Volume 55, Issue 4

Original Article(continued)

1. Article

   In silico Investigation and Molecular Docking Study of Triazolo-thiadiazole Derivatives for Antimicrobial, Anti-inflammatory and Anti-diabetic Activity

   Amol Sopanrao Dighe, Ashim Kumar Sen

   pp. 1125–1144 · DOI: 10.5530/ijper.55.4.213 · 2021

   Triazolo-thiadiazole and connected fused ring in heterocyclic compounds are of highly interest in potential bioactive molecules. Triazolo-thiadiazole derivatives have lead of organic chemists due to their good biological…

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2. Article

   Synthesis, Characterization and Antidiabetic Evaluation of Sulfonamide in Corporated with 1,3,4-Oxadiazole Derivatives

   Megha Tukaram Salve, Shailaja Bhanudas Jadhav Sr

   pp. 1145–1150 · DOI: 10.5530/ijper.55.4.214 · 2021

   Aim/Background: There is an increasing prevalence of diabetes mellitus throughout the world, and new compounds are necessary to combat this. While the current available antidiabetic therapies are long-term complicated an…

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3. Article

   1,3,4-thiadiazole Attached 2, 3- disubstituted Thiazolidinones Derivatives: Synthesis and Biological Evaluation

   Ashish Garg, Sweta Garg

   pp. 1151–1163 · DOI: 10.5530/ijper.55.4.215 · 2021

   Background: Thiazolidinone derivatives are the subject of prominent importance since they have been seen as valuable intermediates for the formulating/synthesize of different heterocyclic derivatives and it gives various…

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4. Article

   Application of Augmented Simplex Centroid Design for Optimization of HPLC Mobile Phase for Estimation of Curcumin and Piperine

   Jahnavi Naik, Sonal Desai, Vinodkumar Ramani

   pp. 1164–1172 · DOI: 10.5530/ijper.55.4.216 · 2021

   Background: Optimization of mobile phase for high performance liquid chromatography (HPLC) is an exigent task where one factor at a time (OFAT) approach is not preferable as it is time consuming specially for multifacete…

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5. Article

   Development and Validation of Analytical Method for Quantitative Estimation of Multiple Metal Impurities in Dobutamine Hydrochloride using ICPMS Spectroscopy

   Sayyad Kousr Ali, Tanmoy Mondal

   pp. 1173–1182 · DOI: 10.5530/ijper.55.4.217 · 2021

   Objectives: Primary objective of the present study is to develop and validate an accurate and linear analytical method for precise estimation of Vanadium, Cobalt, Nickel, Arsenic, Cadmium, Mercury, Thallium and Lead elem…

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6. Article

   Molecular Characterization of Genetic Diversity of Plasmodium falciparum Associated with Imported Cases of Malaria in Southeastern Region of Saudi Arabia

   Lorina I Badger-Emeka, Abdulrahman A Al Sultan, Ahlam A Al Qatari, Abdullatif Sami Al Rashed, Ahmed Al Sayyah

   pp. 1183–1196 · DOI: 10.5530/ijper.55.4.218 · 2021

   Growing global international travel has reflected significantly on the number of imported cases of malaria into non endemic regions of the world inclusive of Saudi Arabia were transmission of the disease is significantly…

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7. Article

   Evaluation of iceA1 Gene Expression of Helicobacter pylori Risk Factor of Gastric Cancer in Transgenic Brinjal

   Mohammad Javad Mehran, Basaralu Yadurappa Sathish Kumar, Nanjundappa Haraprasad, Rambod Barzigar, Bashasab Fakrudin, Sayan Paul

   pp. 1197–1206 · DOI: 10.5530/ijper.55.4.219 · 2021

   Background: The advancement of plant biotechnology improved crop production by revolutionizing plant science. Humans were commonly infected by Helicobacter pylori, and it was closely linked to stomach ulcers and cancer. …

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8. Article

   Implementation of Quality by Design (QbD) Approach in Development of QCT-SMEDDS with Combination of AgNPs for Diabetic Foot Ulcer Management

   Reena Badhwar, Ruchi Singh, Tinku, Harvinder Popli

   pp. 1207–1223 · DOI: 10.5530/ijper.55.4.220 · 2021

   Introduction: Quercetin (QCT) is a flavonoid with antioxidant, potential free radical scavenger, and strong anti-inflammatory activities. These properties of QCT promote wound healing process. Objectives: The present wor…

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