Volume 51, Issue 4

Ghode Piyush, Jain Sanmati Kumar

pp. 664–671 · DOI: 10.5530/ijper.51.4.98 · 2017

Background: Type-2 diabetes mellitus can be effectively treated with dipeptidyl peptidase- IV inhibitors. Diverse classes of molecules have exhibited promising DPP-IV inhibition. Objective: In this perspective, 3D-QSAR a…

Nguyen Ngan, Mac Giang, Nguyen Tu

pp. 672–678 · DOI: 10.5530/ijper.51.4.99 · 2017

Background: Black garlic has become more popular in Vietnam due to its interesting biological activities. Purpose: The quality of different black garlic preparations should be checked. Methods: 1010 colony forming units …

Rizwana Kausar, Naveed Akhtar

pp. 679–683 · DOI: 10.5530/ijper.51.4.100 · 2017

Introduction: It has been indicated from previous research that strawberry consumption may be beneficial to improve skin appearance and its extract has antioxidant and antiinflammatory effects. Objective: The aim of pres…

Nazanin Ataee, Jamshid Fooladi, Mohammad Hasan Namaei, Fateme Mirzajani

pp. 684–691 · DOI: 10.5530/ijper.51.4.101 · 2017

Background: Codeine and morphine are important pharmaceuticals having analgesic characteristics. Aim: The current study used response surface methodology to optimize the biotransformation of thebaine into codeine and mor…

Patil Shriniwas Pramod, Kumbhar Subhash Trimbakrao, Ambhore Vanita

pp. 692–699 · DOI: 10.5530/ijper.51.4.102 · 2017

Background: Lantana camara L. leaves have been traditionally claimed to be used in treatment of different illnesses. Leaves are rich in lower terpenes in the form of essential oil, however they also contain lipids like w…

Emel Sönmez, Yavuz Bülent Köse

pp. 700–705 · DOI: 10.5530/ijper.51.4.103 · 2017

Background: Ajuga species are anthelmintic, diuretic, antifungal, and antimycobacterial agents.Lamiaceae members Ajuga postii Briq. and Ajuga relicta P.H.Davis are local endemic species of Turkey. Aim: To give informatio…

Sanjay Javerilal Surana, Anilkumar Uttamchand Tatiya, Mohan Ganpatrao Kalaskar

pp. 706–712 · DOI: 10.5530/ijper.51.4.104 · 2017

Objective: To evaluate the effect of the successive extracts of the FMB on ethanol induced chronic hepatotoxicity. Furthermore, to understand the mechanisms of its pharmacological actions, the in vivo antioxidant activit…

Ravi Mundugaru, Senthil Kumar Sivanesan, Padmaja Udaykumar, Febin Joy, Sunil Kumar Koppala Narayana, Lekshmi Rajakrishnan, Al Farhan Ahmed Abdullah Bin Hamad, Thomas Jacob, Rajakrishnan Rajagopal, Sameh Mohammed Hisham

pp. 713–721 · DOI: 10.5530/ijper.51.4.105 · 2017

Fruit rind of Garcinia pedunculata is one of the important medicinal plant and a condiment used in Indian kitchen. In spite of many medicinal properties ascribed to this species, less of pharmacological studies are carri…

Mukesh K. Singh, Hemant Dhongade, Dulal Krishna Tripathi

pp. 722–728 · DOI: 10.5530/ijper.51.4.106 · 2017

Objective: Evaluation of the cytotoxic effect of different extracts of Orthosiphon pallidus Royle on MCF-7 cell lines, comparatively. Materials and Methods: The breast cell line MCF-7 was cultured in DMEM medium containi…

Anila Raslin, Sekar Sathiya, Chidambaram Saravana Babu, Johanna Rajkumar

pp. 729–739 · DOI: 10.5530/ijper.51.4.107 · 2017

Objective: To evaluate the hepatoprotective effect of Ambrex, a polyherbal formulation against D–galactosamine (D-GLN) induced hepatotoxicity in Swiss albino mice as well as in Chang liver cell lines. Materials and Metho…

Sahoo Jyotirmaya, Paidesetty Sudhir Kumar

pp. 740–747 · DOI: 10.5530/ijper.51.4.108 · 2017

The antipyrinyl derived molecules are a versatile building blocker organic compounds and used in medicinal drug research. A versatile range of hybrid molecules have been synthesized by diazotization of 4-aminoantipyrin a…

Shambuling Karabasannavar, Parvati R Allolli, Basavaraj M. Kalshetty

pp. 748–757 · DOI: 10.5530/ijper.51.4.109 · 2017

Objective: The main aim of the present work was to synthesize a novel Schiff base ligand 2-hydroxy-3-((4-(4-phenylthiazol-2-yl) semicarbazide) methyl) benzoic acid is obtained by the condensation of N-(4-phenylthiazole-2…

Nadeem Ahmed Farooqui, Mousumi Kar, Ravindra Pal Singh, Sanjay Jain

pp. 758–764 · DOI: 10.5530/ijper.51.4.110 · 2017

The aim of the present research work was to characterize the ex-vivo, in-vitro and in-vivo studies of proniosomal (PN) gel of ketorolac tromethamine (KT). Experimental work: Proniosomal suspension was prepared by rotator…