Volume 17, Issue 3

· pp. 483–751 · 33 articles

Volume: 17
Issue: 3
Published
Pages: 483–751
Articles: 33
Sections: 3
ISSN: Print - 0975-1483 | Online - 0975-1505
Journal: JYP

Review Article Original Artcile Case Report

In this issue

Review Article

Review
Natural Compounds as Inhibitors of Advanced Glycation End Products Formation: A Systematic Review
Phaik Har Yong, Ng Soon Kee, Meram Azzani, Deepa Anbazhagan, Zhi Xiang Ng
pp. 483–494 · DOI: 10.5530/jyp.20251697 · Published
Diabetes and related complications are becoming the leading causes of death in the world. In Malaysia, there are around 3.4 million of people affected by diabetes. Long-term diabetes can lead to the development of variou…
Review
Transbuccal Drug Delivery Systems: A Comprehensive Review of Recent Approaches
Kumara Swamy Samanthula, Agaiah Goud Bairi, Daniel Kothapally
pp. 495–503 · DOI: 10.5530/jyp.20251309 · Published
In recent decades, there has been a growing fascination with delivering therapeutic agents through transmucosal (buccal, sublingual, nasal, rectal, and vaginal) drug delivery systems. Drug delivery through oral transmuco…
Review
Liquid Chromatographic Techniques for the Qualitative and Quantitative Analysis of Cyclosporine and Gingerol: Advances in Rheumatoid Arthritis Management
Priyanka Kotla, Rashmi Nelligare Gopalkrishna
pp. 504–510 · DOI: 10.5530/jyp.20251790 · Published
This review focuses on the advancements in liquid chromatographic techniques to do both qualitative and quantitative research on cyclosporine and gingerol, with particular emphasis on their incorporation into Novel Drug …
Review
Insights on Sjögren's Syndrome: Beyond Dry Eye Symptoms
Debasis Patra, Kirtimaya Mishra, Asra Jabeen, Prasanna Parida, Abhilash Dash, Gowri Sankar Chintapalli, Diptimayee Jena
pp. 511–519 · DOI: 10.5530/jyp.20251687 · Published
Sjögren's Syndrome (SS), a systemic autoimmune condition, that is characterised by the presence of dry eyes along with dry mouth. However, it is important to note that the effects of this disorder are not limited to thes…
Review
Understanding the Post-COVID Cardiovascular Impact: Manifestations, Prevalence, and Clinical Evaluation
Deepak Kumar Jha, Darshan Rajashekhar
pp. 520–531 · DOI: 10.5530/jyp.20250012 · Published
There is growing evidence highlighting a significant risk of cardiovascular complications in patients recovering from COVID-19, particularly among those experiencing long COVID or persistent post-acute symptoms. Numerous…
Review
Biased Agonism in Drug Discovery: Clinical Promise and Pitfalls
Vimala Ananthy, Priyadharsini Raman Palanisamy, Umamaheswari Subramanian
pp. 532–536 · DOI: 10.5530/jyp.20250058 · Published
The discovery of biased agonism as a pharmacological technique that enables specific receptor pathway activation through ligands transformed receptor pharmacology. The analysis evaluates the fundamental mechanisms and me…

Original Artcile

Article
Sustainable Management of Pencil Waste through Conversion to Rat Bedding
Fazlina Mustaffa, Geethaa Sahgal, Varatharajan Rajavel, Yamunna Parasmawaran, Mohamed Asem Ameerdin, Jeevandran Sundarasekar, Baala Sharmma, Vimalah Devi
pp. 537–542 · DOI: 10.5530/jyp.20250105 · Published
Background:On average, 20 tree barks are used for the production of animal bedding for Malaysian research universities that carry out animal testing yearly. Even though this figure looks small, sustainable environmental …
Article
In vitro Hepatoprotective Effect of Drymaria cordata Against Lipopolysaccharide-Induced Hepatotoxicity in HepG2 Cell Line
Josef Yakin, Faruk Alam
pp. 543–550 · DOI: 10.5530/jyp.20250071 · Published
Background:Medicinal plants have historically played a crucial role in healthcare, serving as the basis for many modern drugs. Among these, Drymaria cordata(L.) Willd. ex Schult., a small herbaceous plant of the Caryophy…
Article
Exploring the Antioxidant Properties and Bioactive Compounds of Methanolic Extract of Diplocyclos palmatus Seeds
Richa Yadav, Jaya Parkash Yadav
pp. 551–558 · DOI: 10.5530/jyp.20251475 · Published
Background:Concerns regarding the detrimental consequences of oxidative stress on human health have grown recently on a global scale and herbal treatment approaches to treat oxidative stress-related illnesses in humans a…
Article
A Comprehensive Study on Ludwigia palustris (L.) Elliott: Physicochemical Characterization, Phytochemical Screening, and Evaluation of Antioxidant and Antibacterial Activities
Vaibhav Kumar Rathi, Mukesh Singh Sikarwar, Pushpendra Kumar Shukla
pp. 559–570 · DOI: 10.5530/jyp.20250180 · Published
Objectives:This study explores microscopic features, physicochemical properties, preliminary phytochemical profile, antioxidant and antibacterial activity of Ludwigia palustris. Materials and Methods:Macroscopic and micr…
Article
Biological Profiling and Phytochemical Analysis of Peristrophe bicalyculata: Evaluating its Therapeutic Potential and Active Compounds
Raman Lakshmisundaram, Kalaivani Madhavaram Kuppusamy, Logeshwari Muruganandham, Krishna Priya Rajaram Baskaran, Dhanalakshmi Muniyandi, Mudiganti Ram Krishna Rao, Jayasutha Jayram
pp. 571–580 · DOI: 10.5530/jyp.20250031 · Published
Background:The present study deals the biological property of a medicinal plant, Peristrophe bicalyculata. This is a common herb used for a number of ailments ethno-pharmacologically. In the present study, the antioxidan…
Article
Postulation of Therapeutic Potential of Meha Mudgara Rasa in Management of Diabetic Neuropathy through High-Performance Thin Layer Chromatography (HPTLC) Analysis
Shailesh Deshpande, Meha Gandhi, Vaishali Deshpande
pp. 581–591 · DOI: 10.5530/jyp.20250163 · Published
Background:Meha Mudgara Rasa(MMR) is a classical Ayurvedic herbo-mineral formulation that is traditionally used in the management of diabetes. Despite its long-standing therapeutic use, scientific validation of its pharm…
Article
Solid-State Characterization of Fluconazole Polymorphs: Temperature and Time-Triggered Analysis
Afrasim Moin, VRSS Prashanth Pedamallu, Sateesha Shivally Boregowda, Rajamma Abbur Jayaramu, Sathvik Kudkuli, Amr Selim Abu Lila
pp. 592–603 · DOI: 10.5530/jyp.20251479 · Published
Background:An antifungal drug, fluconazole, was selected as a model drug in this study to comprehend the effect of temperature and moisture on polymorphic transformation. Materials and Methods:Three polymorphs of flucona…
Article
Development and Characterization of Ketoconazole-Loaded Nail Lacquer for the Topical Treatment of Onychomycosis
Pritam Timothy Pradhan, Aradhana Panigrahi, Jasaswi Ray, Rabi Sankar Dash, Gurudutta Pattnaik, Abhisek Sahu, Bikash Ranjan Jena, Yashwant Giri
pp. 604–611 · DOI: 10.5530/jyp.20251665 · Published
Background:Onychomycosisis is a fungal nail infection mainly caused by funguses like Trichophyton rubrum, Aspergillus, and various species of Candida that impact the nail. Symptoms can manifest as a color change of the n…
Article
Design and Evaluation of Activated Charcoal-Enriched Antibacterial Soap Using a Design of Experiments (DoE) Approach
Koushik Yetukuri, Surya Pavan Kumar Gollapudi, Aditya Reddy Mukkala, Guna Shankar Mandala, Ameenul Ahad Shaik, Ayush Katyayan, Rama Rao Nadendla
pp. 612–619 · DOI: 10.5530/jyp.20250006 · Published
Background:The formulation and optimization of an activated charcoal-based antibacterial soap were investigated to enhance cleansing efficacy and antimicrobial properties. The study was conducted at Chalapathi Institute …
Article
Formulation Design of Sel-Micro-Emulsifying Lipid Systems
Naser M.Y. Hasan
pp. 620–626 · DOI: 10.5530/jyp.20250153 · Published
Background:The increasing interest in the field of Lipid Self-Emulsifying Technology (LSET) is due to the fact that 40% of new chemical entities exhibit poor oral bioavailability because of their low water solubility. Se…
Article
Harnessing Beet Root Pigments as Natural Colorant for a Glossy Herbal Lipstick: Formulation and Evaluation
Ajit Nahak, Aditya Narayana Padhi, Anjan Kumar Mahapatra, Asish Sahu, Kakinada Sonu Kumar, Amaresh Prusty
pp. 627–635 · DOI: 10.5530/jyp.20250088 · Published
Background:Lipstick is a solid cosmetic designed to impart vibrant colour, hydration, and textural enhancement to the lips. With a growing consumer shift toward natural products. Interest in plant-based colorants and nat…
Article
Quality by Design-Driven Formulation and Evaluation of an Itraconazole Film-Forming Gel for Enhanced Antifungal Activity
Sachin Balkrishna Somwanshi, Harsha Kailas Donde
pp. 636–645 · DOI: 10.5530/jyp.20250014 · Published
Background:Itraconazole, a broad-spectrum antifungal agent, exhibits poor aqueous solubility and limited skin permeability, restricting its effectiveness in conventional topical formulations. Film-Forming Gels (FFGs) rep…
Article
Unveiling a New Ultra Violet-Spectrophotometric Strategy for Simultaneous Quantification of Adapalene and Erythromycin in Powders and Nanocarriers
Nisha Shirkoli, Vinayak Mastiholimath
pp. 646–652 · DOI: 10.5530/jyp.20250213 · Published
Background:This study is aimed to establish a novel and reliable UV-visible spectrophotometric method for simultaneous quantification of Adapalene and Erythromycin. Purpose:There is no documented Ultra Violet analysis fo…
Article
Evaluation of Anti-Gout Effect of Polyherbal Formulation Acupen in Monosodium Urate Crystal-Induced Gouty Arthritis via Anti-Inflammatory Action in Experimental Animal Model
Atul Desai, Hemshree Desai, Rutvij Desai, Anali Patel, Chirag Desai, Ankit Merai, Arindam Paul
pp. 653–660 · DOI: 10.5530/jyp.20251785 · Published
Aim:This study aimed to evaluate the anti-gout activity of ACUPEN formulation using the Monosodium Urate (MSU)-induced gouty arthritis model and assess its Xanthine Oxidase (XO) inhibitory activity. Materials and Methods…
Article
Anti-spermatogenic Activity of Polyherbal Formulation on Male Wistar Albino Rats
Parul Vasava, Guno Sindhu Chakraborthy
pp. 661–668 · DOI: 10.5530/jyp.20251709 · Published
Background:The development of plant-based alternatives is gaining thrust in contemporary research, with the traditional use as male contraceptive agents. To explore anti-spermatogenic properties of Polyherbal Formulation…
Article
Challenges and Strategies for Implementing Antimicrobial Stewardship Programs in India: Insights from Multiple Stakeholders
Yogendra Shrestha, Sunita Kularia, Prakashkumar Doddasamiah, Thiruvarangan Devarasan, Varadhan Thennarasi, Vinod H Jadhav
pp. 669–678 · DOI: 10.5530/jyp.20250133 · Published
Background:Hospitals routinely practise Antimicrobial Stewardship (AMS) to prevent antibiotic resistance and ensure medication safety. However, rising antibiotic resistance casts concern on AMS's usefulness. This study e…
Article
Therapeutic Effects of Benson’s Relaxation on Maternal Stress and Physiological Indicators in Antenatal Mothers with Pregnancy Induced Hypertension
Vruti Patel, Anita Praksasam, Shital Patel, Pinal Darji, Suresh Velumani, Khushi Jiendrabhai Patel, Khushi Mukeshbhai Patel
pp. 679–684 · DOI: 10.5530/jyp.20250164 · Published
Background:Hypertension during pregnancy, particularly Pregnancy-Induced Hypertension (PIH), presents a major challenge in maternal healthcare. It increases the risk of complications such as preeclampsia, eclampsia, and …
Article
A Study on Chemotherapy Induced Toxicities among Hospitalized Patients in Oncology Ward
Mohammed Ziauddin, Divya Amaravadi, Mohammed Ashfaq Hussain
pp. 685–690 · DOI: 10.5530/jyp.20250062 · Published
Background:Chemotherapy is an effective cancer treatment but chemotherapy-induced toxicity remains a major concern, as it can significantly affect patients' quality of life, lead to treatment intolerance and in some case…
Article
A Cross-Sectional Observational Study to Assess Red Cell Distribution Width as a Novel Biomarker for the Prediction of Severity of Acute Ischemic Stroke
Evangeline Gladwin, Mudra Patel, Riddhi Shah, Dharamraj Mistry, Arun Mishra, Ankit Shah, Mital Patel
pp. 691–696 · DOI: 10.5530/jyp.20250114 · Published
Background:Stroke, a leading cause of death and disability, is primarily classified into ischemic and hemorrhagic types. Red Cell Distribution Width, measures the variability in red blood cell size, is an emerging biomar…
Article
Digital Platform as a Source for Self-Medication: The Influence of Educational Factors
Lakshme Shree Vijayan, Yeoh Yong Khang, Sharranesh Raja, Shakthidaran Nair, Sabrina George, Usha Kumari, Win Mar Aye, Theingi Maung Maung
pp. 697–702 · DOI: 10.5530/jyp.20250193 · Published
Background:The growing use of digital platforms has transformed health information access and contributed to the global trend of self-medication. When making healthcare decisions, people in Malaysia, where internet usage…
Article
Impact of Pharmacist-Led Medication Optimization on Treatment Adherence and Quality of Life in Elderly Cancer Patients
Satish Karoli, M S Ganachari
pp. 703–709 · DOI: 10.5530/jyp.20251730 · Published
Background:Elderly cancer patients often face challenges related to polypharmacy, Medication-Related Problems (MRPs), and comorbidities, which can compromise treatment adherence and Quality of Life (QoL). Pharmacist-led …
Article
Depression, Anxiety, Stress and Loneliness among the Elderly Living in Families in Rural Karnataka, Southern India: A Cross-Sectional Study
Muneera Muneera, Mohammed Guthigar
pp. 710–716 · DOI: 10.5530/jyp.20250020 · Published
Background:Population aging is a global phenomenon with an increasing number of elderly individuals experiencing psychological problems. This study aimed to assess the prevalence of depression, anxiety, and stress among …
Article
Association Between Walking Intensity and Self-Reported Chronic Diseases among Adults in Abha: A Cross-Sectional Analysis
Abdullah Hassan Alasmri, Hassan M. AlShaiban, Othman Omair, Mohammed Mufateh Alaidan, Najim Z. Alshahrani
pp. 717–723 · DOI: 10.5530/jyp.20250021 · Published
Background:Chronic diseases are escalating globally, largely due to sedentary lifestyles accentuated in urban settings. This study aims to explore the relationship between walking intensity and self-reported chronic dise…
Article
Enhancing Medication Adherence and Symptom Management in Benign Prostate Hyperplasia Patients: A Hospital-Based Intervention Study
Lavanya Yaidikar, K. Hemasruthi, M. Jasmitha, N. Jyothipriya, K. Karunakaran, N. Anil Kumar
pp. 724–731 · DOI: 10.5530/jyp.20251532 · Published
Objectives:Benign Prostate Hyperplasia (BPH) is a common condition affecting aging males, characterized by prostate enlargement and associated urinary symptoms. Despite available treatments, medication adherence remains …
Article
Impact of Educational Intervention on Awareness of Polycystic Ovary Syndrome among Female Students: A Quasi Experimental Study
Azfar Athar Ishaqui, Sara Naqvi, Hania Kauser, Javeria Farooq, Dua Bufail, Narendar Kumar, Khalid Mubarak Orayj, Muhammad Imran
pp. 732–739 · DOI: 10.5530/jyp.20250025 · Published
Background:Polycystic Ovary Syndrome (PCOS) is one of the most common problems among women during their childbearing age. Polycystic ovary syndrome prevalence and complications are snowballing due to failure of early dia…
Article
Generation-Z and Sleep: Evaluating Quality, Practices, and Impacts among Students in Andhra Pradesh, India
Pavan Kumar Yanamadala, Nandini Palivela, Lohitha Gumma, Lakshmi Prasanna Yarrabothula, Bhargavi Gumma, Sanuhya Kollati, Abhi Chowdary Gannamaneni, Sri Kumari Konkimalla
pp. 740–746 · DOI: 10.5530/jyp.20250053 · Published
Background:Generation Z students frequently encounter difficulties such as academic demands, prolonged exposure to screens, and psychological stressors, all of which adversely affect their sleep quality. This study inves…

Case Report

Article
Cervical Myelomeningocele: A Rare Neural Tube Defect: A Case Report
Megha Patel, Dilsar Gohil
pp. 747–751 · DOI: 10.5530/jyp.20250101 · Published
This case presents a 3-month-old infant with a progressively enlarging Cervical swelling (C2-C3). Magnetic Resonance Imaging revealed a 17×4 mm cystic lesion, consistent with a diagnosis of Cervical Myelomeningocele (cMM…