Volume 14, Issue 3

2025 · pp. 497–809 · 41 articles

Volume: 14
Issue: 3
Published: 2025
Pages: 497–809
Articles: 41
Sections: 3
ISSN: e-ISSN: 2278-5957 | p-ISSN: 2278-747X
Journal: AJBLS

Review Article Original Article Case Report

In this issue

Review Article

Review
Microbial L-Asparaginase Bio betters: Therapeutic Potential in Cancer Treatment and beyond
Neenu Pius, C. Mallikarjuna Reddy, P. Praveen Reddy
pp. 497–505 · DOI: 10.5530/ajbls.20250011 · Published
Microbial enzymes are utilized in a variety of fields. They find applications in several industries, including baking, leather tanning and brewing, among others. Recently microbial enzyme bio betters have been used as th…
Review
Therapeutic Potentials of Cinnamomum zeylanicum Blume (Twak), Bridging Ayurveda and Contemporary Science
Pragati V Kotur, Geeta G Gadad
pp. 506–517 · DOI: 10.5530/ajbls.20250007 · Published
Cinnamomum zeylanicum Blume. (Twak), is widely used in Ayurveda for its therapeutic properties. A systematic screening of PubMed, Scopus, Web of Science, and Google Scholar (2014-2024) was conducted alongside an analysis…
Review
Review on the Phytochemical and Neuro-Pharmacological Potential of Convolvulus prostratus Forssk (Convolvulaceae)
Kavya Vishnu, Kochuthressia K.P, Sinjumol Thomas
pp. 518–526 · DOI: 10.5530/ajbls.20250003 · Published
The therapeutic potential of Convolvulus prostratus Forssk (C. prostratus) has been valued in traditional medicine for years, and its immense pharmacological properties have recently been revealed. Phytochemicals such as…
Review
Tooth Resorption: A Comprehensive Review of Pathophysiology, Classification, Diagnosis and Management
Charishma Chowdary Ponugubati, Ravichandra Ravi
pp. 527–531 · DOI: 10.5530/ajbls.20250016 · Published
Tooth resorption refers to the loss of dental hard tissues, including dentin, cementum, or bone, due to physiological or pathological processes. Although initially observed in the 16th century, its etiologies, classifica…
Review
Unveiling Tigliane Derivatives as Novel Therapeutics for Alzheimer's Disease
Kausik Bhar, Sumanta Mondal, Kazi Asraf Ali, Saptarshi Samajdar
pp. 532–540 · DOI: 10.5530/ajbls.20250029 · Published
Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder with limited therapeutic options. Current treatments offer only symptomatic relief without halting disease progression. Natural products and their deri…
Review
Artificial Intelligence in Medical Prescription: Revolution, Risks and Future Aspects
Shital Chaudhari, Tularam Barot
pp. 541–546 · DOI: 10.5530/ajbls.20250039 · Published
The integration of Artificial Intelligence (AI) into medical prescription systems has transformed modern medicine. With tools such as DrugGPT and Clinical Decision Support Systems (CDSS), AI helps clinicians evaluate pat…
Review
Optimizing Women's Health-Utilising Phytochemicals for Functional Food Development
Rashmi H Poojara, Soumya P S, Alvina Rose, Niva Somarajan
pp. 547–559 · DOI: 10.5530/ajbls.20250056 · Published
Objectives:The major objective of this review is to systematically evaluate and synthesize recent evidence on functional foods and phytochemicals in relation to women’s health outcomes. Functional foods have emerged as a…
Review
A Scoping Review on the Methods Adopted and Rationale Applied for Therapeutic Administration of Ghee or Oil as a Purificatory Regimen
Divya Manikandan, Muhasina Manalilparambil Basheer, Shitha Thomas, Abhilash Mangampadath, Seena Sukumaran
pp. 560–568 · DOI: 10.5530/ajbls.20251536 · Published
Snehapana (therapeutic intake of ghee /oil) is a specific modality of treatment uniquely mentioned in Ayurveda. It involves the oral administration of medicated oil or ghee to attain specific therapeutic goals. Snehana t…
Review
Siddha Herbal Formulations in Dental Care: A Comprehensive Review of Traditional Remedies
Suresh Ramasamy, Shanmugapriyan Pazhani, Abarna Balasubramani, Shanmu Radhakrishnan, Karthic Vedhachalam Mani
pp. 569–573 · DOI: 10.5530/ajbls.20250078 · Published
Oral health is a critical component of overall well-being, yet dental diseases remain widespread due to factors like poor hygiene and limited awareness. Traditional systems like Siddha medicine offer valuable insights in…

Original Article

Article
Identification of Bioactive Compounds in Meha Mudgara Rasa Using Gas Chromatography-Mass Spectrometry (GC-MS): Implications in Diabetic Neuropathy
Shailesh Deshpande, Meha Gandhi
pp. 574–585 · DOI: 10.5530/ajbls.20250008 · Published
Introduction: Diabetic Neuropathy (DN) is a progressive and debilitating complication of Diabetes Mellitus (DM), primarily caused by chronic hyperglycaemia-induced microvascular damage to peripheral nerves. Despite exist…
Article
Assessment of Effect of Comorbidities on Quality of Life of Pancreatitis Patients Using SF36V1
Nukabathini Jessica, Danthala Srujana, Mehedi Hasan, Mohd Azharuddin, M. Chinnaeswaraiah
pp. 586–592 · DOI: 10.5530/ajbls.20250017 · Published
Introduction: Painful inflammation of the pancreas in the upper abdomen is a common risk factor for acute pancreatitis, affecting individuals of all ages, especially newborns. Risk factors include alcohol consumption, ga…
Article
Antibacterial Properties of Cow Urine Collected from a Badri Calf
Mansi Arya, Shikha Bora, Nagma Parveen, Deepak Chandra Melkani, Gaurav Rawat, Netra Pal Sharma, Satpal Singh Bisht
pp. 593–597 · DOI: 10.5530/ajbls.20250010 · Published
Background:This study investigates the antibacterial potential of Badri cow urine against various pathogenic bacteria, including Pseudomonas aeruginosa, Aeromonas salmonicida, Escherichia coli, Listeria monocytogenes, an…
Article
Evaluation of the Anthelmintic Potential of Pongamia pinnata Root Hydroalcoholic Extract against Tubifex tubifex
Shaon Dey, Kousik Saha, Urmistha Sarkar, Krishanu Pramanick, Sanjib Manna, Riju Koley, Santanu Manna, Priya Roy
pp. 598–602 · DOI: 10.5530/ajbls.20250026 · Published
Background: Pongamia pinnata is a well-known plant traditionally employed in the treatment of various ailments. This study was conducted with the objective of evaluating the anthelmintic property of a hydroalcoholic extr…
Article
Estimation of Secondary Metabolites and Antibacterial Potential of Perilla frutescens (L.) Britton Leaf Extract against Human Pathogens
Suman Khanduri, Chandni Pundir, Neha Kumari, Seema Gupta, Maneesha Singh
pp. 603–611 · DOI: 10.5530/ajbls.20251523 · Published
The present investigation was undertaken to explore the potential of Bhangjeera [Perilla frutescens (L.) Britton], family Lamiaceae as a source of antibacterial agents against human pathogenic bacteria, along with qualit…
Article
Assessment of Risk Factors and Cost-Effective Analysis of Antibiotics in Urinary Tract Infections
Bairaboyina Tejasri, Konduri Raveendra Babu, Mamidi Sankirthana, Buddi Akhila, Guthikonda Tharun Kumar, Maram Chinnaeswaraiah
pp. 612–616 · DOI: 10.5530/ajbls.20250031 · Published
Objectives:Using an analysis test that is cost-efficient, determining which antibiotic therapy is most effective among several antibiotics. And to deliver superior care at a lower cost, to evaluate the risk factor that c…
Article
Evaluation of Acute Toxicity (LC50) and Biochemical Response of Labeo rohita (Hamilton 1822) to Crystal Violet Dye Exposure
Archana B. Dhandale, Sachinkumar. R. Patil, Surat. A. Manjare
pp. 617–624 · DOI: 10.5530/ajbls.20251530 · Published
Background:Crystal Violet (CV) dye has been widely used in dye processing industries and also used to provide a deep violet colour to paints and printing ink. It is a topical antimicrobial agent that inhibits cell replic…
Article
Acorus calamus Exhibiting Antidiabetic Activity: An in vitro and in silico Approach
Saptarshi Samajdar
pp. 625–635 · DOI: 10.5530/ajbls.20250022 · Published
Background: Diabetes mellitus is a multifaceted metabolic disorder characterized by chronically elevated blood glucose levels. Existing therapeutic strategies often present limitations such as adverse toxicity and the em…
Article
Phytochemical Screening and Anthelmintic Activity of Hydroalcoholic Extract of Leaves of Sphaeranthus indicus
Katta Vinith Reddy, Chikkudu Vinay, Yeluguri Vinay, Subiya Tahniyat, Mohd Azharuddin, Maram Chinnaeswaraiah
pp. 636–640 · DOI: 10.5530/ajbls.20250023 · Published
Background: The traditional uses form the basis of the evaluation and confirmation of the pharmacological properties of various plant species which makes the clinical claims extremely vital. Variably, medicinal plants ha…
Article
Antimicrobial Activity of Punica granatum, Citrus sinensis, Musa acuminata Fruit Peel and Applications in Food Preservation
Rashmi H Poojara, Gopika N R, Unnimaya Ashok
pp. 641–645 · DOI: 10.5530/ajbls.20250040 · Published
This study evaluated the antimicrobial, antifungal, antioxidant, and phytochemical properties of ethanolic extracts derived from the peels of Punica granatum (pomegranate), Citrus sinensis (orange), and Musa acuminata (b…
Article
Development and Validation of UV Spectroscopic Method for Estimation of Propranolol in Bulk and Tablet Dosage Form
Gundeboina Sowjanya, Rezwan Ahmed, Mohammad Sanaha, Yelgaboina Naresh, Badavathu Raja, Vemuluri Padmabhushana Chary, Maram Chinnaeswaraiah
pp. 646–652 · DOI: 10.5530/ajbls.20250030 · Published
Background:Propranolol is a widely used non-selective beta-blocker prescribed for hypertension, arrhythmias, and anxiety -related conditions. Simple, robust, and cost-effective analytical methods are essential for its ro…
Article
Instrumental Analysis of Siddha Antidote Surai Karuppu
Chandrabose Yogeswari, Vijayalakshmi Rajendran, Ariharikrishnan Kannan, Abarna Balasubramani, Shanmugapriya Ponnappan, Madhavan Ramachandran
pp. 653–656 · DOI: 10.5530/ajbls.20250049 · Published
Background: Lagenaria siceraria (Mol.) Standl., commonly known as bottle gourd, is a medicinal plant from the Cucurbitaceae family with established therapeutic potential. In Siddha medicine, purified Lagenaria siceraria …
Article
Production and Characterization of Antimicrobial Metabolites from Streptomyces rochei Strain SC1 against Multi-Drug-Resistant Escherichia coli
Sanjay Chavan, Bhagvat Lad, Tukaram Kadam
pp. 657–665 · DOI: 10.5530/ajbls.20250054 · Published
Objectives: Streptomyces rochei have ability to synthesize a variety of antimicrobial compounds which exhibit antibacterial, antifungal, and even anticancer activities. S. rochei may have ability to produce bioactive com…
Article
Phytochemical Potential of Heliotropium marifolium (J. kocnig ex Retz.)- An in vitro Antioxidant and Antidiabetic Analysis
Srinivasan Nithya, Edward Gnanaraj Wesely, Helan Soundra Rani Michael, Musthapha Shabana Begum
pp. 666–671 · DOI: 10.5530/ajbls.20250060 · Published
This study aimed to assess the antioxidant, anti-inflammatory, and α-amylase inhibitory activities of H. marifolium leaf and stem extracts using in vitro assays to validate its pharmacological potential. Antioxidant assa…
Article
Designing Novel Angiotensin Receptor Blockers and their Antihypertensive Potentials
Denis Malsawmzela, Pawi B. Lalthanpuii, Lalnunhruaitluangi L, Lalzikpuii Sailo, Bawitlung Lalruatfela, Kholhring Lalchhandama
pp. 672–688 · DOI: 10.5530/ajbls.20250063 · Published
Background: Hypertension is a pervasive and incurable disease that requires an effective management throughout life. Sartans are the most commonly used prescription drugs. These drugs are specific angiotensin II receptor…
Article
Bioaccumulation of Heavy Metals in Freshwater Invertebrates of the Kallada River, India: Implications for Ecological Risk and Food Safety
Tarunpal Chandrapal Soumini, Reshmi Vijayan, Byju Hameed, Maitreyi Hegde
pp. 689–695 · DOI: 10.5530/ajbls.20250048 · Published
Background: Rivers are crucial freshwater ecosystems that sustain biodiversity, livelihoods, and essential ecosystem services, but face increasing contamination from industrial, domestic, agricultural, and mining activit…
Article
Role of Consanguinity on Pediatric Haematological and Pulmonary Health: A Comparative Study at a Tertiary Care Teaching Hospital, Guntur, Andhra Pradesh
Sai Pranathi Sravani Chintaluri, Sreeja Chinnam, Santosh Kumar Katta, Pavan Kumar Yanamadala, Srinivasa Rao Kambam, Ramesh Kumar Banala, Rama Rao Nadendla
pp. 696–702 · DOI: 10.5530/ajbls.20250062 · Published
Background:Consanguineous marriage, characterised as a union between individuals who are second cousins or closer, continues to be culturally significant in certain regions of India and is linked to heightened homozygosi…
Article
Scientific Understanding of Prustha Basti and Its Application in Degenerative Disc Diseases by Oil Pulling: A Panchakarma Therapy
Kanji Poriya, Vipin Kumar, Sonu S, Hardik Chudasama
pp. 703–708 · DOI: 10.5530/ajbls.20250061 · Published
Background/Aim: Prustha Basti is an external Panchakarma procedure in which warm medicated oil is retained over the spinal region using a dough ring made of black gram flour. Degenerative Disc Disease (DDD) is a progress…
Article
Effect of Ectoparasitism on Length-Weight Relationship and Condition Factor of Five Fish Species in River Penna, Kadapa, Andhra Pradesh
Anu Prasanna Vankara
pp. 709–718 · DOI: 10.5530/ajbls.20250066 · Published
Objectives: This study investigates the impact of ectoparasitic infections on Length-Weight Relationships (LWR) and condition factor of five freshwater fishes of River Penna, Kadapa, Andhra Pradesh from three sampling si…
Article
PGPB Consortium Promotes Drought Tolerance in Capsicum frutescens
Bea Christayeen M. Custodio, Jaquelyn A. Diño, Alyssa Ashley H. Payumo, Liwayway P. Taglinao
pp. 719–727 · DOI: 10.5530/ajbls.20250065 · Published
Objectives: This study evaluated the potential of a bacterial consortium-Bacillus cereus, Micrococcus luteus, Klebsiella pneumoniae, and Pseudomonas aeruginosa-to enhance drought tolerance in Capsicum frutescens L. seedl…
Article
Like and Subscribe to Yourself: Social Media's Influence on Undergraduate and Postgraduate Students’ Identity Formation
Pavan Kumar Yanamadala, Arifah Naaz Shaik, Vijay Arijilli, Devika Sai Lakshmi Burlagadda, Sailesh Tej Sai Sree Babu Yarra, Avinash Chowdary Chirumamilla, Karthik Satharajupalli, Rama Rao Nadendla
pp. 728–733 · DOI: 10.5530/ajbls.20251528 · Published
Background: The extensive incorporation of social media into the everyday experiences of Generation Z has significantly altered their self-perception and their interactions with their environment. This transformation has…
Article
Kinetics of Using Gossypium arboreum Shell Activated Carbon for Batch Adsorption of Chromium Ions from Aqueous Solution
Saravanakumar Ganesan, Arivoli Shanmugam, Maran Mariappan
pp. 734–741 · DOI: 10.5530/ajbls.20250021 · Published
Aim/Background: Gossypium arboreum (Shell), was utilized as an adsorbent to extract the Cr ion from aqueous solution. Materials and Methods: The shell had a particle size of 53 to 150 μm. The influence of pH demonstrates…
Article
Effect of Roasting on Functional Properties, Phytochemical Composition and Antioxidant Activity of Watermelon Seed Flour
Ifa Imran, Namitha Prastheena Joseph
pp. 742–746 · DOI: 10.5530/ajbls.20250058 · Published
Background:Watermelon seeds are byproducts of watermelon with significant nutritional, therapeutic and functional potentials but they are often discarded as waste. The present study analyzed the effect of roasting on the…
Article
Privacy Preservation of Genomic and Medical Data
Sahiti Chamarthy, Nageswara Rao Moparthi, Kommaragiri Raghava Rao, Venkata Rakesh Chintala, Janaki Ramaiah Mekala, Charanya Gade, Reshitha Talluri
pp. 747–757 · DOI: 10.5530/ajbls.20251484 · Published
Background:Cancer, characterized by abnormal and uncontrolled cell division, is a major global health concern and a prominent area of research. When a patient is diagnosed with a medical condition, their data is collecte…
Article
Formulation and of Commiphora caudata (Wight and Arn.) Engl.:- Herbal Wound Healing Ointment
Adinath Vishvanth Munde, Palanisamy Pethappachetty, Maharudra Shamrao Rakh
pp. 758–765 · DOI: 10.5530/ajbls.20250014 · Published
Aim: The present study explores compatibility studies, analysis, physiochemical parameters of formulated ointment with herbal wound healing ointment activity. Materials and Methods: Commiphora caudata bark ethanolic extr…
Article
The Evolutionary Relationship of Indian Skimmer Dragonflies (Odonata: Libellulidae): A Molecular Perspective
Hardeep Singh Hansra, Gurinder Kaur Walia, Gagandeep Kaur Dhillon
pp. 766–773 · DOI: 10.5530/ajbls.20250072 · Published
Background: This study addresses the challenging classification of the diverse Libellulidae (skimmer dragonflies) using molecular systematics. Materials and Methods: By analyzing the mitochondrial COI gene for 21 Indian …
Article
Prevalence of Chronic Kidney Disease in Meghalaya, India: A Retrospective Study
Kathrina Marbaniang, Barry Cooper Hynniewta, Cordilia Kharkrang, Susa Teidaka Sayoo, Probin Phanjom
pp. 774–779 · DOI: 10.5530/ajbls.20250075 · Published
Objectives: To evaluate the prevalence of chronic renal disease in patients attending a tertiary care hospital in Meghalaya, India. Materials and Methods: A retrospective study was carried out in the dialysis unit of Civ…
Article
Method Development and Validation of Acyclovir by UV Spectrophotometric Method
Badavathu Raja, Mohammad Amatul Haq-Kubra, Gunaganti Lakshmi Prasanna, Bura Naga Sri, Bakkidul Islam, Maram Chinnaeswaraiah
pp. 780–786 · DOI: 10.5530/ajbls.20250033 · Published
Background: Acyclovir, an antiviral agent active against herpes simplex virus types I and II and varicella zoster, is widely used in pharmaceutical formulations. Existing pharmacopoeial methods employ non-aqueous titrati…
Article
Characterization of Pathogenic Bacterial Bioaerosols in Polluted Freshwater Lakes in Southern India: Implications for Public Health
Jerusha Ann Thomas, Byju Hameed, Maitreyi Hegde
pp. 787–793 · DOI: 10.5530/ajbls.20250079 · Published
Background:Bioaerosols are airborne microbial particles that pose a threat to the environment and human health. Materials and Methods:Bacterial bioaerosol samples were collected following standard protocols with a respir…
Article
Evaluation of Bio-efficacy of Calotropis procera Against Juvenile Stage of Common Household Pest Periplaneta americana (American Cockroach)
Kalim Shaikh, Tanvir Pathan, Wasim Shaikh, Rafik Shaikh
pp. 794–798 · DOI: 10.5530/ajbls.20250013 · Published
Aim/Background: The present study aimed to evaluate the effects of Calotropis procera (Aiton) W.T. Aiton against the juvenile stage of common household pest Periplanata americana (American Cockroach). Materials and Metho…
Article
Evaluation of Acalypha indica Aerial Part Ethanol Extract for Anticancer Activity in MDA-MB-231 Cells Supported by GC-MS Chemical Fingerprinting
Rajadurai Ancy, Selva Mabel Parimala
pp. 799–805 · DOI: 10.5530/ajbls.20250071 · Published
Background:Plant extracts, their parts, and active chemicals are used for many decades in cancer management. Aim:In this study, the aerial part (stems, leaves and flowers) of Acalypha indica (Family: Euphorbiaceae) was c…

Case Report

Article
Clinical Diagnosis of Empty Sella Syndrome: A Case Report from Meghalaya
Kathrina Marbaniang, Ethan Van Lal Rinngheta, Rimiki Challam, Barry Cooper Hynniewta, Kyrshan Giri Lynrah, Lumlang Buhphang
pp. 806–809 · DOI: 10.5530/ajbls.20250074 · Published
Empty Sella Syndrome is a significant problem that can impair hormonal function in patients and is frequently misdiagnosed due to its common asymptomatic nature. A case study of a 60-year- old patient from Meghalaya with…