Volume 17, Issue 2

The Binocular Rivalry: The Phenomenon of Interocular or Perceptual Competitions?

Mohammed Nazrul Islam, Farhan K. Alswailmi, Mujeeb Ur Rehman Parrey, Ashfaq Ahmad

pp. 246–249 · DOI: 10.5530/jyp.20251616 · Published

We see the magnificence of the nature through our two bare eyes, albeit due to image coherence at the retina, we normally perceive only one sight at a time. That is, monocular stimuli get merged into a single visual impr…

Unveiling the Cardiovascular-Guarding Secrets of Phoenix dactylifera: A Systematic Review

Thippeswamy Boreddy Shivanandappa, Ghallab Alotaibi, Maheswari Chinnadhurai, Sudharshan Reddy Dachani, Mahmad Dabeer Ahmad, Khalid Abdullah Aldaajanii

pp. 250–263 · DOI: 10.5530/jyp.20251656 · Published

Cardiovascular disease is a significant cause of global mortality, creating a substantial burden on public health and economy. Research focusing on beneficial food and its active ingredients is essential to mark the heal…

Unveiling the Power of Vitamin D: Key Insights into its Role in Health

Snehal Joshi, Rajesh A. Maheshwari

pp. 264–270 · DOI: 10.5530/jyp.20251662 · Published

Vitamin D, often called the "sunshine vitamin," is essential for various physiological processes and overall health, produced in the skin through UVB exposure and obtainable from food and supplements. It regulates calciu…

Effects of Phytoconstituents on Adipocytes in the Management of Obesity and Hyperinsulinemia

Mukesh Singh Sikarwar

pp. 271–278 · DOI: 10.5530/jyp.20251634 · Published

Obesity and overweight are the risk factors for Type 2 diabetes. Obesity is also linked to non-communicable diseases like dyslipidemia, hypertension, and cardiovascular diseases. Adipocyte precursor cells are multiplied …

Nanosponges: An Emerging and Promising Strategy in Drug Delivery

Dhanush Ramesh Gandhi, Kuppusamy Sujatha, Cherukuri Sowmya

pp. 279–291 · DOI: 10.5530/jyp.20251483 · Published

Nanosponges (NSs) are a novel class of nanomaterials that have garnered substantial interest due to their unique properties and potential applications in drug delivery. The primary objective of this review is to provide …

The Impact of Metformin on Neurological and Metabolic Function through Gut Microbiota

Sheik Musharaf, Mohammed Fayaz, Priyadharshini Ananthathandavan

pp. 292–298 · DOI: 10.5530/jyp.20251539 · Published

Metformin is an oral hypoglycemic agent and it is the primary medication for managing hyperglycemia. The relationship between metformin, gut microbiota and their combined effects on metabolic health and cognitive functio…

A Focus on Cystic Fibrosis Transmembrane Regulator (CFTR) Genetic Lesions, Phenotype Expressions and Emerging Therapies for Cystic Fibrosis: An Update

Shaik Karimulla

pp. 299–305 · DOI: 10.5530/jyp.20251508 · Published

Cystic Fibrosis (CF) is a multisystem disorder primarily impacting the lungs, characterized by bronchial obstruction, infection and inflammation. Over 75% of CF patients are diagnosed by age 2, with most living beyond 18…

From Bench to the Heart: Metal-Based Complexes and Nanoparticles as Pioneers in Cardio-Protection and Cardiovascular Management

Esraa Mohammad Haji

pp. 306–318 · DOI: 10.5530/jyp.20251663 · Published

Cardiovascular Disorders (CVDs) are the leading cause of mortality and disability worldwide. Nanotechnology involving metal complexes as drug delivery systems is gaining attention for its cardioprotective potential. This…

Stability Indicating Simultaneous Quantification of Chlorogenic Acid and Berberine in Homeopathic Polyherbal Formulation by AQbD Based HPLC

Kalyani Kasetti, Sailaja Bandhakavi

pp. 319–328 · DOI: 10.5530/jyp.20251556 · Published

Background:Analytical Quality by Design (AQbD) enhances method robustness more effectively than traditional methods. Risk assessment and factor screening studies enabled to detection of analytical method parameters. The …

Development of Microemulsion of Marjoram Oil in the Line of Treatment of Otitis Media

Avinash Balasaheb Gangurde, Vaibhav Sudam Pandit, Kranti Ashok Suryawanshi, Bhagyashri Vijay Soundane, Sandesh Ragho Nikam, Parag Ashok Pathade

pp. 329–335 · DOI: 10.5530/jyp.20251347 · Published

Background:Marjoram oil, an antimicrobial agent, has significant potential for industrial applications due to the presence of a high proportion of chemical components such as terpinene-4-ol, sabinene hydrate, thymol, and…

Formulation and Evaluation of Polyherbal Pain Relief Gel for its Effect on Rheumatoid Arthritis

Bratati Bandyopadhyay, Arif Munsi, Kabirul Islam Mollah, Biplab Debnath, Amlan Bishal

pp. 336–343 · DOI: 10.5530/jyp.20251472 · Published

Background:Almost 1-3% of people worldwide suffer from arthritis. It is an autoimmune disease that can harm extra-articular organs in addition to joints. Rheumatoid arthritis is commonly treated with steroidal, non-stero…

Comprehensive Study on the Pharmacognostical, Physico-Phytochemical, and Analytical Properties of Citrus limon (L.) Burm. F. Fruit

Punam Aggarwal, Vishal Kumar, Renjini Haridas, Divyani Singh, Swapnil Chaudhari, Galib Ruknuddin

pp. 344–352 · DOI: 10.5530/jyp.20251605 · Published

Background:Pharmacognosy is a scientific and systematic study of natural products helps in identification of raw material through morphological and chemical properties. Citrus limon(L.) Burm. f. is a tree, and its fruits…

Exploring the Potential of 5-HT1 Receptor Subtypes as Therapeutic Targets for Obesity Treatment in Animal Models

Navpreet Kaur, Puja Gulati

pp. 353–358 · DOI: 10.5530/jyp.20251548 · Published

Background:Serotonergic system plays an important role in the energy balance evidenced by various studies. The present study was designed to investigate the involvement of 5-HT1 receptor subtype in experimental obesity. …

Exploring the Combined Effects of Vitamin D and Pioglitazone on Lipid Dysregulation, Hepatic Function, and Adipocytokine Alterations in Type 2 Diabetic Rats

Snehal Joshi, Rajesh A. Maheshwari

pp. 359–364 · DOI: 10.5530/jyp.20251598 · Published

Background:This study assessed the effects of Vitamin D (Vit D) and Pioglitazone (PIO) on metabolic and histopathological parameters in STZ-NA-induced diabetic rats, focusing on lipid metabolism, liver enzymes, adipocyto…

Randomized, Multicentric Parallel-Group Clinical Trial of the Herbo-Mineral Formulation T-AYU-HM Premium in Patients with Sickle Cell Anemia: A Prospective Study

Atul Desai, Kavita Desai, Hemshree Desai, Chirag Desai

pp. 365–375 · DOI: 10.5530/jyp.20251606 · Published

Background:Sickle Cell Anemia (SCA) is a hereditary blood disorder that significantly impacts the quality of life of those affected. While conventional treatments do have improved patient outcomes, they frequently fall s…

Incidence of Steroid-Induced Cushing Syndrome, its Treatment Outcome and Influence on Quality of Life in Primary Brain Tumor Patients Receiving Radical/Adjuvant Radiation Therapy

Haritha Ramesh, Sindhu Selvam, Pravin Kumar Muthukumaresan, Silviya Jenifer John Bosco, Satish Srinivas Kondaveeti, Jayasutha Jayram, Venkatesan Singaram

pp. 376–379 · DOI: 10.5530/jyp.20251567 · Published

Background:Steroids are more commonly used in the treatment of tumor-induced edema in primary brain tumor patients receiving radiation therapy. Steroid-induced Cushing syndrome is one of the adverse effects of steroid th…

Cross-Sectional Observational Study on Medication Adherence Levels among Patients with Hypertension in Community Settings of Coastal Districts of Andhra Pradesh

Supriya Rayana, Rajeshwari Pasupula, Arra Keerthana, Grandhi Kavya Sruthi, Maddu Naga Suvarna, Shaik Mohammad Noor, Pucha Jahnavi Naga Pavani, Manaswini Pedapudi, Gummadavalli Sravani, Blessy Chittelu

pp. 380–386 · DOI: 10.5530/jyp.20251276 · Published

Background:Poor medication adherence can significantly reduce treatment efficiency and impact clinical outcomes, ultimately hindering the effectiveness of patient care. Non-adherence to anti-hypertensive medication is a …

Assessing the Impact of Broad-Spectrum Antibiotics on Fungal Infection Rates in ICU Patients: Implications for Patient Safety

Rajesh Hadia, Amit Chauhan, Bineet Thakkar, Damini Patel, Mariya Bagban, Hemraj Singh Rajput

pp. 387–393 · DOI: 10.5530/jyp.20251356 · Published

Background:Invasive Fungal Infections (IFIs) are on the rise, notably among critical care patients in the Intensive Care Unit (ICU) undergoing treatment with Broad Spectrum Antibiotics (BSAs). These antibiotics, designed…

A Comparative Study on Assessment of Empiric Antibiotic Susceptibility Rates between Traditional and Syndromic Antibiogram

Dhivya Kothandan, Sethumeena Singaram, Hanusha Venkatesan, Aswini Sankar, Shyam Sundar Subramanian, Lakshmi Priya Arul, Nandhani Nandagopal, Bala Abirami Mugunthan

pp. 394–399 · DOI: 10.5530/jyp.20251540 · Published

Background:Antibiogram serves as a crucial tool for providing guidance in empiric therapy. Most of the hospitals rely on Traditional Antibiograms (TA) for prescribing antibiotics. But recognizing the importance of Syndro…

Blood Pressure Variability in Different Siting Postures in Correlation with Body Mass Index

Sherly Deborah George, Felix Tan Yee Shuen, Usha Kumari, Theingi Maung Maung

pp. 400–405 · DOI: 10.5530/jyp.20251639 · Published

Background:Blood Pressure (BP) variability is a crucial yet often overlooked factor in cardiovascular health, reflecting the dynamic nature of cardiovascular regulation in response to various stimuli. Among the factors i…

Assessing Public Awareness of Gout and the Health Implications of High Red Meat Consumption in Saudi Arabia; A Cross-Sectional Study

Meshal Alotaibi

pp. 406–411 · DOI: 10.5530/jyp.20251619 · Published

Background:Gout is a prevalent form of inflammatory arthritis characterized by elevated uric acid levels, often influenced by dietary habits, particularly red meat consumption. Understanding public knowledge and awarenes…

Bridging the Adherence Gap: Innovative Counseling Strategies and their Effect on HbA1c in Type 2 Diabetes Patients

Ninad Bharat Patil, Pradnya Prakash Patil, Narendra Javadekar, Sunita Pawar

pp. 412–419 · DOI: 10.5530/jyp.20251682 · Published

Background:Medication adherence is essential for effective Type 2 Diabetes Mellitus (T2DM) management; still, non-adherence occurs in countries with low or middle incomes like India, leading to uncontrolled glycemia and …

Dispensing Practices of Antibiotics among Community Pharmacies of Bharatpur, Nepal: A Simulated Patient Cross-Sectional Study

Pooja Rimal, Anil Kumar Sah, Kadir Alam, Mukhtar Ansari, Khalid Omar Alshaghdali, Rajesh Kumar Jha

pp. 420–426 · DOI: 10.5530/jyp.20251698 · Published

Background:The practice of community pharmacies dispensing antibiotics without a prescription is widespread, and improper use of these medications is associated with the emergence of resistance. Hence, this study aimed t…

Utilization of Complementary and Alternative Medicine (CAM) among Chronic Disease Patients in a Government Hospital Outpatient Department in Hyderabad

Sobia Noor, Afrah Begum, Sidra Amara Siddiqua, Ghouse Qhasim Maula Bakshi

pp. 427–433 · DOI: DOI: 10.5530/jyp.20251572 · Published

Background:Complementary and Alternative Medicine (CAM) use is prevalent among patients with Non-Communicable Diseases (NCDs). Understanding the factors driving CAM use in this population is essential for improving chron…

Morbidity Profile of Patients Attended Siddha Cancer Special OPD of Arignar Anna Government Hospital of Indian Medicine, Chennai: A Cross-Sectional Study

Barathi Kannamma Govindarasu, Samooga Neethi Jaganathan, Venthamarai Selvi Jayaprakash Narayanan, Kanakavalli Kadarkarai, Parthiban Panner Selvam

pp. 434–441 · DOI: 10.5530/jyp.20251638 · Published

Background:As recommended by World Health Organization, Traditional and Complementary Medicines should be mainstreamed to manage and prevent chronic diseases, one such deadly chronic disease is Cancer. Hence, this study …

A Prospective Observation Study on Medication Errors among Surgical Gastroenterology In-Patients in Tertiary Care Hospital

Gagguturi Karishma, Sheik Bushra, Pallam Priya, Devaki Kondaveeti, Jeevan Kumar Badvel, Nithya Settipalli, Revanth Yadav Nellepalli, Sravani Thommandru, Kamati Mounika, Rohith Chandra

pp. 442–446 · DOI: 10.5530/jyp.20251653 · Published

Background:A Medication Error (ME) is a preventable adverse event in medical treatment. The main objective of the study is to classify, categorize, evaluate, monitor, and assess the severity of medication errors and repo…

Appropriateness of Topical Corticosteroids Usage in Dermatology Patients of a Tertiary Care Hospital

Sreeraj Kandoth, Rompicherla Narayana Charyulu, Sarath Chandran Chadrashekar Shenoy, Uday Venkat Mateti, Juno Jerold Joel, Sarin S M

pp. 447–453 · DOI: 10.5530/jyp.20251787 · Published

Background:Topical Corticosteroids (TCs) have been a cornerstone in the management of various dermatological conditions. The dual nature of their widespread use and potential for misuse has emerged as a significant conce…

Spectroscopic Determination of Glimepiride and Linagliptin in Combined Synthetic Blends

Tandel Prexa, Patel Ayushi Shaileshbhai, Mehta Hiralben Satishchandra

pp. 454–462 · DOI: 10.5530/jyp.20251706 · Published

Background:Glimepiride along with Linagliptin have been commonly utilized in combination for treatment of type 2 diabetes mellitus. For routine analysis and quality control, it is essential to develop a straightforward, …

Clinical Profiles, Prescription Trends, and Quality of Life in Young Adults with Acne Vulgaris: A Cross-Sectional Study in a Tertiary Care Teaching Hospital

Rajesh A. Maheshwari, Shruti Makwana, Harshad Sisara, Hemraj Singh Rajput, Rahul Trivedi, Ashim Kumar Sen, Kishan Ninama

pp. 463–469 · DOI: 10.5530/jyp.20251592 · Published

Background:This study aimed to analyze the demographic distribution, acne characteristics, treatment patterns, and quality of life impact of acne vulgaris. Materials and Methods:A cross-sectional study was conducted at a…

In vitro Anti-Urolithiatic Evaluation of a Polyherbal Formulation against Calcium Oxalate-Induced Urolithiasis in Rats

Subhranshu Panda, Nikhil Chakravarthy Erigi, Tharun Kumar Gaddapuram

pp. 470–476 · DOI: 10.5530/jyp.20251729 · Published

Background:Kidney stones form due to the crystallization of minerals and salts in the urinary tract. Despite advancements in understanding their pathophysiology, treatment options remain expensive and often lead to recur…

Effect of Sertraline in Newly Diagnosed Depression Patients with Post MI and Stroke: A Prospective Cohort Study

Varshasneha Kumar, Ashok Sriram NK, Natarajan Shanmugasundaram, Nithishadevi Pannirukai Selvan, Deepthi Munirathinam, Jaysreedharshini Pillai, Kaviya Srinivasan, Karthik Sankar

pp. 477–482 · DOI: 10.5530/jyp.20251651 · Published

Background:Depression is a condition that affects mental health defined by persistent feelings of sadness and reduced interest in daily activities. Myocardial Infarction (MI) and stroke significantly contribute to global…

Are the Newer Phytochemicals Effective in the Treatment of Cancer?

Sanjib Bhattacharya

pp. i–ii · DOI: 10.5530/jyp.20250001 · Published