Volume 13, Issue 52

13 November 2017 · pp. 535–743 · 32 articles

Volume: 13
Issue: 52
Published: 13 November 2017
Pages: 535–743
Articles: 32
Sections: 2
ISSN: Print - 0973-1296, Online - 0976-4062
Journal: PM

Original Article ORIGINAL ARTICLE

In this issue

Original Article

Article
Identification of Hepatoprotective Constituents in Limonium tetragonum and Development of Simultaneous Analysis Method using High‑performance Liquid Chromatography
Jae Sun Lee, Yun Na Kim, Na‑Hyun Kim, Jeong‑Doo Heo, Min Hye Yang, Jung‑Rae Rho, Eun Ju Jeong
pp. 535–541 · DOI: 10.4103/pm.pm_477_16 · Published 13 November 2017
Background: Limonium tetragonum, a naturally salt‑tolerant halophyte, has been studied recently and is of much interest to researchers due to its potent antioxidant and hepatoprotective activities. Objective: In the pres…
Article
Gastroprotective and Ulcer Healing Effects of Camel Milk and Urine in HCl/EtOH, Non‑steroidal Anti‑inflammatory Drugs (Indomethacin), and Water‑Restraint Stress‑induced Ulcer in Rats
Zijuan Hu, Xiaoman Chang, Qing Pan, Kebin Gu, Patrick Nwabueze Okechukwu
pp. 559–565 · DOI: 10.4103/pm.pm_135_17 · Published 13 November 2017
Background: Camel milk has been reportedly used to treat dropsy, jaundice, tuberculosis, and diabetes while camel urine is used to treat diarrhea and cancer. However, there is no scientific evidence on the antiulcer acti…
Article
Simultaneous Determination of Ten Constituents in Chaiqin Qingning Capsule by High‑performance Liquid Chromatography Coupled with Triple‑quadrupole Mass Spectrometry
Ting Yu Li, Xiao Kui Huo, Lu Zheng, Chao Wang, Hai Jian Cong, Ting Xiang, Lin Zhang, Bao Jing Zhang, Shan Shan Huang, Bin Wu, Xin Yu Li
pp. 566–570 · DOI: 10.4103/pm.pm_81_17 · Published 13 November 2017
Background: Chaiqin Qingning Capsule (CQQNC) was a prescription of Traditional Chinese Medicine with the effects of clearing away heat and removing toxin, harmonizing the exterior and interior, it was widely used in Asia…
Article
Antitumor Effects of Ethanol Extracts from Hyptis Rhomboidea in H22 Tumor‑bearing Mice
Hong-Xin Cui, Lu Tang, Fang-Rong Cheng, Ke Yuan
pp. 571–575 · DOI: 10.4103/pm.pm_314_16 · Published 13 November 2017
Background: Research the antitumor effects of ethanol extracts from Hyptis rhomboidea in H22 tumor‑bearing mice. At the fist‑stage of the experiments, the research team took MTT method to measure the antitumor activity i…
Article
Antioxidant and Inhibitory Effects of Saponin Extracts from Dianthus basuticus Burtt Davy on Key Enzymes Implicated in Type 2 Diabetes In vitro
Mikhail Olugbemiro Nafiu, Anofi Omotayo Tom Ashafa
pp. 576–582 · DOI: 10.4103/pm.pm_583_16 · Published 13 November 2017
Context: Dianthus basuticus is a plant of South African origin with various acclaimed pharmaceutical potentials. Aims: This study explored the antioxidant and antidiabetic activities of saponin extract from D. basuticus …
Article
In vitro and In vivo Activity of Myrsine africana on Elastase Inhibition and Anti‑wrinkle Activity
Namrita Lall, Navneet Kishore, Bianca Fibrich, Isa Anina Lambrechts
pp. 583–589 · DOI: 10.4103/pm.pm_145_17 · Published 13 November 2017
Background: Myrsine africana (MA) is a plant traditionally used in South Africa to treat various diseases. Objective: The ethanolic extract of MA, was used for in vitro and in vivo studies to determine its elastase inhib…
Article
α‑Glucosidase Inhibitory Activity from Ethyl Acetate Extract of Antidesma bunius (L.) Spreng Stem Bark Containing Triterpenoids
Marista Gilang Mauldina, Rani Sauriasari, Berna Elya
pp. 590–594 · DOI: 10.4103/pm.pm_25_17 · Published 13 November 2017
Background: Buni (Antidesma bunius [L.] Spreng) has been used as a traditional antidiabetic agent in Asia. Objective: The mechanism of antidiabetic properties was studied in this study by determine its α‑glucosidase inhi…
Article
Anti-cancer Effects of Polyphenolic Compounds in Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor-resistant Non-small Cell Lung Cancer
Hyungmin Jeong, Ai N. H. Phan, Jong‑Whan Choi
pp. 595–599 · DOI: 10.4103/pm.pm_535_16 · Published 13 November 2017
Background: Polyphenolic phytochemicals are natural compounds, easily found in fruits and vegetables. Importantly, polyphenols have been intensively studied as excellent antioxidant activity which contributes to anticanc…
Article
Extraction of Chelerythrine and its Effects on Pathogenic Fungus Spore Germination
Qinghui Wei, Min Zhao, Xiaoyan Li
pp. 600–606 · DOI: 10.4103/pm.pm_545_16 · Published 13 November 2017
Background: Chemical fungicides are widely used to control crop diseases, but these chemicals have adverse effects. They destroy the ecological environment and even have toxic effects on human beings. In this context, th…
Article
Helichrysetin Induces DNA Damage that Triggers JNK-Mediated Apoptosis in Ca Ski Cells
Ho Yen Fong, Sri Nurestri Abd Malek, Hui Shin Yee, Saiful Anuar Karsani
pp. 607–612 · DOI: 10.4103/pm.pm_53_17 · Published 13 November 2017
Background: Cervical cancer has become one of the most common cancers in women and currently available treatment options for cervical cancer are very limited. Naturally occurring chalcones and its derivatives have been s…
Article
In vitro and In vivo Postprandial Glycemic Activity of Citrus limetta Peel Flour
José Miguel Flores‑Fernández, Carla Patricia Barragán‑Álvarez, Nestor Emmanuel Díaz‑Martínez, Socorro Villanueva‑Rodríguez, Eduardo Padilla‑Camberos
pp. 613–616 · DOI: 10.4103/pm.pm_158_17 · Published 13 November 2017
Background: Previous studies of Citrus spp. peel have shown hypoglycemic and antioxidant activities. Citrus limetta has been studied for its therapeutic properties. Diabetes mellitus (DM) is a health problem in Mexico an…
Article
Mice Behavioral Phenotype Changes after Administration of Anani (Symphonia globulifera, Clusiaceae), an Alternative Latin American and African Medicine
Ivana Barbosa Suffredini, Mateus Luís Barradas Paciencia, Ingrit E. C. Díaz, Sergio Alexandre Frana, Maria Martha Bernardi
pp. 617–626 · DOI: 10.4103/pm.pm_168_17 · Published 13 November 2017
Background: Anani, (Symphonia globulifera, Clusiaceae), known as chewstick, is a traditional plant occurring in Africa and in Central and South Americas that is used against parasites and microorganisms. Although its use…
Article
Influence of Flavonoids on Mechanism of Modulation of Insulin Secretion
Juliana Mikaelly Dias Soares, Ana Ediléia Barbosa Pereira Leal, Juliane Cabral Silva, Jackson R. G. S. Almeida
pp. 639–646 · DOI: 10.4103/pm.pm_87_17 · Published 13 November 2017
Background: The development of alternatives for insulin secretion control in vivo or in vitro represents an important aspect to be investigated. In this direction, natural products have been progressively explored with t…
Article
Antioxidant, Acetylcholinesterase, Butyrylcholinesterase, and α‑glucosidase Inhibitory Activities of Corchorus depressus
Samina Afzal, Bashir Ahmad Chaudhry, Ashfaq Ahmad, Muhammad Uzair, Khurram Afzal
pp. 647–651 · DOI: 10.4103/pm.pm_95_17 · Published 13 November 2017
Background: Corchorus depressus (Cd) commonly known as Boa‑phalee belonging to the family Tiliaceae having 50 genera and 450 species. Cd is not among the studied medicinal agent despite its potential in ethnopharmacology…
Article
Superoxide Scavenging and Antiglycation Activity of Rhinacanthins‑rich Extract Obtained from the Leaves of Rhinacanthus nasutus
Muhammad Ajmal Shah, Haji Muhammad, Yasir Mehmood, Ruqaiya Khalil, Zaheer Ul‑Haq, Pharkphoom Panichayupakaranant
pp. 652–658 · DOI: 10.4103/pm.pm_196_17 · Published 13 November 2017
Background: Oxidative stress and nonenzymatic protein glycation lead to serious diabetic complications that increase the risk of mortality. Rhinacanthus nasutus leaf crude extracts are previously reported for their antid…
Article
Comparative Proteomic Analysis of Three Gelatinous Chinese Medicines and Their Authentications by Tryptic‑digested Peptides Profiling using Matrix‑assisted Laser Desorption/ Ionization‑time of Flight/Time of Flight Mass Spectrometry
Huan Yang, Jie Zheng, Hai‑yan Wang, Nan Li, Ya‑ya Yang, Yu‑ping Shen
pp. 663–667 · DOI: 10.4103/pm.pm_54_17 · Published 13 November 2017
Background: Gelatinous Chinese medicines (GCMs) including Asini Corii Colla, Testudinis Carapacis ET Plastri Colla, and Cervi Cornus Colla, were made from reptile shell or mammalian skin or deer horn, and consumed as a p…
Article
Brazilian Cerrado Qualea grandiflora Mart. Leaves Exhibit Antiplasmodial and Trypanocidal Activities In vitro
Thuany de Moura Cordeiro, Fabian Borghetti, Sarah C. Caldas Oliveira, Izabela Marques Dourado Bastos, Jaime Martins de Santana, Philippe Grellier, Sébastien Charneau
pp. 668–672 · DOI: 10.4103/pm.pm_100_17 · Published 13 November 2017
Background: The rapid spread of drug‑resistant strains of protozoan parasites required the urgent need for new effective drugs. Natural products offer a variety of chemical structures, which make them a valuable source o…
Article
Two New Phenolic Glycosides from the Aerial Part of Dryopteris erythrosora
Guijae Yoo, SeonJu Park, Heejung Yang, Xuan Nhiem Nguyen, Nanyoung Kim, Jun Hyung Park, Seung Hyun Kim
pp. 673–676 · DOI: 10.4103/pm.pm_326_16 · Published 13 November 2017
Background: Dryopteris erythrosora (D.C. Eaton) Kuntze is a species of fern in the family of Dryopteridaceae, which is distributed throughout East Asia. The genus Dryopteris has been used as traditional medicine, especia…
Article
Amelioration of Intestinal Barrier Dysfunction by Berberine in the Treatment of Nonalcoholic Fatty Liver Disease in Rats
Donghao Li, Jimin Zheng, Yiting Hu, Hongtao Hou, Shurong Hao, Na Liu, Yuzhen Wang
pp. 677–682 · DOI: 10.4103/pm.pm_584_16 · Published 13 November 2017
Objective: To investigate the effect of berberine (BBR) on intestinal barrier function in nonalcoholic fat liver disease (NAFLD) in rats. Materials and Methods: Rats were divided into three groups: normal diet group (con…
Article
Toxicity and Detoxification Effects of Herbal Caowu via Ultra Performance Liquid Chromatography/Mass Spectrometry Metabolomics Analyzed using Pattern Recognition Method
Yan Yan, Aihua Zhang, Hui Dong, Guangli Yan, Hui Sun, Xiuhong Wu, Ying Han, Xijun Wang
pp. 683–692 · DOI: 10.4103/pm.pm_475_16 · Published 13 November 2017
Background: Caowu (Radix Aconiti kusnezoffii, CW), the root of Aconitum kusnezoffii Reichb., has widely used clinically in rheumatic arthritis, painful joints, and tumors for thousands of years. However, the toxicity of …
Article
Hispidulin-7-O-Neohesperidoside from Cirsium japonicum var. ussuriense Attenuates the Production of Inflammatory Mediators in LPS-Induced Raw 264.7 Cells and HT-29 Cells
Jong Cheol Park, Hyunji Yoo, Cho Een Kim, Sun-Yup Shim, Mina Lee
pp. 707–711 · DOI: 10.4103/0973-1296.218116 · Published 13 November 2017
Background: Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract and involves secretion of inflammatory mediators. The flavone diglycoside hispidulin-7-O- neohesperidosi…
Article
In Vitro Bioassay‑guided Isolation of Radioprotective Fractions from Extracts of Pinus koraiensis Bark
Keli Yun, Jian-Hai Bai, ZhenYu Wang
pp. 712–718 · DOI: 10.4103/pm.pm_409_16 · Published 18 July 2017
Objective: The aim of this study was to evaluate radioprotective effect of extracts of Pinus koraiensis bark and its fractions on rat splenocytes by using bioassay‑guided isolation in order to obtain the best active frac…
Article
Contribution of the Glucosinolate Fraction to the Overall Antioxidant Potential, Cytoprotection against Oxidative Insult and Antimicrobial Activity of Eruca sativa Mill. Leaves Extract
Maria Fernanda Taviano, Antonietta Melchini, Angela Filocamo, Chiara Costa, Stefania Catania, Roberto Raciti, Shikha Saha, Paul Needs, Giuseppe Giovanni Bisignano, Natalizia Miceli
pp. 738–743 · DOI: 10.4103/pm.pm_245_16 · Published 13 November 2017
Background: Eruca sativa Mill. (Brassicaceae) is commonly utilized as an ingredient in salads and also as a folk remedy to treat various diseases. Objective: The objective of this study was to establish the contribution …

ORIGINAL ARTICLE

Article
Biological Activities and Cytotoxicity of Eperua oleifera Ducke Oil-resin
Fernanda Torlania Alves Gomes, Ana Paula de Araújo Boleti, Lidiam M. Leandro, Diego Squinello, Ellen S. P. Aranha, Marne C. Vasconcelos, Paul Cos, Valdir F. Veiga‑Junior, Emerson Silva Lima
pp. 542–52 · DOI: 10.4103/pm.pm_552_16 · Published 13 November 2017
Background: The oil‑resin of Eperua oleifera Ducke has been used in popular medicine similarly to the copaiba oil (Copaifera spp.). Objective: This study aimed to investigate the effects of the acid fraction of E. oleife…
Article
Evaluating the Feasibility of Five Candidate DNA Barcoding Loci for Philippine Lasianthus Jack (Lasiantheae: Rubiaceae)
Muhammad Jefte C. Arshed, Marcos B. Valdez, Grecebio Jonathan D. Alejandro
pp. 553–8 · DOI: 10.4103/pm.pm_1_17 · Published 13 November 2017
Introduction: The pantropical genus Lasianthus Jack is identified for high phenotypic plasticity making traditional taxonomic identification difficult. Having some members with important medicinal properties, a precise c…
Article
Bioassay-guided Isolation of Neuroprotective Fatty Acids from Nigella sativa against 1-methyl-4-phenylpyridinium-induced Neurotoxicity
Leila Hosseinzadeh, Hoda Monaghash, Farahnaz Ahmadi, Nastaran Ghiasvand, Yalda Shokoohinia
pp. 627–633 · DOI: 10.4103/pm.pm_470_16 · Published 13 November 2017
Objective: Parkinson’s disease, a slowly progressive neurological disease, is associated with degeneration of the basal ganglia of the brain and a deficiency of the neurotransmitter dopamine. The main aspects of research…
Article
Ligustilide Relieves Complete Freund’s Adjuvant-induced Mechanical Hyperalgesia through Inhibiting the Activation of Spinal c-Jun N-terminal Kinase/c-Jun Pathway in Rats
Yi-Rui Wang, Hui Xu, Min Tao, Li-Hua Xu, Xin-Chun Fu
pp. 634–638 · DOI: 10.4103/pm.pm_546_16 · Published 13 November 2017
Background: Ligustilide, an active ingredient in a traditional Chinese medicine, has anti‑inflammatory and analgesic effects. The underlying mechanisms of the anti‑inflammatory pain effects of ligustilide are not complet…
Article
Rapid Quantitative Analysis of Naringenin in the Fruit Bodies of Inonotus vaninii by Two-phase Acid Hydrolysis Followed by Reversed Phase-high Performance Liquid Chromatography-ultra Violet
Xia Guohua, Ruirong Pan, Rui Bao, Yanru Ge, Cunshan Zhou, Yuping Shen
pp. 659–662 · DOI: 10.4103/pm.pm_350_16 · Published 13 November 2017
Introduction: Sanghuang is one of mystical traditional Chinese medicines recorded earliest 2000 years ago, that included various fungi of Inonotus genus and was well-known for antitumor effect in modern medicine. Inonotu…
Article
Induction of Apoptosis by Tithonia diversifolia in Human Hepatoma Cells
Min-Ren Lu, Huey-Lan Huang, Wen-Fei Chiou, Ray-Ling Huang
pp. 702–6 · DOI: 10.4103/0973-1296.218113 · Published 13 November 2017
Background: Traditional Chinese herb Tithonia diversifolia, belonging to the Compositae family, has long been applied for the treatment of liver diseases. In recent years, many reports also indicated that it possesses he…
Article
A Study of the Anti-Cancer Effects of the Hexane Fraction of the Methanol Extract of Forsythiae Fructus
Se-Eun Lee, Chiyeon Lim, Soon-Cheol Ahn, Suin Cho
pp. 719–724 · DOI: 10.4103/0973-1296.211079 · Published 18 July 2017
Background: Forsythiae Fructus (FF) is a well-known medicinal herb derived from the dried fruits of Forsythia suspensa (Thunb.) Vahl. (Oleaceae). Recently, bioactive compounds isolated from hydrophobic solvent fractions …
Article
Evaluation of Hypolipidemic and Antioxidant Effects in Phenol-rich Fraction of Crataegus pinnatifida Fruit in Hyperlipidemia Rats and Identification of Chemical Composition by Ultra-performance Liquid Chromatography Coupled with Quadropole Time-of-flight Mass Spectrometry
Feng Shao, Lifei Gu, Huijuan Chen, Ronghua Liu, Huilian Huang, Lanying Chen, Ming Yang
pp. 725–731 · DOI: 10.4103/pm.pm_402_16 · Published 13 November 2017
Background: Hawthorn (Crataegus pinnatifida) fruit has enjoyed a great popularity as a pleasant-tasting food associated with hypolipidemic and antioxidant effects. Objective: Our aim was to screen the effective fraction …
Article
Enzyme Inhibitors Cause Multiple Effects on Accumulation of Monoterpene Indole Alkaloids in Catharanthus Roseus Cambial Meristematic Cell Cultures
Zhou Pengfei, Zhu Jianhua, Yu Rongmin, Zi Jiachen
pp. 732–7 · DOI: 10.4103/0973-1296.218121 · Published 13 November 2017
Background: Enzyme inhibitors have been used for the clarification of biosynthesis of natural products. Catharanthus roseus cambial meristematic cell (CMC) culture has been established and proved to be a better monoterpe…