Volume 11, Issue 41

1. Article

   Simultaneous determination of nine analytes in Clausena harmandiana Pierre. by new developed high‑performance liquid chromatography method and the influence of locations in Thailand on level of nordentatin and dentatin

   Jinda Wangboonskul, Amolnat Tunsirikongkon, Watikan Sasithornwetchakun

   pp. 1–7 · DOI: 10.4103/0973-1296.149666 · Published 21 January 2015

   Background: Clausena harmandiana Pierre. (CH) contains various bioactive analytes with pharmacological benefits. Most researches were focused on carbazole analytes determined by isocratic high‑performance liquid chromato…

2. Article

   Flavonoid profiles of three Bupleurum species and in vitro hepatoprotective activity of Bupleurum flavum Forsk.

   Reneta Gevrenova, Magdalena Kondeva‑Burdina, Nikolay Denkov, Dimitrina Zheleva‑Dimitrova

   pp. 14–23 · DOI: 10.4103/0973-1296.149680 · Published 21 January 2015

   Background: Bupleurum L. (Aspiaceae) species are used as herbal remedy in Chinese traditional medicine. Objective: The aim was to investigate the flavonoids in three annual European Bupleurum species, including B. balden…

3. Article

   Hepatoprotective and antibacterial activity of Lippia nodiflora Linn. against lipopolysaccharides on HepG2 cells

   S. Arumanayagam, M. Arunmani

   pp. 24–31 · DOI: 10.4103/0973-1296.149689 · Published 21 January 2015

   Background: Lippia nodiflora (LN) Linn is a small herb distributed throughout the world. The plant extracts of LN is used traditionally as an analgesic, anti‑inflammatory, antioxidant, antibacterial, antimicrobial, antip…

4. Article

   Peptides from two sanguinovorous leeches analyzed by ultra‑performance liquid chromatography coupled with electrospray ionization quadrupole time‑of‑flight mass spectrometric detector

   Ling Xiao, Jing Nie, Danping Li, Keli Chen

   pp. 32–37 · DOI: 10.4103/0973-1296.149699 · Published 21 January 2015

   Background: Hirudo nipponica Whitman and Poecilobdella manillensis Lesson fall into the family of Hirudinidae Whitman, both of them are sanguinovorous leeches and used a anticoagulant medicines in China. Their medicinal …

5. Article

   Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata

   Andréia da Silva Fernandes, Alexandre Santos Alencar, Heitor Evangelista, José Luiz Mazzei

   pp. 38–43 · DOI: 10.4103/0973-1296.149701 · Published 21 January 2015

   Background: The Antarctic moss Sanionia uncinata (Hedw.) Loeske has shown high ultraviolet (UV)‑absorbers content after exposition to high levels of UV‑B radiation and can be an important source of antioxidants. Objectiv…

6. Article

   Terpenoids from Ligularia kangtingensis

   Jin Tian, Guang‑Bo Xie, Ya Xie, Tie‑Nan Li

   pp. 44–47 · DOI: 10.4103/0973-1296.149702 · Published 21 January 2015

   Background: Ligularia kangtingensis, a species from the genus Ligularia (Compositae), is an indigenous plant in Southwest China and more than 20 species in this genus have been used as folk medicines in China. Objective:…

7. Article

   Hepatoprotective constituents of Firmiana simplex stem bark against ethanol insult to primary rat hepatocytes

   Jung Wha Kim, Heejung Yang, Namki Cho, Bitnarae Kim, Young Choong Kim, Sang Hyun Sung

   pp. 55–60 · DOI: 10.4103/0973-1296.149704 · Published 21 January 2015

   Background: Ethanol causes hepatic cellular damage by alterations in biological functions. This study evaluated the hepatoprotective potential of the methanolic extract originating from Firmiana simplex (Sterculiaceae) s…

8. Article

   Simultaneous Quantitative Determination of 12 Active Components in Yuanhu Zhitong Prescription by RP‑HPLC Coupled with Photodiode Array Detection

   Xiaokai Zhang, Song Zhang, Qian Yang, Wei Cao, Yanhua Xie, Pengcheng Qiu, Siwang Wang

   pp. 61–68 · DOI: 10.4103/0973-1296.149705 · Published 21 January 2015

   Background: Yuanhu Zhitong prescription (YZP) is a famous traditional Chinese medicine formula, which is officially recorded in Chinese Pharmacopoeia for the treatment of stomach pain, hypochondriac pain, headache and dy…

9. Article

   Studies on the active constituents in radix salviae miltiorrhizae and their protective effects on cerebral ischemia reperfusion injury and its mechanism

   Yan‑hui Li, Feng‑yun Wang, Chun‑qing Feng, Xia‑feng Yang

   pp. 69–73 · DOI: 10.4103/0973-1296.149706 · Published 21 January 2015

   Background: To extract, purify and identify the active constituents in ethanol extract of Radix Salviae Miltiorrhizae, and to analyze the protective effects of tanshinone IIA on cerebral ischemia‑reperfusion injury in ra…

10. Article

    The molecular basis of the antidiabetic action of quercetin in cultured skeletal muscle cells and hepatocytes

    Hoda M. Eid, Abir Nachar, Farah Thong, Gary Sweeney, Pierre S. Haddad

    pp. 74–81 · DOI: 10.4103/0973-1296.149708 · Published 21 January 2015

    Background: Quercetin is universally distributed in the plant kingdom and is the most abundant flavonoid in the human diet. In a previous study, we have reported that quercetin stimulated glucose uptake in cultured C2C12…

11. Article

    Effects of iriflophenone 3‑C‑β‑glucoside on fasting blood glucose level and glucose uptake

    Ratree Pranakhon, Chantana Aromdee, Patchareewan Pannangpetch

    pp. 82–89 · DOI: 10.4103/0973-1296.149711 · Published 21 January 2015

    Background: One of the biological activities of agar wood (Aquilaria sinensis Lour., Thymelaeaceae), is anti‑hyperglycemic activity. The methanolic extract (ME) was proven to possess the fasting blood glucose activity in…

12. Article

    Spectrophotometric determination of the total flavonoid content in Ocimum basilicum L. (Lamiaceae) leaves

    Layzon Antonio Lemos da Silva, Bianca Ramos Pezzini, Luciano Soares

    pp. 96–101 · DOI: 10.4103/0973-1296.149721 · Published 21 January 2015

    Background: The chemical characterization is essential to validate the pharmaceutical use of vegetable raw materials. Ultraviolet spectroscopy is an important technique to determine flavonoids, which are important active…

13. Article

    Bioactive fraction of Saraca indica prevents diabetes induced cataractogenesis: An aldose reductase inhibitory activity

    Gauresh Somani, Sadhana Sathaye

    pp. 102–110 · DOI: 10.4103/0973-1296.149722 · Published 21 January 2015

    Background: The present study was designed to investigate the effect of Saraca indica (SI) flowers extract and different bioactive fraction on in vitro aldose reductase (AR) inhibitory activity, high glucose‑induced cata…

14. Article

    Hepatoprotective and in vivo antioxidant activity of Olax subscorpioidea Oliv. (Olacaceae) and Distemonathus benthamianus Baill. (Caesalpiniaceae)

    Kouassi Konan, N’dah Kouamé Justin, Boyvin Lydie, Méité Souleymane, Yapo Adou Francis

    pp. 111–116 · DOI: 10.4103/0973-1296.149723 · Published 21 January 2015

    Background: Liver diseases are on rise and remain a serious health problem. Olax subscorpioidea and Distemonanthus benthamianus are two plants used in Ivorian traditional medicine in the treatment of many diseases includ…

15. Article

    Antihyperglycemic effects of Pandanus amaryllifolius Roxb. leaf extract

    Anchalee Chiabchalard, Nattakarn Nooron

    pp. 117–122 · DOI: 10.4103/0973-1296.149724 · Published 21 January 2015

    Background: Diabetes mellitus is one of the leading chronic diseases worldwide. In patients with poor glycemic control, high blood glucose level may lead to other life‑threatening complications. Pandanus amaryllifolius R…

16. Article

    Gastroprotective effect of alpha‑pinene and its correlation with antiulcerogenic activity of essential oils obtained from Hyptis species Marcelo de Almeida Pinheiro, Rafael Matos Magalhães, Danielle Mesquita Torres,

    Rodrigo Cardoso Cavalcante, Francisca Sheila Xavier Mota, Emanuela Maria Araújo Oliveira Coelho, Henrique Pires Moreira, Glauber Cruz Lima, Pamella Cristina da Costa Araújo, José Henrique Leal Cardoso, Andrelina Noronha Coelho de Souza, Lúcio Ricardo Leite Diniz

    pp. 123–130 · DOI: 10.4103/0973-1296.149725 · Published 21 January 2015

    Background: Αlpha‑pinene (α‑pinene) is a monoterpene commonly found in essential oils with gastroprotective activity obtained from diverse medicinal plants, including Hyptis species. The genus Hyptis (lamiaceae) consists…

17. Article

    Isolation and purification of schisandrol A from the stems of Schisandra chinensis and cytotoxicity against human hepatocarcinoma cell lines

    Lijie Zhu, Bin Li, Xiuying Liu, Guohui Huang, Xianjun Meng

    pp. 131–135 · DOI: 10.4103/0973-1296.149726 · Published 21 January 2015

    Background: Schisandrol A, a lignan with anticancer effects, is one of the representative components that identifies Schisandra chinensis. Objective: A method for purifying schisandrol A from the stems of S. chinensis wa…

18. Article

    AMPK‑activated protein kinase activation by Impatiens balsamina L. is related to apoptosis in HSC‑2 human oral cancer cells

    Ji‑Ae Shin, Ki Han Kwon, Sung‑Dae Cho

    pp. 136–142 · DOI: 10.4103/0973-1296.149728 · Published 21 January 2015

    Objective: In the present study, we investigated the efficacy of a methanol extract from Impatiens balsamina L. (MEIB) against HSC‑2 human oral cancer cells. Materials and Methods: The anti‑cancer efficacies of MEIB were…

19. Article

    Effects of aqueous extract from Silybum marianum on adenosine deaminase activity in cancerous and noncancerous human gastric and colon tissues

    Bahadır Öztürk, Ender Hilmi Kocaoğlu, Zahide Esra Durak

    pp. 143–146 · DOI: 10.4103/0973-1296.149729 · Published 2015

    Objective: Investigation of possible effects of Silybum marianum extract (SME) on adenosine deaminase (ADA) activity in cancerous and noncancerous human gastric and colon tissues to obtain information about possible mech…

20. Article

    Physicochemical characterization, fatty acid composition, and thermal analysis of Bertholletia excelsa HBK oil Marcos Antônio Pena Muniz, Marina Nídia Ferreira dos Santos, Carlos Emmerson Ferreira da

    Costa Costa, Luiz Morais, Maria Louze Nobre Lamarão, Roseane Maria Ribeiro-Costa

    pp. 147–151 · DOI: 10.4103/0973-1296.149730 · Published 21 January 2015

21. Article

    Microsatellite analysis in the genome of Acanthaceae: An in silico approach

    Priyadharsini Kaliswamy, Srividhya Vellingiri, Bharathi Nathan, Saravanakumar Selvaraj

    pp. 152–156 · DOI: 10.4103/0973-1296.149731 · Published 21 January 2015

    Background: Acanthaceae is one of the advanced and specialized families with conventionally used medicinal plants. Simple sequence repeats (SSRs) play a major role as molecular markers for genome analysis and plant breed…

22. Article

    Development and validation of an high‑performance liquid chromatography‑diode array detector method for the simultaneous determination of six phenolic compounds in abnormal savda munziq decoction

    Shuge Tian, Wenxian Liu, Feng Liu, Xuejia Zhang, Halmuart Upur

    pp. 157–162 · DOI: 10.4103/0973-1296.149732 · Published 21 January 2015

    Aims: Given the high‑effectiveness and low‑toxicity of abnormal savda munziq (ASMQ), its herbal formulation has long been used in traditional Uyghur medicine to treat complex diseases, such as cancer, diabetes, and cardi…

23. Article

    Vasorelaxant and blood pressure lowering effects of alchemilla vulgaris: A comparative study of methanol and aqueous extracts

    S. Takır, I. H. Altun, B. Sezgi, S. Süzgeç‑Selçuk, A. Mat, B. S. Uydeş‑Doğan

    pp. 163–169 · DOI: 10.4103/0973-1296.149733 · Published 21 January 2015

    Background: In the last decade, a growing interest particularly in determining the cardiovascular effects of herbal extracts took place among researchers. Objective: Herein, we aimed to investigate the microvascular and …

24. Article

    Obtainment of pellets using the standardized liquid extract of Brosimum gaudichaudii Trécul (Moraceae)

    Omar Paulino Silva Filho, Leandra Almeida Ribeiro Oliveira, Frederico Severino Martins, Leonardo Luiz Borges, Osvaldo de Freitas, Edemilson Cardoso da Conceição

    pp. 170–175 · DOI: 10.4103/0973-1296.149734 · Published 21 January 2015

    Background: The standardized liquid extract of Brosimum gaudichaudii Trécul is an alternative for the treatment of vitiligo. There is a shortage of solid oral dosage forms developed from standardized extracts of this pla…

25. Article

    Chromatographic method for determination of the free amino acid content of chamomile flowers

    Xiaoli Ma, Dongsheng Zhao, Xinxia Li, Lei Meng

    pp. 176–179 · DOI: 10.4103/0973-1296.149735 · Published 21 January 2015

    Objective: To determine the free amino acid contents of chamomile flowers using reverse‑phase high‑performance column chromatography preceded by pre‑column derivatization with 6‑aminoquinolyl‑N‑hydroxysuccinimidyl carbam…

26. Article

    Estimation of Costunolide and Dehydrocostus Lactone in Saussurea lappa and its Polyherbal Formulations followed by their Stability Studies Using HPLC‑DAD

    P.R. Rao Vadaparthi, K. Kumar, Vanka Uma Maheswara Sarma, Qazi Altaf Hussain, K. Suresh Babu

    pp. 180–190 · DOI: 10.4103/0973-1296.149736 · Published 21 January 2015

    Background: Saussurea lappa is one of the popular Ayurvedic herb; costunolide and dehydrocostus lactones are well‑known sesquiterpene lactones contained in many plants used as popular herbs, such as S. lappa, and have be…

27. Article

    A New Lignan Glucoside from Lagochilus ilicifolius

    Qian Jing-Shi, Zhang Cheng-Gang, Wang Wei, Zhang Ting, Xu Hong, Chou Gui-Xin

    pp. 191–195 · DOI: 10.4103/0973-1296.149738 · Published 21 January 2015

    Background: The whole herb of Lagochilus ilicifolius has been used as a folk medicine for treating hemostatic, inflammation and ulcer in China. There were only limited reports on its chemical constituents, and no reports…

28. Article

    Qualitative and quantitative determination of 15 main active constituents in Fructus Sophorae pill by liquid chromatography tandem mass spectrometry

    Xu‑ran Zhi, Zhi‑yong Zhang, Pei‑pei Jia, Xiao‑xu Zhang, Lin Yuan, Ning Sheng, Lan‑tong Zhang

    pp. 196–207 · DOI: 10.4103/0973-1296.149739 · Published 21 January 2015

    Background: Fructus Sophorae pill, one of the traditional Chinese medicine, was widely used for hemorrhoids, hypertension and odontalgia. This paper describes a sensitive and specific assay for the determination of the 1…

29. Article

    A Comparison of the Antimicrobial Activity and Toxicity of Six Combretum and Two Terminalia Species from Southern Africa

    I. E. Cock, S.F. Van Vuuren

    pp. 208–218 · DOI: 10.4103/0973-1296.149740 · Published 21 January 2015

    Background: Plants of the family Combretaceae are amongst the most widely used plants for traditional medicinal purposes in southern Africa. In particular, many species of Combretum and Terminalia are used for their anti…

30. Article

    Promoting effect of triterpenoid compound from Agrimonia pilosa Ledeb on preadipocytes differentiation via up‑regulation of PPARγ expression

    Tingwang Guo, Liancai Zhu, Jun Tan, Xuemei Zhou, Ling Xiao, Xi Liu, Bochu Wang

    pp. 219–225 · DOI: 10.4103/0973-1296.149741 · Published 21 January 2015

    Background: Agrimonia Pilosa Ledeb (APL), a traditional Chinese medicine, has been reported a variety of biological activities, including treating T2DM. Objective: Triterpenoid compound (TC) was collected from APL. The a…

31. Article

    Technical aspects on production of fluid extract from Brosimum gaudichaudii Trécul roots

    Frederico Severino Martins, Henrique Pascoa, José Realino de Paula, Edemilson Cardoso da Conceição

    pp. 226–231 · DOI: 10.4103/0973-1296.149742 · Published 21 January 2015

ORIGINAL ARTICLE

1. Article

   Near-infrared for on-line determination of quality parameter of Sophora japonica L. (formula particles): From lab investigation to pilot-scale extraction process

   Yang Li, Xinyuan Shi, Zhisheng Wu, Mingye Guo, Bing Xu, Xiaoning Pan, Qun Ma, Yanjiang Qiao

   pp. 8–9 · DOI: 10.4103/0973-1296.149674 · Published 21 January 2015

   Background: Extraction process of dried flowers of formula particles should be investigated from lab investigation to pilot‑scale because of good water absorbing capacity and obscure active pharmaceutical ingredients (AP…

2. Article

   Antioxidant and anti‑lipoxygenase activities of extracts from different parts of Lavatera cretica L. grown in Algarve (Portugal)

   Soumeya Ben-Nasr, Smail Aazza, Wissem Mnif, Maria da Graça Costa Miguel

   pp. 48–48 · DOI: 10.4103/0973-1296.149743 · Published 21 January 2015

   Background: Lavatera cretica L. was used in folk medicine as anti‑inflammatory among other applications. As inflammation is many times associated with oxidative processes, the aim of the present work was to evaluate the …

3. Article

   Evaluating Nothapodytes nimmoniana population from three localities of Western Ghats using camptothecin as phytochemical marker and selection of elites using a new-content range chart method

   Gireesh Ankad, Vinayak Upadhya, Sandeep R. Pai, Mansingraj S. Nimbalkar, Harsha V. Hegde, Rajesh K. Joshi, Sanjiva D. Kholkute

   pp. 90–91 · DOI: 10.4103/0973-1296.149712 · Published 21 January 2015

   Background: Nothapodytes nimmoniana (Grah.) Mabb. is a high valued medicinal plant endemic to Western Ghats of India, distributed in fragmented populations. The plant is valued for potent anticancer drug camptothecin (CP…