Volume 4, Issue 3

Parasuraman S

pp. 127–128 · DOI: 10.4103/0975-1483.100014

Dear Professional Colleagues, Researchers, Fellow Students and Readers, First, I on behalf of the Editorial Board would like to thank all authors, reviewers, readers, subscribers, editorial staff and publisher for their …

Priyanka K, Abdul Hasan Sathali A

pp. 129–137 · DOI: 10.4103/0975-1483.100016

Solid lipid nanoparticles (SLNs) are an alternative carrier system used to load the drug for targeting, to improve the bioavailability by increasing its solubility, and protecting the drug from presystemic metabolism. Th…

Sahoo S, Chakraborti CK, Behera PK, Mishra SC

pp. 138–145 · DOI: 10.4103/0975-1483.10017

Till now very few formulations are available from which the drug is uniformly absorbed, so that the safe and effective blood level of norfloxacin could be maintained for a prolonged period. To fulfill this requirement, a…

Gurinder Singh, Roopa S. Pai, V. Kusum Desi

pp. 146–156 · DOI: 10.4103/0975-1483.10020

Furosemide is a class IV biopharmaceutical classification system drug having poor water solubility and low bioavailability due to the hepatic first-pass metabolism and has a short half-life of 2 h. To overcome the above …

Pabari RM, Ramtoola Z

pp. 157–163 · DOI: 10.4103/0975-1483.10021

The aim of this study was to evaluate the influence of disintegration mechanism of various types of disintegrants on the absorption ratio (AR), wetting time (WT), and disintegration time (DT) of orodispersible tablets (O…

Patel RK, Patel MA, Saralai MG, Gandhi TR

pp. 164–170 · DOI: 10.4103/0975-1483.10022

This study was designed to evaluate the effects of Solanum xanthocarpum fruit extract in ethylene-glycol-induced urolithiasis in the male Wistar rats. Nephrolithiasis was induced in male Wistar rats by adding ethylene gl…

Patel SB, Santani D, Shah MB, Patel VS

pp. 171–176 · DOI: 10.4103/0975-1483.10024

Bryonia laciniosa Linn. (Cucurbitaceae) seed is used in traditional medicine for a number of ailments including metabolic disorders. This investigation was carried out to investigate the anti-hyperglycemic and anti-hyper…

Ambhore NS, Antony S, Mali JK, Kanhed AM, Bhalerao AR, Bhojraj S

pp. 177–183 · DOI: 10.4103/0975-1483.10026

Parkinson's Disease (PD) is a neurodegenerative disorder in the nigrostriatal pathway of animals and humans and is responsible for most of the movement disorders, including rigidity. The present study aimed to determine …

Faizul Azam, Arwa M. Madi, Hamed I. Ali

pp. 184–192 · DOI: 10.4103/0975-1483.10027

Monoamine oxidase B (MAO-B) inhibitory potential of adenosine A2 receptor (AAR) antagonists has raised the possibility of designing dual-target-directed drugs that may provide enhanced symptomatic relief and that may als…

Hassali MA, Shafie AA, Khan TM

pp. 193–198 · DOI: 10.4103/0975-1483.10028

The current study aimed to explore the public views and expectation about a successful communication process between the healthcare providers/physicians and patients in Penang Island, Malaysia. A cross-sectional study wa…