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Article

Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata

Andréia da Silva Fernandes1★, Alexandre Santos Alencar1, Heitor Evangelista1, José Luiz Mazzei1★ Corresponding author

  1. 1Israel Felzenszwalb Department of Biophysics and Biometry, Institute of Biology Roberto Alcantara Gomes, Rio de Janeiro State University, Brazil.
  2. 2Platform of Analytical Chemistry, Farmanguinhos, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.

CORRESPONDENCE

Andréia da Silva Fernandes

Israel Felzenszwalb Department of Biophysics and Biometry, Institute of Biology Roberto Alcantara Gomes, Rio de Janeiro State University, Brazil.

mazzei@pq.cnpq.br

Received: 17-01-2014; Revised: 27-04-2014.

Volume 11, Issue 41 · pp. 38–43 · PUBLISHED 21 January 2015 · DOI: 10.4103/0973-1296.149701

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ABSTRACT

Background: The Antarctic moss Sanionia uncinata (Hedw.) Loeske has shown high ultraviolet (UV)‑absorbers content after exposition to high levels of UV‑B radiation and can be an important source of antioxidants. Objective: The aim was to investigate photoprotection and mutagenicity by the aqueous extract (AE) and hydroethanolic extract (HE) from the Antarctic moss S. uncinata. Materials and Methods: Photoprotective activities were determined through survival curves of Escherichia coli strains, after UV irradiation in an aqueous solution of thymine and in vitro sun protection factor (SPF). The Salmonella/microsome assays were applied to assess the mutagenicity. Results: Both extracts induced photoprotection against UV‑C radiation. The AE showed a higher protection than the hydroethanolic one against UV‑induced thymine dimerization. The SPFs were low in both extracts. In association to benzophenone‑3 a significant increase in the SPF was detected for the AE, and a significant decrease was induced by the HE. No mutagenicity was found in the both extracts. Furthermore, it was observed absence of cytotoxicity. Conclusion: Water‑extractable compounds seem to contribute on photoprotection of this Antarctic moss.

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    Fernandes, A. D. S., Alencar, A. S., Evangelista, H., & Mazzei, J. L. (2015). Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata. Pharmacognosy Magazine, 11(41), 38–43. https://doi.org/10.4103/0973-1296.149701