Volume 22, Issue 2

Original Research

1. Article

   AI-Driven pharmacy practice: Unleashing the revolutionary potential in medication management, pharmacy workflow, and patient care

   Dania Saad Rammal, Muaed Alomar, Subish Palaian

   pp. 1–11 · DOI: 10.18549/PharmPract.2024.2.2958 · Published 14 May 2024

   The integration of Artificial Intelligence (AI) in pharmacy practice holds great potential to revolutionize healthcare delivery and improve patient outcomes. AI can assist pharmacists in optimizing medication selection, …

2. Article

   Cost determinant of chemotherapy in breast, cervical, and lung cancer in the era of National Health Insurance

   Fitriana Yuliastuti, Tri Murni Andayani, Dwi Endarti, Susi Ari Kristina

   pp. 1–10 · DOI: 10.18549/PharmPract.2024.2.2957 · Published 15 April 2024

   Introduction: This study focuses on the financial burden of treating breast, cervical, and lung cancer in Indonesia. The prevalence and mortality rates of this cancer, particularly in the context of the National Health I…

3. Article

   The variations of selected serum cytokines involved in cytokine Storm after Omega-3 daily supplements: A Randomized Clinical Trial in Jordanians with vitamin D deficiency

   Rafeef AL Khaled, Jehad F. Alhmoud, Reem Issa, Heba A. Khader, Beisan A. Mohammad, Ahmad R. Alsayed, Khalid Abu Khadra, Maha Habash, Ahmad Aljaberi, Luai Hasoun, Mahmoud S. Abu-Samak

   pp. 1–10 · DOI: 10.18549/PharmPract.2024.2.2951 · Published 4 July 2023

   The aim of this study was to investigate the effects of supplementing unsaturated free fatty acids (n-3FA) on the levels of specific cytokines associated with cytokine storm in the blood of 72 Jordanian individuals (both…

4. Article

   Assessment of long-term safety and efficacy of Dupilumab therapy in patients with moderate-to-severe atopic dermatitis in the UAE: A real-life observational study

   Waqas S. Abdulwahhab, Sham ZainAlAbdin, Noor Al-Areqi, Imene Amrane, Ahmed AlHashmi, Omar AbuRuz, Amal Akour, Rami Beiram, Salahdein Aburuz

   pp. 1–11 · DOI: 10.18549/PharmPract.2024.2.2947 · Published 10 April 2024

   Background: Atopic Dermatitis (AD) is a chronic relapsing and remitting inflammatory skin disease characterized primarily scaly, pruritic, and erythematous skin lesions, all of which can have a profound negative impact o…

5. Article

   Assessing the impact of mobile-based interventions provided by pharmacists on glycemic control and diabetes related distress in adolescent patients with type 1 diabetes mellitus in Pakistan

   Nadia Hussain, Amal Hussain H.I. Haddad, Saima Abbass

   pp. 1–9 · DOI: 10.18549/PharmPract.2024.2.2946 · Published 14 May 2024

   Background: Diabetes is a chronic disease characterized by impaired insulin secretion, insulin resistance or both. Challenges in glycemic control for T1DM adolescents include hypoglycemic episodes and keeping the HbA1c w…

6. Article

   Practice, competency and attitude toward weight management service and the barriers for its implementation in the community pharmacy setting

   Anan S. Jarab, Walid Al-Qerem, Dua'a F. Mubarak, Shrouq R. Abu Heshmeh, Abdallah Y. Naser, Yazid N. Al Hamarneh, Amal Akour

   pp. 1–8 · DOI: 10.18549/PharmPract.2024.2.2937 · Published 2 May 2024

   Background: The World Health Organization has estimated that the prevalence of overweight and obesity in Jordan is up to 70% and 40% respectively. Identifying the community pharmacist's role is required to develop effect…

7. Article

   Antimicrobial potency of red and yellow varieties of grapefruit (Citrus Paradisi Macfad) grown in Jordan

   Malek A. Zihlif, Fatima Afifi, Ahmad Sharab, Paayam Maroof, Ala' Abu-Odeh, Ahmad R. Alsayed

   pp. 1–6 · DOI: 10.18549/PharmPract.2024.2.2932 · Published 8 May 2024

   Introduction: Worldwide, grapefruit is known to have medicinal values with antimicrobial, anti-inflammatory, antioxidant, and astringent propensities. Only a few researchers studied its antibacterial effects underlining …

8. Article

   The medicinal plants effects on the gene expression of cytochrome P450 and P-glycoprotein in cultured colon and breast cancer cell line

   Malek Zihlif, Neda Tanina, Abdelkader Batah, Khaled Tawaha, Shahd Qudsi, Luai Hasoun, Ahmad R. Alsayed

   pp. 1–7 · DOI: 10.18549/PharmPract.2024.2.2931 · Published 24 April 2024

   Using herbs in the Arab world is becoming increasingly common. Hence, there is a potential for pharmacokinetic and pharmacodynamic herb-drug interactions. Cytochrome P450 (CYP) enzymes and efflux transporter such as P-gl…

9. Article

   Protocol for systematic review and meta-analysis for randomized clinical trials on patiromer efficacy and safety in subjects with heart failure

   Asim Ahmed Elnour, Abdulla Shehab

   pp. 2714 · DOI: 10.18549/PharmPract.2024.2.2714 · Published 20 May 2024

   Background: We shall assess the efficacy and safety of patiromer in subjects with heart failure (HF) in randomized controlled trials (RCTs). Methods: The protocol has been developed supported the PRISMA-P checklist by us…

10. Article

    Awareness, knowledge, and behaviour of Jordanian public regarding misuse and overuse of proton pump inhibitors

    Mariam Ahmad Alameri, Lobna Gharaibeh, Mai I. AL-Hawamdeh, Randa Atwan, Enas Daoud

    pp. 2870 · DOI: 10.18549/PharmPract.2024.2.2870 · Published 17 May 2024

    Background: Proton pump inhibitors (PPIs) are frequently used for the treatment and prophylaxis of upper gastrointestinal tract disorders. PPIs are now frequently the first-choice treatment for people with diseases assoc…

11. Article

    Distribution of ACE gene I/D genotypes and clinical characteristics of patients with hypertension and COVID-19 in Indonesia

    Ingrid Faustine, Deli Marteka, Lisa Amelia, Shellinna Kurniawati, Amarila Malik, Retnosari Andrajati, Septelia Inawati Wanandi, Eko Supriyanto

    pp. 2914 · DOI: 10.18549/PharmPract.2024.2.2914 · Published Apr-Jun 2024

    Background: Suppression of the renin-angiotensin system by SARS-CoV-2 binding changes the balance between ACE and ACE2, which affects blood pressure regulation. The ACE gene polymorphisms in intron 16 are associated with…

12. Article

    Assessment of the efficacy and safety of favipiravir in patients with SARS-CoV-2 infection in United Arab Emirates: A single-center study

    Bayan Ayash, Sahab Alkhoujah, Neena Abraham, Ahmad El Ouweini, Sara Mansour, Syed Wassif Gillani, Rabih Hallit, Souheil Hallit, Diana Malaeb

    pp. 2917 · DOI: 10.18549/PharmPract.2024.2.2917 · Published 3 May 2024

    Background: Anti-viral medications are among the treatment options for coronavirus infectious disease 2019 (COVID-19) management although they are still not FDA approved for coronavirus treatment. We conducted the study …

13. Article

    Practices of community pharmacists during the COVID-19 pandemic: potential barriers and views on providing pharmacy services in Thailand

    Narumol Jarernsiripornkul, Kamonphat Wongtaweepkij, Disorn Pason, Thanyaporn Namwan

    pp. 2933 · DOI: 10.18549/PharmPract.2024.2.2933 · Published 1 May 2024

    Background: Community pharmacists have played an essential health service role during the Coronavirus Disease 2019 (COVID-19) outbreak. Practices of community pharmacists against the pandemic may differ based on the spec…

14. Article

    Effect of weekly high-dose vitamin D3 supplementation on the association between circulatory FGF-23 and A1c levels in people with vitamin D deficiency: A randomized controlled 10-week follow-up trial

    Sara M. Alimam, Jehad F. Alhmoud, Heba A. Khader, Ahmad R. Alsayed, Mohammad Abusamak, Beisan A. Mohammad, Ibrahim Mosleh, Khaled Abu Khadrah, Ahmad Aljaberi, Maha Habash, Luai Hasoun, Mahmoud S. Abu-Samak

    pp. 2934 · DOI: 10.18549/PharmPract.2024.2.2934 · Published 2 May 2024

    Purpose: This randomized clinical trial (RCT) was designed to assess the effect of vitamin D supplementation (VD3) on the relationship between the levels of fibroblast growth factor-23 (FGF-23) and osteocalcin factor (OS…

15. Article

    Antiretrovirals and frequently prescribed medications in people living with HIV: Potential drug-drug interactions detected by three online-databases

    Apisada Jiso, Kanaporn Thiengtham, Athikhun Suwannakhan, Nunnaphat Sirijaraswan, Phisit Khemawoot, Somnuek Sungkanuparph

    pp. 2940 · DOI: 10.18549/PharmPract.2024.2.2940 · Published Apr-Jun 2024

    Background: Since the advent of antiretroviral therapy, HIV infection, which was once considered a life-threatening condition, can now be managed as a chronic disease. People infected with HIV have high prevalence rates …

16. Article

    Systematic review and meta-analysis of individualized enoxaparin dose optimization in critically ill pediatrics: A path towards enhanced therapeutic outcomes

    Mohammed Kanan, Nawaf M. Alotaibi, Khalid Bin Anzan, Hayat Alzahrani, Ghaliah Ibrahim, Fatmah Shamakhi, Anhar Al-Mohsin, Noura Alhutarshi, Shaden Alotaibi, Renad Almutairi, Reem Alshammari, Asma Alshammari, Hanaa Almedali, Reem Alkhedair, Dalia Alhabeeb

    pp. 2948 · DOI: 10.18549/PharmPract.2024.2.2948 · Published 18 April 2024

    Background: Critically ill pediatric patients face an increased risk of venous thromboembolism, and enoxaparin is commonly used for prophylaxis and treatment. However, optimal dosing in this population remains uncertain,…

17. Article

    Evaluation of Drug-Related Problems in the Chronic Kidney Disease Clinic at the University Hospital in Thailand

    Sathaporn Khananthai, Angsunid Porncatatak, Malinporn Jampong, Natchaya Ingpongpun, Supattra Pinsamsay, Supatat Chumnumwat, Sayamon Sukkha

    pp. 2949 · DOI: 10.18549/PharmPract.2024.2.2949 · Published 2 May 2024

    Background: The chronic kidney disease (CKD) clinic plays a vital role in providing comprehensive ambulatory care for patients with CKD. Pharmacists contribute to ensuring proper drug use and identifying potential drug-r…

18. Article

    Natural agents’ role in cancer chemo-resistance prevention and treatment: molecular mechanisms and therapeutic prospects

    Anas Abed, Malek Zihlif, Heba A Khader, Luai Hasoun, Amniyah Al-Imam, Mahmoud J Al Shawabkeh, Leen B Fino, Alhareth A. Alsa’d, Mustafa Al-Shajlawi, Ahmad R. Alsayed

    pp. 2950 · DOI: 10.18549/PharmPract.2024.2.2950 · Published Apr-Jun 2024

    Cancer is a leading cause of morbidity and mortality worldwide, necessitating exploring novel preventive and therapeutic strategies. Over the years, the potential of natural agents in cancer prevention and treatment has …

19. Article

    Pharmacists' perception of evidence-based practice and experience in over-the-counter counseling: A cross-sectional study in Japan

    Nanako Uchiyama, Masaki Shoji, Mitsuko Onda

    pp. 2952 · DOI: 10.18549/PharmPract.2024.2.2952 · Published 7 May 2024

    Background: Evidence-based practice (EBP) is essential for pharmacists to select and recommend over-the-counter (OTC) drugs in medical consultations (hereinafter referred to as OTC counseling). Objectives: This study exa…

20. Article

    Look-alike/sound-alike medication errors: An in-depth examination through a hospital case study

    Teeraporn Sadira Supapaan, Ananya Songmuang, Jintana Napaporn, Parichat Sangsukwow, Pornchanok Boonrod, Phonrawin Intarapongsakul, Aporn Jaturapattarawong, Chonladda Pitchayajittipong

    pp. 2959 · DOI: 10.18549/PharmPract.2024.2.2959 · Published 7 May 2024

    Background: Look-alike/sound-alike (LASA) drugs substantially contribute to global healthcare challenges and patient harm, necessitating a comprehensive understanding of LASA medication errors. Objective: The current stu…

21. Article

    Clinical interventions of community pharmacies for diarrhea management: Evidences from developing countries

    Mohammed Kanan, Arwa Alqhatani, Wajan Khalid, Salwa Alzuhairy, Sara Almohammadi, Majed Alsubaie, Raneem Baaqeel, Faisal Alshammari, Kholoud Alshammari, Haifa S. Albalawi, Abeer M. Albalawi, Zainab A. Alrashid, Maha Aloudah, Abdullah Alzayed, Nawaf M. Alotaibi

    pp. 2962 · DOI: 10.18549/PharmPract.2024.2.2962 · Published 14 May 2024

    Diarrhea is a significant health concern in developing countries, particularly among children under the age of five. Community pharmacies (CPs) play a vital role in managing diarrhea by providing guidance and referrals. …

22. Article

    Incidence, outcomes, and risk factors of antituberculosis drugs induced liver injury in Thailand: A retrospective cohort study

    Pattaraporn Akkahadsee, Sirot Jantharaksa, Ratree Sawangjit, Panumart Phumart

    pp. 2965 · DOI: 10.18549/PharmPract.2024.2.2965 · Published Apr-Jun 2024

    Background: Tuberculosis (TB) is a persistent health concern in numerous regions, including Thailand. The adverse effects of tuberculosis (TB) treatments, particularly liver injuries, can complicate treatment protocols, …

23. Article

    A Systematic review on randomized clinical trials for direct oral anticoagulant in subjects with acute coronary syndrome: primary and secondary outcomes

    Nadia AlMazrouei, Asim Ahmed Elnour, Israa Yousif Al-Khidir, Fai Mutaz Alharbi, Hajer Shaty Alshammari, Shroog Farhan Altwalah, Aliyah Hamdan Alshammari, Talal Ahmed Alshammari, Ibrahim Khalid Alhajaji, Majd Habib Alshammari, Norah Abdulmuthri Aljohani, Yasmin Khaled Alshammari, Shahd Eid Alanazi, Semira Abdi Beshir, Vineetha Menon

    pp. 3032 · DOI: 10.18549/PharmPract.2024.2.3032 · Published 23 May 2024

    Background: In recent years, direct oral anticoagulant (DOAC) has been projected for secondary prevention of recurrent ischemic events post-acute coronary syndrome (ACS). However, there is still uncertainty about the eff…