduced side effects compared to traditional forms. These multilayered vesicles, with a diameter of 200-700 nm, maintain stability across…
- Review
Zinc Oxide Nanoparticles for their Anti-Convulsant Property: A Comprehensive Review
Aishwarya Venkatesh, Bharathi Doddla Raghunathanaidu, Chandan Kumar, Jayanth Baburayanakoppal Manchegowda, Syed Sagheer Ahmed
pp. 46–53 · DOI: 10.5530/jyp.20251354 · Published
Zinc Oxide Nanoparticles (ZnO NPs) have garnered interest for their potential anti-convulsant properties, offering a promising approach to epilepsy treatment. Their unique physicochemical traits, such as a large surface …
- Review
Recent Advances in Intranasal Delivery with Lipid Nanoparticles for Brain Targeting: A Review
Isha Sidhaye, Ameet Karadagi, Harish K H, Vijaykumar Meti, Fatima Sanjeri Dasankoppa, Agadi Hiremath Viswanatha Swamy
pp. 54–61 · DOI: 10.5530/jyp.20251166 · Published
Psychological or behavioural tendencies that significantly impair one or more key areas of functioning or cause significant distress are considered psychological disorders. Psychological disorders exist in a wide variety…
- Review
A Systematic Review: Antihyperglycemic Properties of Catharanthus roseus Linn.
Keyur Dudhat, Anita Wanjari, Elijah Skarlus Doelakeh
pp. 62–69 · DOI: 10.5530/jyp.20251394 · Published
Background:Diabetes mellitus is a term for several diseases that affect how your body regulates blood sugar. Ayurveda has long used Catharanthus roseusLinn., to cure diabetes. This review aims to summarise existing scien…
- Review
ROS-Mediated NLRP3 Inflammasome Activation in the Progression of Hypertensive Nephropathy and its Therapeutic Interventions
Bader Alsuwayt
pp. 70–78 · DOI: 10.5530/jyp.20251476 · Published
Among many molecular and cellular level elements which are involved in the development of hypertension, generation of reactive oxygen species not only involved in the pathogenesis of hypertension but also contribute to t…
Original Artcile
- Article
Procedural Document Control in the Pharmaceutical Industry
Renee Moorefield
pp. 79–85 · DOI: 10.5530/jyp.20251400 · Published
Background:Procedural documents such as Standard Operating Procedures (SOPs) are core elements of the pharmaceutical industry for all GxP, or good practice, environments such as GCP (good clinical practice) and GMP (good…
- Article
Assessment of the Level of Satisfaction with Online Teaching and Learning among Faculty and Students at Selected Health Sciences College, Puducherry
Sumathy Ponnambalam, Sherin Nithya Suria Prakash
pp. 86–88 · DOI: 10.5530/jyp.20251338 · Published
Background:The COVID 19 pandemic lock down forced educational institutions to shut down and amid this is the new reality-online teaching learning that emerged as a potent tool to support the crisis. However, medical inst…
- Article
Phyto-chemicals and Spectral Characterization of Novel Glaucarubinone Quassinoid from Simarouba glauca Leaves: In vitro Anti-proliferative Potential against Breast Adenocarcinoma Cell line
Vanitha Subburaj, Umaa Kuppuswamy, Veintraimuthu Sankar
pp. 89–96 · DOI: 10.5530/jyp.20251210 · Published
Background:Simarouba glaucabelonging to the Simaroubaceae family and rich in quassinoids was traditionally used to treat cancer. Our aim is to quantify quassinoid in its leaf’s bioactive extract and perform in vitroscree…
- Article
Comparative Analysis of Secondary Metabolites and Anxiolytic Effects in Hydroponic and Soil-Grown Basil (Ocimum basilicum)
Mayur Porwal, Mukesh Singh Sikarwar, Om Kar
pp. 97–104 · DOI: 10.5530/jyp.20251509 · Published
Background:This study compares two different agricultural systems in order to identify the most effective basil crop that meets present and future demand at lower expenses and resource use. The major types of basil plant…
- Article
Hepatoprotective Effect of Whole Plant Powder Leucas aspera Spreng
Shilpa Hiremath, Pradeep Pradeep, Sunil Kumar KN
pp. 105–112 · DOI: 10.5530/jyp.20251286 · Published
Background:In recent years plant origin drugs have gained more popularity as hepatoprotective agents owing to their safety, low-cost and efficacy and thus for safe hepatoprotective agents will be having an ever-increasin…
- Article
Antibacterial and Antifungal Activities of Mercury Based Traditional Siddha Herbo-Metallic Formulation Mega Sanjeevi Mathirai against Selected Urogenital Pathogens
Siva Annamalai, Jayaveeran Thavaseelan, Deepa Ravichandran, Sathya Rathish Mohana Jeevanath, Suresh Ramasamy, Elamathi Srinivasan, Anbarasan Balasubramaniyan
pp. 113–122 · DOI: 10.5530/jyp.20251413 · Published
Background:Urinary Tract Infection (UTI) is referred as an infection of any part of the genitourinary tract and is more prevalent in women due to biological predisposition. Escherichia coliis a common causative organism.…
- Article
Isolation and Characterization of Renal Protective Compounds from Orthosiphon stamineus Leaves: A Traditional Medicinal Plant
Venkatesan Natarajan, Pradeepraj Devarasu, Aravinth Velmurugan, Thamizh Senthamarai Kannan
pp. 123–129 · DOI: 10.5530/jyp.20251477 · Published
Background:Orthosiphon stamineus, also known as "cat’s whiskers," is traditionally used in several Asian countries, including India, China, Malaysia, and Thailand, for managing conditions like diabetes and chronic renal …
- Article
Molecular docking Toxicological profile, Antioxidant and Antidiabetic Potential of Hydroalcoholic Extract of Leaves of Euphorbia indica (Lam.) from Saudi Arabia
Sridevi Chigurupati, Salma Abdulrahman Alolayan
pp. 130–137 · DOI: 10.5530/jyp.20251452 · Published
Background:The present research predominantly aimed at the molecular docking, toxicological profile, antioxidant, and antidiabetic testing of Euphorbia indicaleaves extract. Materials and Methods:Euphorbia indicaLeaves E…
- Article
Synthesis, in silico and Pharmacological Activity of 1, 3-Benzothiazol Derivatives
Rinchi Bora, Durga Prasad Kemisetti, Faruk Alam, Alindam Ghosh, Avik Dutta, Sarbani Roy, Moidul Islam Judder
pp. 138–148 · DOI: 10.5530/jyp.20251339 · Published
Background:Benzothiazole and its derivatives serve as a unique and versatile moiety for experimental drug design, especially in pharmaceutical chemistry, because of their potent pharmacological activities. Hence, the pre…
- Article
Design, Synthesis and Evaluation of Substituted Benzimidazoles as Potent Polyketide Synthase 13 Inhibitors for Tuberculosis
Gokula Krishnu, Ganesh Paleti, Bharath Kumar Chagaleti, Ahmed Mueen, Shanthakumar Balakrishnan
pp. 149–159 · DOI: 10.5530/jyp.20251380 · Published
Background:Tuberculosis remains a major global health concern, affecting millions of lives annually due to its high morbidity and mortality rates. The urgent need for effective treatments has driven research into novel t…
- Article
Anti-Acne Activity of Minocycline Hybrids
Mansi Shah, Bhanubhai Suhagia, Sunita Goswami, Arpit Patwari
pp. 160–165 · DOI: 10.5530/jyp.20251401 · Published
Background:The Propionibacterium acnes(P. acnes) has been the most abundant acne causing bacteria on human skin. Tetracyclines and macrolides have been used against this bacterium. A need to develop newer antibiotics has…
- Article
Spontaneous Emulsification as a Novel Approach for the Preparation and Characterization of Curcumin Nanoemulsion: Advancing Bioavailability and Therapeutic Efficacy
Joshna Booravilli, Janaki Devi Sirisolla
pp. 166–175 · DOI: 10.5530/jyp.20251414 · Published
Purpose:Curcumin is a phytochemical that is bioactive and exhibits strong therapeutic effects on several skin diseases. Curcumin's (CUR) low water solubility and restricted skin permeability constitute a major obstacle t…
- Article
Formulation and Evaluation of Phytosomes Loaded Polyherbal Gel for Pharyngitis
Vandhana Vijayakumar, Thirumalaikumaran Rathinam, Sharan Raj Rajmohan, Kowsik Elumalai
pp. 176–186 · DOI: 10.5530/jyp.20251325 · Published
Background:Sore throat, or pharyngitis, is a common viral or bacterial infection. Conventional drug delivery techniques may not target inflamed areas due to their lack of specificity. To enhance treatment efficacy, impro…
- Article
Formulation and Evaluation of Retinoic Acid Loaded Quatsomes for Topical Application
Asiya Abdul Ali, Keerthana Raja, Pavithra Soundarapandi, Sanjai Sakthivel, Vijayan Venugopal
pp. 187–193 · DOI: 10.5530/jyp.20251558 · Published
Background:This study aimed to develop and characterize quatsomes as a novel nanocarrier system for the delivery of retinoic acid in keloid treatment. Materials and Methods:Three quatsomes formulations (F1, F2 and F3) wi…
- Article
Clinical Implications of Premature Rupture of Membranes in Gestational Women in a Tertiary Care Hospital: A Prospective Observational Study
Tejashree Sridhar, Sudhanshu Shukla, Neeraj Hiremath, Leena Elizabeth Varghese, Agadi Hiremath Viswanatha Swamy, Jayasheela Siddhalingayya Hiremath, Sanatkumar Bharamu Nyamagoud
pp. 194–200 · DOI: 10.5530/jyp.20251175 · Published
Background:Preterm Premature Rupture of Membranes (PPROM) is a leading cause of newborn morbidity and mortality. The purpose of our research is to evaluate the clinical implications of PPROM in pregnant women, with a par…
- Article
Impact of Widal Test Interference on Hemoglobin Levels in Typhoid Fever
Jayanta Deb, Saurabh Gupta, Tapan Majumdar
pp. 201–205 · DOI: 10.5530/jyp.20251424 · Published
Background:Salmonella typhiis the cause of enteric fever and typhoid disease. Due to the lack of clean drinking water and poor hygiene standards, it is most commonly found in underdeveloped countries. The infection's mos…
- Article
Drug Utilization Evaluation in Upper Respiratory Infection in Pediatric Population in North Indian Tertiary Hospital
Ritesh Rauniyar, Raju Kumar Mandal, Rupa Joshi, Rishabh Chaudhary, Seema Bansal, Ashwani Kumar Sood, Tarun Singh
pp. 206–212 · DOI: 10.5530/jyp.20251422 · Published
Background:According to the WHO, around 5 million childhood deaths occur per year and around 20% of all childhood deaths are due to acute respiratory tract infections. Materials and Methods:A cross-sectional study was ca…
- Article
An Observational Study on Assessing the Safety and Efficacy of Tenecteplase for Door-To-Needle Time Acute Ischemic Stroke Patients
Aswathee Sivakumar, Balaprasath Balaji, Abin Benny, Boobalan Ramalingam, Dhanu Veera Pandian, Arun Shivaraman, Sengottuvelu Singaravel, Sheik Haja Sherief, Sivakumar Thangavel
pp. 213–218 · DOI: 10.5530/jyp.20251493 · Published
Background:Stroke is a significant burden in India which is a leading cause of death globally. This study aimed to evaluate the Safety and Efficacy of Tenecteplase for Acute Ischemic Stroke patients who arrived within 3.…
- Article
Quality Evaluation of Dermatology Prescriptions: Completeness, Legibility and Rationality in a Tertiary Care Indian Hospital
Amang Kipa, Sahwney Mohinder Pal, Setya Sonal
pp. 219–225 · DOI: 10.5530/jyp.20251456 · Published
Background:Illegible, incomplete and inappropriate prescriptions can lead to medication errors and adverse drug reactions. Dermatological conditions, despite their global prevalence, are often underestimated. This study …
- Article
Cardiovascular Disease Prediction Using Machine Learning Metrics
Aashish Gnanavelu, Champa Venkataramu, Ramakrishna Chintakunta
pp. 226–233 · DOI: 10.5530/jyp.20251231 · Published
Background:This project aims to develop a Machine-Learning model for heart disease prediction based on clinical and demographic data. Traditional diagnostic methods may not always detect subtle risk factors, hence Machin…
- Article
Histopathological Variation on Testis of Sex Reassignment Surgery (SRS) Transgenders on Hormonal Therapy
Preetha Devi Naval Boopathy, Siva Kaliyamoorthy, Uma Arumbuliyur Natarajan
pp. 234–238 · DOI: 10.5530/jyp.20251268 · Published
Background:The purpose of this study was to investigate whether the histopathology of the male transsexual's testis could provide insight into the causes of male transsexualism. Hence, the present study is to planned to …
Short Communication
- Communication
Impact of Siddha Medical System among the Tribal Populations of Mokokchung, Nagaland, India
Samraj Karunanithi, Eugene Wilson
pp. 239–242 · DOI: 10.5530/jyp.20251343 · Published
Background:The Siddha Medical System, originating from South India, was introduced in Nagaland to assess its efficacy, strength, and affordability. The Ministry of AYUSH (Ayurveda, Yoga, Naturopathy, Unani, Siddha, and H…
Case Report
- Article
A Case Report on Dermatomyositis Highlighting Muscle Weakness and Rash
Raj Ahmad Rain, Titli Bhattacharjee, Prayushi Patel, Mohit Badhai, G Anil Kumar Reddy
pp. 243–245 · DOI: 10.5530/jyp.20251372 · Published
The disorder is known as Dermatomyositis, a rare autoimmune condition characterized by inflammation of the muscles and specific types of skin rashes. The case report presents a 33-year-old woman with hypothyroidism that …