Volume 56, Issue 2S

Praveen Kumar, Mariam Mammen, Aswathy Madhusoodhanan, Archana Geetha Mohanan, Pradeep Kumar Ravindrannair, Anilkumar Appu Kuttan, Sheeba Madhavan Sathi, Mathew Steephan

pp. S121–S136 · DOI: 10.5530/ijper.56.2s.83 · 2022

Drug repurposing is the remodeling of already existing drugs to reduce the time frame, costs, and efforts in developing a new novel drug. This strategy has secured significant momentum in the previous decade. It overcome…

Jobin Jose, Abdul Haseeb K, Anu Jose, Shifali S, Simi P Thomas, Prasant Nayak

pp. S137–S145 · DOI: 10.5530/ijper.56.2s.84 · 2022

Patent protection is the exclusive rights to protect the invention which forbid the manufacture, use, distribution or trade of the invention by others unless they get permission from the patentee. Patent is granted to th…

Shailendra S Suryawanshi, Mahesh S Palled

pp. S152–S162 · DOI: 10.5530/ijper.56.2s.86 · 2022

Background: Metformin (MET) is an oral antidiabetic agent falls chemically under the category of biguanides and it is effectively utilized in the management of type 2 diabetes mellitus. It is marketed in the tablet dosag…

Jithu Jerin James, Sandhya Kadamboor Veethil, Joysa Ruby Joseph Rajarathinam

pp. S163–S170 · DOI: 10.5530/ijper.56.2s.87 · 2022

Objectives: Pyrolytic oil of coconut shell was obtained by the fast pyrolysis method. This research aimed to identify the use(s) of pyrolytic oil in topical pharmaceutical formulations. The study included extraction of b…

Rao Monica Raghavendra Prasad, Pardeshi Amol A

pp. S171–S180 · DOI: 10.5530/ijper.56.2s.88 · 2022

Introduction: This study involves development and evaluation of bioavailability of oral self-nanoemulsifying drug delivery system of BCS class II and IV drugs, Artemether and Lumefantrine (AL), respectively. This fixed c…

Babita Agarwal, Sachin Jagdale, Santosh Gandhi

pp. S181–S188 · DOI: 10.5530/ijper.56.2s.89 · 2022

Introduction: In order to establish stability indicating techniques to comprehend the degradation behavior of drug under stress environments and to establish degradation pathway for drug substance, forced degradation is …

Ashwini M, Preethi Sudheer, Bharani S. Sogali, Chandramouli R

pp. S189–S199 · DOI: 10.5530/ijper.56.2s.90 · 2022

Aim/Background: In the present study Glyburide, a hypoglycaemic agent was loaded into nanostructured lipid carriers. The solid and liquid lipid concentrations within the formulation were optimized using central composite…

Manish Kumar Singh, Rupa Mazumder, Swarupanjali Padhi, Dinesh Kumar Singh

pp. S200–S215 · DOI: 10.5530/ijper.56.2s.91 · 2022

Introduction: The drugs belonging to BCS class III, create various challenges for the development of sublingual dosage form due to poor absorption through sublingual mucosa. The sublingual drug delivery is suitable for p…

Swarnali Das Paul, Rohitas Deshmukh, Simran Kukreja

pp. S216–S224 · DOI: 10.5530/ijper.56.2s.92 · 2022

Background: Nasal route of drug administration has gained popularity nowadays specially for drugs acting on nasopulmonary area. Atazanavir is an antiviral drug which has proved efficacy in different viral infection inclu…

Veerendra K M, Rajashree S Masareddy, Archana S Patil, Udaykumar Bolmal

pp. S225–S234 · DOI: 10.5530/ijper.56.2s.93 · 2022

Ticagrelor is a new generation Adenosine diphosphate receptor inhibitor drug which is highly lipohilic having poor aqueous solubility used in the treatment of Acute Coronary Syndrome and prevention of Thrombotic events l…

Archana Patil, Bhakti Kauthankar, Satish Kavatagimath, Rajashree Masareddy, Panchaxari Dandagi

pp. S235–S244 · DOI: 10.5530/ijper.56.2s.94 · 2022

Background: Glyburide is an oral antidiabetic agent with a shorter half-life and is practically insoluble in water. As a result, there is a need to enhance the drug solubility with a aim to improve drug absorption via th…

Ankita Patel, Richa Dayaramani

pp. S245–S252 · DOI: 10.5530/ijper.56.2s.95 · 2022

The first line therapies in many acne diagnoses include application of retinoic acid derivatives for improvement in acne severity. Though, it has been observed that, current available formulations are sensitive to skin a…

Ranjit Prasad Swain, Bharat Bhusan Subudhi

pp. S253–S264 · DOI: 10.5530/ijper.56.2s.96 · 2022

Introduction: To improve the aqueous solubility and bioavailability of nateglinide, we have earlier used poloxamer 188 and 407. Since solutol HS 15 and cremophor RH 40 are compatible and scalable polymers for industrial …

Madhusudhan Meka, Krishnaji Rao Mutyala, Radha Gadela, Ganapathy Seru

pp. S265–S273 · DOI: 10.5530/ijper.56.2s.97 · 2022

Aim: The objective of the presented study is to evaluate the acute dermal and ocular irritation of herbal shampoos consisting of a mixture of plant extracts. Materials and Methods: Both studies performed using New Zealan…

Ruo-Fei Huang, Lin-Lin Xu, Tian-Xi Chen, Ke Li, Jing-Yao Xia, Hui-Shang Wang

pp. S274–S280 · DOI: 10.5530/ijper.56.2s.98 · 2022

Background and Aim:Epimedii folium is a widely used herbal medicine with numerous medicinal effects. In this study, we aimed to investigate the effects of Epimedii folium polysaccharide (EFP) in db/db metabolic disorder …

Swati Dobhal, Mamta F Singh, Sonal Setya, Shradha Bisht

pp. S281–S293 · DOI: 10.5530/ijper.56.2s.99 · 2022

Background: Lemongrass (Cymbopogon citratus) is widely used as a folklore medication for treating obesity and diabetes. The present study evaluates the comparative effect of ethanolic and aqueous extract and essential oi…

Jayapal Sharath, Rafi Ahmed Shahin Taj, Mahadevaiah Bhagya

pp. S294–S302 · DOI: 10.5530/ijper.56.2s.100 · 2022

Introduction: The naturally available herbs are used for medicinal purpose to promote health. The leaves of Argemone mexicana is one such herb used against different ailments. However, studies involving the characterizat…

Pragati Khare, Kamal Kishore, Dinesh Kumar Sharma

pp. S303–S311 · DOI: 10.5530/ijper.56.2s.101 · 2022

Objectives: The present study aimed at investigating the protective role of Madhuca longifolia ethanolic leaf extract flavonoid fraction against colchicine induced cognitive dysfunction and oxidative damage in swiss albi…

Ulku Karaman, Tayyibe Beyza Yucel, Tugba Cebeci, Yeliz Kasko Arici, Murat Yucel, Busra Korkmaz

pp. S312–S325 · DOI: 10.5530/ijper.56.2s.102 · 2022

Aim/Background: Seaweeds are unicellular or multicellular vegetative organisms and have a wide distribution. Their antitumoral, antiviral, antifungal, insecticidal, cytotoxic, and phytotoxic and antiproliferative activit…

Anjna Rani, Sunil Kumar, Roop K Khar

pp. S326–S338 · DOI: 10.5530/ijper.56.2s.103 · 2022

Background: Phytosome is a novel technique introduced by Indena that combines standardised herbal extract and phospholipid in preferably equal ratio to provide better absorption enhancing bioavailability. Purpose: The ob…