Journal of Young Pharmacists
Volume 10, Issue 3
· pp. 249–379 · 30 articles
- Volume
- 10
- Issue
- 3
- Published
- Pages
- 249–379
- Articles
- 30
- Sections
- 6
- ISSN
- Print - 0975-1483 | Online - 0975-1505
- Journal
- JYP
In this issue
Message from Editor’s Desk
- Article
Journal of Young Pharmacists - Fact sheet
Subramani Parasuraman
pp. 249 · DOI: 10.5530/jyp.2018.10.56 · Published
I would like to thank all the authors, researchers, scientist, readers, editorial board members and publisher for constant support for past nine years. With your support, currently Journal of Young Pharmacists (JYP) publ…
Editorial
- Forum Article
Diabetes Related Distress and Depression: An Emerging Threat to Human Health
Chidambaram Ramasamy
pp. 250–251 · DOI: 10.5530/jyp.2018.10.57 · Published
Diabetes is a disease which is intricate to manage. According to the International Diabetes Federation (IDF), more than 415 million people have diabetes in the world, and it is predicted that the number will rise to 642 …
Original Article
- Article
Molecular Docking, 3D Structure-Based Pharmacophore Modeling, and ADME Prediction of Alpha Mangostin and its Derivatives against Estrogen Receptor Alpha
Muchtaridi Muchtaridi, Doni Dermawan, Muhammad Yusuf
pp. 252–259 · DOI: 10.5530/jyp.2018.10.58 · Published
Objective:The aims of this study are to identify the molecular interactions and the pharmacophore-fit of of α mangostin and its derivatives with estrogen receptor α (ERα) using computational simulation approaches to obta…
- Article
Immunoinformatics Based Vaccine Design for Zea M 1 Pollen Allergen
Anamika Basu, Anasua Sarkar, Piyali Basak
pp. 260–266 · DOI: 10.5530/jyp.2018.10.59 · Published
Objective: Zea m1 is one of the most common aeroallergens, causing allergy. This pollen allergen, present in maize, is responsible for type I hypersensitivity reaction. Despite having available X ray crystal structure of…
- Article
Synthesis, Characterization and Biological Evaluation of Novel 1, 4-Benzodiazepine Derivatives as Potent Anti-Tubercular Agents
M. Murali Krishna Kumar, T. Mohan, G. Krupa Mai, G.P.V Sangeeta, K. Purna Nagasree
pp. 267–271 · DOI: 10.5530/jyp.2018.10.60 · Published
Background:Benzodiazepines are interesting compounds due to their therapeutic properties. TB chemotherapy is highly regulated and Its research research is often considered non-remunerative. Hence, there remains a pressin…
- Article
Optimization of Imidazolium-Based Ionic Liquid-Microwave Assisted Extraction for Oxyresveratrol Extraction from Morus alba Roots
Tanfidz Alishlah, Abdul Mun’im, Mahdi Jufri
pp. 272–275 · DOI: 10.5530/jyp.2018.10.61 · Published
Objective:The application of ionic liquids as solvent in the microwave assisted extraction (MAE) method has been developed for extraction of secondary metabolites from plants. However, oxyresveratrol extraction from Moru…
- Article
Nanoparticles for the Treatment of Lung Cancers
Raahulan Sivarajakumar, Dhamini Mallukaraj, Madhurya Kadavakollu, Niveditha Neelakandan, Sandhya Chandran, Saravanan Bhojaraj, Veera Venkata Satyanarayana Reddy Karri
pp. 276–281 · DOI: 10.5530/jyp.2018.10.62 · Published
On the row of various cancers in the world, the Lung cancer falls to number two in both female and male. Various surgical and non-surgical therapeutic approaches including chemotherapy, photodynamic therapy, and radiothe…
- Article
Evaluation of the Behaviour of Violet Acid Pigment 43 in Formulations of Shampoos and Conditioners in Bleached Hair
Mariel Jordana Lopes Pereira, Edilson Martins Rodrigues Neto, Francisco Josimar Girão Júnior, Maria Luisa Bezerra de Macedo Arraes, Tamara Gonçalves Araujo
pp. 282–287 · DOI: 10.5530/jyp.2018.10.63 · Published
Objective:The objective of this work was to evaluate the behavior of Acid Violet 43 pigment shampoos and conditioners formulations and when applied to hair through 10 formulations. Method:10 formulations were developed, …
- Article
Protective Effects of Anthocyanin Fraction of Berberis integerrima Bunge Fruits against H2O2 Induced Cytotoxicity in MCF7 and HepG2 Cells
Fatemeh Farmani, Zahra Sabahi
pp. 288–291 · DOI: 10.5530/jyp.2018.10.64 · Published
Objective:Berberis integerrima Bunge show different pharmacological effects. Its fruits are rich sources of anthocyanin with biological activities. The aim of this study was evaluation of protective effects of isolated a…
- Article
Amelioration of 1, 2 Dimethylhydrazine Induced Tumor Promotion Response by Novel Benzimidazole Derivative Nanoparticle in Wistar Rats
S.S. Rajendran, G. Geetha, R. Venkatanarayanan, N. Santhi
pp. 292–298 · DOI: 10.5530/jyp.2018.10.65 · Published
Background:Colon cancer is one of the most common malignancies in many regions of the world and is thought to arise from the accumulation of mutations in a single epithelial cell of the colon and rectum. The benzimidazol…
- Article
Anti-Inflammatory Activity of Combined Aerodisperse System in the Conditions of Experimental Cervical Lymphadenite
Khadzieva Zahra Dzamaleevna, Aleynikova Nelly Segeevna, Pozdnyakov Dmitry Igorevich, Rybalko Anastasiya Evgenievna
pp. 299–302 · DOI: 10.5530/jyp.2018.10.66 · Published
Objective:The aim of this study was to assess the presence of an antiinflammatory activity of a new combined aerodisperse system under conditions experimental lymphadenite.Materials and Methods: Lymphadenite was reproduc…
- Article
Protective Activity of Chitosan Nanoparticle against Cadmium Chloride Induced Gastric Toxicity in Rat
Giftania Wardani, Koerniasari Eraiko, Koerniasari K, Sri Agus Sudjarwo
pp. 303–307 · DOI: 10.5530/jyp.2018.10.67 · Published
Objective:This study was carried to investigate the role of chitosan nanoparticle in protecting against cadmium chloride-induced gastric toxicity in the rat. Methods:The 50 male rats were divided into 5 group: negative c…
- Article
Comparative Analysis of Two Methodologies for Determination of HDL Cholesterol
Rosana Deyse Ponte Portela, Edilson Martins Rodrigues Neto, Francisco Josimar Girão Júnior, Jamile Magalhães Ferreira, Renata de Sousa Alves, Teresa Maria de Jesus Ponte Carvalho, Benvindo Aécio Pinheiro Holanda
pp. 308–312 · DOI: 10.5530/jyp.2018.10.68 · Published
Objective: The present work is an analytical and prospective study on the determination of HDL-cholesterol through two different methodologies, precipitation and direct method, in a group of 51 patients attended by a sch…
- Article
Perceptions of Prescribers towards Electronic Prescription: A Pre-Implementation Evaluation
Dhanya S Palappallil, Carol Pinheiro
pp. 313–317 · DOI: 10.5530/jyp.2018.10.69 · Published
Objective: Electronic (e) prescribing is computerised prescribing. The Government of Kerala has started the e-health initiative. The objective of this study was to obtain the perceptions of prescribing doctors on e-presc…
- Article
Comparison of Drug Related Problems Associated with Use of Narrow Therapeutic Index Drugs and Other Drugs in Hospitalized Patients
Kapil Iyer, Neha Dilipkumar, Sharmin Vasaya, Sunita Pawar, Arundhati Diwan
pp. 318–321 · DOI: 10.5530/jyp.2018.10.70 · Published
Objectives:To identify and categorize types of Drug Related Problems (DRPs), assess various risk factors for developing DRPs and delineate if drugs with narrow therapeutic index or non-narrow therapeutic index drugs caus…
- Article
Cost of Illness Analysis of Knee Osteoarthritis in a Tertiary Care Hospital
Saida Firdose Venkatagiri Shaik, Dhivya Kothandan, Pravallika Singareddy, Santhosh Sanku
pp. 322–325 · DOI: 10.5530/jyp.2018.10.71 · Published
Background:Osteoarthritis (OA) is the most common rheumatologic problem affecting people all over the world. The economic impact of OA is significant due to the effect of disability, co morbid disease and the expense of …
- Article
Retrospective Qualitative and Quantitative Analysis of Adverse Events following Vaccination
Hardik Patel, Samidh Shah, Mira Desai, V Kalaiselvan, G.N Singh
pp. 326–329 · DOI: 10.5530/jyp.2018.10.72 · Published
Background: Vaccination is an essential component of the public health programs. A small minority of persons may experience mild, time limited adverse reactions, however, in rare cases, it may be serious. Hence there is …
- Article
Assess the Clinical Efficacy of Streptokinase in Thrombolysed Patients of Acute ST Segment Elevation Myocardial Infarction
N. Swetha Ramya, J. Bhargava Narendra, Veera Raghavulu B, M. Satti Babu, N. Dharma Teja, K. P. Hema Malini, S.S. Prathap, N. Swetha Ramya, J. Bhargava Narendra, Veera Raghavulu B, M. Satti Babu, N. Dharma Teja, K. P. Hema Malini, S.S. Prathap
pp. 330–333 · DOI: 10.5530/jyp.2018.10.73 · Published
Introduction: Acute myocardial infarction is the most important and feared consequence of coronary artery disease. STEMI is the one of that kind and it occurs by formation of a vulnerable plaque from atherosclerosis and …
- Article
Effectiveness of Second-Line Agents in the Treatment of Uncomplicated Type 2 Diabetes Mellitus: An Observational Tertiary-Care Based Study
Rupam Gill, Shalini Adiga, Muralidhar Varma
pp. 334–339 · DOI: 10.5530/jyp.2018.10.74 · Published
Background:The rational prescribing of second-line drugs in type 2 diabetes mellitus (DM) require clear guidelines. There is no sufficient empirical evidence to support the use of one second-line agent over the other and…
- Article
Chemotherapy-Induced Adverse Drug Reactions in Pediatric Oncology
Falguni Parande, Aanchal Anand, Mayuri Khaparde, Sunita Pawar
pp. 340–343 · DOI: 10.5530/jyp.2018.10.75 · Published
Background: Chemotherapy accounts to high vulnerability toward Adverse Events (AEs) as it involves highly complicated regimens. Objective of the study is to identify, assess, grade and categorize chemotherapy-induced adv…
- Article
Clinical Trial of Nanoencapsulated Centella asiatica and Zingiber officinale to Improve Cellulite and Subcutaneous Adipolysis
Ani Kristiyani, Zullies Ikawati, Yenny Meliana, Reza Yuridian Purwoko
pp. 344–379 · DOI: 10.5530/jyp.2018.10.76 · Published
Objective:The purpose of this study was to determine the effect of nanoencapsulated Centella asiatica and Zingiber officinale extract, with the dose of 3000 mg/day, in reducing cellulite and improving the composition of …
- Article
Management of Warfarin Therapy: A New Point-Of-Care Monitoring Service by Community Pharmacists in India
Deepalakshmi M, Christy Joseph, Carolyne Jacob, Arun K P, Ponnusankar S
pp. 350–353 · DOI: 10.5530/jyp.2018.10.77 · Published
Objective:To introduce the implementation of point of care INR monitoring service by community pharmacists for optimizing the therapy outcomes of Warfarin, used widely for its anticoagulant activity both as a treatment a…
- Article
Hepatocurative Effect of Saussurea lappa C.B Clarke and Artemisia absinthium, Linn in Chronic Hepatitis B
Shabnam Ansari, Mohammad Akhtar Siddiqui, Mohammad Maaz
pp. 354–357 · DOI: 10.5530/jyp.2018.10.78 · Published
Objective:Repeated immune attacks in chronic hepatitis B produce recurrent inflammation in the liver and render it to develop fibrous tissue and carcinoma. Hence, present study aims to evaluate the hepatocurative effect …
Short Communication
- Communication
Prevalence of Antimicrobial Resistant Pathogens in Severe Sepsis and Septic Shock Patients
Merin Babu, Vidya P Menon, Uma Devi P
pp. 358–361 · DOI: 10.5530/jyp.2018.10.79 · Published
Emergence of antimicrobial resistance is turning to be a life threatening problem in the treatment of patients with severe sepsis and septic shock. Many organisms display a multidrug resistant (MDR) pattern, which limits…
Case Report
- Article
Cases of Adverse Drug Events in Pediatrics: Prospective Study at a Hospital in Rabat (Morocco)
Laila Torissi, A. Soulaymani, A. Mokhtari, Soulaymani Rachida
pp. 362–366 · DOI: 10.5530/jyp.2018.10.80 · Published
Pharmacovigilance aims to guarantee the safe use of medicines. It is based on the reporting of adverse effects by health professionals, industry and the public. Pharmacovigilance is the monitoring of drugs and the preven…
- Article
Causative Organisms of Cellulitis – A Retrospective Study
Vedha Pal Jeyamani S, Asha K Rajan, Indumathi S, Divya R, Lavanya R, Prema M, Narendra Babu
pp. 367–370 · DOI: 10.5530/jyp.2018.10.81 · Published
Background:Cellulitis, especially of the lower limbs is found to be more common now-a-days in both the sexes. Ascending cellulitis was found to pose both short and long term morbidities. Objective and Methodology:The fol…
- Article
Wilson Disease with Hepatic Impairment and Thrombocytopenia: A Case Report
Krishnan Karthickeyan, Chegireddy Mahindranath Reddy, Jahangeer Batcha Noor Mohamed, Kothagundu Vaibhavi
pp. 371–373 · DOI: 10.5530/jyp.2018.10.82 · Published
Introduction: Wilson disease is a rare autosomal recessive disorder. The Case report describes the penicillamine induced thrombocytopenia. Case Report:A 14-year-old girl presented with previously diagnosed with Wilson di…
- Article
Psychosis and Rodenticides: A Case Report
Tenzin Tsundue, Khayati Moudgil
pp. 374–376 · DOI: 10.5530/jyp.2018.10.83 · Published
Objective: A poison can be any substance that can be taken through any means with net production of toxicity, which may result into death and coma as well. The evolution of rodenticides through history, witnesses the lar…
- Article
Prosthodontic Management of a Patient with Parkinson’s Disease- A Case Report
K. Pavithra, Antonette Rhea, M. Dhanraj, Pravinya P
pp. 377–379 · DOI: 10.5530/jyp.2018.10.84 · Published
Introduction: Parkinson’s disease is a neurological disorder characterized by tremors, rigidity, bradykinesia and postural instability. Impairment of motor skills and cognition compromise the patient’s diet, nutrition an…
Corrigendum
- Article
Corrigendum: Enhanced Systemic Exposure and Efficacy of Diltiazem from Novel Microemulsion Formulation: Characterization, in vitro Release, in vivo Pharmacokinetic and Efficacy Evaluation
K. Pavithra
pp. 380 · DOI: · Published
The article titled “ Enhanced systemic exposure and efficacy of diltiazem from novel microemulsion formulation: characterization, in vitro release, in vivo pharmacokinetic and efficacy evaluation.” has been published in …