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Journal of Young Pharmacists volume 10, issue 2 cover
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Cover: Journal of Young Pharmacists

Journal of Young Pharmacists

Volume 10, Issue 2

· pp. 131–248 · 26 articles

Volume
10
Issue
2
Published
Pages
131–248
Articles
26
Sections
6
ISSN
Print - 0975-1483 | Online - 0975-1505
Journal
JYP
EditorialReview ArticleOriginal ArticleShort CommunicationLetter to editorCase Report

In this issue

Editorial

  1. Forum Article

    Green Chemistry – An Environmentally Benign Chemistry

    Ravichandran V

    pp. 131 · DOI: 10.5530/jyp.2018.10.30 · Published

    Chemistry is a distinguished part of our daily lives. Food and drink has been made safe to consume, the development of cosmetics allowed us to beautify and venerate our appearances and the whole area of pharma ceuticals …

Review Article

  1. Review

    Phase Diagrams for Three Component Mixtures in Pharmaceuticals and its Applications

    Abhishek Sunil Dhoot, Anup Naha, Juhi Priya, Neha Xalxo

    pp. 132–137 · DOI: 10.5530/jyp.2018.10.31 · Published

    A phase is a physically discrete and chemically homogeneous portion of a system, separated by boundaries from other portions of the system. The phase rule given by J.W Gibbs in 1874 is applied to define a system composed…

  2. Review

    Warning Signs and Symptoms of Oral Cancer and its Differential Diagnosis

    Kavitha Muthu, Vedam Vaishnavi, Ganapathy Sivadas

    pp. 138–143 · DOI: 10.5530/jyp.2018.10.32 · Published

    Oral Cancer (Oral Squamous Cell Carcinoma; OSCC) contributes to one of the important causes of mortality in human beings. These impending malignancies however may present clinically with warning signs and symptoms which …

  3. Review

    Chitinases as Antibacterial Proteins: A Systematic Review

    Suelen Carneiro de Medeiros, José Edvar Monteiro-Júnior, Gleilton Weyne Passos Sales, Thalles Barbosa Grangeiro, Nádia Accioly Pinto Nogueira

    pp. 144–148 · DOI: 10.5530/jyp.2018.10.33 · Published

    Chitinases are hydrolases that catalyze the cleavage of the β-1,4-Oglycosidic linkages in chitin, a polysaccharide abundantly found in nature. Chitin is an important structural component of the cell wall of most fungi an…

  4. Review

    Nebivolol: An Appealing, Awaited and Nitric Oxide Potentiator Drug for the Treatment of Heart Failure

    Aryendu Kumar Saini, Pranay Wal, Manisha Verma, Suresh Chandra, Anurag Singh, Sanjeev Yadav, Himanshu Bansode, Kumar Nischaya, Nikita Saraswat

    pp. 149–154 · DOI: 10.5530/jyp.2018.10.34 · Published

    Nebivolol is a third generation beta-blocker that possesses the highest selectivity for beta-1 receptors than beta-2 receptors than any other beta blocker in its class. Long-term therapy of nebivolol, in clinical trials,…

Original Article

  1. Article

    Nephroprotective Effect of Anethum graveolens in a Murine Model of Gentamicin induced Nephrotoxicity

    Pragati Srivastava, Rashmi Rao R, Preethi J Shenoy, Poornima Ajay Manjrekar, S Teerthanath, Bhuvaneshwari S

    pp. 155–158 · DOI: 10.5530/jyp.2018.10.35 · Published

    Background: Antioxidant rich herbs possess significant activity against various disease conditions induced by oxidative stress. Anethum graveolens is a rich source of bioactive compounds that possess varying pharmacologi…

  2. Article

    Phytochemical Analysis, Antioxidant Properties and Brine Shrimp Lethality of Unripe Fruits of Solanum viarum

    Welligton Luciano Braguini, Natalia Valendolf Pires, Bruno Bianchin Alves

    pp. 159 · DOI: 10.5530/jyp.2018.10.36 · Published

    Objective: The aim of the study was evaluate the tannin content, antioxidant activity and the lethality of unripe fruits extract of Solanum viarum Dunal (Solanaceae) against brine shrimps. Methods: The tested samples for…

  3. Article

    Evaluation of the Antifungal Effect Vitis vinifera Extract on Candida albicans

    Leandro Maciel Uchoa Gadelha, Lídia Audrey Rocha Valadas, Nicole de Mello Fiallos, Sônia Luque Peralta, Keniesd Sampaio Mendonça, Mara Assef Leitão Lotif, Gilvan Lima Bezerra, Márcio Glauber Lopes de Aguiar, Érika Sabóia Guerra Diógenes, Edilson Martins Rodrigues Neto, George Otávio Asevedo, Ana Cristina de Mello Fiallos

    pp. 164–168 · DOI: 10.5530/jyp.2018.10.37 · Published

    Objective: This research analyzed in vitro the antifungal activity of the solution composed by grapes seed extract Vitis vinifera (Doctor’s A-Z®) against Candida albicans (ATCC 20231) species aiming to determine the mini…

  4. Article

    Inhibition of HIV-1 Reverse Transcriptase of Selected Indonesia Medicinal Plants and Isolation of the Inhibitor from Erythrina variegata L. Leaves

    Alvi Kusuma Wardani, Abdul Mun’im, Arry Yanuar

    pp. 169–172 · DOI: 10.5530/jyp.2018.10.38 · Published

    Objective: This research was conducted to screen inhibition of HIV-1 reverse transcriptase activity of selected Indonesia medicinal plants and to isolate HIV-1 reverse transcriptase inhibitor from Erythrina variegata lea…

  5. Article

    Analysis of Novel C-X-C Chemokine Receptor Type 4 (CXCR4) Inhibitors from Hexane Extract of Euclea crispa (Thunb.) Leaves by Chemical Fingerprint Identification and Molecular Docking Analysis

    Chella Perumal Palanisamy, Anofi Omotayo Tom Ashafa

    pp. 173–177 · DOI: 10.5530/jyp.2018.10.39 · Published

    Objectives: To evaluate the potential inhibitors aginst CXCR4 from hexane extract of Euclea crispa (E. crispa) leaves. Methods: The natural compounds were identified and charecterized through GC-MS analysis. Molecular do…

  6. Article

    Molecular Modeling and Docking Assessment of Thymic Stromal Lymphopoietin for the Development of Natural Anti Allergic Drugs

    Rahma Muhammad Adamu, B. K. Malik

    pp. 178–182 · DOI: 10.5530/jyp.2018.10.40 · Published

    Objective: To model a 3D-structure of Thymic Stromal Lymphopoietin (TSLP) and docking of small molecules for development of novel natural anti-allergic drug. Method: Crystal structure of the Mus musculus cytokine recepto…

  7. Article

    FOXP3 Modulation of Quercetin-3-O-rhamnoside and its Impacts on Lupus Nephritis Mice

    Niken Indriyanti, Joewono Soeroso, Junaidi Khotib

    pp. 183–186 · DOI: 10.5530/jyp.2018.10.41 · Published

    Background: Quercetin-3-O-rhamnoside (QUE) has anti-inflammatory and anti-oxidative effects which probably beneficially used in lupus. Objective: This research was focused on analyzing the effects of QUE on FOXP3 modulat…

  8. Article

    Ethnomedicinal Plants Used for the Treatment of Malaria in Malaka, West Timor

    Maximus M Taek, Bambang Prajogo EW, Mangestuti Agil

    pp. 187–192 · DOI: 10.5530/jyp.2018.10.42 · Published

    Objective: This study aims to document ethnomedicinal plants used in the traditional treatment of malaria in some areas of Malaka District in West Timor, Indonesia. Methods: Semi-structured questionnaire interviews and f…

  9. Article

    Antioxydant and Endotheliotropic Properties 4-Hydroxy-3,5-Di-Tret-Butyl Cinnamic Acid under Conditions of Experimental Brain Ischemia

    Pozdnyakov DI, Voronkov AV, Zolotych DS, Arlt AV

    pp. 193–196 · DOI: 10.5530/jyp.2018.10.43 · Published

    Objective: To assess the effect of 4-hydroxy-3,5-di-tret-butyl cinnamic acid on the state of endothelial function under conditions of experimental cerebral ischemia. Materials and Methods: Antioxidant properties of 4-hyd…

  10. Article

    Effect of Nadi Shuddhi Pranayama, Kati Chakrasana and Vakrasana on Depression and Glycemic Control in Type 2 Diabetes Mellitus

    Raja D, Deepthi Merin Raju, Indu TH, Sruthy KV, Jayakumar C, Ponnusankar S

    pp. 197–201 · DOI: 10.5530/jyp.2018.10.44 · Published

    Introduction: Diabetes mellitus (DM) is a predominant source of morbidity in India. The incidence of depression is found to be increased among type 2 DM patients that makes the glycemic control as an exhaustive task and …

  11. Article

    Evaluation of Predisposing Factors Associated with Suspected Adverse Drug Reactions of Hospitalized Patients

    Manoj K Mudigubba, Yogananda Rajashekarachari, Saurabh Dahiya

    pp. 202–207 · DOI: 10.5530/jyp.2018.10.45 · Published

    Objectives: To study the incidence and to evaluate the risk factors of suspected adverse drug reactions developed in the hospitalized patients of various departments and to assess the causality and severity of adverse dr…

  12. Article

    Impact of Intensified Pharmaceutical Interventions in Medication Adherence in Chronic Kidney Disease Patients

    Dilip Chandrasekhar, VM Ganesan, Sreelekha Sreekumar, Anuja Pradeep, Asha Susan Geoji, Athira Elezabath George, Athira V

    pp. 208–212 · DOI: 10.5530/jyp.2018.10.46 · Published

    Aim: The study aims to evaluate the medication adherence behavior of individuals by using validated questionnaire and to enhance the adherence by using various cost effective interventional methods which likely have a gr…

  13. Article

    Pattern of Adverse Drug Reactions Reported with Use of Antimicrobial Drugs in a Tertiary Care Hospital

    Shraddha Milind Pore, Shreyas Ramchandra Burute, Amar Dinkar Shinde, Sunita Jaiprakash Ramanand

    pp. 213–217 · DOI: 10.5530/jyp.2018.10.47 · Published

    Objective: The present study was undertaken to evaluate pattern, commonly implicated drugs, causality and severity of adverse drug reactions (ADRs) reported with antimicrobial drugs. Methodology: Antimicrobial drug relat…

  14. Article

    Incidence of Early Related–Complications of Port-A Catheter and Impact of Clinical Pharmacist Participation and Counselling Outcomes

    Anmar Al-Taie, Aygül Koseoğlu

    pp. 218–221 · DOI: 10.5530/jyp.2018.10.48 · Published

    Background: Port-A catheter is an implanted device used for frequent chemotherapy administration. It is not complications free and often requires an additional intervention for the assessment of possible complications an…

  15. Article

    The Effect of Pregabalin on the Quality of Life in Patients with Central Post-Stroke Pain

    Bangunawati Rahajeng, Zullies Ikawati, Tri Murti Andayani, Iwan Dwiprahasto

    pp. 222–225 · DOI: 10.5530/jyp.2018.10.49 · Published

    Objective: Pregabalin is an off-label drug used to reduce central neuropathy pain that often accompanies and affects the quality of life in central poststroke pain (CPSP). This study was conducted to determine the effect…

  16. Article

    Assessment of Therapeutic Outcome and Medication Adherence in Diabetics Consumed Insulin, Oral Hypoglycemics and Poly Herbal Drugs

    Krishnan Karthickeyan, Perumal Panneerselvam, Thomas Abhilash, Ramalingam Kameswaran, Kandaswamy Krishnaveni, Sivannan Srinivasan

    pp. 226–230 · DOI: 10.5530/jyp.2018.10.50 · Published

    Introduction: The overwhelming of consumption of antidiabetes poly herbal products (PHP) would influence the outcomes of hyperglycemia management. The underlying reasons were yet to be reveled; thought to be the herb-dru…

  17. Article

    Essential Medication Prescription and Associated Maternal Characteristic among Hospitalized Pregnant Women: A Retrospective Population Based Study

    Roopa Satyanarayan Basutkar, Raja D, Divya P, Sangram Das, Ponnusankar S S

    pp. 231–236 · DOI: 10.5530/jyp.2018.10.51 · Published

    Objective: There are limitations of Food and Drug Administration pregnancy risk classification system and pregnancy information, surplus resources are essential to evaluate the safety and to assess the risk-benefit ratio…

Short Communication

  1. Communication

    Analysis of Potential Drug Interactions in Brazilian Mental Health Services: Prevalence and Associated Factors

    Sarah Nascimento Silva, Marina Guimarães Lima, Cristina Mariano Ruas

    pp. 237–240 · DOI: 10.5530/jyp.2018.10.52 · Published

    Background: In the mental health field, the psychotropic polypharmacy is frequently observed, a significant risk factor for the occurrence of drug interactions. Objective: Identify potential drug interactions on the pres…

Letter to editor

  1. Article

    Discovery of a Series of 5-benzylidene-1, 3-thiazolidine-2, 4-dione-linked Chalcone Hybrids as a Novel Class of 5-Lipoxygenase (5-LO) Inhibitors

    Vasudeva Rao Avupati, Yuawa Rani, Ashwinder Singh

    pp. 241–242 · DOI: 10.5530/jyp.2018.10.53 · Published

    In mammals, lipoxygenases (LOXs) are enzymes containing iron that are biological targets for essential fatty acids. These fatty acids are eico sanoids, derived from arachidonic acid, play important roles in im plication …

Case Report

  1. Article

    Atropine Induced Delirium in Organophosphate (OP) Insecticide Poisoning: A Case Report

    Khayati Moudgil, Tenzin Tsundue, Ponnusankar Sivasankaran

    pp. 243–245 · DOI: 10.5530/jyp.2018.10.54 · Published

    Delirium is a condition associated with disturbances in mental abilities attributing to the reduced awareness of one’s environment. The onset of delirium is usually rapid, which may last for hours or even few days. Organ…

  2. Article

    Drug Delivery Tailored for the Need– Case Series of Oral Lichen Planus

    Archana Venugopal, T.N. Uma Maheswari

    pp. 246–248 · DOI: 10.5530/jyp.2018.10.55 · Published

    Lichen planus is an inflammatory mucocutaneous disorder. The pathogenesis of lichen planus is predominantly T cell mediated. The condition is associated with it are hepatitis C, graft versus host disease, medications [an…