jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Journal of Young PharmacistsNOW IN
Article

A Cross-Sectional Study to Assess the Effectiveness of Ethereum and Nexus Blockchain Platforms in Preventing Counterfeit Drugs

Sriram Shanmugam1, Poonguzhali Viswanathan2, Sahana Fathima Amudha2, Dhivya Ramachandran2, Thamarai Selvan Mohan3, Shakthivel Chinnasamy Dhandapani5★, Gokulavasa Nagarajan5, Narayanasamy Krishnasamy5, Kalpana Ramachandran66★ Corresponding author

  1. 1Department of Pharmacy Practice, Sri Ramakrishna Institute of Paramedical Sciences, College of Pharmacy, Coimbatore, Tamil Nadu, INDIA.
  2. 2Department of Physics, Sri Ramakrishna College of Arts and Science, Coimbatore, Tamil Nadu, INDIA.
  3. 3Department of Electronics, Sri Ramakrishna College of Arts and Science, Coimbatore, Tamil Nadu, INDIA.
  4. 4Vice-Chancellor, The Tamil Nadu Dr. M.G.R. Medical University, Chennai, Tamil Nadu, INDIA.
  5. 5Vice-Chancellor, The Tamil Nadu Dr. M.G.R. Medical University, Chennai, Tamil Nadu, INDIA.
  6. 6Department of Epidemiology, The Tamil Nadu Dr. M.G.R. Medical University, Chennai, Tamil Nadu, INDIA.

CORRESPONDENCE

Shakthivel Chinnasamy Dhandapani

Vice-Chancellor, The Tamil Nadu Dr. M.G.R. Medical University, Chennai, Tamil Nadu, INDIA.

shakthineuropharm87@gmail.com

Received: 23-05-2025; Revised: 03-07-2025; Accepted: 18-09-2025.

Volume 17, Issue 4 · pp. 991–996 · PUBLISHED · DOI: 10.5530/jyp.20250115

View on JYP original site ↗

ABSTRACT

The rise of counterfeit medicines poses serious health risks to the public and threatens the credibility of pharmaceutical companies. Blockchain technology is gaining attention for its potential to enhance the security and transparency of the pharmaceutical supply chain. This study compares the performance of two blockchain platforms, Ethereum and Nexus, in detecting and preventing counterfeit drugs. A virtual observation system was used to examine how Ethereum and Nexus addressed major challenges in counterfeit drug prevention. Two specialists with expertise in both blockchain technology and healthcare evaluated the platforms using two assessment tools: The Global Quality Scale (GQS) to measure overall effectiveness and the modified DISCERN scale to assess credibility of the information. Nexus outperformed Ethereum in both effectiveness and credibility. Evaluator 1 reported median GQS scores of 4.5 for Nexus and 3.8 for Ethereum, while Evaluator 2 reported scores of 4.2 and 3.8, respectively. These findings indicate that Nexus demonstrated higher efficiency in detecting fake drugs and ensuring supply chain integrity. Blockchain technology shows promise in strengthening pharmaceutical supply chain security. Between the two platforms studied, Nexus was found to be more effective than Ethereum in preventing counterfeit drugs. These results provide valuable insights for pharmaceutical stakeholders and policymakers seeking to implement blockchain-based solutions for drug tracking and security.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Shanmugam, S., Viswanathan, P., Amudha, S. F., Ramachandran, D., Mohan, T. S., Dhandapani, S. C., Nagarajan, G., Krishnasamy, N., & Ramachandran6, K. (). A Cross-Sectional Study to Assess the Effectiveness of Ethereum and Nexus Blockchain Platforms in Preventing Counterfeit Drugs. Journal of Young Pharmacists, 17(4), 991–996. https://doi.org/10.5530/jyp.20250115