Cover: Pharmacognosy Magazine
Pharmacognosy Magazine
Volume 14, Issue 57S
10 September 2018 · pp. 0–70 · 30 articles
- Volume
- 14
- Issue
- 57S
- Published
- 10 September 2018
- Pages
- 0–70
- Articles
- 30
- Sections
- 2
- ISSN
- Print - 0973-1296, Online - 0976-4062
- Journal
- PM
In this issue
Original Article
- Article
Solvent‑based Microwave‑assisted Extraction and Identification of Bioactive Compounds from Sesamum indicum Leaves using Particle Swarm Optimization‑integrated Response Surface Methodology
Lopamudra Sarma, Sourav Chakraborty, Raj Kumar Duary
pp. S275–S283 · DOI: 10.4103/pm.pm_570_17 · Published 10 September 2018
Background: Sesamum indicum is a widely cultivated crop with edible seeds which are well known for its rich antioxidant properties. The plant leaves have also been reported to have health functional attributes such as lo…
- Article
Evaluation of Antiangiogenic Potential of Psidium guajava Leaves using In‑Ovo Chick Chorioallantoic Membrane Assay
S. Latha, P. Yamini, Rajani Mathur
pp. S284–S293 · DOI: 10.4103/pm.pm_133_18 · Published 10 September 2018
Background: Angiogenesis is the process of formation of new blood vessels from the existing one. Pathological angiogenesis is widely implicated in many diseases, including cancer, diabetic neuropathy, retinopathy, obesit…
- Article
In vitro Antioxidant and Anticancer Activities of Leaf Extracts of Rhododendron arboreum and Rhododendron campanulatum from Uttarakhand Region of India
Sakshi Painuli, Swati Joshi, Anuja Bhardwaj, Ramesh Chand Meena, Kshipra Misra, Nishant Rai, Navin Kumar
pp. S294–S303 · DOI: 10.4103/pm.pm_15_18 · Published 10 September 2018
Background: Rhododendron arboreum and Rhododendron campanulatum are two important trees of Uttarakhand, known for their ethnopharmacological importance. In the present study, the aqueous and methanolic extracts of leaves…
- Article
Flavonoid and Phenolic Compounds from Carissa macrocarpa:
Molecular Docking, Cytotoxicity Studies Hany E. Khalil, Maged E. Mohamed, Mohamed A. Morsy, Mahmoud Kandeel
pp. S304–S310 · DOI: 10.4103/pm.pm_104_18 · Published 10 September 2018
Objective: The objective of the study is to investigate the phytochemical contents of the methanol extract of leaves of Carissa macrocarpa, the possible anticancer activities of the isolated compounds through molecular d…
- Article
Amelioration of Oxidative Stress through Apoptosis‑Mediated Pathway in Colon Cancer Cells by Hexane Fraction of Moringa oleifera Extract
Liang Jinghua, Sun Linmei, He Ping, Sivapragasam Gothai, Katyakyini Muniandy, S. Suresh Kumar, Norhaizan Mohd Esa, Palanisamy Arulselvan
pp. S311–S318 · DOI: 10.4103/pm.pm_284_17 · Published 10 September 2018
Background: Colorectal cancer (CRC) is one of the most common cancers worldwide and it is predicted that the number of cases will rise to 2.4 million by 2035. Therefore, preventative and therapeutic approaches are essent…
- Article
An Aspartic‑metalloprotease from an Endemic Plant Tuber (Burnatia enneandra micheli): Purification and Biochemical Characterization
Ngangoum Eric Serge, Mezajoug Kenfack Laurette Blandine, Sanjit Kumar, Tchiegang Clerge, Mookambeswaran Vijayalakshmi
pp. S319–S326 · DOI: 10.4103/pm.pm_555_17 · Published 10 September 2018
Background: The objective of this work was to isolate, optimize, and characterize protease from Burnatia enneandra which is an endemic plant found abundantly in the Far‑Nord Region of Cameroon. The optimum condition to e…
- Article
Metabolic Profiling and Expression Analysis of Key Genes during Leaf Maturation of Stevia rebaudiana Bertoni
Nazima Nasrullah, Javed Ahmad, Monica Saifi, Umara Rafiqi, Naved Quadri, Irum Gul Shah, Malik Zainul Abdin
pp. S327–S334 · DOI: 10.4103/pm.pm_554_17 · Published 10 September 2018
Background: Stevia (Stevia rebaudiana) is a plant of nutritional and industrial importance for its diverse steviol glycosides. Stevioside, rebaudioside-A and their aglycon steviol – 200-300 times sweeter than normal sucr…
- Article
Angiotensin‑Converting Enzyme Inhibitory Activity of Senna garrettiana Active Compounds: Potential Markers for Standardized Herbal Medicines
Fameera Madaka, Tossaton Charoonratana
pp. S335–S339 · DOI: 10.4103/pm.pm_325_17 · Published 10 September 2018
Background: Fifteen medicinal plants used in traditional Thai herbal medicine (HM) for hypertension treatment were previously tested for their inhibitory activity against an angiotensin‑converting enzyme (ACE). The ethyl…
- Article
Bio-Based Synthesised and Characterized Monodispersed Curcuma longa Silver Nanoparticles Induces Targeted Anticancer Activity in Breast Cancer Cells
Eram Sheikh, M. L. B. Bhatt, Madhu Tripathi
pp. S340–S345 · DOI: 10.4103/pm.pm_71_18 · Published 10 September 2018
Background: Among the various metal nanoparticles, plant extract‑based silver nanoparticles are gradually getting preference because the bioreduction potential of plant extracts is much faster for silver ions. The silver…
- Article
Phytochemical Investigation and Bioactivities of Alternanthera ramosissima (Mart.) Chodat and Hassl.
Sukanya Dej‑adisai, Sathianpong Phoopha, Jindaporn Puripattanavong
pp. S346–S351 · DOI: 10.4103/pm.pm_478_17 · Published 10 September 2018
Background: Since there are many researches of phytochemical and bioactivities from genus Alternanthera but did not have any reports from Alternanthera ramosissima. Objective: The objective of the study is to isolate, id…
- Article
Anti‑inflammatory Properties of Bixa Orellana Leaves Extract are Associated with Suppression of Bradykinin‑induced Endothelial Hyperpermeability
Yoke Keong Yong, Muhd Nazrul Somchit, Zuraini Ahmad
pp. S352–S357 · DOI: 10.4103/pm.pm_540_17 · Published 10 September 2018
Background: Previous study showed that an aqueous extract of Bixa orellana L. (Family of Bixaceae) leaf (AEBO) is capable of inhibiting bradykinin (BK)‑induced inflammation in animal models. Objective: This study further…
- Article
Ginsenoyne C, a Polyacetylene Isolated from Panax Ginseng Inhibit Inflammatory Mediators via Regulating Extracellular Regulated Kinases Signaling
Sun‑Yup Shim, Sang Hyun Sung, Mina Lee
pp. S358–S362 · DOI: 10.4103/pm.pm_58_18 · Published 10 September 2018
Background: Panax ginseng has been used as a traditional medicine for various pathological conditions. Ginsenoyne C (GSC) is a polyacetylene, minor constituent. Objective: The objective of the present study was to determ…
- Article
Cardioprotective Effect of Oregano Oil against Doxorubicin‑Induced Myocardial Infarction in Rats
Damita Lourdes Cota, V. P. Rasal, Sanjay Mishra, Sushant Shengule
pp. S363–S368 · DOI: 10.4103/pm.pm_70_18 · Published 10 September 2018
Aim: The objective of the study was to evaluate the cardioprotective effect of oregano oil (O.OIL) in doxorubicin (DOX)‑induced myocardial infarction (MI) in rats. Materials and Methods: O.OIL (100 mg/kg and 200 mg/kg, p…
- Article
In Vitro Antigastric Cancer Activity of Squalene, a Triterpenoid Compound Isolated from Rhizophora Mucronata Mangrove Plant Leaves against AGS Cell Line
Thirunavukkarasu Palaniyandi, Asha Sivaji, Ramanathan Thiruganasambandam, Sudhakar Natarajan, Rajeshwari Hari
pp. S369–S376 · DOI: 10.4103/pm.pm_577_17 · Published 10 September 2018
Background: Mangrove plants have high potential in medical research and they have been used in traditional medicine for any diseases. Squalene, a natural 30‑carbon triterpenoid compound, was originally obtained from Shar…
- Article
Antidiabetic, Toxicological, and Metabolomic Profiling of Aqueous Extract of Cichorium intybus Seeds
Kailash Chandra, Washim Khan, Sujata Jetley, Sayeed Ahmad, S. K. Jain
pp. S377–S383 · DOI: 10.4103/pm.pm_583_17 · Published 10 September 2018
Background: Cichorium intybus has a wide range of therapeutic applications in Indian traditional systems of medicine, especially in metabolic disorders. Objective: To evaluate the toxicity profile and to investigate the …
- Article
Identification of Phytoconstituents of Memecylon sisparense Gamble Leaf and Evaluation against Cisplatin‑induced Oxidative Renal Damage in Mice
Jaya Lakshmi Uppu, Veerabhadra Swamy Challa, Devender Bhattula, Ganga Modi Naidu Vegi, Malathi Jojula, Asha Syed
pp. S384–S392 · DOI: 10.4103/pm.pm_116_18 · Published 10 September 2018
Background: Memecylon sisparense Gamble (MSG) belongs to Melastomataceae family, having a wide range of pharmacological activities such as antioxidant, hepatoprotective, and anti‑inflammatory. Objective: The present stud…
- Article
Efficacy and Safety of Herbal Formulation Rich in Standardized Fenugreek Seed Extract as Add‑on Supplementation in Patients with Type 2 Diabetes Mellitus on Sulfonylurea Therapy: A 12‑week, Randomized, Double‑blind, Placebo‑controlled, Multi‑center Study
Amit D. Kandhare, Nadeem Rais, Nivedita Moulick, Alaka Deshpande, Prasad Thakurdesai, Sunil Bhaskaran
pp. S393–S402 · DOI: 10.4103/pm.pm_260_18 · Published 10 September 2018
Background: Type 2 diabetes mellitus (T2DM) is a chronic, complex, and progressive illness that often needs combination therapy for better glycemic control. IDM1, an herbal formulation which is rich in standardized fenug…
- Article
Evaluation of Biological Activity, Toxicity, and Phytochemical Content of Bowdichia virgilioides (Fabaceae) Aqueous Extract Isabela Bacelar Assis, Eliana Maria Mauricio da Rocha, Daniel Silqueira Martins Guimarães,
Glaécia Aparecida do Nascimento Pereira, Fabiana Paula Pereira, Jaqueline Maria Siqueira Ferreira, Emiliano O. Barreto
pp. S403–S408 · DOI: 10.4103/pm.pm_273_17 · Published 10 September 2018
Background: Antibiotic resistance is a worldwide problem that poses a serious threat to human health, limiting the therapeutic options for bacterial infections. The spread of falciparum‑resistant malaria is also concerni…
- Article
Phenotype Behavioral Impairment after the Administration of Xylopia Aromatica to Male Balb‑c Mice and Cytotoxicity to Breast and Cancer Cell Lines
Ivana Barbosa Suffredini, Mateus L. B. Paciencia, Bruna V. Santana, Humberto Vieira Frias, Cinthia Dos Santos Alves, Ingrit E. C. Díaz, Maria Martha Bernardi
pp. S409–S416 · DOI: 10.4103/pm.pm_373_17 · Published 10 September 2018
Background: Crude extract obtained from the stem of Xylopia aromatica (Annonaceae, EB149) known as pimenta‑de‑macaco, a traditional Brazilian medicinal and edible plant, showed cytotoxicity against leukemia cell lines. D…
- Article
Stimulation of Murine Immune Response by Clerodendrum infortunatum
Somit Dutta, Arnab Kumar Chakraborty, Pallab Kar, Priyankar Dey, Arnab Sen, Tapas Kumar Chaudhuri
pp. S417–S429 · DOI: 10.4103/pm.pm_549_17 · Published 10 September 2018
Background: Clerodendrum infortunatum is a medicinal plant found especially in the Sub‑Himalayan regions of West Bengal. Various tribal communities of this region have been using these plants as a source of natural medic…
- Article
Cytotoxicity Evaluation of Zingiber zerumbet Ethyl Acetate Extract on K-562, Erythroleukemia Cell Line
Asmah Hamid, Che Yang Aminah Ramly, Saiful Ridzuan Karim, Umi Noraashikin Zainudin, Nor Fadilah Rajab, Khairana Husain, Nurul Farhana Jufri
pp. S430–S433 · DOI: 10.4103/pm.pm_436_17 · Published 10 September 2018
Background: Zingiber zerumbet locally known as lempoyang is used traditionally to cure swelling, sores, and loss of appetite. Its rhizomes contain many active compounds such as zerumbone and kaempferol that have been sho…
- Article
The Reactive Oxygen Species/AMP‑Activated Protein Kinase Signaling Pathway’s Role in the Apoptotic Induction of MCF‑7 Human Breast Cancer Cells Caused by the Ethanol Extract of Citrus Unshiu Peel
Min Yeong Kim, Hyun HwangBo, Eun Ok Choi, Da He Kwon, Kyu Im Ahn, Seon Yeong Ji, Jin‑Woo Jeong, Su‑Hyun Hong, Cheol Park, Yung Hyun Choi
pp. S440–S447 · DOI: 10.4103/pm.pm_484_17 · Published 10 September 2018
Objective: Citrus unshiu Markovich, which has been used for many different purposes in traditional medicine, has been reported to possess various pharmacological properties; however, its anticancer potentials are relativ…
- Article
In vitro Anticholinesterase and Neurotoxicity Activities of Ocotea aciphylla Fractions
Monique Marylin A. de A. Carneiro, Rodrigo Souza Conceição, Isabella Mary Alves Reis, Alessandra Bispo Da Silva, Joana Da Luz Oliveira, Alexsandro Branco, Silvia Lima Costa, Mariana Borges Botura
pp. S448–S452 · DOI: 10.4103/pm.pm_366_17 · Published 10 September 2018
Background: Ocotea species are known to produce secondary metabolites with a range of biological activities. This study aimed to evaluate the in vitro acetylcholinesterase (AChE) inhibition and neurotoxicity activities o…
- Article
Bioconversion from Scutellaria baicalensis (baicalin) Feremted with Leatiporus sulphureus into Enriched‑Baicalein and Anti‑Wrinkle Effects
Mi‑Young Yun, Eun‑Young Won, Jung‑Hee Lee, Ju‑Im Jung, Hwa‑Jung Choi
pp. S453–S457 · DOI: 10.4103/pm.pm_32_18 · Published 10 September 2018
Background: Ultraviolet (UV) radiation causes photoaging in human skin. Phytochemicals from herbs have been used to treat various skin problems. Bioconversion of phytochemicals can increase efficacy and absorption rate b…
- Article
Naringenin Protects against 1‑Methyl‑4‑Phenylpyridinium‑ Induced Neuroinflammation and Resulting Reactive Oxygen Species Production in SH‑SY5Y Cell Line: An In vitro Model of Parkinson’s Disease
Sugumar Mani, Sathiya Sekar, Saravana Babu Chidambaram, Murugan Sevanan
pp. S458–S464 · DOI: 10.4103/pm.pm_23_18 · Published 10 September 2018
Background: Parkinson’s disease is a progressive neurodegenerative disorder which affects 1% of the population worldwide. It is well known that 1‑methyl‑4‑phenylpyridinium (MPP+) selectively and potentially inhibit Compl…
- Article
Ultra‑High‑Performance Liquid Chromatography‑Based Identification and Quantification of Thymoquinone in Nigella sativa Extract from Different Geographical Regions
Niyaz Ahmad, Rizwan Ahmad, Abdullah Al-layly, Hassan Al-shawi, Ahmed Al-ali, Mohd Amir, Ahmed Mostafa
pp. S471–S480 · DOI: 10.4103/pm.pm_119_18 · Published 16 August 2018
Background: Thymoquinone (THQ) is a major bioactive constituent of traditional medicinal plant such as Black seed (Nigella sativa, Family: Ranunculaceae). Objective: The objective of this study was to identify and quanti…
- Article
Ethnomedicinal Knowledge among the Tribes of the Little
Andaman Island, Andaman Andaman, Nicobar Islands, India M. Punnam Chander, Paluru Vijayachari
pp. S488–S493 · DOI: 10.4103/pm.pm_585_17 · Published 10 September 2018
Background: In Little Andaman Island, Onges is one of the particularly vulnerable Tribal Groups settled in Dugong Creek, whereas the Nicobarese tribe resides at Harminder Bay village. Having abode in the vicinity of the …
ORIGINAL ARTICLE
- Article
Chemoprotective Potential of Zingerone (Vanillyl Acetone) in Cyclophosphamide-induced Hepatic Toxicity
Bilal Ahmad Mir, Insha Amin, Muneeb U Rehman, Rahil Razak, Aarif Ali, Omer Khalil Baba, Bilques Fatima, Rayeesa Ali, Sheikh Bilal, Showkeen Muzamil, Isharq Hussain, S. Mudasir Rashid, Adil Farooq Wali, Manzoor-ur- Rahman Mir
pp. S434–9 · DOI: 10.4103/pm.pm_170_16 · Published 10 September 2018
Introduction: Cancer is one of the lethal diseases in the global world. Proliferation of cancer cells is commonly inhibited by chemotherapeutics. Cyclophosphamide (CP) is an alkylating chemotherapeutic agent often used f…
- Article
Terminalia chebula: A Promising Indigenous Phytotherapeutics for Alzheimer’s Disease
Roohollah Sobhani, Sivaprasad Mitra, Kripamoy Aguan
pp. S465–70 · DOI: 10.4103/pm.pm_402_17 · Published 16 August 2018
Introduction: Alzheimer’s disease (AD) is a progressive neurologic disorder that leads to the irreversible loss of neurons. Amyloid plaques and loss of cholinergic neurons are two main characteristics of AD. In AD, the a…
- Article
Molecular Docking and Density Function Theory Studies of Compounds from Euphorbia hirta and Bacopa monnieri to Zika Virus Structural and Nonstructural Proteins
Sangeetha Kothandan, Indu Purushothaman, Stella George, Sasikala Purushothaman, Meena Sulochana
pp. S481–7 · DOI: 10.4103/pm.pm_89_17 · Published 10 September 2018
Background: Zika virus is an arbovirus belongs to the genus flavivirus and pose a serious global threat. The recent 2015 outbreak in Brazil was associated with a significant increase in microcephaly cases and other neuro…