Exploring the Antioxidant Properties and Bioactive Compounds of Methanolic Extract of Diplocyclos palmatus Seeds
Richa Yadav1, Jaya Parkash Yadav1,2★★ Corresponding author
- 1Department of Genetics, Maharshi Dayanand University, Rohtak, Haryana, INDIA.
- 2Indira Gandhi University, Meerpur, Rewari, Haryana, INDIA.
CORRESPONDENCE
Jaya Parkash Yadav
Department of Genetics, Maharshi Dayanand University, Rohtak, Haryana, INDIA.
Received: 02-04-2025; Revised: 27-05-2025; Accepted: 15-07-2025.
Volume 17, Issue 3 · pp. 551–558 · PUBLISHED · DOI: 10.5530/jyp.20251475
ABSTRACT
Background:Concerns regarding the detrimental consequences of oxidative stress on human health have grown recently on a global scale and herbal treatment approaches to treat oxidative stress-related illnesses in humans are now a hot topic in traditional medicine. Diplocyclos palmatusis one such herbal remedy, it is utilised to treat a wide range of illnesses because of its antioxidant qualities. To provide scientific evidence for this claim the study was planned to evaluate the antioxidant capabilities of D. palmatusSeed Methanolic Extract (SME) using both in vitroand in vivoinvestigations. Materials and Methods:SME prepared with cold percolation method was first evaluated for phytochemical constituents. In vitroassays were carried out to get a preliminary indication of the antioxidant capacity of extract in a regulated environment whereas, in vivoanalysis was done using an induced Wistar rat model to justify its biological relevance. The main bioactive components in SME were identified using the RP-HPLC technique. Results:SME has proven to be an effective antioxidant in both in vitroand in vivoexperiments. The RP-HPLC analysis has revealed the presence of quercetin and vanillic acid as the main antioxidants in SME. All the results were obtained as Mean±Standard Deviation. Tests including Student’s T-test (unpaired) and ANOVA were applied to compare the Statistical difference. A ‘p’ value of less than 0.05 was considered significant. Conclusion:The research findings indicate that D. palmatusSME demonstrates noteworthy antioxidant properties. Thus, the findings could contribute to developing a safe and effective natural health supplement.
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Yadav, R., & Yadav, J. P. (). Exploring the Antioxidant Properties and Bioactive Compounds of Methanolic Extract of Diplocyclos palmatus Seeds. Journal of Young Pharmacists, 17(3), 551–558. https://doi.org/10.5530/jyp.20251475