Volume 13, Issue 51S

11 October 2017 · pp. 0–98 · 30 articles

Volume: 13
Issue: 51S
Published: 11 October 2017
Pages: 0–98
Articles: 30
Sections: 2
ISSN: Print - 0973-1296, Online - 0976-4062
Journal: PM

ORIGINAL ARTICLE Original Article

In this issue

ORIGINAL ARTICLE

Article
Analysis of Free Amino Acids in Different Extracts of Orthosiphon stamineus Leaves by High-Performance Liquid Chromatography Combined with Solid-Phase Extraction
Armaghan Shafaei, Nor Hidayah Ab Halim, Norhidayah Zakaria, Zhari Ismail
pp. S385–91 · DOI: 10.4103/0973-1296.216337 · Published 11 October 2017
Background: Orthosiphon stamineus (OS) Benth is a medicinal plant and native in Southeast Asia. Previous studies have shown that OS leaves possess antioxidant, cytotoxic, diuretic, antihypertensive, and uricosuric effect…
Article
A Comprehensive Study on Fast Dispersible and Slow‑Releasing Characteristic of Orange Peel Pectin in Relation to Established Synthetic Polymer
Pranati Srivastava, Mahendra Singh, Shilpi Bhargava
pp. S401–S404 · DOI: 10.4103/pm.pm_193_17 · Published 11 October 2017
Introduction: In the present work, the method to extract, isolate, and characterize orange peel pectin using soxhlation, and thereafter, the use of this polymer–polymer in the formulation of fast dispersable and slow‑rel…
Article
Investigation of Antihyperglycaemic Activity of Banana (Musa sp. Var. Nanjangud rasa bale) Flower in Normal and Diabetic Rats
Ramith Ramu, Prithvi S. Shirahatti, S. P. Dhanabal, Farhan Zameer, B. L. Dhananjaya, M. N. Nagendra Prasad
pp. S417–23 · DOI: 10.4103/0973-1296.216331 · Published 11 October 2017
Background: The vital enzymes of starch digestion and absorption are intestinal α-glucosidases and their inhibition improves postprandial hyperglycaemia, constituting an effective mode of therapy in diabetes. Objectives:…
Article
Antioxidant Phytochemicals of Opuntia ficus-indica (L.) Mill. Cladodes with Potential Anti-spasmodic Activity
Francesco Lanuzza, Francesco Occhiuto, Maria Teresa Monforte, Maria Marcella Tripodo, Valeria D’Angelo, Enza Maria Galati
pp. S424–S429 · DOI: 10.4103/pm.pm_495_16 · Published 11 October 2017
Background: Opuntia ficus‑indica (OFI) (L.) Mill. (Cactaceae), a plant widespread in dry regions of the world, shows interesting biological activities (cicatrizant, antiulcer, anti‑inflammatory, and hypolipidemic) and is…
Article
Phytochemical Compositions and In vitro Assessments of Antioxidant and Antidiabetic Potentials of Fractions from Ehretia cymosa Thonn.
Akintayo Ogundajo, Anofi Tom Ashafa
pp. S470–80 · DOI: 10.4103/pm.pm_118_17 · Published 11 October 2017
Background: Ehretia cymosa Thonn. is a popular medicinal plant used in different parts of West Africa for the treatment of various ailments including diabetes mellitus. Objective: The current study investigates bioactive…
Article
Flavonoidal Constituents, Antioxidant, Antimicrobial, and Cytotoxic Activities of Dipterygium glaucum Grown in Kingdom of Saudi Arabia
Usama Shaheen, Nagwa Abdelkader Shoeib, Abeer Temraz, Mohamed I. S. Abdelhady
pp. S484–8 · DOI: 10.4103/pm.pm_44_16 · Published 11 October 2017
Background: Dipterygium glaucum Decne. herb is one of the common traditional plants with multiple medicinal uses. Objective: To isolate the major constituents and to investigate the antioxidant, antimicrobial, and cytoto…
Article
Chalepin: A Compound from Ruta angustifolia L. Pers Exhibits Cell Cycle Arrest at S phases, Suppresses Nuclear Factor-Kappa B (NF-κB) Pathway, Signal Transducer and Activation of Transcription 3 (STAT3) Phosphorylation and Extrinsic Apoptotic Pathway in Non-small Cell Lung Cancer Carcinoma (A549)
Jaime Stella Moses Richardson, Norhaniza Aminudin, Sri Nurestri Abd Malek
pp. S489–98 · DOI: 10.4103/pm.pm_13_17 · Published 11 October 2017
Background: Plants have been a major source of inspiration in developing novel drug compounds in the treatment of various diseases that afflict human beings worldwide. Ruta angustifolia L. Pers known locally as Garuda ha…
Article
Molecular Docking Analysis of Phytic Acid and 4-hydroxyisoleucine as Cyclooxygenase-2, Microsomal Prostaglandin E Synthase-2, Tyrosinase, Human Neutrophil Elastase, Matrix Metalloproteinase-2 and -9, Xanthine Oxidase, Squalene Synthase, Nitric Oxide Synthase, Human Aldose Reductase, and Lipoxygenase Inhibitors
Radhakrishnan Narayanaswamy, Lam Kok Wai, Norhaizan Mohd Esa
pp. S512–8 · DOI: 10.4103/pm.pm_195_16 · Published 11 October 2017
Background: The phytoconstituents phytic acid and 4-hydroxyisoleucine have been reported to posses various biological properties. Objective: This prompted us to carry out the docking study on these two ligands (phytic ac…
Article
Growth-arresting Activity of Acmella Essential Oil and its Isolated Component D-Limonene (1, 8 P-Mentha Diene) against Trichophyton rubrum (Microbial Type Culture Collection 296)
Diptikanta Padhan, Smaranika Pattnaik, Ajaya Kumar Behera
pp. S555–60 · DOI: 10.4103/pm.pm_65_17 · Published 11 October 2017
Background: Spilanthes acmella is used as a remedy in toothache complaints by the tribal people of Western part of Odisha, India. Objective: The objective of this study was to study the growth‑arresting activity of an in…
Article
Are Polyunsaturated Fatty Acid Metabolites, the Protective Effect of 4‑hydroxytyrosol on Human Red Blood Cell Membranes and Oxidative Damage (4‑hydroxyalkenals) Compatible in Hypertriglyceridemic Patients?
Giuseppe Gallo, Rosalinda Bruno, Adele Taranto, Guglielmo Martino
pp. S561–6 · DOI: 10.4103/pm.pm_483_15 · Published 11 October 2017
Background: Increased levels of malondialdehyde (MDA) and 4‑hydroxynonenal (HNE) are demonstrated in plasma of uremic patients. A study showed that the comparison of erythrocytes of healthy and diseased patients (obese, …
Article
Protective Effect of Pluchea lanceolata against Aluminum Chloride-induced Neurotoxicity in Swiss Albino Mice
Ravi Mundugaru, Senthilkumar Sivanesan, Padmaja Udaykumar, Niranjan Rao, Naveen Chandra
pp. S567–72 · DOI: 10.4103/pm.pm_124_17 · Published 11 October 2017
Background: Aluminum chloride (AlCl3) is a known potent environmental neurotoxin causing progressive neurodegenerative changes in the brain. The herb Pluchea lanceolata is commonly known as “Rasana” and used as a nerve t…
Article
Inhibition of Phosphorylated c-Jun NH(2)-terminal Kinase by 2’,4’-dihydroxy-6-methoxy-3,5-dimethylchalcone Isolated from Eugenia aquea Burm f. Leaves in Jurkat T-cells
Melisa I. Barliana, Ajeng Diantini, Anas Subarnas, Rizky Abdulah, Takashi Izumi
pp. S573–7 · DOI: 10.4103/pm.pm_16_17 · Published 11 October 2017
Background: Indonesian medicinal plants have been used for their anticancer activity for decades. However, the therapeutic effects of medicinal plants have not been fully examined scientifically. As cancer is a major hea…

Original Article

Article
Bioactive Constituents, Radical Scavenging, and Antibacterial Properties of the Leaves and Stem Essential Oils from Peperomia pellucida (L.) Kunth
Sunday O. Okoh, Benson C. Iweriebor, Omobola O. Okoh, Anthony I. Okoh
pp. S392–S400 · DOI: 10.4103/pm.pm_106_17 · Published 11 October 2017
Background: Peperomia pellucida is an annual herbaceous ethnomedicinal plant used in the treatment of a variety of communicable and noncommunicable diseases in the Amazon region. Objective: The study aimed at profiling t…
Article
Acacia catechu Ethanolic Seed Extract Triggers Apoptosis of SCC‑25 Cells
Thangavelu Lakshmi, Devaraj Ezhilarasan, Upendra Nagaich, Rajagopal Vijayaragavan
pp. S405–S411 · DOI: 10.4103/pm.pm_458_16 · Published 11 October 2017
Background: Acacia catechu Willd (Fabaceae), commonly known as catechu, cachou, and black cutch, has been studied for its hepatoprotective, antipyretic, antidiarrheal, hypoglycemic, anti‑inflammatory, immunomodulatory, a…
Article
Quantitative Analysis of Benzyl Isothiocyanate in Salvadora persica Extract and Dental Care Herbal Formulations Using Reversed Phase C18 High‑Performance Liquid Chromatography Method
Maged Saad Abdel‑Kader, Kamal YT, Prawez Alam, Mohammed Hamed Alqarni, Ahmed Ibrahim Foudah
pp. S412–S416 · DOI: 10.4103/pm.pm_117_17 · Published 11 October 2017
Context: Benzyl isothiocyanate is the active antimicrobial agent in Salvadora persica (siwak) widely used in Islamic countries for oral hygiene. Aims: Quantification of benzyl isothiocyanate in the ethanol extract of S. …
Article
Biological Effect of Cynara cardunculus on Kidney Status of Hypercholesterolemic Rats
Abdullah Glil Alkushi
pp. S430–S436 · DOI: 10.4103/pm.pm_14_17 · Published 11 October 2017
Context: Cynara cardunculus or artichoke thistle belongs to the sunflower family and has a variety of cultivable forms. Historically, it was cultivated as a vegetable, but more recently, it is being used in cheese and bi…
Article
Antioxidant and Cholinesterase Inhibitory Activities of Ethyl Acetate Extract of Terminalia chebula: Cell‑free In vitro and In silico Studies
Mohamed Asik Rajmohamed, Suganthy Natarajan, Premkumar Palanisamy, Akbarsha Mohammad Abdulkader, Archunan Govindaraju
pp. S437–S445 · DOI: 10.4103/pm.pm_57_17 · Published 11 October 2017
Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder clinically characterized by memory loss and impaired cognitive function. Cholinergic enzyme deficiency and oxidative stress are the two maj…
Article
Chemical Composition, Antimicrobial and Antitumor Potentiality of Essential Oil of Ferula tingitana L. Apiaceae Grow in Libya
Waleed Elghwaji, Abeer Mohamed El‑Sayed, Kadriya S. El‑Deeb, Aly M. ElSayed
pp. S446–S451 · DOI: 10.4103/pm.pm_323_15 · Published 11 October 2017
Background: Ferula tingitana L. (Apiaceae) has been considered to have abortive and menstruation‑inducing properties. It used to treat sore throat, fever, indigestion, and pains. Objectives: The objective of this study i…
Article
Cytotoxic, Antimitotic, and Antiproliferation Studies on Rasam: A South Indian Traditional Functional Food
Agilandeswari Devarajan, M. K. Mohan Maruga Raja
pp. S452–S457 · DOI: 10.4103/pm.pm_138_17 · Published 11 October 2017
Background: Rasam is a traditional South Indian food, prepared using tamarind juice as a base, with a variety of spices. Rasam, with all its ingredients medicinally claimed for various ailments, is a functional food. Sys…
Article
The Effect of Thymoquinone on Nuclear Factor Kappa B Levels and Oxidative DNA Damage on Experimental Diabetic Rats
Ayşe Usta, Semiha Dede
pp. S458–S461 · DOI: 10.4103/pm.pm_134_17 · Published 11 October 2017
Background: Thymoquinone (TQ), the basic bioactive phytochemical constituent of seed oil of Nigella sativa, is one of these herbal drugs known for antidiabetic effects. This study was carried out to assess the effects of…
Article
Chemical Composition of Moringa oleifera Ethyl Acetate Fraction and Its Biological Activity in Diabetic Human Dermal Fibroblasts
Sivapragasam Gothai, Katyakyini Muniandy, Mazni Abu Zarin, Tan Woan Sean, S. Suresh Kumar, Murugan A. Munusamy, Sharida Fakurazi, Palanisamy Arulselvan
pp. S462–S469 · DOI: 10.4103/pm.pm_368_16 · Published 11 October 2017
Background: Moringa oleifera (MO), commonly known as the drumstick tree, is used in folklore medicine for the treatment of skin disease. Objective: The objective of this study is to evaluate the ethyl acetate (EtOAc) fra…
Article
Chromosomal Fragmentation: A Possible Marker for the Selection of High Gymnemic Acid Yielding Accessions of Gymnema sylvestre R. Br
Ashutosh Kumar Verma, Sunita Singh Dhawan
pp. S481–S483 · DOI: 10.4103/pm.pm_420_16 · Published 11 October 2017
Background: Gymnema sylvestre R. Br. a member of family Asclepiadaceae as mentioned in Indian Pharmacopoeia popular among the researchers because of stimulatory effect of its phytoconstituent on pancreatic cells and pote…
Article
Antihyperglycemic Activity of Caralluma fimbriata: An In vitro Approach
Shenai Ashwini, Roy Anitha
pp. S499–S504 · DOI: 10.4103/pm.pm_59_17 · Published 11 October 2017
Background: An increase in prevalence of diabetes mellitus necessitates the need to develop new drugs for its effective management. Plants and their bioactive compounds are found to be an alternative therapeutic approach…
Article
Biological Activity and Isolation of Compounds from Stem Bark of Plumeria acutifolia
Ghadah A. Alhozaimy, Ebtesam Saad Al‑Sheddi, Taghreed A. Ibrahim
pp. S505–S511 · DOI: 10.4103/pm.pm_22_17 · Published 11 October 2017
Background: Plumeria acutifolia (Apocynaceae) is an ornamental plant, used in the traditional medicine and known to have a variety of constituents as alkaloids, flavonoids, and iridoids. Extracts of this plant were prove…
Article
Correlation Between Polyphenol Oxidase (PPO) Activity and Total Phenolic Contents in Crocus sativus L. Corms During Dormancy and Sprouting Stages
Nardana Esmaeili, Hassan Ebrahimzadeh, Khosrou Abdi
pp. S519–S524 · DOI: 10.4103/0973-1296.216333 · Published 11 October 2017
Purification and characterization of polyphenol oxidase (PPO) enzyme and determination of total phenolic contents during dormancy and sprouting stages in Crocus sativus corms were performed. PPO enzyme was purified by am…
Article
Reversible Testicular Toxicity of Piperine on Male Albino Rats
Gopichand Chinta, Mohane Selvaraj Coumar, Latha Periyasamy
pp. S525–S532 · DOI: 10.4103/pm.pm_405_16 · Published 26 July 2017
Background: Piperine was widely used in traditional medicine for inducing sterility and abortion. Objective: To evaluate the effect of the piperine on testis of male albino rats. Materials and Methods: Adult male rats we…
Article
Methanolic Extract of Costus pictus D. DON Induces Cytotoxicity in Liver Hepatocellular Carcinoma Cells Mediated by Histone Deacetylase Inhibition
P. V. Neethu, K. Suthindhiran, M. A. Jayasri
pp. S533–S538 · DOI: 10.4103/pm.pm_524_16 · Published 11 October 2017
Background: Leaves of Costus pictus D. Don, (insulin plant) are used as dietary supplement for the treatment of diabetes. Objective: The antidiabetic activity of this plant is well documented, but its activity on differe…
Article
The Effect of Polyherbal Medicines Used for the Treatment of Tuberculosis on Other Opportunistic Organisms of Humans Infected with Tuberculosis
Elizabeth Bosede Famewo, Anna Maria Clarke, Anthony Jide Afolayan
pp. S539–S543 · DOI: 10.4103/pm.pm_468_16 · Published 11 October 2017
Background: In many immunocompromised patients, opportunistic bacterial and fungal infections are common. Polyherbal medicines examined in this study are used by the indigenous people of South Africa for the treatment of…
Article
Tyrosinase Inhibitory Activities of Carissa opaca Stapf ex Haines
Roots Extracts, Their Phytochemical Analysis Wajeeha Malik, Dildar Ahmed, Sania Izhar
pp. S544–S548 · DOI: 10.4103/pm.pm_561_16 · Published 11 October 2017
Objective: Carissa opaca is a medicinal plant with rich folkloric applications. The present research was conducted to explore the tyrosinase inhibitory potential of aqueous decoction (AD) and methanolic extract (ME) of r…
Article
Antiurolithiatic Potential of Neeri against Calcium‑Oxalate Stones by Crystallization Inhibition, Free Radicals Scavenging, and NRK‑52E Cell Protection from Oxalate Injury
Parveen Kumar Goyal, Santosh Kumar Verma, Anil Kumar Sharma
pp. S549–S554 · DOI: 10.4103/pm.pm_551_16 · Published 11 October 2017
Background: Neeri is a well‑established polyherbal formulation prescribed for renal stones by the physicians but has not been experimentally evaluated for its antiurolithiatic potential using cell‑lines. Objective: This …