Volume 14, Issue 56

14 August 2018 · pp. 275–470 · 27 articles

Volume: 14
Issue: 56
Published: 14 August 2018
Pages: 275–470
Articles: 27
Sections: 2
ISSN: Print - 0973-1296, Online - 0976-4062
Journal: PM

Original Article ORIGINAL ARTICLE

In this issue

Original Article

Article
Yukgunja‑tang, a Traditional Herbal Formula, Attenuates Cigarette Smoke‑induced Lung Inflammation in a Mouse Model
Eunsook Park, Woo‑Young Jeon, Chang‑Seob Seo, Hyekyung Ha, Seong Eun Jin, Jinhee Kim, Mee‑Young Lee
pp. 275–282 · DOI: 10.4103/pm.pm_351_17 · Published 14 August 2018
Background: Chronic obstructive pulmonary disease is a progressive lung disease that involves airway inflammation, chronic bronchitis, and emphysema. Yukgunja‑tang, one of the traditional Asian herbal medicines, has been…
Article
Alleviation of Doxorubicin‑induced Hepatic Toxicity with Fermented Cordyceps sinensis via Regulating Hepatic Energy Metabolism in Rats
Ping‑An Yao, Rong Wu, Yao‑Li Zhang, Xiao‑Hua Cui, Ke‑Zhao Wei, Xu Xu, Jian‑Ping Gao
pp. 283–289 · DOI: 10.4103/pm.pm_354_17 · Published 14 August 2018
Background: Cordyceps sinensis (CS), a traditional Chinese herbal medicine, has many pharmacological effects. Doxorubicin (DOX) is a spectrum antitumor drug, but it has toxicity to multiple organs. Objective: The objecti…
Article
Innovative Phytoformulation Containing Capsaicinoids: Microparticles Development, Analytical Method Validation, and Anti‑ulcer Effect
Martinha A. Almeida, Jessica M. Nadal, Traudi Klein, Josiane P. de Paula, Jane M. Budel, Andressa Novatski, Eliane A. Campesatto, Paulo V. Farago
pp. 290–296 · DOI: 10.4103/pm.pm_160_17 · Published 14 August 2018
Background: Capsicum annuum L. and Capsicum frutescens L., of family Solanaceae, contain capsaicinoids with several pharmacological effects. However, their pungency limits the long‑term use through the gastrointestinal t…
Article
Saponins from Rhizoma Panacis Majoris Attenuate Myocardial Ischemia/Reperfusion Injury via the Activation of the Sirt1/FoxO1/Pgc‑1α and Nrf2/Antioxidant Defense Pathways in Rats
Hai‑Bo He, Xiao‑Mei Li, Dao‑Jun Li, Yong‑Hong Ding, Yong‑Feng Zhang, Hai‑Yan Xu, Min‑Lu Feng, Chang‑Qing Xiang, Ji‑Gang Zhou, Ji‑Hong Zhang, Hong‑Jun Liu, Mao‑Hua Chen
pp. 297–307 · DOI: 10.4103/pm.pm_467_17 · Published 14 August 2018
Background: Saponins from Rhizoma Panacis Majoris (SRPM) are confirmed to have cardioprotective effect against myocardial ischemia injury by reducing oxidative stress, while its underlying mechanism has not been elucidat…
Article
Cytotoxicity of Sesquiterpenes Ferulenol and Coladin on Liver FAO and B16F1 Melanoma Cells
Malika Boulmeltout, Amar Zellagui, Lamia Benguedouar, Gillian Barratt, Mesbah Lahouel
pp. 333–337 · DOI: 10.4103/pm.pm_611_17 · Published 14 August 2018
Background: Ferula vesceritensis is an indigenous plant of Algerian Sahara riche in sesquiterpene coumarins. Objective: In this study, we investigated the biological activity of sesquiterpene coumarins; coladin, feruleno…
Article
Efficient Preparation of Narcissin from Opuntia ficus‑indica Fruits by Combination of Response Surface Methodology and High‑speed Countercurrent Chromatography
Guijae Yoo, Youngse Oh, Heejung Yang, Tae Bum Kim, Sang Hyun Sung, Seung Hyun Kim
pp. 338–343 · DOI: 10.4103/pm.pm_422_17 · Published 14 August 2018
Background: Narcissin is well known for their various biological activities. Objective: To recover narcissin from the Opuntia ficus‑indica fruits (OFIF), an efficient method was developed by a combination of response sur…
Article
The Effects of Emodin on Insulin Resistance in KKAy Mice with Diabetes Mellitus
Song Bing, Zhang Haoqiang, Ma Chunyu, Yu Yali, Wang Jing, Gao Yumeng, Zheng Hongwei, Liu Xuezheng
pp. 344–350 · DOI: 10.4103/pm.pm_362_17 · Published 14 August 2018
Background: Emodin can ameliorate insulin resistance in diabetes mellitus (DM), but the molecular mechanisms are still uncertain. Objective: The objective of this study is to identify the potential molecular mechanisms o…
Article
Efficacy of Momordica charantia L. on Blood Glucose, Blood Lipid, and Body Weight: A Meta‑analysis of Randomized Controlled Trials
Wiraphol Phimarn, Bunleu Sungthong, Kritsanee Saramunee, Wanida Caichompoo
pp. 351–358 · DOI: 10.4103/pm.pm_215_17 · Published 14 August 2018
Background: Previous studies reported that Momordica charantia (MC) improves several metabolic parameters, yet outcomes from numerous trials are contradictory. Objectives: This study aimed to assess MC efficacy for impro…
Article
T47D Cell‑inhibiting Indonesian Medicinal Plants and Active Constituents of Alpinia galanga Rhizome
Muhammad Da’i, Arini Fadhilah, Juwita Rahmawati, Alfian Mahardika Forentin, Tepy Usia, Maryati Maryati
pp. 359–363 · DOI: 10.4103/pm.pm_259_17 · Published 14 August 2018
Background: The screening of Indonesian medicinal plant extracts against T47D cell line and identifying active chemical constituents of Alpinia galanga rhizome were conducted. Materials and Methods: Thirty methanol extra…
Article
Ultra‑performance Liquid Chromatography/Quadrupole Time‑of‑flight Mass Spectrometry Analysis of In vitro Metabolites of Lignans from Fructus Forsythiae by Human Fecal Flora
Shihua Xing, Chongsheng Peng, Mengyue Wang, Ying Peng, Xiaobo Li
pp. 364–370 · DOI: 10.4103/pm.pm_177_17 · Published 14 August 2018
Background: Phillyrin and (+)‑pinoresinol 4‑O‑‑D‑glucoside are the major active furofuran‑type lignans in Fructus Forsythiae. The metabolic routes and metabolites of these two lignans are not well understood yet. Object…
Article
Hypericin, an Anthraquinone Derivative of Hypericum hookerianum Wight and Arn. (Hypericaceae) of Palni Hills, South India, Exhibits Anti‑Inflammatory Property in Lipopolysaccharide – Stimulated RAW 264.7 Macrophages
Mahendrakumar M, Seeni S, Perinbam K
pp. 378–382 · DOI: 10.4103/pm.pm_485_17 · Published 14 August 2018
Background: Hypericin is an anthraquinone derivative of Hypericum hookerianum, a shrub from Palni hills of Southern India which possess various medicinal values. Aim: The present study was aimed to evaluate the anti-infl…
Article
Protective Effect of Ethanol Extract of Cuscuta chinensis on Lipopolysaccharide‑induced Acute Kidney Injury via Suppressing the Toll‑like Receptors 4‑nuclear factor‑κB Pathway
Wu Song, Yuan Tao, Xiaofeng Yang, Xin‑yu Bai, Shuang Jiang
pp. 383–389 · DOI: 10.4103/pm.pm_343_17 · Published 14 August 2018
Background: The seed of Cuscuta chinensis Lam. (Cuscuta, Convolvulaceae), is widely used in traditional Chinese medicine, with a variety of biological activity. However, the efficacy of C. chinensis has not been investig…
Article
Full Extract of Euphorbia esula Reversed Chemoresistance, Inhibited Cell Migration/Invasion, and Induced Apoptosis of Multidrug‑resistant SGC7901/VCR Cells
Xianli Guo, Xiaodong Han, Ziwei Tian, Zhaoying Fu
pp. 411–417 · DOI: 10.4103/pm.pm_447_17 · Published 14 August 2018
Background: The plant Euphorbia esula has been used by ancient Chinese people to treat cancer and other ailments and is used by present doctors or folks as an assistant treatment for some kind of cancers, but the mode of…
Article
Suppression of Cervical Cancer Cell Survival by Ursolic Acid Extracted from Catalpa bungei Leaves
Hongyu Xu, Ziyun Zhou, Juane Dong, Ming Lei
pp. 425–431 · DOI: 10.4103/pm.pm_408_17 · Published 14 August 2018
Background: Previous phytochemical studies showed that extracts from leaves and seed oil of Catalpa plants showed antioxidant and antitumor activities. However, the active components and their roles and molecular mechani…
Article
Genotoxic Evaluation of Subcytotoxic Concentration of Cathine‑Rich Catha edulis in Human Peripheral Blood Lymphocytes
Syam Mohan, Manal Mohamed Elhassan Taha, Yahia A. Kaabi, Siddig Ibrahim Abdelwahab
pp. 432–436 · DOI: 10.4103/pm.pm_65_18 · Published 14 August 2018
Background: Catha edulis is an evergreen plant belonging to the Celastraceae family, used by the people of Africa, Yemen, and some part of Saudi Arabia as a recreational plant. They chew it alone or in combination with a…
Article
Chemical Profiles by Thin‑layer Chromatography and High‑performance Liquid Chromatography of Plant Species from Northeast Brazil
Julia Aparecida Lourenço de Souza, Wliana Alves Viturino da Silva, Isabelle Cristinne Ferraz Bezerra, Magda Rhayanny Assunção Ferreira, Luiz Alberto Lira Soares
pp. 437–443 · DOI: 10.4103/pm.pm_225_17 · Published 14 August 2018
Background: Fingerprint analysis plays a key role in quality control of herbal medicines due to its technical capacity to represent the chemical diversity of these complex matrices. Several traditional Brazilian species …
Article
Bioactivity‑Guided Isolation of Antioxidant Compounds from Pouzolzia zeylanica (L.) Benn
Lujun Wang, Die Gao, Qifeng Fu, Kai Zhou, Zhining Xia
pp. 444–450 · DOI: 10.4103/pm.pm_233_17 · Published 14 August 2018
Background: Pouzolzia zeylanica (L.) Benn. (Family: Urticaceae), which is widely distributed in China, is consumed as food and as a traditional herbal medicine for the treatment of numerous diseases. Objective: The aim o…
Article
Isolation and Characterization of Flavonoid C‑glycosides from Prosopis glandulosa Torr. Leaves
Neeraj Kumar Patel, L. M. Sharath Kumar, Jignesh Gajera, Atul N. Jadhav, Ganesh Muguli, U. V. Babu
pp. 451–454 · DOI: 10.4103/pm.pm_505_17 · Published 14 August 2018
Background: Prosopis glandulosa Torr. (Fabaceae) is native to Africa, America, and Asia. In India, it is abundantly found in southern parts. The plant is reported to contain polyphenols, flavonoids, mesquitol‑catechin di…
Article
Effects of Atractylodes Japonica Extract on Pacemaker Potentials Generated by Interstitial Cells of Cajal from Murine Small Intestine
Iksung Kim, Jung Nam Kim, Taewon Han, Eun Yeong Lim, Yun Tai Kim, Byung Joo Kim
pp. 455–460 · DOI: 10.4103/pm.pm_584_17 · Published 14 August 2018
Background: Atractylodes japonica has been commonly used to treat gastrointestinal (GI) disorders in Korean traditional medicine. Interstitial cells of Cajal (ICCs) are pacemaker cells in the GI tract and can regulate GI…
Article
Peroxisome Proliferator‑Activated Receptor‑γ Agonistic Effect of Chrysanthemum indicum Capitulum and Its Active Ingredients
Fuzi Zhang, Anna Iwaki, Kan’ichiro Ishiuchi, Akinori Sugiyama, Masahiro Ohsawa, Toshiaki Makino
pp. 461–464 · DOI: 10.4103/pm.pm_607_17 · Published 14 August 2018
Objective: The capitulum of Chrysanthemum indicum (Compositae) is the source of a crude drug used in Japanese traditional Kampo and traditional Chinese medicine. Previous research showed that C. indicum flowers promote a…
Article
In vitro Studies to Determine the Effect of Boeravinone B on Human Dendritic Cells
Praveen Kumar Posa Krishnamoorthy, Sivanandham Muthukumaran
pp. 465–470 · DOI: 10.4103/pm.pm_625_17 · Published 14 August 2018
Background: Boeravinone B (BB), a therapeutic biomarker isolated from roots of Boerhavia diffusa, possesses immunomodulatory properties. Objective: In the present study, we investigated cytotoxicity and immunomodulatory …

ORIGINAL ARTICLE

Article
Polar components of Phaleria macrocarpa Fruit Exert Antihypertensive and Vasorelaxant Effects by Inhibiting Arterial Tone and Extracellular Calcium Influx
Rabia Altaf, Muhammad Ihtisham Umar, Mohd Zaini Asmawi, Amirin Sadikun, Aidiahmad Dewa, Nurul Maizan Manshor, Nadiah Razali, Haroon Khalid Syed, Mohamed Khadeer Ahamed Basheer
pp. 312–321 · DOI: 10.4103/pm.pm_434_17 · Published 14 August 2018
Background: Phaleria macrocarpa (PM) has been used conventionally to cure hypertension. Objective: The objective of the study is to determine the active fraction and its chemical composition responsible for antihypertens…
Article
Immunostimulant Activity of Bergenia Extracts
Lenka Tumová, Helena Hendrychová, Doris Vokurková
pp. 328–32 · DOI: 10.4103/pm.pm_423_17 · Published 14 August 2018
Background: Bergenia species contain various therapeutically important compounds such as phenolic compounds‑arbutin, bergenin, tannins, gallic acid, flavonoids, minerals, and many others. Bergenia plants show antibacteri…
Article
Berberine Ameliorates Chronic Unpredictable Mild Stress Induced Depression Like Behaviors and Elevating Kelch-like Erythroid Cell-derived Protein with CNC Homology-associated Protein 1-nuclear Factor (Erythroid-derived 2)-like 2 Antioxidant Signaling Pathways
Wenqi Gao, Zhifang Deng, Xiaowen Liu, Jun Hu, Pengyi Deng, Leijuan Chi
pp. 371–7 · DOI: 10.4103/pm.pm_181_17 · Published 14 August 2018
Background: Studies have reported that depression is associated with increased level of oxidative stress and accompanied with decreased Kelch‑like erythroid cell‑derived protein with CNC homology‑associated protein 1‑nuc…
Article
Alpha-mangostin Suppresses Receptor Activator Nuclear Factor-κB Ligand-induced Osteoclast Formation and Bone Resorption in RAW264.7 Cells by Inhibiting the Extracellular Signal-Regulated Kinase and c-Jun N-Terminal Kinase Signaling
Rong-Hua Hong, Yi-Min Liang, Han-Song Pan, Zhao-Hui Cheng, Yong-Hua Li
pp. 390–6 · DOI: 10.4103/pm.pm_203_17 · Published 14 August 2018
Background: Excessive osteoclast formation and over‑activated function lead to a series of osteoclast‑related diseases. Suppression of osteoclastogenesis is likely to be an effective means for the treatment of these dise…
Article
Anti-inflammatory Activity of Total Alkaloids from Hypecoum leptocarpum Hook. f. et Thoms
Huaixiu Wen, Lei Jiang, Defang Zhang, Xiang Yuan, Jun Dang, Lijuan Mei, Yun Shao, Yanduo Tao
pp. 397–403 · DOI: 10.4103/pm.pm_139_17 · Published 14 August 2018
Background: Hypecoum leptocarpum Hook. f. et Thoms., which is used in traditional Tibetan medicine as an antipyretic, antitussive, analgesic, and anti‑inflammatory agent, contains a variety of alkaloids that could be res…
Article
Immunomodulatory Mechanism of Cordyceps militaris Polypeptide through Regulating Gene Hist1h2bp, Ctsg, and Elane in Mice
Guangyu Xu, Guangxin Yuan, Liping An, Peige Du, Liya Xie, Hongyu Li, Yu Sheng, Xiao Han
pp. 404–410 · DOI: 10.4103/pm.pm_412_17 · Published 14 August 2018
Background: Cordyceps militaris and Cordyceps sinensis belong to the same genus, but the different species, with immunity improvement, antibacterial, and antihypertensive effect, and the studies on the functions of C. mi…